Orientation dependence of progressive post-yield behavior of human cortical bone in compression
Open accessAbstract
Identifying the underlying mechanisms of energy dissipation during post-yield deformation of bone is critical in understanding bone fragility fractures. However, the orientation-dependence of post-yield properties of bone is still poorly understood. Thus, the objective of this study was to determine the effect of loading direction on the evolution of post-yield behavior of bone using a progressive loading protocol. To do so, cylindrical compressive bone samples were prepared each in the longitudinal, circumferential and radial directions, from the mid-shaft of cadaveric femurs procured from eight middle-aged male donors (51.5 ± 3.3 years old). These specimens were tested in compression in a progressive loading scheme. The results exhibited that the elastic modulus, yield stress, and energy dissipation were significantly greater in the longitudinal direction than in the transverse (circumferential and radial) directions. However, no significant differences were observed in the yield strain as well as in the successive plastic strain with respect to the increasing applied strain among the three orientations. These results suggest that the initiation and progression of plastic strain are independent of loading orientations, thus implying that the underlying mechanism of plastic behavior of bone in compression is similar in all the orientations.
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Bone Mechanical Properties in Healthy and Diseased States
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- Authors
- Dong, X. N., Acuna, R. L., Luo, Q., & Wang, X.
- Affiliations
- The University of Texas at Tyler (US)
- The University of Texas at San Antonio (US)
- Peking University (CN)
- Corresponding author
- Wang, Xiaodu
- Venue
- Journal of Biomechanics
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 45
- Issue
- 16
- Pages
- 2829-2834
- ISSN
- 0021-9290 (ISSN-L)
- PMC
- PMC3582028
- OpenAlex
- W2121857899
- Cited by
- 68
- References
- 39
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 7 · 2023: 4 · 2022: 8 · 2021: 11 · 2020: 12 · 2019: 3 · 2018: 4 · 2017: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 1
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Biomechanics (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH/NIAMS (1R01AR055955)
- NSF/CREST (HRD-0932339)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Epidemiology › Bone fractures and treatments
- Physical Sciences › Engineering › Biomedical Engineering › Elasticity and Material Modeling
- Keywords
- cortical bone, compression, post-yield behavior, orientation dependence, loading direction, energy dissipation, plastic strain, yield stress, elastic modulus, fragility fractures, femur, progressive loading
- MeSH terms
- Femur, Humans, Male, Middle Aged, Stress, Mechanical, Viscosity, Elastic Modulus
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