Low prevalence of atrial fibrillation in community-dwelling Chinese aged 55 years or older in Singapore: a population-based study
Abstract
Background The prevalence of atrial fibrillation (AF) in Asian populations appears to be lower than that in Western populations according to limited data. We conducted a community study to (a) estimate the prevalence of AF in Chinese adults aged 55 years or older in Singapore and (b) examine associated risk factors.Methods We conducted a whole-survey area population screening of 1839 Chinese residents aged 55 years or older in the southeast region of Singapore with a single electrocardiographic recording. We performed structured interviews and anthropometric as well as clinical measurements, including blood pressure.Results The estimated overall AF prevalence was 1.5% (95% confidence interval = 1.1-2.2); specifically, the prevalence was higher in men (2.6%) than in women (0.6%) and increased sharply to 5.8% only in individuals aged 80 years or older. This latter rate is lower than age-standardized rates in Western populations by approximately half and consistent with similarly low prevalence rates reported for Korea and China. Of the 26 cases of AF in this study, only 10 were known cases; 3 of the 10 patients were receiving anticoagulant therapy, whereas the rest were receiving antiplatelet therapy. Atrial fibrillation was significantly associated in multivariate analyses with male sex (odds ratio [OR] = 4.10), heart failure (OR = 3.11), and stroke (OR = 3.60).Conclusions These data add support to the view that the prevalence of AF in Asian populations is lower than that in Western populations. The observations from these contrasting populations warrant attention in future studies.
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The overall prevalence of AF varies by ancestry.
“The overall prevalence of AF varies by ancestry; prevalence studies of Asian populations have been less consistent than those of North American and European poulations.”
From Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis (2016) · cites this paper as [23]
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- Authors
- Yap, K. B., Ng, T. P., & Ong, H. Y.
- Affiliations
- National University of Singapore (SG)
- Alexandra Hospital (SG)
- Corresponding author
- Yap, Keng Bee
- Venue
- Journal of Electrocardiology
- Publisher
- Elsevier BV
- Published
- 2008-03
- Volume
- 41
- Issue
- 2
- Pages
- 94-98
- ISSN
- 0022-0736 (ISSN-L)
- OpenAlex
- W2062625526
- Cited by
- 84
- References
- 35
- Citations by year
- 2026: 3 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 4 · 2020: 2 · 2019: 5 · 2018: 10 · 2017: 6 · 2016: 9 · 2015: 9 · 2014: 7 · 2013: 4 · 2012: 5
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Electrocardiology (publishedVersion)
- PubMed (publishedVersion)
- National University of Singapore (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cardiovascular and Diving-Related Complications
- Keywords
- atrial fibrillation, prevalence, Chinese older adults, Asian populations, sex differences, heart failure, stroke, risk factors, anticoagulation, antiplatelet therapy, Singapore
- MeSH terms
- Aged, Aged, 80 and over, Atrial Fibrillation, Electrocardiography, Female, Humans, Male, Middle Aged, Risk Factors, Singapore, Prevalence, Risk Assessment, Asian People
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