The impact of psychiatric illness on suicide: Differences by diagnosis of disorders and by sex and age of subjects
Abstract
People with a psychiatric illness are at high risk for suicide; however, variation of the risk by patients' sex and age and by specific diagnosis needs to be explored in a more detail. This large population study systematically assesses suicide incidence rate ratio (IRR) and population attributable risk (PAR) associated with various psychiatric disorders by comparing 21,169 suicides in Denmark over a 17-year period with sex-age-time-matched population controls. The study shows that suicide risk is significantly increased for persons with a hospitalized psychiatric disorder and the associated risk varies significantly by diagnosis and by sex and age of subjects. Further adjustment for personal socioeconomic differences eliminates the IRRs associated with various disorders only to a limited extend. Recurrent depression and borderline personality disorder increase suicide risk the strongest while dementia increases the risk the least for both males and females. The influence of various disorders generally weakens with increasing age; however, there are important exceptions. Schizophrenia affects people aged ≤35 years the strongest in terms of both IRR and PAR. Recurrent depression increases suicide risk particularly strong in all age groups and the associated PAR increases steadily with age. Borderline personality disorder has a strong effect in young people, especially those ≤35 years. Alcohol use disorder accounts the highest PAR of suicides in males of 36-60 years old. For the elderly above 60 years old, reaction to stress and adjustment disorder increases the risk for suicide the most in both sexes. These findings suggest that approaches to psychiatric suicide prevention should be varied according to diagnosis and sex and age of subjects.
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Adjustment disorder, if undetected and untreated, may lead to more severe mental disorders or an elevated risk of suicide.
“if it goes undetected and untreated it may lead to more severe mental disorders or an elevated risk of suicide [67, 68]”
From Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies (2020) · cites this paper as [67]
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- Authors
- Qin, P.
- Affiliations
- Aarhus University (DK)
- Corresponding author
- Qin, Ping
- ORCID
- Qin, Ping
- Venue
- Journal of Psychiatric Research
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 45
- Issue
- 11
- Pages
- 1445-1452
- ISSN
- 0022-3956 (ISSN-L)
- OpenAlex
- W2112970068
- Cited by
- 157
- References
- 45
- Citations by year
- 2026: 10 · 2025: 11 · 2024: 17 · 2023: 10 · 2022: 7 · 2021: 14 · 2020: 13 · 2019: 6 · 2018: 9 · 2017: 8 · 2016: 8 · 2015: 10 · 2014: 8 · 2013: 21 · 2012: 3
- FWCI
- 11.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychiatric Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Sundhedsstyrelsen
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- suicide, mental illness, suicide risk, incidence rate ratio, population attributable risk, sex differences, age differences, recurrent depression, borderline personality disorder, schizophrenia, alcoholism, adjustment disorder, dementia, suicide prevention, socioeconomic adjustment
- MeSH terms
- Adult, Aged, Aging, Mental Disorders, Denmark, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Male, Middle Aged, Risk Factors, Sex Factors, Suicide, Prevalence, Case-Control Studies
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