Continuous heart rhythm monitoring using mobile photoplethysmography in ambulatory patients
Abstract
Background Wearable devices using photo-plethysmography (PPG) can accurately detect heart beats and may be useful for heart rate measurement and diagnosis of arrhythmias such as atrial fibrillation (AF). A previous study of a new portable PPG sensor (CardiacSense) showed high accuracy in heart rate measurement and AF detection in resting patients. We report a trial done to test the same device in active ambulatory patients with diverse characteristics.Methods A cohort of 24 ambulatory volunteers, underwent simultaneous PPG recording and continuous electrocardiogram (ECG) recording under different environmental conditions and situations. Per study protocol, the subjects were diverse in age, BMI, hair density and skin tone. Four subjects had AF. Heart rate measurement using the PPG device was compared to measurements by ECG.Results Of 163,527 recorded ECG-detected beats in the trial, 86,929 (53.2%) were also recorded by the PPG device. Most undetected heart beats were due to motion induced noise. Correlation between ECG and PPG was high (R = 0.94, p < 0.0001), yet in subjects with AF correlation was lower (R = 0.80, p < 0.0001). A Bland-Altman analysis showed the mean difference between measurements was -0.7 ms (95% limit of agreement -93.8 to 92.2). A total of 86,217 (99.9%) of all RR measurements were reliably measured (RR difference within 100 ms). Reliability was sustained (>99.8%) in subjects of all groups including subjects with AF.Conclusions This study showed that, in the absence of movement-related noise, the CardiacSense PPG device can reliably detect HR in a variety of situations and subjects' characteristics.
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Four of the ten included studies reported statistically significant reductions in heart rate measurement accuracy in participants with darker skin tones compared to participants with lighter skin tones.
“Overall, four of the ten studies reported a significant reduction in accuracy of heart rate measurement with wearable devices in darker-skinned individuals, compared to participants with lighter skin tones.”
From Accuracy of heart rate measurement with wrist-worn wearable devices in various skin tones: a systematic review (2023) · cites this paper as [3]
Hemoglobin in dermal blood vessels drives the bulk of light absorption, and changes in blood pressure and flow rate affect light absorption, which is detected by PPG optical sensors.
“Hemoglobin in dermal blood vessels drives the bulk of light absorption, and thus changes in blood pressure and flow rate affect light absorption, which is then detected by PPG optical sensors [2, 3].”
From Accuracy of heart rate measurement with wrist-worn wearable devices in various skin tones: a systematic review (2023) · cites this paper as [3]
Hochstadt et al. noted a linear regression coefficient of 0.98 (p < 0.001) when comparing PPG to ECG data in patients with darker skin (Fitzpatrick 5 or 6).
“Hochstadt et al. noted a linear regression coefficient of 0.98 (p < 0.001) when comparing PPG to ECG data in patients with darker skin (Fitzpatrick 5 or 6), suggesting that darker skin tone reduced accuracy, albeit with a relatively small impact [3].”
From Accuracy of heart rate measurement with wrist-worn wearable devices in various skin tones: a systematic review (2023) · cites this paper as [3]
Darker skin tone reduced accuracy in the Hochstadt et al. comparison, albeit with a relatively small impact.
“Hochstadt et al. noted a linear regression coefficient of 0.98 (p < 0.001) when comparing PPG to ECG data in patients with darker skin (Fitzpatrick 5 or 6), suggesting that darker skin tone reduced accuracy, albeit with a relatively small impact [3].”
From Accuracy of heart rate measurement with wrist-worn wearable devices in various skin tones: a systematic review (2023) · cites this paper as [3]
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- Authors
- Hochstadt, A., Havakuk, O., Chorin, E., Schwartz, A. L., Merdler, I., Laufer, M., Lubman, N., Ghantous, E., Viskin, S., & Rosso, R.
- Affiliations
- Tel Aviv University (IL)
- Corresponding author
- Hochstadt, Aviram
- ORCID
- Venue
- Journal of Electrocardiology
- Publisher
- Elsevier BV
- Published
- 2020-05
- Volume
- 60
- Pages
- 138-141
- ISSN
- 0022-0736 (ISSN-L)
- OpenAlex
- W3020495863
- Cited by
- 18
- References
- 18
- Citations by year
- 2026: 1 · 2025: 7 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 4
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Electrocardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Food and Drug Administration
- U.S. Food and Drug Administration
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- photoplethysmography, heart rate monitoring, atrial fibrillation detection, wearable sensors, outpatients, motion artifacts, arrhythmia detection
- MeSH terms
- Wearable Electronic Devices, Atrial Fibrillation, Electrocardiography, Heart Rate, Humans, Reproducibility of Results, Photoplethysmography, Monitoring, Ambulatory
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