The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.
Connective Tissue and Fibroblast Senescence in Skin Aging
Open accessAbstract
There is increasing evidence that skin aging is significantly enforced by the accumulation of senescent dermal fibroblasts. Various stressors damaging macromolecules inside and outside fibroblasts are responsible. In addition, NK cells fail to adequately remove senescent (SEN) fibroblasts from tissues. SEN fibroblasts by the release of the proinflammatory, tissue degrading senescent-associated secretory phenotype factors and vesicles with distinct cargo impact on their endogenous niche and spread senescence and skin aging. In this review, we will further discuss less noticed facets, including the plasticity of distinct dermal fibroblast phenotypes, the underestimated impact of the extracellular matrix itself, and the depletion of fibroblast subsets on skin homeostasis and aging.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In contrast, the dermal region is more susceptible to photodamage, which results in loss of skin resilience [34].”
From Boosting the Photoaged Skin: The Potential Role of Dietary Components (2021) · cites this paper as [34]
Citations
Cites
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
Dimri, G. P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E. E., Linskens, M., Rubelj, I., & Pereira-Smith, O. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.20.9363 · Cited by 7,477
Telomeres shorten during ageing of human fibroblasts
Harley, C. B., Futcher, A. B., & Greider, C. W. (1990) · Nature · doi:10.1038/345458a0 · Cited by 5,750
The senescence-associated secretory phenotype: the dark side of tumor suppression
Coppé, J.-P., Desprez, P.-Y., Krtolica, A., & Campisi, J. (2010) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-121808-102144 · Cited by 5,206
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C.-P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., & Wright, W. E. (1998) · Science · doi:10.1126/science.279.5349.349 · Cited by 4,975
Cellular senescence: when bad things happen to good cells
Campisi, J., & d'Adda di Fagagna, F. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2233 · Cited by 4,441
A framework for advancing our understanding of cancer-associated fibroblasts
Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., et al. (2020) · Nature Reviews Cancer · doi:10.1038/s41568-019-0238-1 · Cited by 3,863
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Baker, D. J., Wijshake, T., Tchkonia, T., LeBrasseur, N. K., Childs, B. G., van de Sluis, B., Kirkland, J. L., & van Deursen, J. M. (2011) · Nature · doi:10.1038/nature10600 · Cited by 3,670
Cellular Senescence: Defining a Path Forward
Gorgoulis, V., Adams, P. D., Alimonti, A., Bennett, D. C., Bischof, O., Bishop, C., Campisi, J., Collado, M., Evangelou, K., Ferbeyre, G., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.005 · Cited by 3,225
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
Baker, D. J., Childs, B. G., Durik, M., Wijers, M. E., Sieben, C. J., Zhong, J., A. Saltness, R., Jeganathan, K. B., Verzosa, G. C., Pezeshki, A., et al. (2016) · Nature · doi:10.1038/nature16932 · Cited by 2,876
Cellular senescence: from physiology to pathology
Muñoz-Espín, D., & Serrano, M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3823 · Cited by 2,818
Cited by
Sorted by citations
Items 101–200 of 245
Wang, L., Jayawardena, T. U., Kim, Y.-S., Wang, K., Fu, X., Ahn, G., Cha, S., Kim, J. G., Lee, J.-S., & Jeon, Y. (2023) · Polymers · doi:10.3390/polym15163382 · Cited by 15
Sarandy, M. M., Gonçalves, R. V., & Valacchi, G. (2024) · Biomedicines · doi:10.3390/biomedicines12020348 · Cited by 16
A skin organoid-based infection platform identifies an inhibitor specific for HFMD
Li, J., Ma, J., Cao, R., Zhang, Q., Li, M., Wang, W., Wang, Y., Li, W., Zhu, Y., & Leng, L. (2025) · Nature Communications · doi:10.1038/s41467-025-57610-2 · Cited by 15
Martinović, D., Tokić, D., Usljebrka, M., Lupi-Ferandin, S., Cigić, L., Rogošić, L. V., Ercegovic, S., Kontić, M., Kumrić, M., Rušić, D., et al. (2023) · Life · doi:10.3390/life13020256 · Cited by 15
da Cruz, I. B. M., Bonotto, N. C. D. A., Turra, B. O., Teixeira, C. F., Azzolin, V. F., Ribeiro, E. A. M., Piccoli, J. D. C. E., & Barbisan, F. (2023) · Toxicology in Vitro · doi:10.1016/j.tiv.2023.105637 · Cited by 15
Fotopoulou, A., Angelopoulou, M. T., Pratsinis, H., Mavrogonatou, E., & Kletsas, D. (2024) · Aging Cell · doi:10.1111/acel.14422 · Cited by 14
Effect of stem cell secretome in skin rejuvenation: a narrative review
Hani, R., Khayat, L., Rahman, A. A., & Alaaeddine, N. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08622-y · Cited by 12
Bagheri, A. M., Ranjbar, M., Karami‐Mohajeri, S., Moshafi, M. H., Noudeh, Y. D., Ohadi, M., & Dehghannoudeh, G. (2024) · Journal of Cluster Science · doi:10.1007/s10876-024-02651-8 · Cited by 13
Wlaschek, M., Maity, P., Koroma, A. K., Geiger, H., Singh, K., & Scharffetter‐Kochanek, K. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.03.024 · Cited by 17
Self-citationKim, D.-Y., Lee, T., Lee, Y.-J., Ahn, S., Chu, B., Jung, D., Kim, Y., Seo, I.-S., Kim, W.-G., Cho, Y. J., et al. (2025) · Inflammation and Regeneration · doi:10.1186/s41232-025-00370-9 · Cited by 12
Mechanisms and Interventions of Diabetic Wound Healing
Feng, J., Lai, S., & Tang, D. (2025) · Current Diabetes Reviews · doi:10.2174/0115733998356905250706203510 · Cited by 14
Nosrati, F., Grillari, J., Azarnia, M., Nabiuni, M., Moghadasali, R., Karimzadeh, L., & Lämmermann, I. (2023) · Biogerontology · doi:10.1007/s10522-022-10013-y · Cited by 12
The role of sirtuins in dermal fibroblast function
Gilbert, M. M., Mathes, S. C., Mahajan, A. S., Rohan, C. A., Travers, J. B., & Thyagarajan‐Sahu, A. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1021908 · Cited by 15
Jin, R., Xu, H., Zhou, M., Lin, F., Xu, W., & Xu, A. (2023) · Inflammation · doi:10.1007/s10753-023-01922-2 · Cited by 11
Implanting mechanically reprogrammed fibroblasts for aged tissue regeneration and wound healing
Roy, B., Pekeč, T., Yuan, L., & Shivashankar, G. V. (2023) · Aging Cell · doi:10.1111/acel.14032 · Cited by 11
CASIN exerts anti‐aging effects through RPL4 on the skin of naturally aging mice
Zhang, Y., Wang, X., Huang, J., Zhang, X., Bu, L., Zhang, Y., Liang, F., Wu, S., Zhang, M., Zhang, L., et al. (2024) · Aging Cell · doi:10.1111/acel.14333 · Cited by 12
Yetukuri, K., & Umashankar, M. S. (2025) · Gels · doi:10.3390/gels11060400 · Cited by 11
Xu, Y., Zhang, Y., Wang, H., Tang, H., Zeng, W., & Wen, X. (2025) · Lasers in Surgery and Medicine · doi:10.1002/lsm.70033 · Cited by 11
Effect of Selected Antioxidants on the In Vitro Aging of Human Fibroblasts
Bartosz, G., Pieńkowska, N., & Sadowska‐Bartosz, I. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031529 · Cited by 11
Wu, S., Ouyang, Y., Hu, Y., Jiang, L., Fu, C., Lei, L., Zhang, Y., Guo, H., Huang, J., Chen, J., et al. (2024) · Clinical Immunology · doi:10.1016/j.clim.2024.110199 · Cited by 11
Systematic transcriptomic analysis and temporal modelling of human fibroblast senescence
Scanlan, R.-L., Pease, L., O’Keefe, H., Guimera, A. M., Rasmussen, L. J., Wordsworth, J., & Shanley, D. P. (2024) · Frontiers in Aging · doi:10.3389/fragi.2024.1448543 · Cited by 11
SenSkin™: a human skin-specific cellular senescence gene set
Wyles, S. P., Yu, G., Gânier, C., Tchkonia, T., Lynch, M. D., Kuchel, G. A., & Kirkland, J. L. (2025) · GeroScience · doi:10.1007/s11357-025-01568-y · Cited by 11
Tang, H., Xiong, Q., Yin, M., Feng, H., Yao, F., Xiao, X., Hu, F., & Liao, Y. (2023) · APOPTOSIS · doi:10.1007/s10495-023-01834-4 · Cited by 11
Lee, Y. I., Lee, S. G., Jung, I., Suk, J., Baeg, C., Han, S., Seo, J. Y., Jung, D., Jeon, Y., & Lee, J. H. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12072472 · Cited by 9
Interleukin-24: A molecular mediator of particulate matter’s impact on skin aging
Seong, S. H., Kim, J. Y., Kim, S. H., Lee, J., Lee, J., Bae, Y. J., Park, S., Kwon, I. J., Yoon, S.-M., Lee, J., et al. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116738 · Cited by 9
Zheng, H., Wu, J., Feng, J., & Cheng, H. (2024) · Clinical Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s403417 · Cited by 9
Melanocortin therapies to resolve fibroblast-mediated diseases
Khodeneva, N., Sugimoto, M. A., Davan-Wetton, C. S. A., & Montero‐Melendez, T. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1084394 · Cited by 10
Activity‐Dependent Induction of Younger Biological Phenotypes
Lissek, T. (2022) · Advanced Biology · doi:10.1002/adbi.202200119 · Cited by 9
Mormone, E., Cisternino, A., Capone, L., Caradonna, E., & Sbarbati, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042326 · Cited by 8
Hartinger, R., Singh, K., Leverett, J. C., & Djabali, K. (2024) · Biomolecules · doi:10.3390/biom14101310 · Cited by 8
Progress in skin gene therapy: From the inside and out
Osborn, M. J., Panda, S., Reineke, T. M., Tolar, J., & Nyström, A. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.03.017 · Cited by 9
Human dermal fibroblast senescence in response to single and recurring oxidative stress
McCarty, T. Y., & Kearney, C. J. (2025) · Frontiers in Aging · doi:10.3389/fragi.2025.1504977 · Cited by 8
Graphene oxide and condensed tannins enhance the efficacy of alginate hydrogels in wound management
González, L., Zapata, B., Figueroa, T., Ruíz, I., Montoya, L. F., Pino, E. J., Aguayo, C. R., Toledo, J. R., Romero, A., & Fernández, K. F. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.144082 · Cited by 8
Subcutaneous fat infiltration into the dermal layer induces wrinkle formation
Ezure, T. (2023) · Skin Research and Technology · doi:10.1111/srt.13296 · Cited by 8
Regulation of ENPP5, a senescence-associated secretory phenotype factor, prevents skin aging
Takaya, K., & Kishi, K. (2024) · Biogerontology · doi:10.1007/s10522-024-10096-9 · Cited by 10
The skin of the naked mole-rat and its resilience against aging and cancer
