Cited by 331Advanced Drug Delivery SystemsNanoparticle-Based Drug DeliveryDrug Solubulity and Delivery Systems

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination

Garinot, Marie, Fiévez, Virginie, Pourcelle, Vincent, Stoffelbach, François, des Rieux, Anne, Plapied, Laurence, Theate, Ivan, Freichels, Hélène, Jérôme, Christine, Marchand-Brynaert, Jacqueline, Schneider, Yves-Jacques, Préat, Véronique·2007·Journal of Controlled Release

DOI 10.1016/j.jconrel.2007.04.021

Open this paper in CoChat — free account

Abstract

To improve the efficiency of orally delivered vaccines, PEGylated PLGA-based nanoparticles displaying RGD molecules at their surface were designed to target human M cells. RGD grafting was performed by an original method called "photografting" which covalently linked RGD peptides mainly on the PEG moiety of the PCL-PEG, included in the formulation. First, three non-targeted formulations with size and zeta potential adapted to M cell uptake and stable in gastro-intestinal fluids, were developed. Their transport by an in vitro model of the human Follicle associated epithelium (co-cultures) was largely increased as compared to mono-cultures (Caco-2 cells). RGD-labelling of nanoparticles significantly increased their transport by co-cultures, due to interactions between the RGD ligand and the beta(1) intregrins detected at the apical surface of co-cultures. In vivo studies demonstrated that RGD-labelled nanoparticles particularly concentrated in M cells. Finally, ovalbumin-loaded nanoparticles were orally administrated to mice and induced an IgG response, attesting antigen ability to elicit an immune response after oral delivery.

Integrity signals

Registry

Crossref · 10.1016/j.jconrel.2007.04.021

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Biodegradable Long-Circulating Polymeric Nanospheres
Gref, R., Minamitake, Y., Peracchia, M. T., Trubetskoy, V. S., Torchilin, V. P., & Langer, R. (1994) · Science · doi:10.1126/science.8128245 · Cited by 2,951
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
Rescigno, M., Urbano, M., Valzasina, B., Francolini, M., Rotta, G., Bonasio, R., Granucci, F., Kraehenbuhl, J.-P., & Ricciardi‐Castagnoli, P. (2001) · Nature Immunology · doi:10.1038/86373 · Cited by 2,554
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
des Rieux, A., Fievez, V., Garinot, M., Schneider, Y.-J., & Préat, V. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.08.013 · Cited by 1,305
Self-citation
Gastrointestinal Uptake of Biodegradable Microparticles: Effect of Particle Size
Desai, M. P., Labhasetwar, V. D., Amidon, G. L., & Levy, R. J. (1996) · Pharmaceutical Research · doi:10.1023/a:1016085108889 · Cited by 942
Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells
Artursson, P. (1990) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600790604 · Cited by 848
Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches
Eldridge, J. H., Hammond, C., Meulbroek, J. A., Staas, J. K., Gilley, R. M., & Tice, T. R. (1990) · Journal of Controlled Release · doi:10.1016/0168-3659(90)90133-e · Cited by 689
Reductive alkylation of amino groups in proteins
Means, G. E., & Feeney, R. E. (1968) · Biochemistry · doi:10.1021/bi00846a023 · Cited by 680
In vitro–in vivo correlations for lipophilic, poorly water-soluble drugs
Dressman, J., & Reppas, C. I. (2000) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(00)00181-0 · Cited by 586
Epithelial M Cells: Differentiation and Function
Kraehenbühl, J.-P., & Neutra, M. R. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.301 · Cited by 475
Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA) nanoparticles for controlled delivery of anticancer drugs
Dong, Y., & Feng, S. (2003) · Biomaterials · doi:10.1016/j.biomaterials.2003.09.055 · Cited by 472

Show all 37 references

Research works printed but not linked: 1

Pourcelle, 2007, PCL–PEG-based nanoparticles grafted with GRGDS peptide: surface analysis, J. Colloid. Interface Sci.

Sorted by citations

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
Makadia, H. K., & Siegel, S. J. (2011) · Polymers · doi:10.3390/polym3031377 · Cited by 4,816
“Therefore, the remaining gel becomes more hydrophobic in an aqueous environment, resulting in less water content [20,25–28].”
Background
PLGA-based nanoparticles: An overview of biomedical applications
Danhier, F., Ansorena, E., Silva, J. M., Coco, R., Breton, A. L., & Véronique Préat, A. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.01.043 · Cited by 4,006
Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
Nicolas, J., Mura, S., Brambilla, D., Mackiewicz, N., & Couvreur, P. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35265f · Cited by 1,270
pH-Responsive Nanoparticles for Drug Delivery
Gao, W., Chan, J. M., & Farokhzad, O. C. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100253e · Cited by 1,060
Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives
Mundargi, R. C., Babu, V. R., Rangaswamy, V., Patel, P., & Aminabhavi, T. M. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.09.013 · Cited by 1,025
Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications
Agarwal, S. V., Curtin, J. F., Duffy, B., & Jaiswal, S. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.06.020 · Cited by 973
Current advances in research and clinical applications of PLGA-based nanotechnology
Lü, J.-M., Wang, X., Marín‐Müller, C., Wang, H., Lin, P. H., Yao, Q. C., & Chen, C. (2009) · Expert Review of Molecular Diagnostics · doi:10.1586/erm.09.15 · Cited by 917
Paclitaxel-loaded PEGylated PLGA-based nanoparticles: In vitro and in vivo evaluation
Danhier, F., Lecouturier, N., Vroman, B., Jérôme, C., Marchand‐Brynaert, J., Féron, O., & Véronique Préat, A. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.09.086 · Cited by 617
Self-citation
The endocytosis and intracellular fate of nanomedicines: Implication for rational design
Kou, L., Sun, J., Zhai, Y., & He, Z. (2013) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2013.07.001 · Cited by 588
PLGA-Based Nanoparticles as Cancer Drug Delivery Systems
Mirakabad, F. S. T., Nejati‐Koshki, K., Akbarzadeh, A., Yamchi, M. R., Milani, M., Zarghami, N., Zeighamian, V., Rahimzadeh, A., Alimohammadi, S., Hanifehpour, Y., et al. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.2.517 · Cited by 553
Oral delivery of anticancer drugs: Challenges and opportunities
Thanki, K., Gangwal, R. P., Sangamwar, A. T., & Jain, S. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.04.020 · Cited by 510
Cancer Nanomedicine: From Drug Delivery to Imaging
Chow, E. K., & Ho, D. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3005872 · Cited by 503
Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents
Dinarvand, R., Sepehri, N., Manouchehri, Rouhani, & Atyabi, F. (2011) · International Journal of Nanomedicine · doi:10.2147/ijn.s18905 · Cited by 468
Recent advances in chitosan-based nanoparticles for oral delivery of macromolecules
Chen, M., Mi, F., Liao, Z., Hsiao, C., Sonaje, K., Chung, M., Hsu, L., & Sung, H. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.010 · Cited by 453
pH-Responsive carriers for oral drug delivery: Challenges and opportunities of current platforms
Liu, L., Yao, W., Rao, Y., Lu, X., & Gao, J. (2017) · Drug Delivery · doi:10.1080/10717544.2017.1279238 · Cited by 420
Current state and challenges in developing oral vaccines
Ramirez, J. E. V., Sharpe, L. A., & Peppas, N. A. (2017) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2017.04.008 · Cited by 425
Recent progress in biomedical applications of pluronic (PF127): Pharmaceutical perspectives
Akash, M. S. H., & Rehman, K. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.04.032 · Cited by 394
Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics
Ding, D., & Zhu, Q. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2017.12.036 · Cited by 394
Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Zhu, Q., Chen, Z., Paul, P. K., Lü, Y., Wu, W., & Qi, J. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.04.001 · Cited by 366
PLGA-Based Composites for Various Biomedical Applications
Rocha, C. V., Gonçalves, V., da Silva, M. C., Bañobre‐López, M., & Gallo, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042034 · Cited by 379
PLGA-based nanoparticles: A new paradigm in biomedical applications
Sharma, S., Parmar, A., Kori, S., & Sandhir, R. (2015) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2015.06.014 · Cited by 350
