Cited by 24Obsessive-Compulsive Spectrum DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPerfectionism, Procrastination, Anxiety Studies

Intolerance of uncertainty in hoarding disorder

Open access
Castriotta, Natalie, Dozier, Mary E., Taylor, Charles T., Mayes, Tina, Ayers, Catherine R.·2019·Journal of Obsessive-Compulsive and Related Disorders

Abstract

Background: Intolerance of uncertainty (IU) has been proposed as a transdiagnostic risk and maintenance factor underlying various forms of psychopathology. Few studies, however, have examined IU in hoarding disorder (HD)—a condition characterized by excessive urges to acquire and difficulties discarding possessions—core symptoms that may be fueled by inflated IU. We examined cross-sectional relationships between IU and different symptom facets of HD, controlling for anxiety and depression severity, and explored whether pre-treatment levels of IU predicted response to exposure-based treatment for HD. Method: Fifty-seven individuals seeking treatment for HD completed baseline measures of hoarding symptoms, IU, anxiety and depression. Participants then completed 26 sessions of group exposure-based treatment for HD with or without compensatory cognitive training. Hoarding symptoms were assessed following the final treatment session to index treatment response. Results: IU was positively and significantly associated with greater urges to acquire and greater difficulties discarding possessions, beyond shared variance accounted for by anxiety and depression. IU was not significantly related to clutter symptom severity. Higher pre-treatment IU predicted increased odds of treatment non-response. Conclusions: Elevated IU is associated with specific hoarding symptom clusters and may be an important target for HD treatment. © 2018

Integrity signals

Registry

Crossref · 10.1016/j.jocrd.2018.11.005

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

5 of 15 cited sources checked · 4 supported · 0 flagged · accuracy not yet measured

  • Study design and conductcitation

    All participants met DSM-5 criteria for hoarding disorder, established by clinical interview and scores on the UHSS and SI-R.

    “All participants were required to meet DSM-5 criteria for HD, determined using a clinical interview in conjunction with scores on the UCLA Hoarding Severity Scale (UHSS; Saxena, Ayers, Dozier, & Maidment, 2015), a 10-items clinician-administered assessment, and on the Savings Inventory- Revised (SI-R; Frost et al., 2004), a 23-item self-report measure.”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites Saxena, Ayers, Dozier, & Maidment, 2015 source
    • cites Frost et al., 2004 source
  • Findingown data

    HADS anxiety and depression scores predicted significant variance in SI-R difficulty discarding and acquiring scores.

    “The HADS Anxiety and Depression subscales were entered in the first step of all regression analyses and predicted significant variance in the SI-R Difficulty Discarding subscale (F (2, 54) = 8.95, p = 0.0004), and the SI-R Acquiring subscale (F (2, 54) = 9.45, p = 0.0003).”
    Quote in the paperNot a substantial claim
  • Findingown data

    The proportion of treatment responders did not differ significantly between participants who received exposure therapy plus compensatory cognitive training and those who received exposure therapy alone.

    “A similar percentage of participants who received CCT + exposure therapy and who received exposure therapy only were classified as treatment responders (32% vs. 30%; X2 (1) = 0.03, p = 0.873); thus, treatment type was not included in the subsequent analysis.”
    Quote in the paperSubstantial claim
  • Findingown data

    In treatment-seeking adults with hoarding disorder, intolerance of uncertainty was positively associated with urges to acquire and difficulty discarding, after controlling for anxiety and depression.

    “IU was positively and significantly associated with greater urges to acquire and greater difficulties discarding possessions, beyond shared variance accounted for by anxiety and depression.”
    • Also stated in: § Hierarchical analyses · plain
      “The IUS-12 accounted for significant additional variance on the SI-R Difficulty Discarding subscale (∆R2 = 0.0852, p = 0.012) and the SI-R Acquiring subscale (∆R2 = 0.1734, p < 0.001).”
    • Also stated in: § Discussion · plain
      “The results supported our primary hypothesis that elevated IU is associated with increased hoarding severity, and that this relationship is over and above the relationship between IU and symptoms of anxiety and depression.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: Anxiety and depression severity are the only relevant confounders of the association between intolerance of uncertainty and hoarding symptoms.
  • Findingown data

    In treatment-seeking adults with hoarding disorder, intolerance of uncertainty was not significantly associated with clutter severity.

    “IU was not significantly related to clutter symptom severity.”
    • Also stated in: § Descriptive statistics · plain
      “Because the CIR and the SI-R Clutter subscale were not significantly correlated with the IUS-12 (both ps > 0.05), they were not included in subsequent analyses.”
    • Also stated in: § Discussion · plain
      “IU was only related to the acquiring and difficulty discarding symptoms of HD and not the clutter symptom.”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim. 14
  • May combine two claims. 10
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Premisecitation

    The CIR has been validated in older hoarding disorder samples and shows excellent patient-clinician inter-rater reliability.

