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The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Central nervous system manifestations of COVID-19: A systematic review

Open access
Asadi-Pooya, Ali A., Simani, Leila·2020·Journal of the Neurological Sciences

Abstract

Objective In this systematic review, we will discuss the evidence on the occurrence of central nervous system (CNS) involvement and neurological manifestations in patients with COVID-19. Methods MEDLINE (accessed from PubMed) and Scopus from December 01, 2019 to March 26, 2020 were systematically searched for related published articles. In both electronic databases, the following search strategy was implemented and these key words (in the title/abstract) were used: “COVID 19” OR “coronavirus” AND “brain” OR “CNS” OR “neurologic”. Results Through the search strategy, we could identify two articles about neurological involvement by COVID-19. One of these publications was a narrative review and the other one was a viewpoint. However, the authors scanned the reference lists of the included studies and could identify multiple references. One study, specifically investigated the neurological manifestations of COVID-19 and could document CNS manifestations in 25% of the patients. Most of the studies investigated the manifestations of COVID-19 in general. Conclusion While neurological manifestations of COVID-19 have not been studied appropriately, it is highly likely that some of these patients, particularly those who suffer from a severe illness, have CNS involvement and neurological manifestations. Precise and targeted documentation of neurological symptoms, detailed clinical, neurological, and electrophysiological investigations of the patients, attempts to isolate SARS-CoV-2 from cerebrospinal fluid, and autopsies of the COVID-19 victims may clarify the role played by this virus in causing neurological manifestations.

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Crossref · 10.1016/j.jns.2020.116832

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Research works printed but not linked: 2

  1. Li, 2020, The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients, J. Med. Virol.
  2. Miró, 2018, Emergency electroencephalogram: Usefulness in the diagnosis of nonconvulsive status epilepticus by the on-call neurologist, Neurología (English Edn), 33, 71, 10.1016/j.nrleng.2016.05.007 · doi:10.1016/j.nrleng.2016.05.007

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Metadata

Authors
Asadi-Pooya, A. A., & Simani, L.
Venue
Journal of the Neurological Sciences
Publisher
Elsevier BV
Published
2020-06
Volume
413
Pages
116832
ISSN
0022-510X (ISSN-L)
OpenAlex
W3016124786
Cited by
774
References
21
FWCI
27.07
Type
journal article
Language
en
Open access
bronze
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)
Funders
Shiraz University of Medical Sciences

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CoChat. (2026). Citation check: Central nervous system manifestations of COVID-19: A systematic review. https://app.cochat.ai/papers/10.1016/j.jns.2020.116832
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Asadi-Pooya, A. A., & Simani, L. (2020). Central nervous system manifestations of COVID-19: A systematic review. Journal of the Neurological Sciences. https://doi.org/10.1016/j.jns.2020.116832

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.