The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery
Abstract
Injectable in situ thermosensitive hydrogels have potential applications in tissue engineering and drug delivery. The hydrogel formulations exist as aqueous solutions at room temperature but rapidly solidify into gels at 37 °C in situ, making them highly suitable for administering drugs in a minimally invasive manner to the target organ(s). The hydrogel formed with nanoparticles assembled with amphiphilic polymer blocks of polyethyleneglycol (PEG) and biodegradable polycaprolactone (PCL) have been tested as platforms for targeted and sustained drug delivery, and have shown encouraging results. In this review, we summarize the influence of the molecular weight, PEG/PCL ratio and functional structure of hydrophobic PCL blocks on the critical gelation temperature, gelling behavior and drug release kinetics of the hydrogels. The current studies on the biomedical applications of thermosensitive PEG/PCL hydrogels have also been discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hydrogels for biomedical applications
Hoffman, A. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00239-3 · Cited by 4,864
Hydrogels for biomedical applications
Hoffman, A. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.010 · Cited by 3,396
Thermally induced association and dissociation of methylcellulose in aqueous solutions
Li, L., Shan, H., Yue, C. Y., Lam, Y. C., Tam, K. C., & Hu, X. (2002) · Langmuir · doi:10.1021/la020029b · Cited by 247
Cited by
Ilyas, R., Zuhri, M., Norrrahim, M., Misenan, M., Jenol, M., Samsudin, S., Nurazzi, N., Asyraf, M., Supian, A., Bangar, S., et al. (2022) · Polymers · doi:10.3390/polym14010182 · Cited by 268
Biomaterials / bioinks and extrusion bioprinting
Chen, X. B., Fazel Anvari-Yazdi, A., Duan, X., Zimmerling, A., Gharraei, R., Sharma, N. K., Sweilem, S., & Ning, L. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.06.006 · Cited by 244
Self-citationResorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98
Zhang, W., Taheri-Ledari, R., Ganjali, F., Afruzi, F. H., Hajizadeh, Z., Saeidirad, M., Qazi, F. S., Kashtiaray, A., Sehat, S. S., Hamblin, M. R., et al. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09577 · Cited by 79
RetractedLuo, Y., Li, J., Hu, Y., Gao, F., Pak-Heng Leung, G., Geng, F., Fu, C., & Zhang, J. (2020) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2020.05.011 · Cited by 72
Metadata
- Authors
- Deng, H., Dong, A., Song, J., & Chen, X.
- Venue
- Journal of Controlled Release
- Publisher
- Elsevier BV
- Published
- 2019-03
- Volume
- 297
- Pages
- 60-70
- ISSN
- 0168-3659 (ISSN-L)
- OpenAlex
- W2915061266
- Cited by
- 181
- References
- 3
- FWCI
- 5.59
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery. https://app.cochat.ai/papers/10.1016/j.jconrel.2019.01.026
- The paper
- Deng, H., Dong, A., Song, J., & Chen, X. (2019). Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery. Journal of Controlled Release. https://doi.org/10.1016/j.jconrel.2019.01.026
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