    “The CIR has been validated for use in older HD samples (Dozier & Ayers, 2015), and has excellent inter-rater reliability between patient and clinician (Dozier & Ayers, 2015; Frost et al., 2004).”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites Dozier & Ayers, 2015 source

      The Discussion says the CIR is valid and reliable for assessing clutter in older adults with hoarding disorder. The Results report a significant patient–clinician rating correlation (r = 0.54), but do not characterize that agreement as excellent; the high reliability figure (α = 0.86) concerns internal consistency, not patient–clinician agreement. (LLM, conf=0.88)

      Experimental — accuracy not yet measured
    • cites Frost et al., 2004 source
  • May combine two claims.

    Interpretationcitation

    The null association between intolerance of uncertainty and clutter is consistent with prior research linking acquiring and difficulty discarding to experiential avoidance, with clutter likely a consequence of those two symptoms.

    “This finding is consistent with previous research indicating that acquiring and difficulty discarding are related to experiential avoidance (avoidance of distressing internal experiences), whereas clutter is not related, and is likely a consequence of the other two sub-factors (Ayers, Castriotta, Dozier, Espejo, & Porter, 2014).”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites Ayers, Castriotta, Dozier, Espejo, & Porter, 2014 source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductown data

    A power analysis indicated that the sample of 57 had 80% power to detect a medium-to-large effect for the baseline regressions and a large effect for the logistic regression.

    “A power analysis conducted using G*Power (Faul, Erdfelder, Buchner, & Lang, 2009) indicated that using an alpha of 0.05 the study sample size of 57 had 0.80 power to detect a medium to large effect (f2 = 0.15) for the baseline regression analyses and to detect a large effect (odds ratio = 2.43) for the logistic regression analysis.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites Faul, Erdfelder, Buchner, & Lang, 2009 source
  • May combine two claims.

    Interpretationcitation

    The treatment-response findings are consistent with prior research showing that baseline intolerance of uncertainty predicts residual anxiety and worry after treatment and that reductions in intolerance of uncertainty predict overall improvement.

    “These findings are consistent with previous research that has found that baseline IU predicts residual symptoms of anxiety and worry following treatment for anxiety disorders (Keefer et al., 2017) and that reductions in IU throughout treatment predict level of overall improvement (e.g. Boswell et al., 2013; Talkovsky & Norton, 2016).”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites Keefer et al., 2017 source
    • cites Boswell et al., 2013 source
    • cites Talkovsky & Norton, 2016 source
  • Classified as probably not a substantial claim.

    Findingown data

    The analyzed sample comprised 57 treatment-seeking individuals with hoarding disorder.

    “Fifty-seven individuals seeking treatment for HD completed baseline measures of hoarding symptoms, IU, anxiety and depression.”
    • Also stated in: § Participants · plain
      “Of the 60 individuals included in the parent study, baseline data on intolerance of uncertainty was available for only 57 people. The baseline and post-treatment scores for these 57 individuals was utilized for the current investigation.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The sample was predominantly female, Caucasian, and unmarried.

    “Participants were mostly female (74%), Caucasian (79%), and unmarried (75%).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The mean age of participants was 58.28 years (SD = 9.65, range 29-77).

    “The average age of participants was 58.28 (SD = 9.65, range: 29–77).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In the baseline sample, SI-R total, difficulty discarding, and acquiring scores were significantly correlated with IUS-12 scores, as were HADS anxiety and depression scores.

    “The SI-R Total and Difficulty Discarding and Acquiring subscales were significantly correlated with the IUS-12, as was the HADS Anxiety and Depression subscales (all ps < 0.05).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Internal consistency of the IUS was adequate in the current sample.

    “Internal consistency of the IUS in the current sample was adequate (α = 0.92).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductnone given

    Final hoarding disorder diagnoses were made by the principal investigator after reviewing assessment results in weekly supervision with study assessors.

    “Final HD diagnosis was determined by the PI of the parent study after review of assessment results during weekly supervision with study assessors.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    The study provides evidence that intolerance of uncertainty functions similarly in hoarding disorder and anxiety disorders and may be a common vulnerability factor across disorders.

    “This initial study of the impact of IU on HD treatment outcome provides further evidence that IU functions similarly in HD as in anxiety disorders, and that IU may represent a common vulnerability factor across disorders.”
    Quote in the paperSubstantial claim
    • Rests on an assumption: Intolerance of uncertainty plays a causal or maintaining role in hoarding symptoms, such that targeting it would reduce hoarding.
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Internal consistency of the CIR was adequate in the current sample.

    “Internal consistency of the CIR in the current sample was adequate (α = 0.78).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductown data

    The study received Institutional Review Board approval and all participants gave written informed consent.

    “The study protocol was approved by the Institutional Review Board of (institution name removed to keep authorship confidential) and all participants provided written informed consent.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Internal consistency of the SI-R total and its subscales was adequate in the current sample.

