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Cited by 351

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Relative to the general US population, chronic diseases are associated with poorer health-related quality of life as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS)

Open access
Rothrock, Nan E., Hays, Ron D., Spritzer, Karen, Yount, Susan E., Riley, William, Cella, David·2010·Journal of Clinical Epidemiology

Abstract

Objective The Patient-Reported Outcomes Measurement Information System (PROMIS) allows assessment of the impact of chronic conditions on health-related quality of life (HRQL) across diseases. We report on the HRQL impact of individual and comorbid conditions as well as conditions that are described as limiting activity. Study Design and Setting Data were collected through online and clinic recruitment as part of the PROMIS item calibration sample (n=21,133). Participants reported the presence or absence of 24 chronic health conditions and whether or not their activity was limited by each condition. Results Across health status domains, the presence of a chronic condition was associated with poorer scores than those without a diagnosis, particularly for those individuals who reported their condition was disabling. The magnitude of detriment in HRQL was more pronounced for individuals with two or more chronic conditions and could not be explained by sociodemographic factors. Patterns of HRQL deficits varied across disease and comorbidity status. Conclusion The impact of chronic conditions, particularly when experienced with comorbid disease, is associated with detriments in HRQL. The negative impact on HRQL varies across symptoms and functional areas within a given condition.

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Metadata

Authors
Rothrock, N. E., Hays, R. D., Spritzer, K., Yount, S. E., Riley, W., & Cella, D.
Venue
Journal of Clinical Epidemiology
Publisher
Elsevier BV
Published
2010-11
Volume
63
Issue
11
Pages
1195-1204
ISSN
0895-4356 (ISSN-L)
OpenAlex
W1965986657
Cited by
351
References
5
FWCI
8.60
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Relative to the general US population, chronic diseases are associated with poorer health-related quality of life as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS). https://app.cochat.ai/papers/10.1016/j.jclinepi.2010.04.012
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Rothrock, N. E., Hays, R. D., Spritzer, K., Yount, S. E., Riley, W., & Cella, D. (2010). Relative to the general US population, chronic diseases are associated with poorer health-related quality of life as measured by the Patient-Reported Outcomes Measurement Information System (PROMIS). Journal of Clinical Epidemiology. https://doi.org/10.1016/j.jclinepi.2010.04.012

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.