Oral Function After Oncological Intervention in the Oral Cavity: A Retrospective Study
Abstract
Purpose To assess self-perceived oral function of patients with oral cavity cancer at different stages of treatment, ie, before oncologic intervention, 5 weeks after intervention, and 5 years after intervention.Patients and methods A cohort of 158 patients with malignancy in the oral cavity treated by surgery in 1999 or 2000 was included. From this cohort we interviewed 69 patients by telephone in 2005 and collected data on dental status, disorders of chewing and swallowing, xerostomia, preference of food consistency, tube nutrition, weight loss, and speech for different stages of treatment.Results For patients treated in the maxilla region we observed a significant (P < .05) recovery of perceived chewing ability after 5 years to the level experienced before oncologic intervention. Patients treated in the mandible region reported a deteriorated dental state, chewing ability, lip competence, and xerostomia after 5 years. Patients treated in the tongue and mouth-floor region experienced deterioration for dental state, chewing ability, and xerostomia after 5 years compared with the level before the oncologic intervention.Conclusions Our telephone interview on oral function provided supplementary information on how patients experienced their problems with oral function during various phases of oncologic treatment. A retrospective interview may thus help to add information to incomplete retrospective data.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Following maxillary ablation, there is often a functional or non-functional compensation of upper to lower lip interaction and lip competence, which may severely limit any dental rehabilitation protocol; additionally, radiation, immunotherapy and/or chemotherapy may present additional challenges to reconstruction.
“Following maxillary ablation, there is often a functional or non-functional compensation of upper to lower lip interaction and lip competence, which may severely limit any dental rehabilitation protocol; additionally, radiation, immunotherapy and/or chemotherapy may present additional challenges to reconstruction [12].”
Cites
A structural approach to selection bias
Hernán, M. A., Hernández-Díaz, S., & Robins, J. M. (2004) · Epidemiology · doi:10.1097/01.ede.0000135174.63482.43 · Cited by 2,844 · see citing works
Recall bias in epidemiologic studies
Coughlin, S. S. (1990) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(90)90060-3 · Cited by 1,381 · see citing works
The seven sins of memory: Insights from psychology and cognitive neuroscience.
Schacter, D. L. (1999) · American Psychologist · doi:10.1037/0003-066x.54.3.182 · Cited by 1,133 · see citing works
Schwartz, C. E., & Sprangers, M. A. G. (1999) · Social Science & Medicine · doi:10.1016/s0277-9536(99)00047-7 · Cited by 829 · see citing works
Biting and Chewing in Overdentures, Full Dentures, and Natural Dentitions
Fontijn-Tekamp, F. A., Slagter, A. P., van der Bilt, A., Hof, M. A. V. '., Witter, D. J., Kalk, W., & Jansen, J. A. (2000) · Journal of Dental Research · doi:10.1177/00220345000790071501 · Cited by 826 · see citing works
Capturing the patient's view of change as a clinical outcome measure.
Fischer, D., Stewart, A., Bloch, D., Lorig, K., Laurent, D. D., & Holman, H. (1999) · Journal of the American Medical Association (JAMA) · doi:10.1001/jama.282.12.1157 · Cited by 501 · see citing works
Schacter, D. L., Chiao, J., & Mitchell, J. P. (2003) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1279.012 · Cited by 455 · see citing works
An optimization model for mastication and swallowing in mammals
Prinz, J., & Lucas, P. W. (1997) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1997.0238 · Cited by 355 · see citing works
Urken, M. L., Buchbinder, D., Weinberg, H., et al. (1991) · The Laryngoscope · doi:10.1288/00005537-199109000-00004 · Cited by 346 · see citing works
Chambers, M. S., Garden, A. S., Kies, M. S., & Martin, J. W. (2004) · Head & Neck · doi:10.1002/hed.20045 · Cited by 277 · see citing works