    “Internal consistency of the SI-R in the current sample was adequate for the total score (α = 0.90) and all subscales (difficulty discarding: α = 0.82; acquiring: α = 0.83; clutter: α = 0.93).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The short form of the IUS correlates highly with the original 27-item IUS.

    “The shortened version of the IUS has been found to be highly correlated with the original 27-item IUS scale (r = 0.96; Carleton et al., 2007).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites Carleton et al., 2007 source
  • May combine two claims.

    Interpretationcitation

    A prior study found similar results in a subclinical, non-treatment-seeking sample, suggesting the relationship between hoarding disorder and intolerance of uncertainty spans severity levels.

    “However, a previous study (Oglesby et al., 2012) found similar results in a subclinical, non-treatment seeking sample, suggesting that the relationship between HD and IU is present across a spectrum of severity levels.”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites Oglesby et al., 2012

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Classified as probably not a substantial claim.

    Study design and conductcitation

    Hoarding severity was measured with two validated self-report instruments, the SI-R and the CIR.

    “Hoarding severity was assessed using two well-validated self-report scales, the Saving Inventory-Revised (SI-R; Frost et al., 2004) and the Clutter Image Rating (CIR; Frost, Steketee, Tolin, & Renaud, 2008).”
    Quote in the paperSubstantial claim0 of 2 sources checked
    • cites Frost et al., 2004 source
    • cites Frost, Steketee, Tolin, & Renaud, 2008 source
  • May combine two claims.

    Interpretationown data

    The sample was largely Caucasian and female, so the results may not generalize to other cultural groups or to males.

    “Our sample was largely Caucasian and female, and thus the results may not generalize to other cultural groups or males.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    Internal consistency of the HADS anxiety and depression subscales was adequate in the current sample.

    “Internal consistency of both subscales was adequate in the current sample (Anxiety: α = 0.81; Depression: α = 0.86).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Interpretationreasoning

    The reliance on self-report measures of hoarding severity and intolerance of uncertainty may have introduced bias relative to clinician-administered measures.

    “This study relied on self-report measures of hoarding symptom severity and IU, which may be more subject to bias than clinician administered measures.”
    Quote in the paperNot a substantial claim
20 of 20
  • The paper relies on this without support.

    Intolerance of uncertainty plays a causal or maintaining role in hoarding symptoms, such that targeting it would reduce hoarding.

    “IU may be an important target for HD treatment.”
  • The paper relies on this without support.

    Anxiety and depression severity are the only relevant confounders of the association between intolerance of uncertainty and hoarding symptoms.

    “IU was positively and significantly associated with greater urges to acquire and greater difficulties discarding possessions, beyond shared variance accounted for by anxiety and depression.”
2 of 2

Statistics recomputed

Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.

  • ConsistentF(2, 54) = 8.95reported p = .0004 · recomputed p < .001

    “F (2, 54) = 8.95, p = .0004”

  • ConsistentF(2, 54) = 9.45reported p = .0003 · recomputed p < .001

    “F (2, 54) = 9.45, p = .0003”

  • Consistentχ²(1) = 0.03reported p = .873 · recomputed p = .862

    “X2 (1) = 0.03, p = .873”

  • Consistentz = -2.35reported p = .019 · recomputed p = .019

    “z = −2.35, p = .019”

4 of 4

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

  • The prior hoarding-and-IU study is assigned two publication years

    Minor

    The introduction identifies Oglesby et al. (2013) as the sole prior study directly investigating this relationship. The discussion refers to the previous study of that relationship as Oglesby et al. (2012).

1 of 1

Cites

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1 of the 38 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Castriotta, N., Dozier, M. E., Taylor, C. T., Mayes, T., & Ayers, C. R.
Affiliations
  • VA San Diego Healthcare System (US)
  • San Diego State University (US)
  • University of California San Diego (US)
Corresponding author
Castriotta, Natalie
Venue
Journal of Obsessive-Compulsive and Related Disorders
Publisher
Elsevier BV
Published
2019-04
Volume
21
Pages
97-101
ISSN
2211-3649 (ISSN-L)
OpenAlex
W2903449293
Cited by
24
References
38
Citations by year
2026: 1 · 2025: 3 · 2024: 4 · 2023: 6 · 2022: 2 · 2021: 4 · 2020: 2 · 2019: 2
FWCI
2.35
Type
journal article
Language
en
Open access
Locations
  • Journal of Obsessive-Compulsive and Related Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
Veterans Health Administration Clinical Science R & D Program (CSRD-068-10S and CLNA-005-14S)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Perfectionism, Procrastination, Anxiety Studies
Keywords
intolerance of uncertainty, hoarding disorder, transdiagnostic risk factors, clutter, exposure therapy, treatment response prediction, compensatory cognitive training, anxiety, depression

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Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-09-28.

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Statistics and arithmetic are recomputed, not judged.

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