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Cited by 276

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Effect of Age and Sex on Heart Rate Variability in Healthy Subjects

Zhang, John·2007·Journal of Manipulative and Physiological Therapeutics

Abstract

OBJECTIVE: The study aimed to investigate the effect of age and sex on the heart rate variability (HRV) analysis and to explore the normal range of HRV in different age and sex groups for potential health care applications. METHOD: Baseline HRV, age, and sex data were collected from 470 subjects without cardiovascular conditions. Short-term HRV was recorded using Biocom Active ECG units (Biocom, Seattle, Wash). Subjects were divided by age into 10-year intervals and by sex for HRV analysis. RESULTS: Total power, representing the overall autonomic activity, decreased consistently from the age groups 10+ to 80+ years (P < .001). Both the low frequency (sympathetic activity) and high frequency (parasympathetic activity) declined (P < .05) as age increased. Sex had a significant effect on heart rate, R-R interval, high frequency, normalized low frequency, normalized high frequency, and low frequency-high frequency ratio. Sex did not seem to affect the SD of the normal-to-normal heartbeats and total power (P > .05) despite the significant heart rate changes (P < .05). CONCLUSION: This study demonstrated that age had a greater impact on HRV than sex. The older age group had consistently lower HRV than younger people. The values generated in this study may be useful in health care settings to determine abnormal ranges of HRV under different clinical and experimental conditions.

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Crossref · 10.1016/j.jmpt.2007.04.001

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Metadata

Authors
Zhang, J.
Venue
Journal of Manipulative and Physiological Therapeutics
Publisher
Elsevier BV
Published
2007-06
Volume
30
Issue
5
Pages
374-379
ISSN
0161-4754 (ISSN-L)
OpenAlex
W2071427714
Cited by
276
References
2
FWCI
3.89
Type
journal article
Language
en
Open access
closed

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