Effects of gender and depressive symptoms on quality of life among colorectal and lung cancer patients and their family caregivers: Dyadic quality of life
Open accessAbstract
OBJECTIVE: Cancer patients and their family caregivers often report elevated levels of depressive symptoms, along with poorer mental and physical health (quality of life: QOL). Although the mutuality in distress between patients and their caregivers is relatively well known, unknown are the degree to which caregivers' depressive symptoms independently predict their patient's QOL and vice versa, and whether the relations vary by cancer type or gender. METHODS: Colorectal or lung cancer patients and their caregivers (398 dyads) provided complete data for study variables (212 colorectal cancer patient dyads, 186 lung cancer patient dyads; 257 male patient dyads, 141 female patient dyads). Patients' depressive symptoms and QOL were measured approximately 4 and 12 months post-diagnosis; caregivers' depressive symptoms and QOL were measured approximately 5 months post-diagnosis. RESULTS: The actor-partner interdependence model confirmed that each person's depressive symptom level was uniquely associated with his/her own concurrent QOL. Female patients' depressive symptoms were also related to their caregivers' poorer physical and better mental health, particularly when the pair's depressive symptoms were at similarly elevated level. On the other hand, male patients' elevated depressive symptoms were related to their caregivers' poorer mental health. CONCLUSIONS: Findings suggest that QOL among patients and their family caregivers is interdependent. In light of this interdependency, psychosocial interventions for managing depressive symptoms should target both patients and their family caregivers, from which both may benefit by not only alleviating depressive symptoms but also improving QOL.
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The challenging situation of partners of cancer patients often leads to increased psychological distress, increased caregiver strain, deteriorated physical health, and diminished social and relationship functioning.
“This challenging situation often leads to increased psychological distress (e.g., [5]), increased caregiver strain, deteriorated physical health, and diminished social and relationship functioning (e.g., [4, 6, 7]).”
From Web-based self-help intervention for partners of cancer patients based on acceptance and commitment therapy and self-compassion training: a randomized controlled trial with automated versus personal feedback (2021) · cites this paper as [6]
The Results (Prediction of QOL from Depressive Symptoms: Overall Sample) link caregivers’ depressive symptoms with poorer mental and physical health. The paper does not establish that caregiving generally causes physical health to deteriorate, and the passages do not support the attributed increases in caregiver strain or declines in social and relationship functioning. (LLM, conf=0.85)
Experimental — accuracy not yet measuredDistress in caregivers contributes to distress in patients, in addition to negatively impacting the health of caregivers themselves, and likely other family members.
“Distress in caregivers contributes to distress in patients [24], in addition to negatively impacting the health of caregivers themselves [2–4, 20, 21, 25], and likely other family members (e.g. many of our participants had young children).”
From Being present: A single-arm feasibility study of audio-based mindfulness meditation for colorectal cancer patients and caregivers (2018) · cites this paper as [24]
The introduction describes patient and caregiver distress as related and defines dyadic mutuality as one person’s dysphoria tending to influence the other. The Results report correlated depressive symptoms, but do not establish that caregiver distress causes patient distress; the Discussion also reports no association between caregivers’ depressive symptoms and patients’ quality of life in the groups examined. Citation [24] is attached only to the first clause, so the claims about caregivers’ and other family members’ health are not assessed here. (LLM, conf=0.85)
Experimental — accuracy not yet measuredA study of colorectal cancer patient-caregiver pairs (N = 212) found that quality of life and depressive symptoms were interdependent in patients and family members.
“A study of colorectal cancer patient-caregiver pairs (N = 212) found that quality of life and depressive symptoms were interdependent in patients and family members [24].”
From Being present: A single-arm feasibility study of audio-based mindfulness meditation for colorectal cancer patients and caregivers (2018) · cites this paper as [24]
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ปจจยทมความสมพนธกบความวตกกงวลของญาตผดแลเกยวกบความตายของผปวยมะเรงระยะลกลาม
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Components of family support in women with breast cancer: a systematic review
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“Despite studies showing that family caregivers of cancer patients face multiple physical challenges [5–7, 15] , which not only affect their quality of life but According to Fitch, spiritual needs are related to finding meaning and purpose in life and are associated with religious beliefs.”
- Authors
- Kim, Y., van Ryn, M., Jensen, R. E., Griffin, J. M., Potosky, A., & Rowland, J.
- Affiliations
- University of Miami (US)
- University of Minnesota Medical School; Minneapolis MN USA
- Georgetown University (US)
- Minneapolis VA Medical Center (US)
- National Cancer Institute (US)
- Corresponding author
- Kim, Youngmee
- Venue
- Psycho-Oncology
- Publisher
- Wiley
- Published
- 2014-05-16
- Volume
- 24
- Issue
- 1
- Pages
- 95-105
- ISSN
- 1057-9249 (ISSN-L)
- PMC
- PMC4233199
- OpenAlex
- W1497578487
- Cited by
- 99
- References
- 41
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 6 · 2022: 5 · 2021: 10 · 2020: 9 · 2019: 11 · 2018: 13 · 2017: 12 · 2016: 15 · 2015: 8
- FWCI
- 5.62
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psycho-Oncology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (U01 CA93324, U01 CA93326, U01 CA93329, U01 CA93332, U01 CA93339, U01 CA93344, and U01 CA93348)
- U.S. Department of Veterans Affairs (CRS 02-164)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Health Professions › Pharmacy › Nursing care and research
- Social Sciences › Sociology and Political Science › Family Support in Illness
- Keywords
- depressive symptoms, quality of life, family caregivers, colorectal cancer, lung cancer, gender differences, actor-partner interdependence, dyadic analysis, caregiver-patient relationship, cancer survivorship, psychosocial interventions
- MeSH terms
- Aged, Aged, 80 and over, Depression, Female, Humans, Longitudinal Studies, Lung Neoplasms, Male, Middle Aged, Quality of Life, Sex Factors, Colorectal Neoplasms, Cohort Studies, Caregivers
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