Characterization of lipid and fatty acids composition of Chlorella zofingiensis in response to nitrogen starvation
Abstract
Cellular biochemical composition of the microalga Chlorella zofingiensis was studied under favorable and nitrogen starvation conditions, with special emphasis on lipid classes and fatty acids distribution. When algal cells were grown in nitrogen-free medium (N stress), the increase in the contents of lipid and carbohydrate while a decrease in protein content was detected. Glycolipids were the major lipid fraction (50.7% of total lipids) under control condition, while neutral lipids increased to be predominant (86.7% of total lipids) under N stress condition. Triacylglycerol (TAG) content in N stressed cells was 27.3% dw, which was over three times higher than that obtained under control condition. Within neutral lipids fraction, monounsaturated fatty acids (MUFA) were the main group (40.6%) upon N stress, in which oleic acid was the most representative fatty acids (34.5%). Contrarily, glycolipids and phospholipids showed a higher percentage of polyunsaturated fatty acids (PUFA). Lipid quality assessment indicated the potential of this alga as a biodiesel feedstock when its neutral lipids were a principal lipid fraction. The results demonstrate that the neutral lipids content is key to determine the suitability of the microalga for biodiesel, and the stress cultivation is essential for lipid quality.
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Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works
Chisti, Y. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2007.02.001 · Cited by 9,524 · see citing works
Microalgal triacylglycerols as feedstocks for biofuel production: perspectives and advances
Hu, Q., Sommerfeld, M., Jarvis, E., Ghirardi, M., Posewitz, M., Seibert, M., & Darzins, A. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03492.x · Cited by 3,745 · see citing works
Ho, S., Chen, C., & Chang, J. (2011) · Bioresource Technology · doi:10.1016/j.biortech.2011.11.133 · Cited by 781 · see citing works
Improving biodiesel fuel properties by modifying fatty ester composition
Knothe, G. (2009) · Energy & Environmental Science · doi:10.1039/b903941d · Cited by 702 · see citing works
Liu, J., Huang, J., Sun, Z., Zhong, Y., Jiang, Y., & Chen, F. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.06.017 · Cited by 419 · see citing works
Talebi, A. F., Mohtashami, S. K., Tabatabaei, M., Tohidfar, M., Bagheri, A., Zeinalabedini, M., Mirzaei, H. H., Mirzajanzadeh, M., Malekzadeh-Shafaroudi, S., & Bakhtiari, S. (2013) · Algal Research · doi:10.1016/j.algal.2013.04.003 · Cited by 390 · see citing works
Msanne, J., Xu, D., Konda, A. R., Casas-Mollano, J. A., Awada, T. N., Cahoon, E. B., & Cerutti, H. D. (2012) · Phytochemistry · doi:10.1016/j.phytochem.2011.12.007 · Cited by 389 · see citing works
Bigogno, C. (2002) · Phytochemistry · doi:10.1016/s0031-9422(02)00100-0 · Cited by 387 · see citing works
Yoon, K., Han, D., Li, Y., Sommerfeld, M. R., & Hu, Q. (2012) · The Plant Cell · doi:10.1105/tpc.112.100701 · Cited by 377 · see citing works
Accumulation of astaxanthin and lutein in Chlorella zofingiensis (Chlorophyta)
Campo, J. A. D., Rodr�guez, H., Moreno, J., Vargas, M. A., Rivas, J., & Guerrero, M. G. (2004) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-003-1510-5 · Cited by 324 · see citing works
Gao, C., Zhai, Y., Ding, Y. M., & Wu, Q. (2009) · Applied Energy · doi:10.1016/j.apenergy.2009.09.006 · Cited by 304 · see citing works
Fidalgo, P., Cid, Á., Torres, E., Sukenik, A., & Herrero, C. (1998) · Aquaculture · doi:10.1016/s0044-8486(98)00278-6 · Cited by 273 · see citing works
Production of astaxanthin by the green microalga Chlorella zofingiensis in the dark
Ip, P.-F., & Chen, F. (2005) · Process Biochemistry · doi:10.1016/j.procbio.2004.01.039 · Cited by 270 · see citing works
Fan, J., Yan, C., Andre, C., Shanklin, J., Schwender, J., & Xu, C. (2012) · Plant and Cell Physiology · doi:10.1093/pcp/pcs082 · Cited by 248 · see citing works
Nitrogen Starvation Induced Oxidative Stress in an Oil-Producing Green Alga Chlorella sorokiniana C3
Zhang, Y., Chen, H., He, C., & Wang, Q. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069225 · Cited by 247 · see citing works
Mujtaba, G., Choi, W., Lee, C., & Lee, K. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.07.057 · Cited by 243 · see citing works
Zhu, S., Huang, W., Xu, J. H., Wang, Z., Xu, J., & Yuan, Z. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.10.092 · Cited by 241 · see citing works
Self-citationEffect of phosphorus on lipid accumulation in freshwater microalga Chlorella sp.
