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Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
Open accessAbstract
In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications themselves are not “fit for purpose,” meaning that incomplete reporting of relevant information effectively renders many publications of limited value as instruments to inform policy or clinical and scientific practice1–21.
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“The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research.”
From The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) · cites this paper as [30]
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CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
the CONSORT Group, Schulz, K. F., Altman, D. G., & Moher, D. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-18 · Cited by 13,371
Self-citationCONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials
Schulz, K. F., Altman, D. G., Moher, D., & for the CONSORT Group (2010) · BMJ · doi:10.1136/bmj.c332 · Cited by 9,329
Self-citationMoher, D., Schulz, K. F., & Altman, D. G. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04337-3 · Cited by 5,373
Self-citationMinimum information about a microarray experiment (MIAME)-toward standards for microarray data
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Animal research: Reporting in vivo experiments: The ARRIVE guidelines
Kilkenny, C., Browne, W., Cuthill, I. C., Emerson, M., & Altman, D. G. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.00872.x · Cited by 3,625
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Chalmers, I., & Glasziou, P. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60329-9 · Cited by 2,208
Animal Research: Reporting in vivo Experiments—The ARRIVE Guidelines
Kilkenny, C., Browne, W., Cuthill, I. C., Emerson, M., & Altman, D. G. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.220 · Cited by 2,012
Self-citationGuidance for Developers of Health Research Reporting Guidelines
Moher, D., Schulz, K. F., Simera, I., & Altman, D. G. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000217 · Cited by 1,437
Self-citationCan Animal Models of Disease Reliably Inform Human Studies?
van der Worp, H. B., Howells, D. W., Sena, E. S., Porritt, M. J., Rewell, S., O'Collins, V., & Macleod, M. R. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000245 · Cited by 1,354
Guidelines for the Design and Statistical Analysis of Experiments Using Laboratory Animals
Festing, M. F. W., & Altman, D. G. (2002) · ILAR Journal · doi:10.1093/ilar.43.4.244 · Cited by 1,110
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Research works printed but not linked: 5
- Macleod, 2005, What can systematic review and meta-analysis tell us about the experimental data supporting stroke drug development?, Int J Neuroprot Neuroregener, 1, 201
- Council of Science Editors – Editorial Policy Committee (2008–2009) CSE’s White Paper on promoting integrity in scientific journal publications, 2009 Update. Available: http://www. councilscienceeditors.org/editorial_policies/whitepaper/entire_whitepaper.pdf. Accessed 22 January 2010.
- Committee on publication ethics (COPE). COPE best practice guidelines for journal editors. Available: http://publicationethics.org/files/u2/Best_Practice.pdf. Accessed 22 January 2010.
- Nuffield Council on Bioethics: The Ethics of Research involving Animals (2005) Chapter 15: Discussion and Recommendations; pp 313, paragraph 15.58. Available: http://www.nuffieldbioethics.org/fileLibrary/pdf/RIA_Report_FINAL-opt.pdf. Accessed 26 January 2010.
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Metadata
- Authors
- Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M., & Altman, D. G.
- Affiliations
- National Centre for the Replacement Refinement and Reduction of Animals in Research (GB)
- University of Bristol (GB)
- Imperial College London (GB)
- University of Oxford (GB)
- Corresponding author
- Kilkenny, C.
- Venue
- Osteoarthritis and Cartilage
- Publisher
- Elsevier BV
- Published
- 2012-04
- Volume
- 20
- Issue
- 4
- Pages
- 256-260
- ISSN
- 1063-4584 (ISSN-L)
- OpenAlex
- W2121190453
- Cited by
- 728
- References
- 55
- Citations by year
- 2026: 33 · 2025: 31 · 2024: 41 · 2023: 63 · 2022: 85 · 2021: 87 · 2020: 95 · 2019: 77 · 2018: 63 · 2017: 51 · 2016: 41 · 2015: 33 · 2014: 19 · 2013: 8
- FWCI
- 27.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Osteoarthritis and Cartilage (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Bristol Research (University of Bristol) (acceptedVersion, other-oa)
- Explore Bristol Research (submittedVersion, cc-by)
- Funders
- Wellcome Trust
- British Heart Foundation
- Royal Society
- Parkinson's UK
- Imperial College London
- National Centre for the Replacement, Refinement and Reduction of Animals in Research
- Directorate for Biological Sciences
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- Topics
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Library and Information Sciences › Academic Publishing and Open Access
- Keywords
- ARRIVE guidelines, animal research reporting, reporting quality, open access journals, biomedical research, reporting guidelines, reproducibility
- MeSH terms
- Animals, Animal Husbandry, Data Interpretation, Statistical, Peer Review, Periodicals as Topic, Publishing, Quality Control, Research Design, Guidelines as Topic, Animal Experimentation, Checklist
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