Mechanisms of action and effects of the administration of Coenzyme Q10 on metabolic syndrome

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Nonalcoholic Fatty Liver Disease

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The antioxidant role of coenzyme Q

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The Inhibition of Mitochondrial Peroxidation by Ubiquinone and Ubiquinol

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Coenzyme Q – Biosynthesis and functions

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Lovastatin decreases coenzyme Q levels in humans.

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NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

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Mitochondrial dysfunction in white adipose tissue

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Evidence of Plasma CoQ10‐Lowering Effect by HMG‐CoA Reductase Inhibitors: A Double‐Blind, Placebo‐Controlled Study

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Insulin Resistance, the Metabolic Syndrome, and Nonalcoholic Fatty Liver Disease

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Clinical aspects of coenzyme Q10: An update

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Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations

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Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials

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Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome

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Co‐Enzyme Q10: A New Drug for Cardiovascular Disease

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Safety assessment of coenzyme Q 10 (CoQ 10 )

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Could inflammatory markers help diagnose nonalcoholic steatohepatitis?

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Coenzyme Q10 in cardiovascular disease

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Coenzyme Q10 Therapy

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The uptake and distribution of coenzyme Q(10)

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Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity

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Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial

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Risk assessment for coenzyme Q10 (Ubiquinone)

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Coenzyme Q10: Absorption, Antioxidative Properties, Determinants, and Plasma Levels

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Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction

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Coenzyme Q10 in essential hypertension

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The effects of coenzyme Q10 administration on glucose homeostasis parameters, lipid profiles, biomarkers of inflammation and oxidative stress in patients with metabolic syndrome

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Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure

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Mitochondrial dysfunction in obesity: potential benefit and mechanism of Co-enzyme Q10 supplementation in metabolic syndrome

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Oral Coenzyme Q10 Supplementation in Patients with Nonalcoholic Fatty Liver Disease: Effects on Serum Vaspin, Chemerin, Pentraxin 3, Insulin Resistance and Oxidative Stress

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Coenzyme Q10: is there a clinical role and a case for measurement?

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The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus

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Mitochondrial development and the influence of its dysfunction during rat adipocyte differentiation

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Effects of CoQ10 Supplementation on Lipid Profiles and Glycemic Control in Patients with Type 2 Diabetes: a randomized, double blind, placebo-controlled trial

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Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet

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A Randomized, Double-Blind, Placebo-Controlled Crossover Study of Coenzyme Q10 Therapy in Hypertensive Patients With the Metabolic Syndrome

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Role of coenzyme Q 10 as an antioxidant and bioenergizer in periodontal diseases

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Anti-oxidative effect of coenzyme Q10

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Nonalcoholic fatty liver disease: The most common cause of abnormal liver enzymes in the U.S. population

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Comparison of the relative bioavailability of different coenzyme Q 10 formulations with a novel solubilizate (Solu™ Q10)

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Coadministration of Coenzyme Q prevents Rosiglitazone-induced adipogenesis in ob/ob mice

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Biological Variation of Coenzyme Q10

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Coenzyme Q10 and Statin Myalgia: What is the Evidence?

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Effects of Coenzyme Q10 Supplementation on Serum Lipoproteins, Plasma Fibrinogen, and Blood Pressure in Patients With Hyperlipidemia and Myocardial Infarction

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Effect of coenzyme Q10 on glycaemic control, oxidative stress and adiponectin in type 2 diabetes.

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The effect of coenzyme Q10 supplementation on metabolic status of type 2 diabetic patients.

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Coenzyme Q as an Antiadipogenic Factor

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Measurement and stability of plasma reduced, oxidized and total coenzyme Q10 in humans

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Ubiquinol reduces gamma glutamyltransferase as a marker of oxidative stress in humans

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Coenzyme Q10 and its effects in the treatment of neurodegenerative diseases

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Correlation between vitamin A, E, coenzyme Q10 and degree of insulin resistance in obese and non-obese subjects

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Coenzyme Q10 depletion and mitochondrial energy disturbances in rejection development in patients after heart transplantation

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Evaluation of the mutagenic potential of ubidecarenone using three short-term assays

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Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders

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Physical activity and COVID-19. The basis for an efficient intervention in times of COVID-19 pandemic

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Key points for the development of antioxidant cocktails to prevent cellular stress and damage caused by reactive oxygen species (ROS) during manned space missions

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Aging-Related Metabolic Dysfunction in the Salivary Gland: A Review of the Literature

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Nutraceuticals-based therapeutic approach: recent advances to combat pathogenesis of Alzheimer’s disease

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Mechanotransduction and Skeletal Muscle Atrophy: The Interplay Between Focal Adhesions and Oxidative Stress

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Coenzyme Q10 ameliorates carbofuran induced hepatotoxicity and nephrotoxicity in wister rats

Hossain, M., Suchi, T. T., Samiha, F., Islam, M. M. M., Tully, F. A., Hasan, J., Rahman, M. A., Shill, M. C., Bepari, A. K., Rahman, G. M. S., et al. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13727 · Cited by 17 · see citing works