Liang, K., Zhang, Q., Gu, M. H., & Cong, W. (2012) · Journal of Applied Phycology · doi:10.1007/s10811-012-9865-6 · Cited by 219 · see citing works
Ho, S.-H., Huang, S.-W., Chen, C.-Y., Hasunuma, T., Kondo, A., & Chang, J.-S. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2012.10.100 · Cited by 216 · see citing works
Lei, A., Chen, H., Shen, G., Hu, Z., Chen, L., & Wang, J. (2012) · Biotechnology for Biofuels · doi:10.1186/1754-6834-5-18 · Cited by 211 · see citing works
Levine, R. B., Costanza‐Robinson, M. S., & Spatafora, G. A. (2010) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2010.08.035 · Cited by 189 · see citing works
Feng, P., Deng, Z., Fan, L., & Hu, Z. (2012) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2012.05.007 · Cited by 165 · see citing works
Recht, L., Zarka, A., & Boussiba, S. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-3940-4 · Cited by 162 · see citing works
Zhu, L., Wang, Z., Takala, J. A., Hiltunen, E., Qin, L., Xu, Z., Qin, X., & Yuan, Z. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.03.144 · Cited by 150 · see citing works
Self-citationProduction potential of Chlorella zofingienesis as a feedstock for biodiesel
Liu, J., Huang, J., Fan, K. W., Jiang, Y., Zhong, Y., Sun, Z., & Chen, F. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.05.082 · Cited by 148 · see citing works
MacDougall, K. M., McNichol, J. C., McGinn, P. J., O’Leary, S. J. B., & Melanson, J. E. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-5376-6 · Cited by 143 · see citing works
Mansour, M. P., Volkman, J. K., & Blackburn, S. I. (2003) · Phytochemistry · doi:10.1016/s0031-9422(03)00052-9 · Cited by 129 · see citing works
Huo, S., Wang, Z., Zhu, S., Zhou, W., Dong, R., & Yuan, Z. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.07.012 · Cited by 124 · see citing works
Self-citationPopovich, C. A., Damiani, C., Constenla, D., Martínez, A. M., Freije, H., Giovanardi, M., Pancaldi, S., & Leonardi, P. I. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.02.121 · Cited by 86 · see citing works
Chia, M. A., Lombardi, A. T., Melão, M. D. G. G., & Parrish, C. C. (2013) · European Journal of Phycology · doi:10.1080/09670262.2012.750687 · Cited by 66 · see citing works
Gonçalves, E., Johnson, J. V., & Rathinasabapathi, B. (2013) · Planta · doi:10.1007/s00425-013-1946-5 · Cited by 65 · see citing works
Popovich, C. A., Damiani, C., Constenla, D. T., & Leonardi, P. I. (2011) · Journal of Applied Phycology · doi:10.1007/s10811-010-9639-y · Cited by 59 · see citing works
Zhou, X., Xia, L., Ge, H., Zhang, D., & Hu, C. (2013) · Bioresource Technology · doi:10.1016/j.biortech.2013.03.169 · Cited by 48 · see citing works
The Green Microalga Chlorella saccharophila as a Suitable Source of Oil for Biodiesel Production
Herrera-Valencia, V. A., Pool, P. Y. C., López-Adrián, S., Peraza-Echeverría, S., & Barahona-Pérez, L. F. (2011) · Current Microbiology · doi:10.1007/s00284-011-9956-7 · Cited by 47 · see citing works
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Microalgae as Sources of High-Quality Protein for Human Food and Protein Supplements
Wang, Y., Tibbetts, S. M., & McGinn, P. J. (2021) · Foods · doi:10.3390/foods10123002 · Cited by 342 · see citing works
Self-citationZarrinmehr, M. J., Farhadian, O., Heyrati, F. P., Keramat, J., Koutra, E., Kornaros, M., & Daneshvar, E. (2020) · Egyptian Journal of Aquatic Research · doi:10.1016/j.ejar.2019.11.003 · Cited by 227 · see citing works
Nitrogen and phosphorus stress as a tool to induce lipid production in microalgae
Maltsev, Y., Kulikovskiy, M., & Maltseva, S. (2023) · Microbial Cell Factories · doi:10.1186/s12934-023-02244-6 · Cited by 174 · see citing works
“It is reported that a lack of nitrogen changes the direction of carbon flow from protein synthesis to carbohydrate or lipid synthesis [86].”