Pauloski, B. R., Logemann, J. A., RADEMAKER, A. W., McConnel, F. M. S., Heiser, M. A., Cardinale, S., Shedd, D. P., Lewin, J. S., Baker, S. R., Graner, D. E., et al. (1993) · Journal of Speech Language and Hearing Research · doi:10.1044/jshr.3602.267 · Cited by 171 · see citing works
de Graeff, A., de Leeuw, J. R. J., Ros, W. J. G., Hordijk, G. J., Blijham, G. H., & Winnubst, J. A. M. (1999) · Oral Oncology · doi:10.1016/s1368-8375(98)00049-9 · Cited by 164 · see citing works
Scott, B., Butterworth, C., Lowe, D., & Rogers, S. N. (2007) · Oral Oncology · doi:10.1016/j.oraloncology.2007.06.015 · Cited by 162 · see citing works
Effects of xerostomia on perception and performance of swallow function
Logemann, J. A., Smith, C. H., Pauloski, B. R., RADEMAKER, A. W., Lazarus, C. L., Colangelo, L. A., Mittal, B. B., MacCracken, E., Gaziano, J. E., Stachowiak, L., et al. (2001) · Head & Neck · doi:10.1002/hed.1037 · Cited by 150 · see citing works
Physical activity and quality of life in head and neck cancer survivors
Rogers, L. Q., Courneya, K. S., Robbins, K. T., Malone, J. P., Seiz, A., Koch, L., Rao, K., & Nagarkar, M. (2006) · Supportive Care in Cancer · doi:10.1007/s00520-006-0044-7 · Cited by 146 · see citing works
Speech and Swallow Function After Tonsil/Base of Tongue Resection With Primary Closure
Logemann, J. A., Pauloski, B. R., RADEMAKER, A. W., et al. (1993) · Journal of Speech Language and Hearing Research · doi:10.1044/jshr.3605.918 · Cited by 145 · see citing works
Surgical variables affecting swallowing in patients treated for oral/oropharyngeal cancer
Pauloski, B. R., RADEMAKER, A. W., Logemann, J. A., et al. (2004) · Head & Neck · doi:10.1002/hed.20013 · Cited by 134 · see citing works
Rabinovitch, R. A., Grant, B. L., Berkey, B. A., Raben, D., Ang, K. K., Fu, K. K., Cooper, J. S., & for the Radiation Therapy Oncology Group (2005) · Head & Neck · doi:10.1002/hed.20335 · Cited by 119 · see citing works
Nicoletti, G. J., Soutar, D. S., Jackson, M. S., et al. (2004) · Plastic & Reconstructive Surgery · doi:10.1097/01.prs.0000131872.90767.50 · Cited by 113 · see citing works
Llewellyn, C. D., McGurk, M., & Weinman, J. A. (2005) · Oral Oncology · doi:10.1016/j.oraloncology.2004.12.006 · Cited by 100 · see citing works
Mastication and swallowing in patients with postirradiation xerostomia
Hamlet, S. L., Faull, J., Klein, B., Aref, A. M., Fontanesi, J., Stachler, R. J., Shamsa, F. H., Jones, L., & Simpson, M. L. (1997) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(96)00604-9 · Cited by 100 · see citing works
Pauloski, B. R., RADEMAKER, A. W., Logemann, J. A., Newman, L. A., MacCracken, E., Gaziano, J. E., & Stachowiak, L. (2006) · Head & Neck · doi:10.1002/hed.20459 · Cited by 88 · see citing works
Gleich, L. L., Biddinger, P. W., Duperier, F. D., & Gluckman, J. L. (1997) · Head & Neck · doi:10.1002/(sici)1097-0347(199707)19:4 · Cited by 85 · see citing works
Borggreven, P. A., Leeuw, I. M. V., Langendijk, J. A., Doornaert, P., Koster, M. N., de Bree, R., & Leemans, C. R. (2005) · Head & Neck · doi:10.1002/hed.20236 · Cited by 72 · see citing works
Namaki, S., Matsumoto, M., Ohba, H., et al. (2004) · Journal of Oral Science · doi:10.2334/josnusd.46.113 · Cited by 69 · see citing works
Functional Analysis of Treatment of Oral Cavity Cancer
Teichgraeber, J. F., Bowman, J. B., & Goepfert, H. (1986) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1986.03780090055010 · Cited by 64 · see citing works
Clinical function after primary surgery for oral and oropharyngealcancer: an 11-item examination
Rogers, S. N., Lowe, D., Patel, M., et al. (2002) · British Journal of Oral and Maxillofacial Surgery · doi:10.1054/bjom.2001.0701 · Cited by 61 · see citing works
Effect of bolus size on chewing, swallowing, oral soft tissue and tongue movement
Blissett, A., Prinz, J. F., Wülfert, F., et al. (2007) · Journal of Oral Rehabilitation · doi:10.1111/j.1365-2842.2007.01756.x · Cited by 60 · see citing works
Effects of psychosocial intervention on quality of life in patients with head and neck cancer
Petruson, K. M., Silander, E. M., & Hammerlid, E. B. (2003) · Head & Neck · doi:10.1002/hed.10243 · Cited by 52 · see citing works
Oral cavity reconstruction: An objective assessment of function
Haribhakti, V. V., Kavarana, N. M., & Tibrewala, A. N. (1993) · Head & Neck · doi:10.1002/hed.2880150207 · Cited by 51 · see citing works
Masticatory function in hemimandibulectomy patients
Marunick, M. T., Mathes, B. E., & KLEIN, B. B. (1992) · Journal of Oral Rehabilitation · doi:10.1111/j.1365-2842.1992.tb01104.x · Cited by 47 · see citing works
Pace‐Balzan, A., Cawood, J. I., Howell, R. A., et al. (2005) · International Journal of Oral and Maxillofacial Surgery · doi:10.1016/j.ijom.2005.07.004 · Cited by 47 · see citing works
A procedure for reducing errors in reports of life events
Sobell, L. C., Toneatto, T., Sobell, M. B., Schuller, R., & Maxwell, M. (1990) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(90)90050-e · Cited by 34 · see citing works
Comparison of food mixing ability among mandibulectomy patients
Kadota, C., Sumita, Y. I., WANG, Y., et al. (2008) · Journal of Oral Rehabilitation · doi:10.1111/j.1365-2842.2007.01814.x · Cited by 33 · see citing works
Comparative evaluation of function after surgery for cancer of the alveolobuccal complex
Patel, S. G., Deshmukh, S. P., Savant, D., et al. (1996) · Journal of Oral and Maxillofacial Surgery · doi:10.1016/s0278-2391(96)90685-0 · Cited by 16 · see citing works
Restrictions of food intake in patients with oral cancer
Toporcov, T. N., & Antunes, J. L. F. (2006) · Oral Oncology · doi:10.1016/j.oraloncology.2005.12.013 · Cited by 16 · see citing works
Unlined repairs of defects following oral cancer ablation
Gabriel, A. (1976) · British Journal of Plastic Surgery · doi:10.1016/0007-1226(76)90044-8 · Cited by 3 · see citing works
Frost (2004) · doi:10.1043/0003-3219(2004)074
Flagged first, then by citations
Cited by
Sorted by citations
Gellrich, N.-C., Korn, P., Jehn, P., Lentge, F., Neuhaus, M.-T., & Rahlf, B. (2025) · Head & Face Medicine · doi:10.1186/s13005-025-00549-y · Cited by 2 · see citing works
“…there is often a functional or non-functional compensation of upper to lower lip interaction and lip competence, which may severely limit any dental rehabilitation protocol; additionally, radiation, immunotherapy and/or chemotherapy may present additional challenges to reconstruction [12].”
- Authors
- Speksnijder, C. M., van der Glas, H. W., van der Bilt, A., van Es, R. J. J., van der Rijt, E., & Koole, R.
- Affiliations
- University Medical Center Utrecht (NL)
- Corresponding author
- Speksnijder, Caroline M.
- Venue
- Journal of Oral and Maxillofacial Surgery
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 68
- Issue
- 6
- Pages
- 1231-1237
- ISSN
- 0278-2391 (ISSN-L)
- OpenAlex
- W2052372567
- Cited by
- 50
- References
- 38
- Citations by year
- 2025: 4 · 2024: 1 · 2023: 3 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 2 · 2018: 8 · 2017: 1 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 6 · 2012: 3
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Oral and Maxillofacial Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Oral health in cancer treatment
- Health Sciences › Medicine › Otorhinolaryngology › Head and Neck Cancer Studies
- Health Sciences › Health Professions › Speech and Hearing › Dysphagia Assessment and Management
- Keywords
- oral function, oral cancer, chewing ability, dysphagia, xerostomia, dental status, tube feeding, weight loss, speech, maxillary surgery, mandibular surgery, tongue cancer, long-term outcomes
- MeSH terms
- Aged, Deglutition, Facial Pain, Female, Follow-Up Studies, Humans, Interviews as Topic, Jaw Neoplasms, Lip, Male, Mastication, Middle Aged, Mouth Neoplasms, Neoplasm Staging, Nutritional Status, Retrospective Studies, Speech, Telephone, Xerostomia, Weight Loss, Chi-Square Distribution, Tooth Loss, Statistics, Nonparametric, Recovery of Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