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with Paclitaxel
Danhier, F., Vroman, B., Lecouturier, N., Crokart, N., Pourcelle, V., Freichels, H., Jérôme, C., Marchand‐Brynaert, J., Féron, O., & Véronique Préat, A. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.08.011 · Cited by 335
Self-citation
M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis
Corr, S. C., Gahan, C. C. G. M., & Hill, C. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2007.00359.x · Cited by 320
Biopharmaceutical Parameters to Consider in Order to Alter The Fate of Nanocarriers After Oral Delivery
Roger, E., Lagarce, F., Garcion, E., & Benoît, J. (2010) · Nanomedicine · doi:10.2217/nnm.09.110 · Cited by 332
Fate of polymeric nanocarriers for oral drug delivery
Plapied, L., Duhem, N., Rieux, A. D., & Véronique Préat, A. (2011) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2010.12.005 · Cited by 320
Self-citation
Nanotechnology: an effective tool for enhancing bioavailability and bioactivity of phytomedicine
Gunasekaran, T., Haile, T., Nigusse, T., & Dhanaraju, M. D. (2014) · Asian Pacific Journal of Tropical Biomedicine · doi:10.12980/apjtb.4.2014c980 · Cited by 317
Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations
Hamdy, S. I., Haddadi, A., Hung, R., & Lavasanifar, A. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.05.021 · Cited by 301
Folic acid–Pluronic F127 magnetic nanoparticle clusters for combined targeting, diagnosis, and therapy applications
Lin, J.-J., Chen, J., Huang, S., Ko, J.-H., Wang, Y., Chen, T.-L., & Wang, L. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.06.004 · Cited by 266
Nanoparticles and microparticles as vaccine-delivery systems
Singh, M., Chakrapani, A., & O’Hagan, D. T. (2007) · Expert Review of Vaccines · doi:10.1586/14760584.6.5.797 · Cited by 259
PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity
Silva, A. L., Soema, P. C., Slütter, B., OSSENDORP, F. A., & Jiskoot, W. (2016) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1117714 · Cited by 256
Recent Advances in Drug Delivery Systems
Martinho, N., Damgé, C., & Reis, C. P. (2011) · Journal of Biomaterials and Nanobiotechnology · doi:10.4236/jbnb.2011.225062 · Cited by 248
Aerosolized PLA and PLGA Nanoparticles Enhance Humoral, Mucosal and Cytokine Responses to Hepatitis B Vaccine
Thomas, C., Rawat, A. K., Hope‐Weeks, L. J., & Ahsan, F. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100255c · Cited by 241
Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapy
Schleich, N., Po, C., Jacobs, D., Ucakar, B., Gallez, B., Danhier, F., & Préat, V. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.07.059 · Cited by 238
Chitosan-based nanoparticles: An overview of biomedical applications and its preparation
Naskar, S., Sharma, S., & Kuotsu, K. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.10.022 · Cited by 238
Peptide/protein vaccine delivery system based on PLGA particles
Allahyari, M., & Mohit, E. (2015) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1102804 · Cited by 234
The challenges of oral drug delivery via nanocarriers
Reinholz, J., Landfester, K., & Mailänder, V. (2018) · Drug Delivery · doi:10.1080/10717544.2018.1501119 · Cited by 237
Immune system targeting by biodegradable nanoparticles for cancer vaccines
Silva, J. M., Videira, M., Gaspar, R. S., Véronique Préat, A., & Florindo, H. F. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.03.010 · Cited by 240
Gum-based nanocarriers for the protection and delivery of food bioactive compounds
Taheri, A., & Jafari, S. M. (2019) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2019.04.009 · Cited by 217
Dual anticancer drug/superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging
Schleich, N., Sibret, P., Danhier, P., Učakar, B., Laurent, S., Müller, R. N., Jérôme, C., Gallez, B., Véronique Préat, A., & Danhier, F. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.02.042 · Cited by 225
Self-citation
Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems
Xu, Y., Shrestha, N., Véronique Préat, A., & Beloqui, A. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.04.006 · Cited by 219
Cationic Polymer Nanoparticles and Nanogels: From Synthesis to Biotechnological Applications
Ramos, J., Forcada, J., & Hidalgo-Álvarez, R. (2013) · Chemical Reviews · doi:10.1021/cr3002643 · Cited by 202
M Cells: Intelligent Engineering of Mucosal Immune Surveillance
Dillon, A., & Lo, D. D. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.01499 · Cited by 194
Mucoadhesive carriers for oral drug delivery
Kumar, R., Islam, T., & Nurunnabi, M. (2022) · Journal of Controlled Release · doi:10.1016/j.jconrel.2022.09.024 · Cited by 212
Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination
Slütter, B., Plapied, L., Fievez, V., Alonso, M. J., Rieux, A. D., Schneider, Y., van Riet, E., Jiskoot, W., & Véronique Préat, A. (2009) · Journal of Controlled Release · doi:10.1016/j.jconrel.2009.05.011 · Cited by 192
Self-citation
Drug delivery to inflamed colon by nanoparticles: Comparison of different strategies
Coco, R., Plapied, L., Pourcelle, V., Jérôme, C., Brayden, D. J., Schneider, Y.-J., & Préat, V. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.07.017 · Cited by 162
Self-citation
Mucosal vaccines: Strategies and challenges
Li, M., Wang, Y., Sun, Y., Cui, H., Zhu, S., & Qiu, H. (2019) · Immunology Letters · doi:10.1016/j.imlet.2019.10.013 · Cited by 186
An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers
Xu, Y., Shrestha, N., Véronique Préat, A., & Beloqui, A. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.05.005 · Cited by 192
Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome
Lee, Y., Kamada, N., & Moon, J. J. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.114021 · Cited by 169
Antibody-Targeted Nanoparticles for Cancer Therapy
Fay, F., & Scott, C. J. (2011) · Immunotherapy · doi:10.2217/imt.11.5 · Cited by 165
Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination
Fiévez, V., Plapied, L., Rieux, A. D., Pourcelle, V., Freichels, H., Wascotte, V., Vanderhaeghen, M.-L., Jérôme, C., Vanderplasschen, A. F. C., Marchand‐Brynaert, J., et al. (2009) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2009.04.009 · Cited by 158
Self-citation
LyP-1-conjugated nanoparticles for targeting drug delivery to lymphatic metastatic tumors
Luo, G., Yu, X., Jin, C., Yang, F., Fu, D., Long, J., Xu, J., Zhan, C., & Lu, W. (2009) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2009.10.014 · Cited by 160
Oral delivery of nanoparticle-based vaccines
Marasini, N., Skwarczyński, M., & Tóth, I. (2014) · Expert Review of Vaccines · doi:10.1586/14760584.2014.936852 · Cited by 157
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
Sureban, S. M., May, R. J., Mondalek, F. G., Qu, D., Ponnurangam, S., Pantazis, P., Anant, S., Ramanujam, R. P., & Houchen, C. W. (2011) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-9-40 · Cited by 153
Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies
Wang, S., Liu, H., Zhang, X., & Qian, F. (2015) · Protein & Cell · doi:10.1007/s13238-015-0164-2 · Cited by 157
Application of nanotechnologies for improved immune response against infectious diseases in the developing world
Look, M., Bandyopadhyay, A., Blum, J. S., & Fahmy, T. M. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.011 · Cited by 152
Targeted delivery of chitosan nanoparticles to Peyer’s patch using M cell-homing peptide selected by phage display technique
Yoo, M. K., Kang, S., Choi, J.-H., Park, I., Na, H. S., Lee, H., Kim, E.-B., Lee, N.-K., Nah, J., Choi, Y.-J., et al. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.06.059 · Cited by 150
PLGA-based nanoparticles for the treatment of cancer: current strategies and perspectives
Alvi, M., Yaqoob, A., Rehman, K., Shoaib, S. M., & Akash, M. S. H. (2022) · AAPS Open · doi:10.1186/s41120-022-00060-7 · Cited by 161
Targeted nanoparticles with novel non-peptidic ligands for oral delivery
Rieux, A. D., Pourcelle, V., Cani, P. D., Marchand‐Brynaert, J., & Véronique Préat, A. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.01.002 · Cited by 149
Self-citation
Is nanotechnology a boon for oral drug delivery?
Agrawal, U., Sharma, R. K., Gupta, M., & Vyas, S. P. (2014) · Drug Discovery Today · doi:10.1016/j.drudis.2014.04.011 · Cited by 149
In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model
Silva, J. M., Zupančič, E., Vandermeulen, G., Oliveira, V. G., Salgado, A., Videira, M., Gaspar, M. M., Graça, L., Véronique Préat, A., & Florindo, H. F. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2014.11.033 · Cited by 146
Recent advances in nanocarrier-based mucosal delivery of biomolecules
Kammona, O., & Kiparissides, C. A. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.05.040 · Cited by 142
The intelligent delivery systems for bioactive compounds in foods: Physicochemical and physiological conditions, absorption mechanisms, obstacles and responsive strategies
Chai, J., Jiang, P., Wang, P., Jiang, Y., Li, D., Bao, W., Liu, B., Liu, B., Zhao, L., Norde, W., et al. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.06.003 · Cited by 142
