Optimizing treatment of acne with photodynamic therapy (PDT) to achieve long-term remission and reduce side effects. A prospective randomized controlled trial

Acne vulgaris

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Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light

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Macrophage responsiveness to light therapy

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Photodynamic Therapy: A Clinical Consensus Guide

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Treatment of Acne Vulgaris

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Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate

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Photodynamic therapy of acne vulgaris using methyl aminolaevulinate: a blinded, randomized, controlled trial

Wiegell, S. R., & Wulf, H. C. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2005.07107.x · Cited by 197 · see citing works

Photodynamic therapy of actinic keratosis at varying fluence rates: assessment of photobleaching, pain and primary clinical outcome

Ericson, M. B., Sandberg, C., Stenquist, B., Gudmundson, F., Karlsson, M., Ros, A.-M., Rosen, A., Larkö, O., Wennberg, A.-M., & Rosdahl, I. K. (2004) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2004.06211.x · Cited by 159 · see citing works

Propionibacterium acnes and antimicrobial resistance in acne

Dessinioti, C., & Katsambas, A. (2016) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2016.10.008 · Cited by 145 · see citing works

Topical methyl aminolaevulinate photodynamic therapy for treatment of facial acne vulgaris: results of a randomized, controlled study

Hörfelt, C., Funk, J., Frohm‐Nilsson, M., Edström, D. W., & Wennberg, A.-M. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07340.x · Cited by 132 · see citing works

Terapia fotodinâmica: revisão da literatura e documentação iconográfica

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Photodynamic therapy for acne vulgaris: A critical review from basics to clinical practice

Sakamoto, F. H., Torezan, L. A. R., & Anderson, R. R. (2010) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2009.09.057 · Cited by 127 · see citing works

The psychosocial impact of acne, vitiligo, and psoriasis: a review

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The Role of Photodynamic Therapy in Acne: An Evidence-Based Review

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Singlet Oxygen (1Δg) Generation from Coproporphyrin inPropionibacterium acneson Irradiation

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Long-pulsed dye laser-mediated photodynamic therapy combined with topical therapy for mild to severe comedonal, inflammatory, or cystic acne.

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Outcome measures in acne vulgaris: systematic review

Barratt, H., Hamilton, F. L., Car, J., Lyons, C., Layton, A., & Majeed, A. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08819.x · Cited by 69 · see citing works

Photodynamic therapy for the treatment of different severity of acne: A systematic review

Keyal, U., Bhatta, A. K., & Wang, X. L. (2016) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2016.04.005 · Cited by 60 · see citing works

Microscopic localisation of protoporphyrin IX in normal mouse skin after topical application of 5-aminolevulinic acid or methyl 5-aminolevulinate

de Bruijn, H. S., Meijers, C., den Heuvel, A. V. D. P., Sterenborg, H. J. C. M., & Robinson, D. J. (2008) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2008.05.005 · Cited by 58 · see citing works

Light therapies for acne

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Fluorescence contrast and threshold limit: implications for photodynamic diagnosis of basal cell carcinoma

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Clinical safety and efficacy studies of a novel formulation combining 1.2% clindamycin phosphate and 0.025% tretinoin for the treatment of acne vulgaris.

Schlessinger, J., Menter, A., Gold, M. H., Leonardi, C. T., Eichenfield, L. F., Plott, R. T., Leyden, J. J., & Wortzman, M. S. (2007) · PubMed · Cited by 48 · see citing works

Photodynamic therapy with methyl aminolaevulinate 80 mg g−1for severe facial acne vulgaris: a randomized vehicle-controlled study

Pariser, D. M., Eichenfield, L. F., Bukhalo, M., Waterman, G., Jarratt, M., & the PDT Study Group (2015) · British Journal of Dermatology · doi:10.1111/bjd.14345 · Cited by 40 · see citing works

Single Low-dose Red Light is as Efficacious as Methyl-aminolevulinate-photodynamic Therapy for Treatment of Acne: Clinical Assessment and Fluorescence Monitoring

Hörfelt, C., Stenquist, B., Halldin, C. B., Ericson, M. B., & Wennberg, A.-M. (2009) · Acta Dermato Venereologica · doi:10.2340/00015555-0667 · Cited by 34 · see citing works

Photodynamic therapy with methylaminolevulinate 80 mg/g without occlusion improves acne vulgaris.

