The DOI matches its Crossref record; 198 of the 198 references it cites were found in a registry or an index.
Adipokines: A link between obesity and cardiovascular disease
Open accessAbstract
Obesity is a risk factor for various cardiovascular diseases including hypertension, atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the microenvironment of adipose tissue and its impact on systemic metabolism have shed light on the pathogenesis of obesity-linked cardiovascular diseases. Adipose tissue functions as an endocrine organ by secreting multiple immune-modulatory proteins known as adipokines. Obesity leads to increased expression of pro-inflammatory adipokines and diminished expression of anti-inflammatory adipokines, resulting in the development of a chronic, low-grade inflammatory state. This adipokine imbalance is thought to be a key event in promoting both systemic metabolic dysfunction and cardiovascular disease. This review will focus on the adipose tissue microenvironment and the role of adipokines in modulating systemic inflammatory responses that contribute to cardiovascular disease.
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Cites
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Cited by
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Metadata
- Authors
- Nakamura, K., Fuster, J. J., & Walsh, K.
- Venue
- Journal of Cardiology
- Publisher
- Elsevier BV
- Published
- 2014-04
- Volume
- 63
- Issue
- 4
- Pages
- 250-259
- ISSN
- 0914-5087 (ISSN-L)
- OpenAlex
- W1993169389
- Cited by
- 578
- References
- 198
- FWCI
- 21.62
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
