Cited by 909Nerve injury and regenerationPhysical Activity and HealthExercise and Physiological Responses

The DOI matches its Crossref record; 94 of the 96 references it cites were found in a registry or an index.

A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor

Open access

Szuhany, Kristin L., Bugatti, Matteo, Otto, Michael W.·2015·Journal of Psychiatric Research

DOI 10.1016/j.jpsychires.2014.10.003PMC PMC4314337

Open this paper in CoChat — free account

Abstract

Consistent evidence indicates that exercise improves cognition and mood, with preliminary evidence suggesting that brain-derived neurotrophic factor (BDNF) may mediate these effects. The aim of the current meta-analysis was to provide an estimate of the strength of the association between exercise and increased BDNF levels in humans across multiple exercise paradigms. We conducted a meta-analysis of 29 studies (N = 1111 participants) examining the effect of exercise on BDNF levels in three exercise paradigms: (1) a single session of exercise, (2) a session of exercise following a program of regular exercise, and (3) resting BDNF levels following a program of regular exercise. Moderators of this effect were also examined. Results demonstrated a moderate effect size for increases in BDNF following a single session of exercise (Hedges' g = 0.46, p < 0.001). Further, regular exercise intensified the effect of a session of exercise on BDNF levels (Hedges' g = 0.59, p = 0.02). Finally, results indicated a small effect of regular exercise on resting BDNF levels (Hedges' g = 0.27, p = 0.005). When analyzing results across paradigms, sex significantly moderated the effect of exercise on BDNF levels, such that studies with more women showed less BDNF change resulting from exercise. Effect size analysis supports the role of exercise as a strategy for enhancing BDNF activity in humans, but indicates that the magnitude of these effects may be lower in females relative to males.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.jpsychires.2014.10.003

Cites

94 of 94 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

International physical activity questionnaire: 12-country reliability and validity
CRAIG, C. L., MARSHALL, A. L., SJ??STR??M, M., BAUMAN, A. E., BOOTH, M. L., AINSWORTH, B. E., PRATT, M., EKELUND, U., YNGVE, A., SALLIS, J. F., et al. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000078924.61453.fb · Cited by 21,619
Book Reviews: Statistical Methods for Meta-Analysis Larry V. Hedges and Ingram Olkin New York: Academic Press, 1985. xxii + 369 pp
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults
Garber, C. E., Blissmer, B., Deschenes, M. R., Franklin, B. A., Lamonte, M. J., Lee, I.-M., Nieman, D. C., & Swain, D. P. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318213fefb · Cited by 9,319 · cited 1×
“These included sex (expressed as % female), age, assay type (i.e., serum or plasma), diagnostic status, and exercise frequency (defined as greater than or equal to American College of Sports Medicine guidelines, Garber et al., 2011).”
Background
Untitled work
(2000) · Cited by 9,198
A power primer.
Cohen, J. (1992) · Psychological Bulletin · doi:10.1037//0033-2909.112.1.155 · Cited by 8,771
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,526
Methods of Meta-Analysis: Correcting Error and Bias in Research Findings
Schmidt, F. L., & Hunter, J. E. (2015) · doi:10.4135/9781483398105 · Cited by 5,542
Exercise training increases size of hippocampus and improves memory
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015950108 · Cited by 4,855
Statistical Methods for Meta-Analysis.
Freeman, P. R., Hedges, L. V., & Olkin, I. (1986) · Biometrics · doi:10.2307/2531069 · Cited by 4,840
Meta-Analytic Procedures for Social Research
Rosenthal, R. (1991) · doi:10.4135/9781412984997 · Cited by 4,635

Show all 96 references

Research works printed but not linked: 1

Cohen, 1992, power primer, Psychol Bull, 112, 155, 10.1037/0033-2909.112.1.155 · DOI · Paper page

Sorted by citations

Items 801–900 of 908

Mitochondrial health and longevity: intermittent fasting’s impact on cellular energy production
Ghosh, S., Singh, D. K. K., Mishra, P. K., Sinha, J. K., & Mitra, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-30060-8.00021-2 · Cited by 1
The effect of an acute bout of exercise on implicit sensorimotor adaptation
Beyraghi, Z., Arsenault-Lévesque, L., Desrosiers, J., Lepage, J., & Bernier, P. (2025) · