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Cited by 286

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk

Open access
Martins-Mendes, Daniela, Monteiro-Soares, Matilde, Boyko, Edward John, Ribeiro, Manuela, Barata, Pedro, Lima, Jorge, Soares, Raquel·2014·Journal of Diabetes and its Complications

Abstract

Aims To estimate 3-year risk for diabetic foot ulcer (DFU), lower extremity amputation (LEA) and death; determine predictive variables and assess derived models accuracy. Material and Methods Retrospective cohort study including all subjects with diabetes enrolled in our diabetic foot outpatient clinic from beginning 2002 until middle 2010. Data was collected from clinical records. Results 644 subjects with mean age of 65.1 (±11.2) and diabetes duration of 16.1 (±10.8) years. Cumulative incidence was 26.6% for DFU, 5.8% for LEA and 14.0% for death. In multivariate analysis, physical impairment, peripheral arterial disease complication history, complication count and previous DFU were associated with DFU; complication count, foot pulses and previous DFU with LEA and age, complication count and previous DFU with death. Predictive models’ areas under the ROC curves from 0.80 to 0.83. A simplified model including previous DFU and complication count presented high accuracy. Previous DFU was associated with all outcomes, even when adjusted for complication count, in addition to more complex models. Conclusions DFU seems more than a marker of complication status, having independent impact on LEA and mortality risk. Proposed models may be applicable in healthcare settings to identify patients at higher risk of DFU, LEA and death.

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Metadata

Authors
Martins-Mendes, D., Monteiro-Soares, M., Boyko, E. J., Ribeiro, M., Barata, P., Lima, J., & Soares, R.
Venue
Journal of Diabetes and its Complications
Publisher
Elsevier BV
Published
2014-09
Volume
28
Issue
5
Pages
632-638
ISSN
  • 0891-6632 (ISSN-L)
  • 1056-8727
OpenAlex
W2091286023
Cited by
286
References
28
FWCI
12.21
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. https://app.cochat.ai/papers/10.1016/j.jdiacomp.2014.04.011
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Martins-Mendes, D., Monteiro-Soares, M., Boyko, E. J., Ribeiro, M., Barata, P., Lima, J., & Soares, R. (2014). The independent contribution of diabetic foot ulcer on lower extremity amputation and mortality risk. Journal of Diabetes and its Complications. https://doi.org/10.1016/j.jdiacomp.2014.04.011

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.