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Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research
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In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of open-access journals has revolutionised the publication process, maximising the availability of research data. Nevertheless, a wealth of evidence shows that across many areas, the reporting of biomedical research is often inadequate, leading to the view that even if the science is sound, in many cases the publications themselves are not “fit for purpose,” meaning that incomplete reporting of relevant information effectively renders many publications of limited value as instruments to inform policy or clinical and scientific practice1–21.
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“The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the reporting of animal research.”
From The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research (2020) · cites this paper as [30]
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Metadata
- Authors
- Kilkenny, C., Browne, W. J., Cuthill, I. C., Emerson, M., & Altman, D. G.
- Affiliations
- National Centre for the Replacement Refinement and Reduction of Animals in Research (GB)
- University of Bristol (GB)
- Imperial College London (GB)
- University of Oxford (GB)
- Corresponding author
- Kilkenny, C.
- Venue
- Osteoarthritis and Cartilage
- Publisher
- Elsevier BV
- Published
- 2012-04
- Volume
- 20
- Issue
- 4
- Pages
- 256-260
- ISSN
- 1063-4584 (ISSN-L)
- OpenAlex
- W2121190453
- Cited by
- 728
- References
- 55
- Citations by year
- 2026: 33 · 2025: 31 · 2024: 41 · 2023: 63 · 2022: 85 · 2021: 87 · 2020: 95 · 2019: 77 · 2018: 63 · 2017: 51 · 2016: 41 · 2015: 33 · 2014: 19 · 2013: 8
- FWCI
- 27.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Osteoarthritis and Cartilage (publishedVersion, other-oa)
- PubMed (publishedVersion)
- Bristol Research (University of Bristol) (acceptedVersion, other-oa)
- Explore Bristol Research (submittedVersion, cc-by)
- Funders
- Wellcome Trust
- British Heart Foundation
- Royal Society
- Parkinson's UK
- Imperial College London
- National Centre for the Replacement, Refinement and Reduction of Animals in Research
- Directorate for Biological Sciences
- Medical Research Council
- Biotechnology and Biological Sciences Research Council
- Topics
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Library and Information Sciences › Academic Publishing and Open Access
- Keywords
- ARRIVE guidelines, animal research reporting, reporting quality, open access journals, biomedical research, reporting guidelines, reproducibility
- MeSH terms
- Animals, Animal Husbandry, Data Interpretation, Statistical, Peer Review, Periodicals as Topic, Publishing, Quality Control, Research Design, Guidelines as Topic, Animal Experimentation, Checklist
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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