Unraveling the molecular details involved in the intimate link between the immune and neuroendocrine systems

Innate immune recognition

Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.083001.084359 · Cited by 8,394 · see citing works

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631 · see citing works

Toll-Like Receptors

Takeda, K., Kaisho, T., & Akira, S. (2003) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141126 · Cited by 6,143 · see citing works

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., & Bauer, S. (2004) · Science · doi:10.1126/science.1093620 · Cited by 3,947 · see citing works

Missing Pieces in the NF-κB Puzzle

Ghosh, S., & Karin, M. (2002) · Cell · doi:10.1016/s0092-8674(02)00703-1 · Cited by 3,638 · see citing works

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., & Reis e Sousa, C. (2004) · Science · doi:10.1126/science.1093616 · Cited by 3,444 · see citing works

Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the <i>Lps</i> Gene Product

Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., & Akira, S. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.7.3749 · Cited by 3,374 · see citing works

Prostanoid Receptors: Structures, Properties, and Functions

Narumiya, S., Sugimoto, Y., & Ushikubi, F. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.4.1193 · Cited by 2,414 · see citing works

Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action

TURNBULL, A. V., & RIVIER, C. L. (1999) · Physiological Reviews · doi:10.1152/physrev.1999.79.1.1 · Cited by 1,297 · see citing works

A Toll-like Receptor That Prevents Infection by Uropathogenic Bacteria

Zhang, D., Zhang, G., Hayden, M. S., Greenblatt, M. B., Bussey, C., Flavell, R. A., & Ghosh, S. (2004) · Science · doi:10.1126/science.1094351 · Cited by 1,002 · see citing works

The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression

De Bosscher, K., Vanden Berghe, W., & Haegeman, G. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0006 · Cited by 898 · see citing works

Inflammatory Resolution: new opportunities for drug discovery

Gilroy, D. W., Lawrence, T., Perretti, M., & Rossi, A. G. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1383 · Cited by 772 · see citing works

The Toll-receptor family and control of innate immunity.

Kopp, E., & Medzhitov, R. (1999) · Current Opinion in Immunology · doi:10.1016/s0952-7915(99)80003-x · Cited by 734 · see citing works

Molecular Identification of Cytosolic Prostaglandin E2 Synthase That Is Functionally Coupled with Cyclooxygenase-1 in Immediate Prostaglandin E2Biosynthesis

Tanioka, T., Nakatani, Y., Semmyo, N., Murakami, M., & Kudo, I. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003504200 · Cited by 708 · see citing works

Innate immunity: the missing link in neuroprotection and neurodegeneration?

Nguyen, M. D., Julien, J., & Rivest, S. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn752 · Cited by 698 · see citing works

A functional anatomical analysis of central pathways subserving the effects of interleukin-1 on stress-related neuroendocrine neurons

Ericsson, A. B., Kovacs, K., & Sawchenko, P. E. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-02-00897.1994 · Cited by 684 · see citing works

Toll-like receptors: key mediators of microbe detection

Underhill, D. M., & Ozinsky, A. (2002) · Current Opinion in Immunology · doi:10.1016/s0952-7915(01)00304-1 · Cited by 684 · see citing works

Endogenous ligands of Toll-like receptors

Tsan, M., & Gao, B. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0304127 · Cited by 683 · see citing works

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

Ushikubi, F., Segi, E., Sugimoto, Y., Murata, T., Matsuoka, T., Kobayashi, T., Hizaki, H., Tuboi, K., Katsuyama, M., Ichikawa, A., et al. (1998) · Nature · doi:10.1038/26233 · Cited by 677 · see citing works

Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

Warner, T. D., & Mitchell, J. A. (2004) · The FASEB Journal · doi:10.1096/fj.03-0645rev · Cited by 613 · see citing works

How we detect microbes and respond to them: the Toll-like receptors and their transducers

Beutler, B., Hoebe, K. H. N., Du, X., & Ulevitch, R. J. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0203082 · Cited by 592 · see citing works

Recognition of microbial infection by Toll-like receptors

Kopp, E. B., & Medzhitov, R. M. (2003) · Current Opinion in Immunology · doi:10.1016/s0952-7915(03)00080-3 · Cited by 547 · see citing works

Toll‐like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram‐negative bacterial cell wall components

LAFLAMME, N., & RIVEST, S. (2001) · The FASEB Journal · doi:10.1096/fj.00-0339com · Cited by 501 · see citing works

Molecular insights on the cerebral innate immune system

Rivest, S. (2003) · Brain Behavior and Immunity · doi:10.1016/s0889-1591(02)00055-7 · Cited by 417 · see citing works

Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice

Chai, Z., Gatti, S., Toniatti, C., Poli, V., & Bartfai, T. (1996) · Journal of Experimental Medicine · doi:10.1084/jem.183.1.311 · Cited by 376 · see citing works

How the immune system works to protect the host from infection: A personal view

Janeway, C. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.131202998 · Cited by 356 · see citing works

Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia

Simard, A. R., & Rivest, S. (2004) · The FASEB Journal · doi:10.1096/fj.04-1517fje · Cited by 354 · see citing works

Different Toll-like receptor agonists induce distinct macrophage responses

Jones, B. W., Means, T. K., Heldwein, K. A., Keen, M. A., Hill, P. J., Belisle, J. T., & Fenton, M. J. (2001) · Journal of Leukocyte Biology · doi:10.1189/jlb.69.6.1036 · Cited by 353 · see citing works

Pathway across the blood–brain barrier

Ek, M., Engblom, D., Saha, S., Blomqvist, A. G., Jakobsson, P., & Ericsson‐Dahlstrand, A. (2001) · Nature · doi:10.1038/35068632 · Cited by 347 · see citing works

Cellular Prostaglandin E2 Production by Membrane-bound Prostaglandin E Synthase-2 via Both Cyclooxygenases-1 and -2

Murakami, M., Nakashima, K., Kamei, D., Masuda, S., Ishikawa, Y., Ishii, T., Ohmiya, Y., Watanabe, K., & Kudo, I. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305108200 · Cited by 344 · see citing works

Mechanisms of CNS response to systemic immune challenge: the febrile response

Elmquist, J. K., Scammell, H. E., & Saper, C. B. (1997) · Trends in Neurosciences · doi:10.1016/s0166-2236(97)01138-7 · Cited by 333 · see citing works

Regulation of the Genes Encoding Interleukin‐6, Its Receptor, and gp130 in the Rat Brain in Response to the Immune Activator Lipopolysaccharide and the Proinflammatory Cytokine Interleukin‐1β

Vallières, L., & Rivest, S. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69041668.x · Cited by 323 · see citing works

Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis

Engblom, D., Saha, S., Engström, L., Westman, M., Audoly, L., Jakobsson, P., & Blomqvist, A. G. (2003) · Nature Neuroscience · doi:10.1038/nn1137 · Cited by 310 · see citing works

Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1β: a possible site of prostaglandin synthesis responsible for fever

Cao, C., Matsumura, K., Yamagata, K., & Watanabe, Y. (1996) · Brain Research · doi:10.1016/0006-8993(96)00575-6 · Cited by 308 · see citing works

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages

Elmquist, J. K., Breder, C. D., Sherin, J. E., Scammell, T. E., Hickey, W. F., DeWitt, D. L., & Saper, C. B. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970505)381:2 · Cited by 282 · see citing works

Evidence for an Intramedullary Prostaglandin-Dependent Mechanism in the Activation of Stress-Related Neuroendocrine Circuitry by Intravenous Interleukin-1

Ericsson, A. B., Arias, C., & Sawchenko, P. E. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07166.1997 · Cited by 281 · see citing works

Reduced Pain Hypersensitivity and Inflammation in Mice Lacking Microsomal Prostaglandin E Synthase-1

Kamei, D., Yamakawa, K., Takegoshi, Y., Mikami-Nakanishi, M., Nakatani, Y., Oh‐ishi, S., Yasui, H., Azuma, Y., Hirasawa, N., Ohuchi, K., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400199200 · Cited by 278 · see citing works

Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions. Review.

Lossinsky, A. S., & Shivers, R. R. (2004) · PubMed · doi:10.14670/hh-19.535 · Cited by 275 · see citing works

Local circuit regulation of paraventricular nucleus stress integration

Herman, J. P., Tasker, J. G., Ziegler, D. R., & Cullinan, W. E. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00681-5 · Cited by 274 · see citing works

Region-Specific Regulation of Glutamic Acid Decarboxylase (GAD) mRNA Expression in Central Stress Circuits

Bowers, G., Cullinan, W. E., & Herman, J. P. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-15-05938.1998 · Cited by 250 · see citing works

Brain Endothelial Cells Express Cyclooxygenase-2 during Lipopolysaccharide-Induced Fever: Light and Electron Microscopic Immunocytochemical Studies

Matsumura, K., Cao, C., Ozaki, M., Morii, H., Nakadate, K., & Watanabe, Y. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-16-06279.1998 · Cited by 247 · see citing works

Distribution of vesicular glutamate transporter mRNA in rat hypothalamus

Ziegler, D. R., Cullinan, W. E., & Herman, J. P. (2002) · Journal of Comparative Neurology · doi:10.1002/cne.10257 · Cited by 241 · see citing works

Prostaglandin E2 as a mediator of fever: synthesis and catabolism

Andrei, I. I. (2004) · Frontiers in bioscience · doi:10.2741/1383 · Cited by 239 · see citing works

Prostaglandin E synthase

Murakami, M., Nakatani, Y., Tanioka, T., & Kudo, I. (2002) · Prostaglandins & Other Lipid Mediators · doi:10.1016/s0090-6980(02)00043-6 · Cited by 231 · see citing works

The Bacterial Endotoxin Lipopolysaccharide has the Ability to Target the Brain in Upregulating Its Membrane CD14 Receptor Within Specific Cellular Populations

Lacroix, S., Feinstein, D., & Rivest, S. (1998) · Brain Pathology · doi:10.1111/j.1750-3639.1998.tb00189.x · Cited by 223 · see citing works

Prostaglandin E Synthase

National Cancer Institute (2020) · Definitions · doi:10.32388/aqq6w5 · Cited by 220 · see citing works

Role of Microglial-Derived Tumor Necrosis Factor in Mediating CD14 Transcription and Nuclear Factor κ B Activity in the Brain during Endotoxemia

Nadeau, S., & Rivest, S. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-09-03456.2000 · Cited by 217 · see citing works

Distribution, regulation and colocalization of the genes encoding the EP2‐ and EP4‐PGE2 receptors in the rat brain and neuronal responses to systemic inflammation

Zhang, J., & Rivest, S. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00682.x · Cited by 216 · see citing works

Suppression of fever after lesions of the anteroventral third ventricle in guinea pigs

Blatteis, C. M., Bealer, S. L., Hunter, W. S., Llanos, J.-Q., Ahokas, R. A., & Mashburn, T. A. (1983) · Brain Research Bulletin · doi:10.1016/0361-9230(83)90124-7 · Cited by 213 · see citing works

Distinct Brain Vascular Cell Types Manifest Inducible Cyclooxygenase Expression as a Function of the Strength and Nature of Immune Insults

Schiltz, J. C., & Sawchenko, P. E. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-13-05606.2002 · Cited by 195 · see citing works

Glucocorticoids Play a Fundamental Role in Protecting the Brain during Innate Immune Response

Nadeau, S., & Rivest, S. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-13-05536.2003 · Cited by 190 · see citing works

Characteristics of thermoregulatory and febrile responses in mice deficient in prostaglandin EP1 and EP3 receptors

Oka, T., Oka, K., Kobayashi, T., Sugimoto, Y., Ichikawa, A., Ushikubi, F., Narumiya, S., & Saper, C. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.048140 · Cited by 189 · see citing works

Circulating cell wall components derived from gram‐negative, not gram‐positive, bacteria cause a profound induction of the gene‐encoding Toll‐like receptor 2 in the CNS

Laflamme, N., Soucy, G., & Rivest, S. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00603.x · Cited by 185 · see citing works

Microsomal Prostaglandin E Synthase-1 Is a Major Terminal Synthase That Is Selectively Up-Regulated During Cyclooxygenase-2-Dependent Prostaglandin E2 Production in the Rat Adjuvant-Induced Arthritis Model