Nanoparticle Systems for Cancer Vaccine
Wen, R. M., Umeano, A. C., Kou, Y., Xu, J., & Farooqı, A. A. (2019) · Nanomedicine · doi:10.2217/nnm-2018-0147 · Cited by 140
Research on the fate of polymeric nanoparticles in the process of the intestinal absorption based on model nanoparticles with various characteristics: size, surface charge and pro-hydrophobics
Guo, S., Liang, Y., Liu, L., Yin, M., Wang, A., Sun, K., Li, Y., & Shi, Y. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-00770-2 · Cited by 135
Transepithelial transport of nanoparticles in oral drug delivery: From the perspective of surface and holistic property modulation
Zheng, Y., Luo, S., Xu, M., He, Q., Xie, J., Wu, J., & Huang, Y. (2024) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2024.06.015 · Cited by 140
Recent developments in nanoparticle-based drug delivery and targeting systems with emphasis on protein-based nanoparticles
Wang, G., & Uludağ, H. (2008) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.5.5.499 · Cited by 127
Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier
Beloqui, A., Rieux, A. D., & Véronique Préat, A. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.04.014 · Cited by 131
Intestinal delivery of non-viral gene therapeutics: physiological barriers and preclinical models
O’Neill, M. J., Bourré, L., Melgar, S., & O’Driscoll, C. M. (2011) · Drug Discovery Today · doi:10.1016/j.drudis.2011.01.003 · Cited by 128
Vaccine delivery carriers: Insights and future perspectives
Correia‐Pinto, J., Csaba, N., & Alonso, M. J. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.04.047 · Cited by 122
Ionic liquids for the preparation of biopolymer materials for drug/gene delivery: a review
Chen, J., Xie, F., Li, X., & Chen, L. (2018) · Green Chemistry · doi:10.1039/c8gc01120f · Cited by 125
Lactoferrin functionalized PEG-PLGA nanoparticles of shikonin for brain targeting therapy of glioma
Li, H., Tong, Y., Bai, L., Ye, L., Zhong, L., Duan, X., & Zhu, Y. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.08.155 · Cited by 122
Poly(Lactic Acid) and Poly(Lactic- Co -Glycolic Acid) Particles as Versatile Carrier Platforms for Vaccine Delivery
Pavot, V., Berthet, M., Rességuier, J., Legaz, S., Handké, N., Gilbert, S. C., Paul, S., & Verrier, B. (2014) · Nanomedicine · doi:10.2217/nnm.14.156 · Cited by 115
Targeting the intestinal lymphatic system: a versatile path for enhanced oral bioavailability of drugs
Managuli, R. S., Raut, S. Y., Reddy, M. S., & Mutalik, S. (2018) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2018.1503249 · Cited by 113
Traffic of poly(lactic acid) nanoparticulate vaccine vehicle from intestinal mucus to sub-epithelial immune competent cells
Primard, C., Rochereau, N., Luciani, E., Genin, C., Delair, T., Paul, S., & Verrier, B. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.04.021 · Cited by 112
Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine
Bershteyn, A., Hanson, M. C., Crespo, M. P., Moon, J. J., Li, A. V., Suh, H., & Irvine, D. J. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.029 · Cited by 109
Transport of chitosan–DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes
Kadiyala, I., Loo, Y., Roy, K., Rice, J., & Leong, K. W. (2009) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2009.11.002 · Cited by 109
Multifunctional nanoparticle developments in cancer diagnosis and treatment
Parvanian, S., Mostafavi, S. M., & Aghashiri, M. (2016) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2016.08.002 · Cited by 109
PEG–PLA–PEG block copolymeric nanoparticles for oral immunization against hepatitis B
Jain, A., Goyal, A. K., Mishra, N., Vaidya, B., Mangal, S., & Vyas, S. P. (2009) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2009.12.013 · Cited by 108
Immunoadjuvant capacity of flagellin and mannosamine-coated poly(anhydride) nanoparticles in oral vaccination
Salman, H. H., Irache, J. M., & Gamazo, C. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.05.091 · Cited by 107
Interactions between Nanoparticles and Intestine
Vitulo, M., Gnodi, E., Meneveri, R., & Barisani, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084339 · Cited by 112
Rational design of nanoparticles towards targeting antigen-presenting cells and improved T cell priming
Zupančič, E., Curato, C., Paisana, M. C., Rodrigues, C. A. B., Porat, Z., Viana, A. S., Afonso, C. A. M., Pinto, J. F., Gaspar, R. S., Moreira, J. N., et al. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.05.014 · Cited by 107