Bissonnette, R., Maari, C., Nigen, S., Provost, N., & Bolduc, C. (2010) · PubMed · Cited by 33 · see citing works

Efficacy of red light alone and methyl-aminolaevulinate-photodynamic therapy for the treatment of mild and moderate facial acne

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Short‐contact, low‐dose methyl aminolaevulinate photodynamic therapy for acne vulgaris

Dessinioti, C., Masouri, S., Drakaki, E., Katsambas, A., & Antoniou, C. (2016) · British Journal of Dermatology · doi:10.1111/bjd.14460 · Cited by 14 · see citing works

Isotretinoin in retrospect

Karadağ, A. S., Parish, L. C., & Lambert, W. C. (2016) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2016.12.002 · Cited by 13 · see citing works

Reactive Oxygen Species (ROS)-Mediated Antibacterial Oxidative Therapies: Available Methods to Generate ROS and a Novel Option Proposal

Alfei, S., Schito, G. C., Schito, A. M., & Zuccari, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25137182 · Cited by 316 · see citing works

Effect of skin color on optical properties and the implications for medical optical technologies: a review

Setchfield, K., Gorman, A., Simpson, A. H. R. W., Somekh, M. G., & Wright, A. J. (2024) · Journal of Biomedical Optics · doi:10.1117/1.jbo.29.1.010901 · Cited by 72 · see citing works

Combinations of Photodynamic Therapy with Other Minimally Invasive Therapeutic Technologies against Cancer and Microbial Infections

Songca, S. P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241310875 · Cited by 38 · see citing works

Acne Vulgaris—Novel Treatment Options and Factors Affecting Therapy Adherence: A Narrative Review

Tobiasz, A., Nowicka, D., & Szepietowski, J. C. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11247535 · Cited by 36 · see citing works

The photosensitizer-based therapies enhance the repairing of skin wounds

Ning, X., He, G., Zeng, W., & Xia, Y. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.915548 · Cited by 29 · see citing works

Photodynamic therapy: Clinical applications in dermatology

Wang, J. Y., Zeitouni, N. C., Austin, E., Jagdeo, J. R., Lim, H. W., & Ozog, D. (2025) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2024.12.050 · Cited by 27 · see citing works

Nanoparticle-Based Therapeutic Strategies for Enhanced Pancreatic Ductal Adenocarcinoma Immunotherapy

Hou, W., Yang, B., & Zhu, H. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14102033 · Cited by 26 · see citing works

Light and laser-based therapy in treatment of acne vulgaris: A clinical review

Ishii, L., Deoghare, S., & Boen, M. (2025) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2025.06.046 · Cited by 17 · see citing works

Photodynamic therapy alone or in combination to counteract bacterial infections

Clément, S., & Winum, J. (2024) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2024.2327308 · Cited by 17 · see citing works

Review of the European Society for Photodynamic Therapy (Euro-PDT) Annual Congress 2022

Morton, C. A., Szeimies, R., & Braathen, L. R. (2023) · European Journal of Dermatology · doi:10.1684/ejd.2023.4562 · Cited by 14 · see citing works

Photodynamic Therapy in Acne Vulgaris: A Systematic Review

Qureshi, S., Rehan, Z., Ao, A., & Mukovozov, I. (2024) · Journal of Cutaneous Medicine and Surgery · doi:10.1177/12034754241291031 · Cited by 13 · see citing works

Photodynamic Therapy: Advancement in Therapeutic and Cosmetic Application for Targeted Treatment: A Review

Nayak, P., Sahani, S., Samal, H. B., Jena, G. K., Kar, R. K., & Mohapatra, S. (2024) · Biomedical Materials & Devices · doi:10.1007/s44174-024-00248-3 · Cited by 8 · see citing works

5-Aminolevulinic Acid Photodynamic Therapy Modulates Lipid Production by Akt/JunD-mediated NR4A1 Activation in the Treatment of Acne Vulgaris.

Wu, Y., Liu, X.-J., Zhang, L.-L., Wang, P.-R., Zhang, H.-Y., Yan, J., Yan, Y., Liu, P., Zhao, J.-J., Zeng, Q.-Y., et al. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.01.018 · Cited by 7 · see citing works

Effect of various types of photodynamic therapy on inflammatory and non-inflammatory lesions in patients with acne: A network meta-analysis of randomized controlled trials

Long, X.-X., Xie, A.-D., Yang, P., Xie, J., Chen, X.-L., Huang, Y.-D., Zhang, L., & Peng, X. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103365 · Cited by 6 · see citing works

Different Effects of Phototherapy for Rat Glioma during Sleep and Wakefulness

Shirokov, A. A., Андреевна, Б. И., Fedosov, I. V., Ilyukov, E., Terskov, A. V., Myagkov, D., Tuktarov, D., Tsoy, M. O., Adushkina, V., Zlatogosrkaya, D., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12020262 · Cited by 4 · see citing works

Advances and perspectives in use of semisolid formulations for photodynamic methods

Ziental, D., Czarczyńska-Goślińska, B., Wysocki, M., Ptaszek, M., & Sobotta, Ł. (2024) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2024.114485 · Cited by 4 · see citing works

Hypericin-mediated photodynamic therapy promotes apoptosis and inhibits fibrosis by inducing HMOX1-mediated ferroptosis in hypertrophic scar fibroblasts

Li, X., Chen, Z., Liu, M., An, J., Shang, J., Zhu, G., Wen, H., & Guo, G. (2025) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2025.113303 · Cited by 3 · see citing works

Long-Term Improvement of Different Types of Acne Vulgaris Using a Mild Photodynamic Therapy Protocol with BF-200 ALA Gel: A Series of Cases

Serra-Guillén, C., Llombart, B., & Sanmartín, O. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13092658 · Cited by 3 · see citing works

Phototherapy for Acne Vulgaris: Strategies and Clinical Applications in Sebum Modulation, Inflammation Control, and Scar Management

Ren, X., Ge, L., & Song, Z. (2026) · Photobiomodulation Photomedicine and Laser Surgery · doi:10.1177/25785478261438102 · Cited by 2 · see citing works

Cyclodextrins as nanocarriers of hydrophobic silicon phthalocyanine dichloride for the enhancement of photodynamic therapy effect

Georgiopoulou, E., Kavetsou, E., Alexandratou, E., Detsi, A., & Politopoulos, K. (2024) · Journal of Biomaterials Applications · doi:10.1177/08853282241306858 · Cited by 2 · see citing works

Lasers and Lights for Acne

Steuer, A. B., Rajanala, S., Saedi, N., & Dover, J. S. (2025) · Advances in Cosmetic Surgery · doi:10.1016/j.yacs.2024.12.001 · Cited by 1 · see citing works

Effect of Thirteen Kinds of Photodynamic Therapeutic Schedule on Inflammatory and Non-Inflammatory Lesions in Acne Patients—A Network Meta-Analysis of Randomized Controlled TrialsPreprint

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Acne Demystified: A Roadmap to Clear and Healthy Skin for Your Patients

Sparling, K., & O’Haver, J. (2023) · Clinical Pediatrics · doi:10.1177/00099228231210710

Isotretinoin in retrospect

Karadağ, A. S., Parish, L. C., & Lambert, W. C. (2016) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2016.12.002 · Cited by 13 · see citing works

The activities of phthalocyanins of platinum group metals

Berezin, B. D. (1968) · Journal of Catalysis · doi:10.1016/0021-9517(68)90189-9

Photodynamic therapy with methylaminolevulinate 80 mg/g without occlusion improves acne vulgaris.

Bissonnette, R., Maari, C., Nigen, S., Provost, N., & Bolduc, C. (2010) · PubMed · Cited by 33 · see citing works

Photodynamic therapy with methyl aminolaevulinate 80 mg g−1for severe facial acne vulgaris: a randomized vehicle-controlled study

Pariser, D. M., Eichenfield, L. F., Bukhalo, M., Waterman, G., Jarratt, M., & the PDT Study Group (2015) · British Journal of Dermatology · doi:10.1111/bjd.14345 · Cited by 40 · see citing works

Photodynamic therapy of acne vulgaris using methyl aminolaevulinate: a blinded, randomized, controlled trial

Wiegell, S. R., & Wulf, H. C. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2005.07107.x · Cited by 197 · see citing works