The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS-CoV-2 agents?
Open accessAbstract
Co-infection has been reported in patients with severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome, but there is limited knowledge on co-infection among patients with coronavirus disease 2019 (COVID-19). The prevalence of co-infection was variable among COVID-19 patients in different studies, however, it could be up to 50% among non-survivors. Co-pathogens included bacteria, such as Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae, Mycoplasma pneumoniae, Chlamydia pneumonia, Legionella pneumophila and Acinetobacter baumannii; Candida species and Aspergillus flavus; and viruses such as influenza, coronavirus, rhinovirus/enterovirus, parainfluenza, metapneumovirus, influenza B virus, and human immunodeficiency virus. Influenza A was one of the most common co-infective viruses, which may have caused initial false-negative results of real-time reverse-transcriptase polymerase chain reaction for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Laboratory and imaging findings alone cannot help distinguish co-infection from SARS-CoV-2 infection. Newly developed syndromic multiplex panels that incorporate SARS-CoV-2 may facilitate the early detection of co-infection among COVID-19 patients. By contrast, clinicians cannot rule out SARS-CoV-2 infection by ruling in other respiratory pathogens through old syndromic multiplex panels at this stage of the COVID-19 pandemic. Therefore, clinicians must have a high index of suspicion for coinfection among COVID-19 patients. Clinicians can neither rule out other co-infections caused by respiratory pathogens by diagnosing SARS-CoV-2 infection nor rule out COVID-19 by detection of non-SARS-CoV-2 respiratory pathogens. After recognizing the possible pathogens causing co-infection among COVID-19 patients, appropriate antimicrobial agents can be recommended.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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Clinical characteristics of coronavirus disease 2019 in China
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La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
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Self-citationMetlay, J. P., Waterer, G. W., Long, A. C., Anzueto, A., Brozek, J., Crothers, K., Cooley, L. A., Dean, N. C., Fine, M. J., Flanders, S. A., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201908-1581st · Cited by 3,657
Cited by
Metlay, J. P., Waterer, G. W., Long, A. C., Anzueto, A., Brozek, J., Crothers, K., Cooley, L. A., Dean, N. C., Fine, M. J., Flanders, S. A., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201908-1581st · Cited by 3,657
Increased antimicrobial resistance during the COVID-19 pandemic
Lai, C.-C., Chen, S.-Y., Ko, W.-C., & Hsueh, P.-R. (2021) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2021.106324 · Cited by 436
Self-citationThe role of co-infections and secondary infections in patients with COVID-19
Feldman, C., & Anderson, R. (2021) · Pneumonia · doi:10.1186/s41479-021-00083-w · Cited by 319
Al-Shaarani, A. A. Q. A., & Pecoraro, L. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1428415 · Cited by 50
Metadata
- Authors
- Lai, C.-C., Wang, C.-Y., & Hsueh, P.-R.
- Venue
- Journal of Microbiology, Immunology and Infection
- Publisher
- Elsevier BV
- Published
- 2020-08
- Volume
- 53
- Issue
- 4
- Pages
- 505-512
- ISSN
- 1684-1182 (ISSN-L)
- OpenAlex
- W3026446975
- Cited by
- 489
- References
- 43
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- gold
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