Claveau, D., Sirinyan, M., Guay, J., Gordon, R. J., Chan, C., Bureau, Y., Riendeau, D., & Mancini, J. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.9.4738 · Cited by 182 · see citing works

A novel role for phospholipase A 2 isoforms in the checkpoint control of acute inflammation

Gilroy, D. W., Newson, J., Sawmynaden, P., Willoughby, D. A., & Croxtall, J. D. (2004) · The FASEB Journal · doi:10.1096/fj.03-0837com · Cited by 175 · see citing works

Origin of microglia

Kaur, C., Hao, A., Wu, C., & Ling, E. (2001) · Microscopy Research and Technique · doi:10.1002/jemt.1114 · Cited by 174 · see citing works

Cyclooxygenase 2 mRNA expression in rat brain after peripheral injection of lipopolysaccharide

Quan, N., Whiteside, M. B., & Herkenham, M. A. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00402-8 · Cited by 172 · see citing works

Role of the paraventricular nucleus microenvironment in stress integration

Herman, J. P., Cullinan, W. E., Ziegler, D. R., & Tasker, J. G. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02133.x · Cited by 168 · see citing works

Cooperation between toll‐like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram‐negative and gram‐positive bacteria

Laflamme, N., Echchannaoui, H., Landmann, R. M., & Rivest, S. (2003) · European Journal of Immunology · doi:10.1002/eji.200323821 · Cited by 160 · see citing works

Toll-like receptors: how they work and what they do

Beutler, B. (2002) · Current opinion in hematology · doi:10.1097/00062752-200201000-00002 · Cited by 153 · see citing works

Prostaglandin E2-synthesizing enzymes in fever: differential transcriptional regulation

Ivanov, A. I., Pero, R. S., Scheck, A. C., & Romanovsky, A. A. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00347.2002 · Cited by 152 · see citing works

Noradrenergic depletion increases inflammatory responses in brain: effects on IκB and HSP70 expression

Heneka, M. T., Gavrilyuk, V., Landreth, G. E., O’Banion, M. K., Weinberg, G. L., & Feinstein, D. L. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01694.x · Cited by 142 · see citing works

Signaling the brain in systemic inflammation the role of perivascular cells

Sawchenko, P. E. (2003) · Frontiers in bioscience · doi:10.2741/1211 · Cited by 129 · see citing works

Mapping of prostaglandin E2 binding sites in rat brain using quantitative autoradiography

Matsumura, K., Watanabe, Y., Imai-Matsumura, K., Connolly, M., Koyama, Y., Onoe, H., & Watanabe, Y. (1992) · Brain Research · doi:10.1016/0006-8993(92)90720-t · Cited by 128 · see citing works

High density of prostaglandin E2 binding sites in the anterior wall of the 3rd ventricle: a possible site of its hyperthermic action

Matsumura, K., Watanabe, Y., Onoe, H., Watanabe, Y., & Hayaishi, O. (1990) · Brain Research · doi:10.1016/0006-8993(90)91808-t · Cited by 117 · see citing works

Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes

Matsuoka, Y., Furuyashiki, T., Bito, H., Ushikubi, F., Tanaka, Y. R., Kobayashi, T., Muro, S., Satoh, N., Kayahara, T., Higashi, M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0633341100 · Cited by 110 · see citing works

Lipopolysaccharide Injected into the Cerebral Ventricle Evokes Fever through Induction of Cyclooxygenase-2 in Brain Endothelial Cells

Cao, C., Matsumura, K., Ozaki, M., & Watanabe, Y. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-02-00716.1999 · Cited by 105 · see citing works

Specific roles of cyclooxygenase‐1 and cyclooxygenase‐2 in lipopolysaccharide‐induced fever and fos expression in rat brain

Zhang, Y., Lu, J., Elmquist, J. K., & Saper, C. B. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10743 · Cited by 102 · see citing works

Cyclooxygenase-2 is induced in brain blood vessels during fever evoked by peripheral or central administration of tumor necrosis factor

Cao, C., Matsumura, K., Yamagata, K., & Watanabe, Y. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00025-4 · Cited by 101 · see citing works

Endotoxemia prevents the cerebral inflammatory wave induced by intraparenchymal lipopolysaccharide injection: role of glucocorticoids and CD14

Nadeau, S., & Rivest, S. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.6.3370 · Cited by 94 · see citing works

Polyamines play a critical role in the control of the innate immune response in the mouse central nervous system

Soulet, D., & Rivest, S. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200301097 · Cited by 93 · see citing works

IMMUNOLOGY: After the Toll Rush

O'Neill, L. A. J. (2004) · Science · doi:10.1126/science.1096113 · Cited by 86 · see citing works

Microglia: its development and role as a neuropathology sensor

Ling, E., Ng, Y. K., Wu, C., & Kaur, C. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)32066-6 · Cited by 83 · see citing works

Area postrema removal abolishes stimulatory effects of intravenous interleukin-1β on hypothalamic-pituitary-adrenal axis activity and c-fos mRNA in the hypothalamic paraventricular nucleus

Lee, H. Y., Whiteside, M. B., & Herkenham, M. A. (1998) · Brain Research Bulletin · doi:10.1016/s0361-9230(98)00045-8 · Cited by 78 · see citing works

Molecular Characterization of the Mouse Prostanoid EP1 Receptor Gene

Båtshake, B., Nilsson, C. F., & Sundelin, J. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.0809d.x · Cited by 76 · see citing works

c-Fos generation in the dorsal vagal complex after systemic endotoxin is not dependent on the vagus nerve

Hermann, G. E., Emch, G. S., Tovar, C. A., & Rogers, R. C. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.1.r289 · Cited by 76 · see citing works

What is the cellular source of prostaglandins in the brain in response to systemic inflammation? Facts and controversies

Rivest, S. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000676 · Cited by 76 · see citing works

A Functional Analysis of EP4 Receptor‐Expressing Neurons in Mediating the Action of Prostaglandin E2 Within Specific Nuclei of the Brain in Response to Circulating Interleukin‐1β

Zhang, J., & Rivest, S. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0742134.x · Cited by 73 · see citing works

Role of the anteroventral third ventricle region in fever in sheep

Blatteis, C. M., Hales, J. R. S., McKinley, M. J., & Fawcett, A. A. (1987) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y87-200 · Cited by 66 · see citing works

Prostanoids in immunity: Roles revealed by mice deficient in their receptors

Narumiya, S. (2003) · Life Sciences · doi:10.1016/j.lfs.2003.09.025 · Cited by 64 · see citing works

Inhibitory Action of Nitric Oxide on Circulating Tumor Necrosis Factor-Induced NF-κB Activity and COX-2 Transcription in the Endothelium of the Brain Capillaries

Blais, V., & Rivest, S. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.9.893 · Cited by 62 · see citing works

Quantitative autoradiographic localization of prostaglandin E2 binding sites in monkey diencephalon

Watanabe, Y., Watanabe, Y., & Hayaishi, O. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-06-02003.1988 · Cited by 61 · see citing works

EP1-receptor mediation of prostaglandin E2-induced hyperthermia in rats

Oka, T., & Hori, T. (1994) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1994.267.1.r289 · Cited by 60 · see citing works

Molecular Characterization of the Mouse Prostanoid EP1 Receptor Gene

Båtshake, B., Nilsson, C. F., & Sundelin, J. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.tb20765.x · Cited by 60 · see citing works

Contrasting effects of E type prostaglandin (EP) receptor agonists on core body temperature in rats

Oka, T., Oka, K., & Saper, C. B. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02268-6 · Cited by 56 · see citing works

Visualization and Mechanism of Assembly of a Glucocorticoid Receptor·Hsp70 Complex That Is Primed for Subsequent Hsp90-dependent Opening of the Steroid Binding Cleft

Murphy, P. J. M., Morishima, Y., Chen, H., Galigniana, M. D., Mansfield, J. F., Simons, S. S., & Pratt, W. B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304469200 · Cited by 53 · see citing works

Involvement of Arachidonic Acid Cascade Pathways in lnterleukin-6-Stimulated Corticotropin-Releasing Factor Release in vitro

Lyson, K., & McCann, S. M. (2008) · Neuroendocrinology · doi:10.1159/000126190 · Cited by 50 · see citing works

Norepinephrine–gamma-aminobutyric acid (GABA) interaction in limbic stress circuits: effects of reboxetine on GABAergic neurons

Herman, J. P., Renda, A. M., & Bodie, B. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01449-x · Cited by 50 · see citing works

The complement system is an integrated part of the natural innate immune response in the brain

Nadeau, S., & Rivest, S. (2001) · The FASEB Journal · doi:10.1096/fj.00-0709fje · Cited by 49 · see citing works

Blockade by interleukin-1 receptor antagonist of IL-1β-induced neuronal activity in guinea pig preoptic area slices

Li, X., & Blatteis, C. M. (1992) · Brain Research · doi:10.1016/0006-8993(92)90650-x · Cited by 45 · see citing works

Involvement of Postsynaptic EP4 and Presynaptic EP3 Receptors in Actions of Prostaglandin E2 in Rat Supraoptic Neurones

Shibuya, I., Setiadji, S., Ibrahim, N., Harayama, N., Maruyama, T., Ueta, Y., & Yamashita, H. (2002) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2002.00741.x · Cited by 36 · see citing works

Activation of prostanoid EP3 and EP4 receptor mRNA‐expressing neurons in the rat parabrachial nucleus by intravenous injection of bacterial wall lipopolysaccharide

Engblom, D., Ek, M., Ericsson‐Dahlstrand, A., & Blomqvist, A. G. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1391 · Cited by 36 · see citing works

Induction of Cyclooxygenase‐2 in the Brain by Cytokines

Cao, C., Matsumura, K., & Watanabe, Y. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb51710.x · Cited by 28 · see citing works

Differential regulation of forebrain glutamic acid decarboxylase mRNA expression by aging and stress

Herman, J. P., & Larson, B. R. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02641-5 · Cited by 28 · see citing works

Effects of centrally administered prostaglandin EP receptor agonists on febrile and adrenocortical responses in the prepubertal pig

Parrott, R. F., & Vellucci, S. V. (1996) · Brain Research Bulletin · doi:10.1016/0361-9230(96)00156-6 · Cited by 25 · see citing works

Rôle de la réponse immunitaire innée dans le cerveau

Blais, V., & Rivest, S. (2003) · médecine/sciences · doi:10.1051/medsci/20031910981 · Cited by 16 · see citing works

Electron Microscopic Evidence for Induction of Cyclooxygenase‐2 in Brain Endothelial Cells

Matsumura, K., Cao, C., OZAKI, M., Morii, H., Nakadate, K., & Watanabe, Y. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb08338.x · Cited by 15 · see citing works

Effect of transection of various branches of the vagus nerve on lipopolysaccharide-induced synthesis of corticotropin-releasing hormone mRNA in the paraventricular nuclei of rat hypothalamus

Sergeev, V. G., & Akmaev, I. G. (2000) · Bulletin of Experimental Biology and Medicine · doi:10.1007/bf02682111 · Cited by 3 · see citing works

Untitled work

(2000) · doi:10.1002/1096-9861(20001204)428:1

The microbiome: a key regulator of stress and neuroinflammation

Rea, K., Dinan, T. G., & Cryan, J. F. (2016) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.03.001 · Cited by 508 · see citing works

Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection

Silverman, M. N., Pearce, B. D., Biron, C. A., & Miller, A. H. (2005) · Viral Immunology · doi:10.1089/vim.2005.18.41 · Cited by 506 · see citing works

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.08.026 · Cited by 443 · see citing works

The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain

Bellavance, M.-A., & Rivest, S. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00136 · Cited by 419 · see citing works

Mood and gut feelings

Forsythe, P., Sudo, N., Dinan, T., Taylor, V. H., & Bienenstock, J. (2010) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2009.05.058 · Cited by 429 · see citing works

Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome

Cruz-Pereira, J. S., Rea, K., Nolan, Y. M., O'Leary, O. F., Dinan, T. G., & Cryan, J. F. (2020) · Annual Review of Psychology · doi:10.1146/annurev-psych-122216-011613 · Cited by 320 · see citing works

Fever, fever patterns and diseases called “fever”—A review

Ogoina, D. (2011) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2011.05.002 · Cited by 305 · see citing works

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

Skelly, D., Hennessy, E., Dansereau, M., & Cunningham, C. M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069123 · Cited by 278 · see citing works

Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms

Teeling, J. L., & Perry, V. H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.07.031 · Cited by 251 · see citing works

Reflex control of inflammation by sympathetic nerves, not the vagus

Martelli, D., Yao, S. T., McKinley, M. J., & McAllen, R. M. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2013.268573 · Cited by 241 · see citing works

Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment

Mazza, M. G., Palladini, M., Poletti, S., & Benedetti, F. (2022) · CNS Drugs · doi:10.1007/s40263-022-00931-3 · Cited by 233 · see citing works

Neural regulation of inflammation: no neural connection from the vagus to splenic sympathetic neurons

Bratton, B. O., Martelli, D., McKinley, M. J., Trevaks, D., Anderson, C. R., & McAllen, R. M. (2012) · Experimental Physiology · doi:10.1113/expphysiol.2011.061531 · Cited by 206 · see citing works

Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration: The role of vitamin E

Ambrogini, P., Torquato, P., Bartolini, D., Albertini, M. C., Lattanzi, D., Palma, M. D., Marinelli, R., Betti, M., Minelli, A., Cuppini, R., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2019.01.026 · Cited by 186 · see citing works

Regulatory and Mechanistic Actions of Glucocorticoids on T and Inflammatory Cells

Liberman, A. C., Budziñski, M. L., Sokn, C., Gobbini, R. P., Steininger, A., & ARZT, E. S. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00235 · Cited by 185 · see citing works

Mechanisms of Fever Production and Lysis: Lessons from Experimental LPS Fever

Roth, J., & Blatteis, C. M. (2014) · Comprehensive physiology · doi:10.1002/cphy.c130033 · Cited by 196 · see citing works

Inflammatory mediators in major depression and bipolar disorder

Poletti, S., Mazza, M. G., & Benedetti, F. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02921-z · Cited by 179 · see citing works

Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

Gárate, I., García‐Bueno, B., Madrigal, J. L. M., Bravo, L., Berrocoso, E., Caso, J. R., Micó, J. A., & Leza, J. C. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-151 · Cited by 163 · see citing works

Sensory circumventricular organs in health and disease

Sisó, S., Jeffrey, M., & González, L. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0743-5 · Cited by 158 · see citing works

Idiopathic Cystitis in Domestic Cats—Beyond the Lower Urinary Tract

Buffington, C. A. T. (2011) · Journal of Veterinary Internal Medicine · doi:10.1111/j.1939-1676.2011.0732.x · Cited by 137 · see citing works

Role of IL-1 and TNF in the brain: Twenty years of progress on a Dr. Jekyll/Mr. Hyde duality of the innate immune system

Gosselin, D., & Rivest, S. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.12.004 · Cited by 130 · see citing works

Infection, immunity and the neuroendocrine response

Borghetti, P., Saleri, R., Mocchegiani, E., Corradi, A., & Martelli, P. R. (2009) · Veterinary Immunology and Immunopathology · doi:10.1016/j.vetimm.2009.01.013 · Cited by 128 · see citing works

Mechanisms of Neuroimmunity and Neurodegeneration Associated with HIV-1 Infection and AIDS

Kaul, M., & Lipton, S. A. (2006) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-006-9011-9 · Cited by 123 · see citing works

Hormones, immune response, and pregnancy in healthy women and SLE patients.

Zen, M., Ghirardello, A., Iaccarino, L., Tonon, M., Campana, C., Arienti, S., Rampudda, M., Canova, M., & Doria, A. (2010) · Swiss Medical Weekly · doi:10.4414/smw.2010.12597 · Cited by 114 · see citing works

MyD88 signaling in brain endothelial cells is essential for the neuronal activity and glucocorticoid release during systemic inflammation

Gosselin, D., & Rivest, S. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002122 · Cited by 109 · see citing works

Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?

Tomljenovic, L., & Shaw, C. A. (2011) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2011.08.008 · Cited by 114 · see citing works

The role of adrenal gland microenvironment in the HPA axis function and dysfunction during sepsis

Kanczkowski, W., Sue, M., Zacharowski, K., Reincke, M., & Bornstein, S. R. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.12.019 · Cited by 101 · see citing works

The effects of ozone exposure and associated injury mechanisms on the central nervous system

Martínez-Lazcano, J. C., González-Guevara, E., del Carmen Rubio, M., Franco-Pérez, J., Custodio, V., Hernández-Cerón, M., Livera, C., & Paz, C. (2013) · Reviews in the Neurosciences · doi:10.1515/revneuro-2012-0084 · Cited by 94 · see citing works

Signals generating anorexia during acute illness

Langhans, W. (2007) · Proceedings of The Nutrition Society · doi:10.1017/s0029665107005587 · Cited by 92 · see citing works

Molecular and cellular immune mediators of neuroprotection

Turrin, N. P., & Rivest, S. (2006) · Molecular Neurobiology · doi:10.1385/mn:34:3:221 · Cited by 85 · see citing works

HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis

Kaul, M. (2007) · Frontiers in bioscience · doi:10.2741/2860 · Cited by 82 · see citing works

TRPV1 is crucial for proinflammatory STAT3 signaling and thermoregulation-associated pathways in the brain during inflammation

Yoshida, A., Furube, E., Mannari, T., Takayama, Y., Kittaka, H., Tominaga, M., & Miyata, S. (2016) · Scientific Reports · doi:10.1038/srep26088 · Cited by 77 · see citing works

Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

Skelly, D. T., Hennessy, E., Dansereau, M.-A., & Cunningham, C. (2013) · PLoS ONE · doi:10.1371/annotation/90c76048-2edd-4315-8404-4d9d8cbd411e · Cited by 77 · see citing works

Molecular Aspects of Fever and Hyperthermia

Roth, J., Rummel, C. D., Barth, S. W., Gerstberger, R., & Hübschle, T. (2006) · Neurologic Clinics · doi:10.1016/j.ncl.2006.03.004 · Cited by 74 · see citing works

Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli

Blais, V., Turrin, N. P., & Rivest, S. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03480.x · Cited by 72 · see citing works

Immune‐Neuroendocrine Interactions and Autoimmune Diseases

Jara, L. J., Navarro, C., Medina, G., Lastra, O. L. V., & Blanco, F. (2006) · Journal of Immunology Research · doi:10.1080/17402520600877059 · Cited by 71 · see citing works

The Environmental Pollutant Tributyltin Chloride Disrupts the Hypothalamic-Pituitary-Adrenal Axis at Different Levels in Female Rats

Merlo, E., Podratz, P. L., Sena, G. C., de Araújo, J. F. P., Freitas‐Lima, L. C., Alves, I. S. S., da Gama-de-Souza, L. N., Pelição, R., Rodrigues, L. C. M., Brandão, P. A. A., et al. (2016) · Endocrinology · doi:10.1210/en.2015-1896 · Cited by 71 · see citing works

Air pollution alters brain and pituitary endothelin-1 and inducible nitric oxide synthase gene expression

Thomson, E. M., Kumarathasan, P., Calderón‐Garcidueñas, L., & Vincent, R. (2007) · Environmental Research · doi:10.1016/j.envres.2007.06.005 · Cited by 67 · see citing works

Is there a relation between extremely low frequency magnetic field exposure, inflammation and neurodegenerative diseases? A review of in vivo and in vitro experimental evidence

Mattsson, M., & Simkó, M. (2012) · Toxicology · doi:10.1016/j.tox.2012.06.011 · Cited by 65 · see citing works

The neuroendocrine control of the innate immune system in health and brain diseases

Bellavance, M., & Rivest, S. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2012.01129.x · Cited by 60 · see citing works

Visceral brain–body information transfer

Cameron, O. G. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.010 · Cited by 58 · see citing works

Endogenous antipyretics

Roth, J. (2006) · Clinica Chimica Acta · doi:10.1016/j.cca.2006.02.013 · Cited by 57 · see citing works

Adrenal Gland Microenvironment and Its Involvement in the Regulation of Stress-Induced Hormone Secretion during Sepsis

Kanczkowski, W., Sue, M., & Bornstein, S. R. (2016) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00156 · Cited by 55 · see citing works

A new look on brain mechanisms of acute illness anorexia

Asarian, L., & Langhans, W. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.04.009 · Cited by 51 · see citing works

ARDS associated acute brain injury: from the lung to the brain

Ziaka, M., & Exadaktylos, A. K. (2022) · European journal of medical research · doi:10.1186/s40001-022-00780-2 · Cited by 50 · see citing works

Neurobiology of cancer: Interactions between nervous, endocrine and immune systems as a base for monitoring and modulating the tumorigenesis by the brain

Mravec, B., Gidron, Y., & Hulín, I. (2007) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2007.12.002 · Cited by 47 · see citing works

Molecular Aspects of Fever and Hyperthermia

Roth, J., Rummel, C. D., Barth, S. W., Gerstberger, R., & Hübschle, T. (2009) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2009.02.005 · Cited by 48 · see citing works

A Role for Brain Cyclooxygenase‐2 and Prostaglandin‐E2 in Migraine: Effects of Nitroglycerin

Tassorelli, C., Greco, R., Armentero, M., Blandini, F., Sandrini, G., & Nappi, G. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(07)82020-4 · Cited by 45 · see citing works

Postnatal programming of the innate immune response

Galic, M. A., Spencer, S. J., Mouihate, A., & Pittman, Q. J. (2009) · Integrative and Comparative Biology · doi:10.1093/icb/icp025 · Cited by 44 · see citing works

Mechanisms of Neurologic Failure in Critical Illness

Pustavoitau, A., & Stevens, R. D. (2008) · Critical Care Clinics · doi:10.1016/j.ccc.2007.11.004 · Cited by 44 · see citing works

The hypothalamic–pituitary–adrenal axis in critical illness

Venkataraman, S., Munoz, R., Cândido, C., & Witchel, S. (2007) · Reviews in Endocrine & Metabolic Disorders · doi:10.1007/s11154-007-9058-9 · Cited by 23 · see citing works

Research Progress on Main Symptoms of Novel Coronavirus Pneumonia Improved by Traditional Chinese Medicine

Luo, C., Ma, L., Liu, H., Liao, W., Xu, R., Ci, Z., Lin, J., Han, L., & Zhang, D. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.556885 · Cited by 43 · see citing works

Autoimmune diseases and their relation with immunological, neurological and endocrinological axes

Coronel-Restrepo, N., Posso‐Osorio, I., Naranjo-Escobar, J., & Tobón, G. J. (2017) · Autoimmunity Reviews · doi:10.1016/j.autrev.2017.05.002 · Cited by 42 · see citing works

Toll-Like Receptors in Endocrine Disease and Diabetes

Kanczkowski, W., Ziegler, C., Zacharowski, K. D., & Bornstein, S. (2008) · NeuroImmunoModulation · doi:10.1159/000135624 · Cited by 39 · see citing works

α-Tocopherol and Hippocampal Neural Plasticity in Physiological and Pathological Conditions

Ambrogini, P., Betti, M., Galati, C., Palma, M. D., Lattanzi, D., Savelli, D., Galli, F., Cuppini, R., & Minelli, A. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122107 · Cited by 38 · see citing works

The interface between cholinergic pathways and the immune system and its relevance to arthritis

McAllen, R. M., Cook, A. D., Khiew, H. W., Martelli, D., & Hamilton, J. A. (2015) · Arthritis Research & Therapy · doi:10.1186/s13075-015-0597-2 · Cited by 37 · see citing works

The social environment and IL-6 in rats and humans

Saxton, K. B., John‐Henderson, N. A., Reid, M., & Francis, D. D. (2011) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2011.05.010 · Cited by 38 · see citing works

VEGF ‐dependent continuous angiogenesis in the median eminence of adult mice

Morita, S., Ukai, S., & Miyata, S. (2012) · European Journal of Neuroscience · doi:10.1111/ejn.12047 · Cited by 36 · see citing works

A clinical and pathological description of 320 cases of naturally acquired Babesia rossi infection in dogs

Leisewitz, A. L., Goddard, A., Clift, S. J., Thompson, P. N., de Gier, J., Engelshoven, J. M. A. J. A. J. V., & Schoeman, J. P. (2019) · Veterinary Parasitology · doi:10.1016/j.vetpar.2019.06.005 · Cited by 37 · see citing works

Fever and Antipyretic Supported by Traditional Chinese Medicine: A Multi-Pathway Regulation

Ma, L.-L., Liu, H., Luo, C., He, Y., Wang, F., Huang, H., Han, L., Yang, M., Xu, R., & Zhang, D. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.583279 · Cited by 35 · see citing works

Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity

Liu, Y., Xie, X., Xia, L., Lv, H., Lou, F., Ren, Y., He, Z., & Luo, X.-G. (2017) · Journal of Neuroinflammation · doi:10.1186/s12974-017-0994-3 · Cited by 33 · see citing works

Central and peripheral neuroimmune responses: hyporesponsiveness during pregnancy

Spencer, S. J., Mouihate, A., Galic, M. A., & Pittman, Q. J. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.144006 · Cited by 31 · see citing works

Temperature Regulation and the Pathogenesis of Fever

Sajadi, M. M., & Mackowiak, P. A. (2015) · Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases · doi:10.1016/b978-1-4557-4801-3.00055-2 · Cited by 30 · see citing works

The behavioral study on the interactive aggravation between pruritus and depression

Wang, X., Yang, G., Bai, Y., Feng, Y., & Li, H. (2018) · Brain and Behavior · doi:10.1002/brb3.964 · Cited by 29 · see citing works

Prostaglandin mediates endotoxaemia‐induced hypophagia by activation of pro‐opiomelanocortin and corticotrophin‐releasing factor neurons in rats

Rorato, R. C., Menezes, A. M., Giusti‐Paiva, A., de Castro, M., Antunes‐Rodrigues, J., & Elias, L. L. K. (2008) · Experimental Physiology · doi:10.1113/expphysiol.2008.045435 · Cited by 28 · see citing works

Do pathogen exposure and innate immunity cause brain diseases?

Simard, A. R., & Rivest, S. (2005) · Neurological Research · doi:10.1179/016164105x49526 · Cited by 30 · see citing works

Irradiation Does Not Compromise or Exacerbate the Innate Immune Response in the Brains of Mice That Were Transplanted with Bone Marrow Stem Cells

Turrin, N. P., Plante, M.-M., Lessard, M., & Rivest, S. (2007) · Stem Cells · doi:10.1634/stemcells.2007-0508 · Cited by 27 · see citing works

Cytokine expression, glucocorticoid and growth hormone changes after porcine reproductive and respiratory syndrome virus (PRRSV-1) infection in vaccinated and unvaccinated naturally exposed pigs

Borghetti, P., Saleri, R., Ferrari, L., Morganti, M. M., Angelis, E. D., Franceschi, V., Bottarelli, E., & Martelli, P. R. (2010) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2010.06.004 · Cited by 27 · see citing works

Neural–endocrine–immune complex in the central modulation of tumorigenesis: Facts, assumptions, and hypotheses

Mravec, B., Gidron, Y., Kukanova, B., Bízik, J., Kiss, A., & Hulín, I. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.07.003 · Cited by 26 · see citing works

Impact of Thiamine Deficiency on T-cell Dependent and T-cell Independent Antibody Production in Lake Trout

Ottinger, C. A., Honeyfield, D. C., Densmore, C. L., & Iwanowicz, L. R. (2012) · Journal of Aquatic Animal Health · doi:10.1080/08997659.2012.713890 · Cited by 25 · see citing works

Mechanisms of Fever Production and Lysis: Lessons from Experimental LPS Fever

Roth, J., & Blatteis, C. M. (2014) · Comprehensive physiology · doi:10.1002/j.2040-4603.2014.tb00582.x · Cited by 24 · see citing works

Autoimmune Diseases in Patients with Cushing’s Syndrome after Resolution of Hypercortisolism: Case Reports and Literature Review

Petramala, L., Olmati, F., Conforti, M. G., Concistrè, A., Bisogni, V., Alfieri, N., Iannucci, G., Toma, G. D., & Letizia, C. (2018) · International Journal of Endocrinology · doi:10.1155/2018/1464967 · Cited by 23 · see citing works

Neuropeptide W Attenuates Oxidative Multi-Organ Injury in Rats Induced with Intra-Abdominal Sepsis

Atıcı, A. E., Tamer, S. A., Levent, H. N., Eyüboğlu, İ. P., Ercan, F., Akkіprіk, M., & Yeğen, B. Ç. (2021) · Inflammation · doi:10.1007/s10753-021-01545-5 · Cited by 18 · see citing works

Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis – Influence on microglial function

Danis, B., van Rikxoort, M., Kretschmann, A., Zhang, J., Godard, P., Andonovic, L., Siegel, F., Niehusmann, P., Hanon, É., Delev, D., et al. (2016) · Scientific Reports · doi:10.1038/srep33943 · Cited by 18 · see citing works

α-MSH and γ-MSH modulate early release of hypothalamic PGE2 and NO induced by IL-1β differently

Cragnolini, A. B., Caruso, C. M., Lasaga, M., & Scimonelli, T. N. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.09.034 · Cited by 16 · see citing works

Changes in pericytic expression of NG2 and PDGFRB and vascular permeability in the sensory circumventricular organs of adult mouse by osmotic stimulation

Morita, S., Hourai, A., & Miyata, S. (2013) · Cell Biochemistry and Function · doi:10.1002/cbf.2971 · Cited by 14 · see citing works

Microbial and Host Metabolites at the Backstage of Fever: Current Knowledge about the Co-Ordinate Action of Receptors and Molecules Underlying Pathophysiology and Clinical Implications

Santacroce, L., Colella, M., Charitos, I. A., Domenico, M. D., Palmirotta, R., & Jirillo, E. (2023) · Metabolites · doi:10.3390/metabo13030461 · Cited by 18 · see citing works

Pituitary Function During Severe and Life-threatening Illnesses

Gauna, C., den Berghe, G. V., & van der Lely, A. J. (2005) · Pituitary · doi:10.1007/s11102-006-6043-3 · Cited by 14 · see citing works

Tetramethylpyrazine decreases hypothalamic glutamate, hydroxyl radicals and prostaglandin-E2 and has antipyretic effects

Chang, C.-H., Huang, W.-T., Kao, C.-H., Chen, S.-H., & Lin, C. (2013) · Inflammation Research · doi:10.1007/s00011-013-0606-3 · Cited by 12 · see citing works

Peripheral Blood Monocyte Tolerance Alleviates Intraperitoneal Lipopolysaccharides-Induced Neuroinflammation in Rats Via Upregulating the CD200R Expression

Xia, L., Xie, X., Liu, Y., & Luo, X. (2017) · Neurochemical Research · doi:10.1007/s11064-017-2334-5 · Cited by 10 · see citing works

Thermal dysregulation in patients with multiple sclerosis during SARS-CoV-2 infection. The potential therapeutic role of exercise

Razi, O., Tartibian, B., Teixeira, A. M., Zamani, N., Govindasamy, K., Suzuki, K., Laher, I., & Zouhal, H. (2022) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2022.103557 · Cited by 10 · see citing works

Fièvre et cancer : éléments de diagnostic pour une prise en charge adaptée

Moussaid, Y., Bertaux, M., Chargari, C., Hélissey, C., Moulec, S. L., Errihani, H. H., & Védrine, L. (2012) · La Revue de Médecine Interne · doi:10.1016/j.revmed.2012.10.368 · Cited by 5 · see citing works

The Hypothalamus is the Central Organ of Immunoregulation

Berczi, I., & Arnason, B. G. W. (2010) · Neuroimmune biology · doi:10.1016/s1567-7443(10)70006-5 · Cited by 3 · see citing works

Neuroinflammation and Excitotoxicity in Neurobiology of HIV-1 Infection and AIDS: Targets for Neuroprotection

Kaul, M., & Lipton, S. A. (2007) · Springer eBooks · doi:10.1007/978-0-387-70830-0_13 · Cited by 3 · see citing works

Retrospective Analysis of Fever in Pediatric Age: Our Experience over the Last 5 Years

Valenzise, M., D’Amico, F., Barbera, G. L., Cassone, C. M., Patafi, S., Lombardo, F., Aversa, T., Wasniewska, M. G., Salzano, G., & Morace, C. (2024) · Children · doi:10.3390/children11050539 · Cited by 2 · see citing works

Neuro-Endocrine-Immune Interactions in Maintaining the Integrity of the Body

Drela, N. (2024) · Integrated science · doi:10.1007/978-3-031-73061-0_2 · Cited by 3 · see citing works

Sickness behaviors in chronic cholestasis

Aspinall, A. I., & Adams, D. (2005) · Hepatology · doi:10.1002/hep.21032 · Cited by 2 · see citing works

Etiopathogenesis of Feline Idiopathic Cystitis

Westropp, J. L., & Buffington, C. A. T. (2006) · Elsevier eBooks · doi:10.1016/b0-72-160423-4/50050-0 · Cited by 1 · see citing works

Adaptive (Hypothalamic) and Innate Immunoregulation

Berczi, I., Quintanar‐Stephano, A., & Kovács, K. (2011) · Advances in Neuroimmune Biology · doi:10.3233/nib-2011-028

Relação entre o padrão de citocinas secretadas por células de microglia ativadas in vitro e a geração de células T

Brandão, W. N. (2013) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2013.tde-16092013-160405

Immune System–Neuroendocrine Interactions

Rivest, S. (2009) · Elsevier eBooks · doi:10.1016/b978-008045046-9.01180-3

The Role of Systemic Inflammation in the Development of Equine Laminitis

Tadros, E. M. (2011)

HIV treatment: mechanisms of neurotoxicity and implications for targeted therapy

Lu, Y., & Wu (2012) · Neurobehavioral HIV Medicine · doi:10.2147/nbhiv.s24914

Molecular Neurology of HIV-1 Infection and AIDS

Kaul, M., & Lipton, S. A. (2007) · Elsevier eBooks · doi:10.1016/b978-012369509-3.50036-6

Fever: Mediators and Mechanisms

Roth, J. (2017) · Wiley-VCH eBooks · doi:10.1002/9783527692156.ch33

NEUROENDOCRINE ROLE IN INTERSTITIAL CYSTITIS AND CHRONIC PELVIC PAIN IN WOMEN

Buffington, C. A. T. (2008) · Elsevier eBooks · doi:10.1016/b978-1-4160-2339-5.50139-7

The role of inflammatory signaling in comorbid depression and epilepsy

Tchekalarova, J. D., Atanasova, D., & Lazarov, N. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-817935-2.00041-6

Diagnostic and Prognostic Value of Quantitative Computed Tomography Parameters of Adrenal Glands in Patients from Internistled ICU with Sepsis and Septic Shock

Milberg, M., Kindt, A. S. D., Luft, L., Hoffmann, U., Behnes, M., Schoenberg, S. O., & Janssen, S. (2022) · Anatomia · doi:10.3390/anatomia1010003

BIBLIOGRAPHY

(2007) · Elsevier eBooks · doi:10.1016/b978-012373657-4/50008-8

AIDS

Kaul, M. (2014) · Springer eBooks · doi:10.1007/978-1-4614-5836-4_137

Fever: A Brief Overview

Pongen, R. (2023) · International Journal of Science and Research (IJSR) · doi:10.21275/sr23618205728

Immune System–Neuroendocrine Interactions

Rivest, S. (2009) · Elsevier eBooks · doi:10.1016/b978-008045046-9.01180-3

Interactions Between the Immune and Neuroendocrine Systems

Rivest, S. (2010) · Progress in brain research · doi:10.1016/s0079-6123(08)81004-7 · Cited by 106 · see citing works

Signaling the brain in inflammation: the role of endothelial cells

Matsumura, K. (2004) · Frontiers in bioscience · doi:10.2741/1439 · Cited by 87 · see citing works

Prostaglandin E2 in Brain-mediated Illness Responses

Elander, L. (2010) · DiVA (Linkoping University)

Pathway across the blood–brain barrier

Ek, M., Engblom, D., Saha, S., Blomqvist, A. G., Jakobsson, P., & Ericsson‐Dahlstrand, A. (2001) · Nature · doi:10.1038/35068632 · Cited by 347 · see citing works