BackgroundZhu, S., Qin, L., Feng, P., Shang, C., Wang, Z., & Yuan, Z. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.10.034 · Cited by 153 · see citing works
Self-citationZhang, J., Liu, L., & Chen, F. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.05.117 · Cited by 130 · see citing works
Mao, X., Wu, T., Sun, D., Zhang, Z., & Chen, F. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.10.090 · Cited by 116 · see citing works
Comparison of Growth Rate and Nutrient Content of Five Microalgae Species Cultivated in Greenhouses
Metsoviti, M. N., Papapolymerou, G., Karapanagiotidis, I. Τ., & Katsoulas, N. (2019) · Plants · doi:10.3390/plants8080279 · Cited by 87 · see citing works
Jiang, R., Qin, L., Feng, S., Huang, D., Wang, Z., & Zhu, S. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124690 · Cited by 84 · see citing works
Self-citationZhu, S., Wang, Y., Xu, J. H., Shang, C., Wang, Z., Xu, J., & Yuan, Z. (2015) · Bioresource Technology · doi:10.1016/j.biortech.2015.08.142 · Cited by 84 · see citing works
Self-citationZhu, S., Feng, S., Xu, Z., Qin, L., Shang, C., Feng, P., Wang, Z., & Yuan, Z. (2019) · Bioresource Technology · doi:10.1016/j.biortech.2019.121353 · Cited by 81 · see citing works
Self-citationMenegol, T., Diprat, A. B., Rodrigues, E., & Rech, R. (2017) · Food Science and Technology · doi:10.1590/1678-457x.13417 · Cited by 79 · see citing works
Xia, S., Gao, B., Fu, J., Xiong, J., & Zhang, C. (2018) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2018.06.002 · Cited by 72 · see citing works
Guo, L., Jin, Y., Xiao, Y., Tan, L., Tian, X., Ding, Y., He, K., Du, A., Li, J., Yi, Z., et al. (2019) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2019.119726 · Cited by 66 · see citing works
Grubišić, M., Šantek, B., Zorić, Z., Čošić, Z., Vrana, I., Gašparović, B., Čož‐Rakovac, R., & Šantek, M. I. (2022) · Molecules · doi:10.3390/molecules27041248 · Cited by 63 · see citing works
Pichrtová, M., Arc, E., Stöggl, W., Kranner, I., Hájek, T., Hackl, H., & Holzinger, A. (2016) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiw096 · Cited by 59 · see citing works
Physiological Changes of Parachlorella Kessleri TY02 in Lipid Accumulation under Nitrogen Stress
Gao, Y., Feng, J., Lv, J., Liu, Q., Nan, F., Liu, X., & Xie, S. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16071188 · Cited by 50 · see citing works
Zhang, Y., Wu, H., Yuan, C., Li, T., & Li, A. (2019) · Journal of Applied Phycology · doi:10.1007/s10811-019-01783-z · Cited by 47 · see citing works
Carbon starvation induces lipid degradation via autophagy in the model alga Micrasterias
Schwarz, V., Andosch, A., Geretschlaeger, A., Affenzeller, M., & Lütz‐Meindl, U. (2016) · Journal of Plant Physiology · doi:10.1016/j.jplph.2016.11.008 · Cited by 46 · see citing works
Proteome response of Dunaliella parva induced by nitrogen limitation
Shang, C., Zhu, S., Wang, Z., Qin, L., Alam, M. A., Xie, J., & Yuan, Z. (2017) · Algal Research · doi:10.1016/j.algal.2017.01.016 · Cited by 45 · see citing works
Self-citationFeng, S., Liu, F., Zhu, S., Feng, P., Wang, Z., Yuan, Z., Shang, C., & Chen, H. (2020) · Bioresource Technology · doi:10.1016/j.biortech.2020.123101 · Cited by 45 · see citing works