Metabolic markers and oxidative stress in children’s obesity pathogenesis

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Expression of reproduction and antioxidant-related genes in crayfish Cherax quadricarinatus fed with dietary feed additives

Shehata, A. I., Alhoshy, M., Wang, T., Wang, J., Wang, R., Dawood, M. A. O., Zaki, M. A., Wang, Y., & Zhang, Z. (2022) · Aquaculture International · doi:10.1007/s10499-021-00816-0 · Cited by 10 · see citing works

Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity

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Free-radical oxidation as a pathogenetic factor of metabolic syndrome

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Effects of COQ10 with vitamin E supplementation on semen quality and seminal plasma parameters of broiler breeder males

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Association between the Serum Coenzyme Q10 Level and Seizure Control in Patients with Drug-Resistant Epilepsy

Liao, W.-C., Huang, C., Hsiao, Y., Sung, P., Fu, T.-F., Chang, A. Y., & Chang, H. H. (2021) · Healthcare · doi:10.3390/healthcare9091118 · Cited by 8 · see citing works

Mechanistic Insights into Antioxidant Interventions Targeting Obesity-Induced Oxidative Stress in the Pathogenesis and Complications of Type 2 Diabetes Mellitus

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Effect of supplementation with the reduced form of coenzyme Q10 on semen quality and antioxidant status in dogs with poor semen quality: Three case studies

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Hemilabile and Redox‐Active Quinone Ligands Unlock sp 3 ‐Rich Couplings in Nickel‐Catalyzed Olefin Carbosulfenylation

Li, Z., Alturaifi, T. M., Cao, Y., Joannou, M. V., Liu, P., & Engle, K. M. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202411870 · Cited by 7 · see citing works

Prospective dietary radical scavengers: Boon in Pharmacokinetics, overcome insulin obstruction via signaling cascade for absorption during impediments in metabolic disorder like Diabetic Mellitus

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Development and Optimization of Antisolvent Cooling Coupled Crystallization Process for Coenzyme Q10

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Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers

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Therapeutic roles of coenzyme Q10 in peripheral nerve injury-induced neurosensory disturbances: Mechanistic insights from injury to recovery

Vachirarojpisan, T., Srivichit, B., Vaseenon, S., Powcharoen, W., & Imerb, N. (2024) · Nutrition Research · doi:10.1016/j.nutres.2024.07.011 · Cited by 3 · see citing works

Hemilabile and Redox‐Active Quinone Ligands Unlock sp3‐Rich Couplings in Nickel‐Catalyzed Olefin Carbosulfenylation

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Integrating supplementation in the management of patients with heart failure: an evidence-based review

Raddysh, M. E., & Delgado, D. (2021) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2021.1999806 · Cited by 3 · see citing works

Substantiation of approaches to the correction of lipid metabolism disorders and non-alcoholic fatty liver disease in children with exogenous obesity

Поварова, О. В., Gorodetskaya, E. A., Kulyak, O. Y., Demyanenko, A. N., Алимова, И. Л., Каленикова, Е. И., & Os, M. (2022) · Obesity and metabolism · doi:10.14341/omet12802 · Cited by 3 · see citing works

The role of coenzyme Q10 in exercise tolerance and muscle strength

Bian, Z., & Wei, L. (2025) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2025.2507746 · Cited by 2 · see citing works

Effect of coenzyme-q10 in the post-curettage against probing depth, relative attachment loss, and bleeding on probing

Anwaristi, A. Y. (2021) · Journal of Syiah Kuala Dentistry Society · doi:10.24815/jds.v5i2.20015 · Cited by 2 · see citing works

In Vitro Antioxidant Effects of Coenzyme Q10 on Cellular Metabolism in Aged Mesenchymal Stem Cells

Ivan, A., Lukinich-Gruia, A. T., Cristea, M. I., Pricop, M.-A., Calma, C. L., Păunescu, A., Tatu, C. A., Găluşcan, A., & Păunescu, V. (2025) · Applied Sciences · doi:10.3390/app15052783 · Cited by 2 · see citing works

Coenzyme Q10 in the pathogenesis and prevention of metabolic and mitochondrial non-communicable diseases

Gvozdjáková, A., Kucharská, J., Sumbalová, Z., Cornélissen, G., Mojto, V., Rausová, Z., & Singh, R. B. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819815-5.00049-5 · Cited by 2 · see citing works

Effects of Coenzyme Q10 Supplementation on Glycemic Control Biomarkers: An Umbrella Review of Meta‐Analyses of Randomised Controlled Trials

Musazadeh, V., Falahatzadeh, M., Mahmoudinezhad, M., shahhosseini, E., Jamali, M., Pam, P., & Shidfar, F. (2026) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.70182 · Cited by 1 · see citing works

Nutraceuticals and the Microbiota–Gut–Brain Axis: A Pathway for Preventing Cognitive Decline

Castillo-Moral, Á., Toda-Ferran, C., Bulló, M., Teichenné, J., & Escoté, X. (2026) · Nutrition Reviews · doi:10.1093/nutrit/nuag017 · Cited by 1 · see citing works

Różne oblicza mitochondrialnego koenzymu Q

Dominiak, K., & Jarmuszkiewicz, W. (2019) · Postępy Biochemii · doi:10.18388/pb.2019_289 · Cited by 1 · see citing works

Appraisal of Recent Developments in Combined Photodynamic Treatment (PDT)/Photobiomodulation (PBM) for Dermal Wound Healing

Padalhin, A. (2022) · Medical Lasers · doi:10.25289/ml.2022.11.1.8 · Cited by 1 · see citing works

Dietary supplements could prevent cardiometabolic syndrome: Are they safe and reliable enough for disease prevention and health promotion?

Télessy, I. G., Buttar, H. S., Wilson, D. W., & Okpala, C. O. R. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1091327 · Cited by 1 · see citing works

The use of ubiquinone to improve the healing of soft and hard jaw tissues – A systematic review

Soares, A. C., Calderipe, C. B., Giorgis, R. D. S., Grave, L. Q., Fogaça, A. C. M., Torriani, M. A., Vasconcelos, A. C. U., & Schuch, L. F. (2024) · Journal of Oral and Maxillofacial Surgery Medicine and Pathology · doi:10.1016/j.ajoms.2024.07.008 · Cited by 1 · see citing works

Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study

Aydin, I., Erişgin, Z., Çınar, E., Barak, M. Z., Tekelioğlu, Y., Usta, M., Mutlu, H. S., & Türkoğlu, İ. (2024) · Drug and Chemical Toxicology · doi:10.1080/01480545.2024.2442660 · Cited by 1 · see citing works

Body Mass and Biochemical Indexes in Obese Children: Changes in Metabolic Syndrome Development

Поварова, О. В. (2023) · Diabetes & Obesity International Journal · doi:10.23880/doij-16000274 · Cited by 1 · see citing works

Coenzyme Q10 (ubiquinone) and brain diseases: Connection with the eye and the body

Pavlović, D. (2021) · Engrami · doi:10.5937/engrami43-32423

Effects of Dietary Coenzyme Q10 on Egg Quality, Yolk Coenzyme Q10 Content, and Antioxidant Capacity in Laying Hens

Nam, G., & Jang, I.-S. (2025) · Brazilian Journal of Poultry Science · doi:10.1590/1806-9061-2025-2096

Ubiquinone is a hysteretic modulator of the NADH:cytochrome b 5 reductase activity of human C b 5 RPreprint

Valério, G. N., Martínez-Costa, Ó. H., Sanchez-Cabeza, C., Cordas, C. M., & Samhan-Arias, A. K. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.14.699433

CoQ0 hysteresis and inhibition of the cytochrome b5 reductase activity of human Cb5R by CoQ0 and CoQ10

Valério, G. N., Martínez-Costa, Ó. H., Sanchez-Cabeza, C., Cordas, C. M., & Samhan-Arias, A. K. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.02.065

Apiol from Parsley Seeds as a Source for the Synthesis of Coenzyme Q 0 Propanoic Acid Conjugates with Amines Featuring Antioxidant Activity

Adaeva, O. I., Demchuk, D. V., Шевченко, О. Г., Semenova, M. N., & Semenov, V. V. (2026) · ACS Omega · doi:10.1021/acsomega.5c09328

Co-enzyme Q10 in Diabetic Neuropathy: Mechanisms of Action and Clinical Evidence

Devhare, L., Kumar, Y. G., Priya, S., Verma, A., Dubey, M., & Aparna, T. N. (2026) · Springer eBooks · doi:10.1007/978-981-95-9326-2_16

Inflammation and oxidative stress as upstream drivers of diabetic retinopathy: Therapeutic opportunities beyond VEGF

Szappanos, Á., Benyó, Z., & Kovács, K. A. (2026) · Advances in Translational Research · doi:10.1556/1661.2026.00010

Comparative study of the bioavailability of two coenzyme Q10 products following single-dose and 3-week oral administration in healthy adults

Pražnikar, Z. J., Mohorko, N., Valenčić, V., Valetič, V., Gmajner, D., Morosetti, M., Orlando, P., & Petelin, A. (2026) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-026-00999-4

Antioxidants improve male broiler breeder semen: A review

Barbarestani, S. Y., & Kastelic, J. P. (2026) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2026.108313

Efficacy of low-dose snake antivenom in severe neurotoxic snake envenoming

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Mitochondrial dysfunction in obesity: potential benefit and mechanism of Co-enzyme Q10 supplementation in metabolic syndrome

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Coenzyme Q10 and Metabolic Syndrome

Hernández‐Camacho, J. D. (2020) · Springer eBooks · doi:10.1007/978-3-030-45642-9_11

Effects of Coenzyme Q10 Supplementation in Women with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease Evaluated by Magnetic Resonance Imaging—Coenzyme Q10 in Metabolic Syndrome and NAFLD

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Beneficial Effect of Coenzyme Q10 on Increased Oxidative and Nitrative Stress and Inflammation and Individual Metabolic Components Developing in a Rat Model of Metabolic Syndrome

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