Management of elderly patients suffering from cancer: Assessment of perceived burden and of quality of life of primary caregivers
Abstract
Objective To evaluate the perceived burden and the quality of life (QoL) at 3 and 6months of the primary caregiver (PC) of patients aged 70 and over suffering from cancer and the predictors of QoL in this population. Methods In this prospective observational study, 98 patients aged 70 and older with cancer and 96 PCs were included between 01/06/2014 and 18/03/2015. The Medical Outcomes Study 12-item Short Form Health Survey (SF-12) was used to assess the QoL of PCs and the Zarit Burden Interview (ZBI) was used to measure the perceived burden at 3 and 6months. The major determinants of QoL were identified using mixed linear models for the dimensions of the SF-12 that showed an average difference of at least 5 points between baseline and follow-up at 6months. Results The QoL scores of PCs showed a decrease in the dimensions "role emotional" and "bodily pain" over 6months. In multivariate analysis, the main determinants of QoL for "role emotional" were the PC's age (p=0.005), a low perceived burden (p Conclusion The main determinants of the QoL of PCs concerned factors inherent to the PC (age and perceived burden) and patient (functional independence).
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Using the 10 outcome events per predictor variable rule and considering a 70% prevalence of caregiver burden using the ZBI-22 cutoff score of 21, at least 214 participants were needed for logistic regression analysis including 15 predictor variables.
“Using the 10 outcome events per predictor variable (EPV) rule and considering a 70% prevalence of CB using the ZBI-22 cutoff score of 21 [20–24], at least 214 participants were needed for logistic regression analysis including 15 predictor variables.”
From Caregiver burden among family caregivers of incurable cancer patients in two eastern Mediterranean countries (2021) · cites this paper as [21]
The prevalence of caregiver burden among family caregivers of cancer patients in general using the ZBI-22 cutoff point of 21 ranged widely from 37 to 82% in other studies.
“The prevalence of CB among FCs of cancer patients in general using the ZBI-22 cutoff point of 21 ranged widely from 37 to 82% in other studies [9, 20–25].”
From Caregiver burden among family caregivers of incurable cancer patients in two eastern Mediterranean countries (2021) · cites this paper as [21]
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- Authors
- Germain, V., Dabakuyo-Yonli, T. S., Marilier, S., Putot, A., Bengrine-Lefevre, L., Arveux, P., Manckoundia, P., & Quipourt, V.
- Affiliations
- CHU Dijon Bourgogne (FR)
- Centre Georges François Leclerc (FR)
- Inserm (FR)
- Corresponding author
- Manckoundia, Patrick
- Venue
- Journal of Geriatric Oncology
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 8
- Issue
- 3
- Pages
- 220-228
- ISSN
- 1879-4068 (ISSN-L)
- OpenAlex
- W2559801411
- Cited by
- 26
- References
- 7
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 2 · 2020: 5 · 2019: 3 · 2018: 4 · 2017: 2
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Geriatric Oncology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- National Cancer Institute
- Topics
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Keywords
- elderly cancer patients, primary caregivers, caregiver burden, caregiver quality of life, older adults, functional independence, hormone therapy, Zarit Burden Interview, SF-12, predictors of quality of life
- MeSH terms
- Activities of Daily Living, Age Factors, Aged, 80 and over, Female, Humans, Longitudinal Studies, Male, Middle Aged, Neoplasms, Prospective Studies, Quality of Life, Surveys and Questionnaires, Time Factors, Caregivers, Cost of Illness, Disease Progression
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