Self-citationReview on microalgae protein and its current and future utilisation in the food industry
Bhatnagar, P., Gururani, P., Singh, N., Gautam, P., Vlaskin, M. S., & Kumar, V. (2023) · International Journal of Food Science & Technology · doi:10.1111/ijfs.16586 · Cited by 43 · see citing works
Wang, F., Liu, T., Guan, W., Xu, L., Huo, S., Ma, A., Zhuang, G., & Terry, N. (2021) · Nanomaterials · doi:10.3390/nano11112802 · Cited by 41 · see citing works
The roles of starch and lipid in Chlorella sp. during cell recovery from nitrogen starvation
Zhu, S., Feng, P., Feng, J., Xu, J. H., Wang, Z., Xu, J., & Yuan, Z. (2017) · Bioresource Technology · doi:10.1016/j.biortech.2017.08.120 · Cited by 39 · see citing works
Self-citationWang, S., Sirbu, D., Thomsen, L., Kuhnert, N., Ullrich, M. S., & Thomsen, C. (2019) · Journal of Phycology · doi:10.1111/jpy.12887 · Cited by 37 · see citing works
Xu, Y., Falarz, L. J., & Chen, G. (2018) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.8b05755 · Cited by 34 · see citing works
Onay, M. (2020) · Fuel · doi:10.1016/j.fuel.2020.117795 · Cited by 34 · see citing works
Gorgich, M., Martins, A. A., Mata, T. M., & Caetano, N. S. (2021) · Algal Research · doi:10.1016/j.algal.2021.102508 · Cited by 32 · see citing works
Wang, S., Chunguang, Y., Yang, Z., Hu, X., Liu, Z., & Song, W. (2022) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2022.132939 · Cited by 31 · see citing works
Production of primary metabolites in Microcystis aeruginosa in regulation of nitrogen limitation
Zuo, Z., Ni, B., & Yang, L. (2018) · Bioresource Technology · doi:10.1016/j.biortech.2018.09.079 · Cited by 28 · see citing works
Zhang, J., He, Y., Luo, M., & Chen, F. (2019) · Algal Research · doi:10.1016/j.algal.2019.101730 · Cited by 27 · see citing works
Feng, S., Liu, F., Zhu, S., Xu, Z., Qin, L., Feng, P., Wang, Z., Chen, H., Guo, W., & Ngo, H. H. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.149538 · Cited by 24 · see citing works
Self-citationLima, S., Brucato, A., Caputo, G., Grisafi, F., & Scargiali, F. (2022) · Journal of Water Process Engineering · doi:10.1016/j.jwpe.2022.103142 · Cited by 24 · see citing works
Mixotrophic cultivation of Chromochloris zofingiensis on glycerol, acetate, and vinasse
Rahimi, M., & Jazini, M. (2021) · Journal of Applied Phycology · doi:10.1007/s10811-021-02568-z · Cited by 23 · see citing works
Progress towards a targeted biorefinery of Chromochloris zofingiensis: a review
Wood, E. E., Ross, M. E., Jubeau, S., Montalescot, V., & Stanley, M. S. (2022) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-022-02955-7 · Cited by 24 · see citing works
Zhang, Q., You, Z., & Miao, X. (2018) · Royal Society Open Science · doi:10.1098/rsos.181236 · Cited by 21 · see citing works
UV and γ-radiation induced molecular changes for rapid lipid accumulation in Chlorella sorokiniana
Singh, R. D., Sethy, S., Ghosh, S. B., & Srivastava, A. K. (2022) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2022.106493 · Cited by 20 · see citing works
Cosenza, A., Lima, S., Gurreri, L., Mancini, G., & Scargiali, F. (2024) · Algal Research · doi:10.1016/j.algal.2024.103669 · Cited by 20 · see citing works
Qi, F., Pei, H., Mu, R., Ma, G., Wu, D., & Han, Q. (2019) · Biotechnology for Biofuels · doi:10.1186/s13068-019-1493-9 · Cited by 20 · see citing works
Revealing dual roles of g-C3N4 in Chlorella vulgaris cultivation
Feng, Q., Sun, Y., Li, A., Lin, X., Lü, T., Ding, D., Shi, M., Sun, Y., & Yuan, Y. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127639 · Cited by 19 · see citing works
Li, Z., Yang, S., Zhou, Z., Peng, S., Zhang, Q., Long, H., & Li, H. (2021) · Biochemical Engineering Journal · doi:10.1016/j.bej.2021.108061 · Cited by 19 · see citing works
Qi, F., Pei, H., Ma, G., Zhang, S., & Mu, R. (2016) · Energy Conversion and Management · doi:10.1016/j.enconman.2016.10.022 · Cited by 19 · see citing works
Chen, C., & Chang, Y. (2018) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2018.01.008 · Cited by 19 · see citing works
Ghosh, A., Khanra, S., Mondal, M., Devi, T. I., Halder, G., Tiwari, O. N., Bhowmick, T. K., & Gayen, K. (2017) · Asia-Pacific Journal of Chemical Engineering · doi:10.1002/apj.2114 · Cited by 18 · see citing works
Structural Basis of Acyl-Carrier Protein Interactions in Fatty Acid and Polyketide Biosynthesis
Mindrebo, J. T., Patel, A., Misson, L., Kim, W. E., Davis, T. D., Ni, Q. Z., Clair, J. J. L., & Burkart, M. D. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-409547-2.14662-1 · Cited by 18 · see citing works
Bhowmick, G. D., Plouviez, M., Reis, M. G., Guieysse, B., Everett, D. W., Agnew, M. P., Maclean, P. H., & Thum, C. (2024) · ACS Omega · doi:10.1021/acsomega.4c00221 · Cited by 15 · see citing works
Stamenković, M., Steinwall, E., Nilsson, A., & Wulff, A. (2019) · Phytochemistry · doi:10.1016/j.phytochem.2019.112200 · Cited by 15 · see citing works
Wang, S., Zhao, Q., Yu, H., Du, X., Zhang, T., Sun, T., & Song, W. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1199472 · Cited by 14 · see citing works
Lu, L., Zhang, Y., & Yang, Y. (2022) · PLoS ONE · doi:10.1371/journal.pone.0273495 · Cited by 12 · see citing works
Magierek, E., & Krzemińska, I. (2018) · Phycologia · doi:10.2216/17-84.1 · Cited by 13 · see citing works
Koren, I., Boussiba, S., Khozin‐Goldberg, I., & Zarka, A. (2021) · Biology · doi:10.3390/biology10020157 · Cited by 13 · see citing works
Xu, Y., Pan, X., Lu, J., Wang, J., Shan, Q., Stout, J. M., & Chen, G. (2021) · Journal of Experimental Botany · doi:10.1093/jxb/erab236 · Cited by 12 · see citing works
The Lipidomic Analyses in Low and Highly Aggressive Ovarian Cancer Cell Lines
Zhao, Z., Cai, Q., & Xu, Y. (2015) · Lipids · doi:10.1007/s11745-015-4108-7 · Cited by 11 · see citing works
Microalgae as a source of alternative protein
Μάρκου, Γ., Chentir, I., Eliopoulos, C., Arapoglou, D., García‐Vaquero, M., & Tiwari, B. K. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99196-4.00036-x · Cited by 10 · see citing works
He, Q., Zhang, X., Xu, H., Wang, X., Zhang, X., Hao, Y., Song, X., & Cao, X. (2025) · Bioresource Technology · doi:10.1016/j.biortech.2025.132560 · Cited by 13 · see citing works
Wood, E. E., Ross, M. E., Jubeau, S., Montalescot, V., Mackechnie, K., Marchington, R. E., Davey, M. P., McNeill, S., Hamilton, C., & Stanley, M. S. (2023) · Algal Research · doi:10.1016/j.algal.2023.103238 · Cited by 11 · see citing works
Lima, S., Villanova, V., Grisafi, F., Brucato, A., & Scargiali, F. (2020) · The Canadian Journal of Chemical Engineering · doi:10.1002/cjce.23776 · Cited by 10 · see citing works
Papapanagiotou, G., Charisis, A., Samara, C., Kalogianni, E. P., & Chatzidoukas, C. (2024) · Processes · doi:10.3390/pr12122770 · Cited by 10 · see citing works
The effect of trehalose on the contents of starch and oil in microalga Dunaliella parva
Huang, L., Ruan, L., Guo, Y., Liang, X., & Shang, C. (2024) · Algal Research · doi:10.1016/j.algal.2024.103600 · Cited by 8 · see citing works
Self-citationArguelles, E. (2022) · Journal of Microbiology Biotechnology and Food Sciences · doi:10.55251/jmbfs.1931 · Cited by 7 · see citing works
Pitawala, S., Trifunovic, Z., Crosbie, N. D., Scales, P. J., & Martin, G. J. O. (2024) · Algal Research · doi:10.1016/j.algal.2024.103666 · Cited by 6 · see citing works
Ulya, S., Sedjati, S., & Yudiati, E. (2018) · BULETIN OSEANOGRAFI MARINA · doi:10.14710/buloma.v7i2.20109 · Cited by 5 · see citing works
Rao, X., Liang, W., Jing, X., Liu, C., Li, J., Liu, L., & Gao, X. (2025) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2025.06.004 · Cited by 4 · see citing works
Artificial produced water as a medium to grow Chlorella sp. for biodiesel production
Rakhmadumila, D. H., & Muntalif, B. S. (2020) · E3S Web of Conferences · doi:10.1051/e3sconf/202014802005 · Cited by 4 · see citing works
Myo-inositol as a carbon source in Chlorella sp. production
Erbil, G. Ç., Elp, M., & Durmaz, Y. (2024) · Bioresource Technology Reports · doi:10.1016/j.biteb.2024.101861 · Cited by 4 · see citing works
Responses of triacylglycerol synthesis in Skeletonema marinoi to nitrogen and phosphate starvations
Zhang, M., Xing, Y., Wang, F., Mi, T., & Zhen, Y. (2020) · Journal of Phycology · doi:10.1111/jpy.13044 · Cited by 5 · see citing works
Adekanmi, A. A., Garuba, E. O., Onilude, A. A., & Muraina, T. A. (2026) · Discover Sustainability · doi:10.1007/s43621-026-03910-6 · Cited by 4 · see citing works
Astaxanthin from Chromochloris zofingiensis: Feasibility analysis
Chen, J., Wei, D., Rao, A. R., & Ravishankar, G. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823304-7.00008-8 · Cited by 3 · see citing works
Applied Master of Renewable Energy Engineering, P. N. S., Hakim, L., & Rusdianasari, R. (2020) · Indonesian Journal of Fundamental and Applied Chemistry · doi:10.24845/ijfac.v6.i3.81 · Cited by 3 · see citing works
Yang, N., Shangguan, J., Zhang, L., Li, Y., Xu, J., Xia, X., & Liu, J. (2023) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2023.110174 · Cited by 3 · see citing works
Self-citationNiemi, C., & Gentili, F. G. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e33058 · Cited by 2 · see citing works
Sutherland, D. L., & Ralph, P. J. (2021) · Journal of Applied Phycology · doi:10.1007/s10811-021-02520-1 · Cited by 2 · see citing works
Lipid metabolism and metabolic engineering of eukaryotic microalgae
Zhang, Y., & Liu, J. (2021) · Advances in bioenergy · doi:10.1016/bs.aibe.2021.05.001 · Cited by 2 · see citing works
Chellamboli, C., Perumalsamy, M., & Sultan, M. A. (2024) · Environmental Science and Pollution Research · doi:10.1007/s11356-024-35261-y · Cited by 1 · see citing works
Gong, R., Li, C., Chen, B., Qiao, Z., Pan, Y., Men, J., Tan, L., Tian, S., Li, H., Li, Y., et al. (2025) · Journal of Food Biochemistry · doi:10.1155/jfbc/6667642 · Cited by 1 · see citing works
Gong, S., Zhang, Z., Su, Y., Huo, Y., Gao, M., Xu, Y., Wang, H., Zhang, S., & Sun, D. (2026) · Algal Research · doi:10.1016/j.algal.2026.104723 · Cited by 1 · see citing works
Biochemical engineering approaches to enhance the production of microalgae-based fuels
Dias, R. R., Sartori, R. B., Deprá, M. C., Lasta, P., & Maroneze, M. M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90971-6.00002-4 · Cited by 1 · see citing works
CONTEÚDO LIPÍDICO E PERFIL DE ÁCIDOS GRAXOS DE CHLORELLA VULGARIS CULTIVADA EM ÁGUA PRODUZIDA
Andrade, B. B., Cardoso, L. G., Mata, S. N., Silva, J. S. D. J., de Almeida, P. F., & Druzian, J. I. (2019) · doi:10.5151/siintec2019-103
Growth, Lipid, and Pigment Properties of Locally Isolated (Kastamonu, Türkiye) Chlorella sp.
Elp, M., Durmaz, Y., & Erbil, G. Ç. (2024) · Marine Science and Technology Bulletin · doi:10.33714/masteb.1443969
DpAGPs overexpression enhanced application value of Dunaliella Parva for bioethanol production
Huang, L., Zhang, J., Guo, Y., Liang, S., & Shang, C. (2026) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-025-04736-6
Self-citationNiyompanich, S., Kusolkumbot, P., Kunyalung, W., Watthammawut, A., & Powtongsook, S. (2026) · Life · doi:10.3390/life16050799
- Authors
- Zhu, S., Wang, Y., Shang, C., Wang, Z., Xu, J., & Yuan, Z.
- Affiliations
- Chinese Academy of Sciences (CN)
- Corresponding author
- Yuan, Zhenhong
- Venue
- Journal of Bioscience and Bioengineering
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 120
- Issue
- 2
- Pages
- 205-209
- ISSN
- 1347-4421 (ISSN-L)
- 1389-1723
- OpenAlex
- W2021707313
- Cited by
- 80
- References
- 35
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 10 · 2023: 6 · 2022: 8 · 2021: 12 · 2020: 6 · 2019: 13 · 2018: 8 · 2017: 5 · 2016: 3 · 2015: 2
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Bioscience and Bioengineering (publishedVersion)
- PubMed (publishedVersion)
- Institutional Repository of Guangzhou Institute of Energy Research, Chinese Academy of Sciences (submittedVersion)
- Funders
- National Natural Science Foundation of China (31100189)
- National Basic Research Program of China (2011CB200905)
- National Key Technology R&D Program of China (2011BAD14B03)
- National High-tech R&D Program (2013AA065803)
- Scientific Research Foundation
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Keywords
- Chlorella zofingiensis, nitrogen starvation, fatty acid composition, triglycerides, neutral lipids, glycolipids, phospholipids, oleic acid, monounsaturated fatty acids, polyunsaturated fatty acids, lipid quality, biodiesel feedstock
- MeSH terms
- Carbohydrates, Chlorella, Fatty Acids, Glycolipids, Lipids, Nitrogen, Phospholipids, Proteins, Triglycerides, Oleic Acid, Biofuels
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