CoChat
Sign Up
Cited by 79Multiple Sclerosis Research StudiesGenetic Associations and EpidemiologyPsoriasis: Treatment and Pathogenesis

Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis

Nischwitz, Sandra, Cepok, Sabine, Kroner, Antje, Wolf, Christiane, Knop, Matthias, Müller-Sarnowski, Felix, Pfister, Hildegard, Roeske, Darina +8 more·2010·Journal of Neuroimmunology
DOI 10.1016/j.jneuroim.2010.06.003
Open this paper in CoChat — free account

Abstract

In a genome wide association study consisting of 592 German multiple sclerosis (MS) patients and 825 controls we were able to replicate the association of the HLA region with MS independently of previous case control studies. No SNPs outside the HLA region reached a genome wide level of significance. Nevertheless, we found suggestive evidence for an association of MS with variants in two new genes, the VAV2 gene and the gene for ZNF433.

Integrity signals

Registry

Crossref · 10.1016/j.jneuroim.2010.06.003

Cites

1 of 1 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • By 2011, common variants in 26 genomic loci had been associated with multiple sclerosis risk and independently replicated.

    “by 2011, common variants in 26 genomic loci had been associated with MS risk and independently replicated”

    From Genome‐wide association studies of multiple sclerosis (2018) · cites this paper as [39]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Nischwitz, S., Cepok, S., Kroner, A., Wolf, C., Knop, M., Müller-Sarnowski, F., Pfister, H., Roeske, D., Rieckmann, P., Hemmer, B., Ising, M., Uhr, M., Bettecken, T., Holsboer, F., Müller-Myhsok, B., & Weber, F.
Affiliations
  • Max Planck Institute of Psychiatry (DE)
  • Technical University of Munich (DE)
  • University of Würzburg (DE)
  • Max Planck Society (DE)
  • University of British Columbia Hospital (CA)
Corresponding author
Weber, Frank
ORCID
Venue
Journal of Neuroimmunology
Publisher
Elsevier BV
Published
2010-10
Volume
227
Issue
1-2
Pages
162-166
ISSN
0165-5728 (ISSN-L)
DOI
10.1016/j.jneuroim.2010.06.003
OpenAlex
W2032897361
Cited by
79
References
1
Citations by year
2025: 2 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 7 · 2019: 9 · 2018: 8 · 2017: 2 · 2016: 5 · 2015: 5 · 2014: 8 · 2013: 11 · 2012: 4
FWCI
5.43
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • Journal of Neuroimmunology (publishedVersion)
  • PubMed (publishedVersion)
  • Max Planck Institute for Plasma Physics (submittedVersion)
  • mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) (submittedVersion)
  • OPUS (Augsburg University) (submittedVersion)
Funders
BMBF (KKN-MS, Control-MS).
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
  • Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
Keywords
multiple sclerosis, Vav2, susceptibility genes, HLA region, genetic association, single nucleotide polymorphisms, German population
MeSH terms
Adolescent, Adult, Aged, Female, HLA Antigens, Humans, Male, Middle Aged, Multiple Sclerosis, Repressor Proteins, Case-Control Studies, Zinc Fingers, Genetic Predisposition to Disease, Polymorphism, Single Nucleotide, Proto-Oncogene Proteins c-vav, Genome-Wide Association Study, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review