Gemcitabine and betulinic acid co-encapsulated PLGA−PEG polymer nanoparticles for improved efficacy of cancer chemotherapy
Saneja, A., Kumar, R., Mintoo, M. J., Dubey, R. D., Sangwan, P. L., Mondhe, D. M., Panda, A. K., & Gupta, P. N. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.01.026 · Cited by 104
T7 Peptide-Functionalized PEG-PLGA Micelles Loaded with Carmustine for Targeting Therapy of Glioma
Bi, Y., Liu, L., Lü, Y., Sun, T., Shen, C., Chen, X., Chen, Q., An, S., He, X., Ruan, C., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b05572 · Cited by 105
Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats
Radwan, M. A., AlQuadeib, B. T., Šiller, L., Wright, M. C., & Horrocks, B. R. (2017) · Drug Delivery · doi:10.1080/10717544.2016.1228715 · Cited by 103
A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation
Beloqui, A., Brayden, D. J., Artursson, P., Véronique Préat, A., & Rieux, A. D. (2017) · Nature Protocols · doi:10.1038/nprot.2017.041 · Cited by 100
Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma
Ganipineni, L. P., Učakar, B., Joudiou, N., Bianco, J. I., Danhier, P., Zhao, M., Bastiancich, C., Gallez, B., Danhier, F., & Véronique Préat, A. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s165184 · Cited by 100
Nanoparticle transport across in vitro olfactory cell monolayers
Gartziandia, O., Egusquiaguirre, S. P., Bianco, J. I., Pedraz, J. L., Igartúa, M., Hernández, R. M., Véronique Préat, A., & Beloqui, A. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.12.046 · Cited by 97
Mucosal vaccine delivery: A focus on the breakthrough of specific barriers
Huang, M., Zhang, M., Zhu, H., Du, X., & Wang, J. (2022) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2022.07.002 · Cited by 96
Studies on stabilization mechanism and stealth effect of poloxamer 188 onto PLGA nanoparticles
Jain, D. S., Athawale, R., Bajaj, A., Shrikhande, S. S., Goel, P. N., & Gude, R. P. (2013) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2013.03.027 · Cited by 94
Nanoparticles as Protein and Gene Carriers to Mucosal Surfaces
de la Fuente, M., Csaba, N., García-Fuentes, M., & Alonso, M. J. (2008) · Nanomedicine · doi:10.2217/17435889.3.6.845 · Cited by 93
Crossing the barrier: Targeting epithelial receptors for enhanced oral vaccine delivery
Devriendt, B., Geest, B. G. D., Goddeeris, B. M., & Cox, E. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.02.006 · Cited by 94
Polymer nanotechnology based approaches in mucosal vaccine delivery: Challenges and opportunities
Sharma, R. K., Agrawal, U., Mody, N., & Vyas, S. P. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2014.12.004 · Cited by 91
Temperature-responsive polymeric nanospheres containing methotrexate and gold nanoparticles: A multi-drug system for theranostic in rheumatoid arthritis
Lima, S. A. C., & Reis, S. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.04.048 · Cited by 90
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method
Corbet, C., Ragelle, H., Pourcelle, V., Vanvarenberg, K., Marchand‐Brynaert, J., Véronique Préat, A., & Féron, O. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.12.020 · Cited by 87
Self-citation
Engineering Nano‐ and Microparticles as Oral Delivery Vehicles to Promote Intestinal Lymphatic Drug Transport
Miao, Y., Lin, Y., Chen, K., Luo, P.-K., Chuang, S., Yu, Y., Tai, H., Chen, C., Lin, K., & Sung, H. (2021) · Advanced Materials · doi:10.1002/adma.202104139 · Cited by 87
Design Opportunities for Actively Targeted Nanoparticle Vaccines
Fahmy, T. M., Demento, S. L., Caplan, M. J., Mellman, I., & Saltzman, W. M. (2008) · Nanomedicine · doi:10.2217/17435889.3.3.343 · Cited by 86
Therapeutic applications of betulinic acid nanoformulations
Saneja, A., Arora, D., Kumar, R., Dubey, R. D., Panda, A. K., & Gupta, P. N. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13570 · Cited by 84
Chitosan-coated poly(lactic-co-glycolic) acid nanoparticles as an efficient delivery system for Newcastle disease virus DNA vaccine
Zhao, K., Zhang, Y., Wang, X., Shi, C., Wang, X., Wang, X., Jin, Z., & Cui, S. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s70633 · Cited by 84
PLGA Particles in Immunotherapy
Horvath, D. J., & Basler, M. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15020615 · Cited by 88
Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1
Gao, Y., Wijewardhana, C. N., & Mann, J. F. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00345 · Cited by 80

