The diagnosis of a smoking-related disease is a prominent trigger for smoking cessation in a retrospective cohort study
Abstract
Objective We evaluated the impact of demographic factors, smoking patterns, and the occurrence of smoking-related diseases on smoking cessation, with a particular emphasis on the temporal relationship between diagnosis of smoking-related diseases and cessation. Study design and setting A cohort was assembled of participants of a general health screening examination aged 50-74 years. Lifetime smoking habits and medical history were obtained by a self-administered questionnaire. In a retrospective cohort study approach, predictors of cessation among ever-smokers (n = 4,575) were identified using the extended proportional hazards model. Results Male gender, late onset of smoking, and higher educational level were predictive of cessation. However, the by far strongest predictors of cessation were diagnoses of smoking-related diseases: relative cessation rates in the year of disease occurrence were 11.2 for myocardial infarction (95% confidence interval CI = 8.9-14.0), 7.2 for stroke (95% CI = 5.1-11.6), 2.5 for diabetes mellitus (95% CI = 1.6-4.0) and 4.8 for cancer (95% CI = 3.1-7.4) relative to years before diagnosis of the respective diseases. Conclusion Our results underline the key role of perceived detrimental effects of smoking for cessation. When smokers personally experience the health consequences of smoking, many permanently quit.
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Individuals diagnosed with a smoking-related disease are more likely to quit smoking.
“A person diagnosed with a smoking-related disease is scientifically more likely to cease smoking (Twardella et al., 2006)”
From The Insula: A Brain Stimulation Target for the Treatment of Addiction (2019) · cites this paper as Twardella et al., 2006
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The Insula: A Brain Stimulation Target for the Treatment of Addiction
Ibrahim, C., Rubin-Kahana, D. S., Pushparaj, A., Musiol, M., Blumberger, D. M., Daskalakis, Z. J., Zangen, A., & Le Foll, B. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00720 · Cited by 133 · see citing works
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- Authors
- Twardella, D., Loew, M., Rothenbacher, D., Stegmaier, C., Ziegler, H., & Brenner, H.
- Affiliations
- Krebsregister Saarland (DE)
- Corresponding author
- Brenner, Hermann
- Venue
- Journal of Clinical Epidemiology
- Publisher
- Elsevier BV
- Published
- 2006-01
- Volume
- 59
- Issue
- 1
- Pages
- 82-89
- ISSN
- 0895-4356 (ISSN-L)
- OpenAlex
- W1999869147
- Cited by
- 133
- References
- 37
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 7 · 2022: 4 · 2021: 6 · 2020: 7 · 2019: 8 · 2018: 8 · 2017: 4 · 2016: 9 · 2015: 11 · 2014: 4 · 2013: 8 · 2012: 7
- FWCI
- 2.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Bundesministerium für Bildung und Forschung
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Keywords
- smoking cessation, smoking-related diseases, myocardial infarction, stroke, diabetes mellitus, cancer, predictors of quitting, ever-smokers, middle-aged and older adults, educational attainment, gender differences
- MeSH terms
- Age Factors, Aged, Diabetes Mellitus, Educational Status, Female, Humans, Male, Middle Aged, Myocardial Infarction, Neoplasms, Retrospective Studies, Sex Factors, Smoking, Smoking Cessation, Age of Onset, Stroke
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