Wlaschek, M., Singh, K., Maity, P., & Scharffetter‐Kochanek, K. (2023) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2023.111887 · Cited by 7
Self-citationHe, Y.-L., Liu, Y., Lin, L., Mo, Y., Li, H., Zhou, C., Hong, P., & Qian, Z. (2024) · Algal Research · doi:10.1016/j.algal.2024.103615 · Cited by 7
Li, H., Zehang, S., Hong, J., Wen, Z., Shengli, Z., Bailing, C., Zhuning, C., & Kong, H. (2023) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2023.111808 · Cited by 7
Augello, F. R., Lombardi, F., Artone, S., Ciafarone, A., Altamura, S., Marzio, L. D., Cifone, M. G., Palumbo, P., Giuliani, M., & Cinque, B. (2023) · Biomedicines · doi:10.3390/biomedicines11092410 · Cited by 7
van Lessen, M., Mardaryev, A. N., Broadley, D., Bertolini, M., Edelkamp, J., Kückelhaus, M., Funk, W., Bı́ró, T., & Paus, R. (2023) · Experimental Dermatology · doi:10.1111/exd.14955 · Cited by 8
Omotezako, T., Zhao, W., Rodrigues, M., Ehrman, M. C., Deng, D., Lau, H., & Hakozaki, T. (2024) · Experimental Dermatology · doi:10.1111/exd.15163 · Cited by 6
Dong, C., Teng, C., Wang, L., Wang, Q., Wang, X., Xia, Y., Kuang, H., & Sun, Y. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.147601 · Cited by 6
Downregulated SPESP1‐driven fibroblast senescence decreases wound healing in aged mice
Zhong, Y., Zhou, L., Guo, Y., Wang, F., He, F., Cheng, Y., Meng, X., Xie, H., Zhang, Y., & Li, J. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.1660 · Cited by 5
Khalifian, S., McCarthy, A. D., & Yoelin, S. G. (2024) · Cureus · doi:10.7759/cureus.63969 · Cited by 6
Lee, S. W., Hyun, J., Shin, Y., & Goo, B. (2024) · Journal of Dermatological Treatment · doi:10.1080/09546634.2024.2333028 · Cited by 7
Zhu, L., Huang, W., Shi, J., Li, F., Sun, X., & Xiao, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.145467 · Cited by 6
Augello, F. R., Lombardi, F., Ciafarone, A., Altamura, S., Marazzato, M., Artone, S., Cinque, B., & Palumbo, P. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.117975 · Cited by 5
Zheng, W., Zhu, Z., Shi, Y., Wen, S., Ye, L., Man, M., Yang, B., & Liu, Z. (2022) · Lasers in Surgery and Medicine · doi:10.1002/lsm.23526 · Cited by 5
Nikolaev, V. V., Kistenev, Y. V., Kröger, M., Zuhayri, H., & Darvin, M. E. (2023) · Journal of Biophotonics · doi:10.1002/jbio.202300223 · Cited by 5
Athanasopoulou, S., Spanidi, E., Panagiotidou, E., Cavagnino, A., Bobier, A., & Gardikis, Κ. (2024) · Pharmaceuticals · doi:10.3390/ph17121610 · Cited by 5
Wang, F., Yi, C., Zhong, Y., Zhou, L., Meng, X., Mao, R., Guo, Y., Xie, H., Zhang, Y., Huang, Y., et al. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.11.028 · Cited by 5
Rad, A. N., Shams, G., Avelar, R. A., Morowvat, M. H., & Ghasemi, Y. (2022) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2022.100920 · Cited by 4
Promitotic Action of Oenothera biennis on Senescent Human Dermal Fibroblasts
Ceccacci, S., Roger, K., Metatla, I., Chhuon, C., Tighanimine, K., Fumagalli, S., Lucia, A. D., Pranke, I. M., Cordier, C., Monti, M. C., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232315153 · Cited by 6
Hautalterung – zelluläre Seneszenz
Scharffetter‐Kochanek, K., Wang, Y., Makrantonaki, E., Crișan, D., Wlaschek, M., Geiger, H., & Maity, P. (2023) · Die Dermatologie · doi:10.1007/s00105-023-05201-x · Cited by 5
Self-citationYang, F., Xiong, Y., Chen, S., Bie, F., Li, Z., Liu, H., Liu, L., Zhang, Z., & Chen, L. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102410 · Cited by 4
Potential dietary geroprotectors and their impact on key mechanisms of aging
Moskalev, A., & Veselova, O. M. (2025) · Biogerontology · doi:10.1007/s10522-025-10355-3 · Cited by 4
Koroma, A. K., Singh, K., Wang, Y., Krug, L., Haas, P., Wlaschek, M., Sakk, V., Schuster, T., Furst, D. E., Schrezenmeier, H., et al. (2026) · Aging Cell · doi:10.1111/acel.70398 · Cited by 5
Self-citationTopical and systemic skin aging interventions: Evidence, pitfalls and perspectives
Gürtler, A.-L., Sirois, J. P., Heckenbach, I., Scherf‐Clavel, O., Scheibye‐Knudsen, M., & Heinz, A. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.117898 · Cited by 6
Malfa, G. A., Bianchi, S., Spadaro, V., Kozuharova, E. K., Marino, P., Pappalardo, F., Giacomo, C. D., & Acquaviva, R. (2024) · Plants · doi:10.3390/plants13192748 · Cited by 4
Mechanisms of natural killer cell-mediated clearance of senescent renal tubular epithelial cells
Funk, N. D., Sinning, J., Schaser, P., Sörensen-Zender, I., Wulfmeyer, V. C., Schmidt-Ott, K. M., Brand, K., Halle, S., & Schmitt, R. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1597230 · Cited by 4
Wang, F., Zhou, L., Zhong, Y., Cai, Y., Meng, X., Chen, M., Mao, R., Xiao, X., Yi, C., Guo, Y., et al. (2025) · MedComm · doi:10.1002/mco2.70205 · Cited by 4
Liu, H., Zheng, H., Zhou, S., & Lin, Q. (2024) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.16515 · Cited by 3
Augello, F. R., Lombardi, F., Ciafarone, A., Ciummo, V., Altamura, S., Giuliani, M., Cinque, B., & Palumbo, P. (2024) · Biomedicines · doi:10.3390/biomedicines12092030 · Cited by 4
Systemic comparison of molecular characteristics in different skin fibroblast senescent models
Fang, X., Zhang, S., Wu, M., Luo, Y., Chen, X., Zhou, Y., Zhang, Y., Liu, X., & Yao, X. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003312 · Cited by 5
Heisler, E. V., Turra, B. O., Bonotto, N. C. D. A., da Cruz, I. B. M., Montano, M. A. E., Azzolin, V. F., Magro, J. D., Zaniol, F., Perottoni, J., Chelotti, M. E., et al. (2024) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2024/2812290 · Cited by 4
Pathogenesis and prevention of skin aging
Cho, S. (2021) · Journal of Korean Medical Association · doi:10.5124/jkma.2021.64.6.438 · Cited by 4
Ministrini, S., Liberale, L., Erle, H.-E., Percoco, G., Tfayli, A. M., Assi, A., Kapitonov, I., Greiner, I., & Camici, G. G. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47090722 · Cited by 4
Exploring glycobiomarkers beyond senescence-associated β-galactosidase for studying aging in vitro
Račková, L., Kodríková, R., Nemčovič, M., Csekes, E., & Pakanová, Z. (2025) · Biochimie · doi:10.1016/j.biochi.2025.09.005 · Cited by 3
Semyichkina-Glushkovskaia, A., Blokhina, I., Fedosov, I. V., Shirokov, A. A., Tsoy, M. O., Dubrovsky, A. I., Dmitrenko, A. V., Terskov, A. V., Zlatogorskaya, D., Adushkina, V., et al. (2025) · Biomedical Optics Express · doi:10.1364/boe.577347 · Cited by 3
Yao, W.-H., Sun, C., Su, Z., Wang, P., & Zeng, Y. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s558464 · Cited by 3
Huang, Z., Zhang, R., Sheng, M., Tian, T., Xu, B., Wang, F., & Liu, D. (2025) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70529 · Cited by 3
Monopolar Radiofrequency for Dermal Prejuvenation: Scientific Rationale and Mechanisms of Action
Kilmer, S. L., Avram, M. M., Bhatia, A. C., Lee, N. Y., & Jacobson, A. A. (2025) · Lasers in Surgery and Medicine · doi:10.1002/lsm.70087 · Cited by 4
The orchestrated network of skin photoaging: From intercellular crosstalk to molecular signaling
Li, B., Ren, C., Zhang, L., & Gu, W. (2026) · BioScience Trends · doi:10.5582/bst.2026.01042 · Cited by 4
Machaliński, B., Oszutowska–Mazurek, D., Mazurek, P., Parafiniuk, M., Szumilas, P., Zawiślak, A., Zaremba, M., Stecewicz, I., Zawodny, P., & Wiszniewska, B. (2024) · Biology · doi:10.3390/biology13080636 · Cited by 5
Herbal Extracts in Anti-Aging Products
Asuku, A. O., Ajibare, A. J., Ajagun, E. J., Saliu, S. B., Olajide, T. S., Oyerinde, T. O., Ogungbangbe, G. O., & Odugbesan, O. A. (2024) · Advances in chemical and materials engineering book series · doi:10.4018/979-8-3693-5473-5.ch012 · Cited by 3
Kim, M., Kim, D., Jang, H. Y., & Park, J. H. (2025) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-025-00195-w · Cited by 3
Nanotechnology-Based Approaches for Combating Skin Aging: A Comprehensive Review
Mitali, Singh, M., & Mishra, A. K. (2025) · Current Aging Science · doi:10.2174/0118746098384581250904035955 · Cited by 4
Wyles, S. P., Vyas, K. S., Wasserburg, J. R., Ansaf, R. B., & Kirkland, J. L. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15500-0.00009-8 · Cited by 3
BRD4 plays an antiaging role in the senescence of renal tubular epithelial cells
Bo, Y., Zhang, Y., Lu, W., Pei, X., Zhu, B., Zanoli, L., Kalantar‐Zadeh, K., Gao, F., Yong, Z., Zhang, T., et al. (2024) · Translational Andrology and Urology · doi:10.21037/tau-24-214 · Cited by 2
Jiang, H., Li, J., Luo, S., Cui, C., Luo, L., Li, Y., & Liang, Z. (2025) · Carbohydrate Research · doi:10.1016/j.carres.2025.109648 · Cited by 2
Gu, X., Wang, J., Chen, J., Lv, Z., Wu, S., Li, B., Liu, G., Wang, X., Qian, T., & Wu, Y. (2026) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2026.2635734 · Cited by 2
Azim, M. M. N., Lee, Y. K., Alam, M. J., Kim, J., & Park, J. H. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119441 · Cited by 4
Skin aging: Mechanistic insights and targeted therapeutic strategies
Beaziz, J., Avallone, G., Langer, K., DUCA, E. D., Navrazhina, K., He, H., & Guttman‐Yassky, E. (2026) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2026.05.015 · Cited by 3
Zorina, A. I., Zorin, V. L., Kopnin, P., Ustyugov, A. Y., & Manturova, N. E. (2023) · Russian Journal of Clinical Dermatology and Venereology · doi:10.17116/klinderma202322031338 · Cited by 2
Takaya, K., Asou, T., & Kishi, K. (2023) · Rejuvenation Research · doi:10.1089/rej.2023.0020 · Cited by 2
Potential anti-aging applications of microbial-derived surfactantsin cosmetic formulations
Bagheri, A. M., Mirzahashemi, M., Salarpour, S., Dehghnnoudeh, Y., Banat, I. M., Ohadi, M., & Dehghannoudeh, G. (2024) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2024.2393420 · Cited by 3
Ma, X., Wei, W., Zeng, H., & Dong, M. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.103049 · Cited by 2
Rink, L., & Weßels, I. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818731-9.00072-0 · Cited by 2
Cell Senescence-Independent Ageing of Human SkinPreprint
Wordsworth, J., Fullard, N., Welsh, C. E., Maltman, D. J., Bascom, C. C., Tasseff, R. A., Isfort, R. J., Costello, L., Scanlan, R., Przyborski, S. A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.15.504045 · Cited by 2
Genetic and Epigenetic Influences on Cutaneous Cellular Senescence
Sarkar, T. J., Hermsmeier, M., Ross, J. L., & Herron, G. S. (2021) · Physiology · doi:10.5772/intechopen.101152 · Cited by 1
Takaya, K., & Kishi, K. (2024) · Biogerontology · doi:10.1007/s10522-024-10135-5 · Cited by 1
Xu, X., Lu, X., Chen, X., Yao, A., & Wei, L. (2025) · Journal of Cosmetic Dermatology · doi:10.1111/jocd.70098 · Cited by 1
Georgieva, M., Vasileva, B., Ivanov, P., Hristova‐Panusheva, K., Paunova-Krasteva, T. S., Lesov, I., Gospodinova, Z., Krasteva, N. A., Miloshev, G. A., & Georgiev, V. (2025) · Cosmetics · doi:10.3390/cosmetics12030090 · Cited by 1
Pratsinis, H., Gianniou, D. D., Ringele, G. B. L., Agalou, A., Fotopoulou, A., Louka, X. P., Nastos, C., Kalpoutzakis, E., Argyropoulou, A., Michailidis, D., et al. (2025) · Antioxidants · doi:10.3390/antiox14070824 · Cited by 1
Wu, T., Xia, J., Shao, Y., Yang, J., Zou, C., Wang, J., & Sun, G. (2025) · Journal of Future Foods · doi:10.1016/j.jfutfo.2025.05.006 · Cited by 1
Multifaceted Roles of Dermal Fibroblasts in Skin Health and Disease
Galati, A., Gallo, R. L., & Cavagnero, K. J. (2025) · Dermatologic Surgery · doi:10.1097/dss.0000000000004668 · Cited by 1
From Lasers to Longevity: Exploring Energy-Based Devices as Senotherapeutic Tools in Dermatology
Hrițcu, O. M. C., Costan, V. V., Toader, Ș. V., Branisteanu, D. E., & Toader, M. P. (2025) · Cosmetics · doi:10.3390/cosmetics12050201 · Cited by 1
HOXC10 Protects from Skin Aging by Targeting the FZD6/Wnt/β-Catenin Signaling Pathway
Zhong, Y., Guo, Y., Mao, R., Zhou, L., Wang, F., Meng, X., Xiao, X., Yuan, H., Zhang, Y., Deng, Z., et al. (2025) · Research · doi:10.34133/research.0976 · Cited by 2
Åkerström, U., Gaudicheau, C., Locret, B., & Gillbro, J. M. (2025) · Cosmetics · doi:10.3390/cosmetics12060235 · Cited by 1
Chen, T., Chen, X., Chen, X., Zhang, W., Li, B., Chu, C., Lv, G., & Chen, S. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.121233 · Cited by 2
Metadata
- Authors
- Wlaschek, M., Maity, P., Makrantonaki, E., & Scharffetter-Kochanek, K.
- Affiliations
- Universität Ulm (DE)
- Venue
- Journal of Investigative Dermatology
- Publisher
- Elsevier BV
- Published
- 2021-04
- Volume
- 141
- Issue
- 4
- Pages
- 985-992
- ISSN
- 0022-202X (ISSN-L)
- OpenAlex
- W3126843737
- Semantic Scholar
- 4870ccd091834d4e0584823f87394b1665d80d2c
- Cited by
- 245
- References
- 128
- Citations by year
- 2026: 29 · 2025: 55 · 2024: 57 · 2023: 49 · 2022: 36 · 2021: 19
- FWCI
- 5.37
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Investigative Dermatology (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Keywords
- skin aging, dermal fibroblasts, fibroblast senescence, senescence-associated secretory phenotype, extracellular vesicles, extracellular matrix, natural killer cells, senescence-associated inflammation, skin homeostasis, connective tissue
- MeSH terms
- Animals, Cell Communication, Connective Tissue, Extracellular Matrix, Fibroblasts, Humans, Killer Cells, Natural, Skin, Skin Aging, Cellular Senescence, Models, Animal, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