Authors: Garinot, M., Fiévez, V., Pourcelle, V., Stoffelbach, F., des Rieux, A., Plapied, L., Theate, I., Freichels, H., Jérôme, C., Marchand-Brynaert, J., Schneider, Y.-J., & Préat, V.
Affiliations: UCLouvain (BE)
University of Liège (BE)
ORCID: Stoffelbach, François
Jérôme, Christine
Schneider, Yves-Jacques
Venue: Journal of Controlled Release
Publisher: Elsevier BV
Published: 2007-07
Volume: 120
Issue: 3
Pages: 195-204
ISSN: 0168-3659 (ISSN-L)
DOI: 10.1016/j.jconrel.2007.04.021
OpenAlex: W1982938211
Cited by: 331
References: 37
Citations by year: 2026: 7 · 2025: 7 · 2024: 9 · 2023: 12 · 2022: 17 · 2021: 15 · 2020: 23 · 2019: 19 · 2018: 26 · 2017: 20 · 2016: 24 · 2015: 22 · 2014: 21 · 2013: 21 · 2012: 23
FWCI: 11.92
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Controlled Release (publishedVersion)
PubMed (publishedVersion)
Digital Access to Libraries (submittedVersion)
Open Repository and Bibliography (University of Liège) (submittedVersion)
Topics: Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Drug Solubulity and Delivery Systems
Keywords: oral immunization, M cells, RGD peptide, photografting, follicle-associated epithelium, nanoparticle uptake, ovalbumin, IgG antibody response, oral vaccine delivery
MeSH terms: Polylactic Acid-Polyglycolic Acid Copolymer, Administration, Oral, Animals, Epithelial Cells, Female, Ovarian Follicle, Humans, Immunization, Secondary, Injections, Intramuscular, Intestinal Mucosa, Mice, Inbred Strains, Oligopeptides, Ovalbumin, Peyer's Patches, Polyethylene Glycols, Polyglycolic Acid, Polymers, Vaccination, Fluorescein-5-isothiocyanate, Coculture Techniques, Caco-2 Cells, Integrin beta1, Lactic Acid, Integrin alpha5beta1, Cell Line, Tumor, Mice, Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks