Cited by 127Cardiovascular and exercise physiologyPhysical Activity and HealthLipoproteins and Cardiovascular Health

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Aerobic exercise and lipids and lipoproteins in men: a meta-analysis of randomized controlled trials

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Kelley, George A., Kelley, Kristi S.·2006·The Journal of Men's Health & Gender

DOI 10.1016/j.jmhg.2005.09.003PMC PMC2475654

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Abstract

BACKGROUND: Aerobic exercise is recommended for improving lipoprotein and lipid levels which at less than their optimal levels are risk factors for cardiovascular disease. Evidence seems lacking for the effectiveness of exercise in reducing these levels, possibly due to small sizes in studies. We concluded a meta-analysis of the studies to examine the effects of aerobic exercise on lipids and lipoproteins in adult men. METHODS: Studies were retrieved via computerized literature searches, cross-referencing from retrieved articles, hand-searching, and expert review of our reference list. Inclusion criteria were randomized controlled trials, aerobic exercise ≥8 weeks, adult men ≥18 years of age, studies published in journal, dissertation, or master's thesis format, studies published in the English-language between January 1, 1955 and January 1, 2003, and assessment of one or more of the following lipids and lipoproteins: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDLC), and triglycerides (TG). All coding was conducted by both authors, independent of each other. Discrepancies were resolved by consensus. RESULTS: Forty-nine randomized controlled trials representing up to 67 outcomes from 2,990 men (1,741 exercise, 1,249 control) were pooled for analysis. Using random-effects modeling, statistically significant improvements were observed for TC, HDL-C and TG, and a trend for decreases was observed for LDL-C. Changes were equivalent to improvements of 2% for TC and HDL-C, 3% of LDL-C, and 9% for TG. CONCLUSIONS: Aerobic exercise reduces TC and TG and increases HDL-C in men 18 years of age and older.

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Authors: Kelley, G. A., & Kelley, K. S.
Affiliations: West Virginia University (US)
ORCID: Kelley, George A.
Kelley, Kristi S.
Venue: The Journal of Men's Health & Gender
Publisher: SAGE Publications
Published: 2006-03
Volume: 3
Issue: 1
Pages: 61-70
ISSN: 1571-8913 (ISSN-L)
DOI: 10.1016/j.jmhg.2005.09.003
PMC: PMC2475654
OpenAlex: W2045752222
Cited by: 127
References: 93
Citations by year: 2026: 6 · 2025: 3 · 2024: 8 · 2023: 5 · 2022: 8 · 2021: 7 · 2020: 6 · 2019: 9 · 2018: 9 · 2017: 5 · 2016: 3 · 2015: 4 · 2014: 10 · 2013: 8 · 2012: 5
FWCI: 0.62
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: The Journal of Men s Health and Gender (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health
National Heart, Lung, and Blood Institute (R01HL069802)
Topics: Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Keywords: aerobic exercise, lipids, lipoproteins, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, cardiovascular risk, men, exercise intervention

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Aerobic exercise and lipids and lipoproteins in men: a meta-analysis of randomized controlled trials

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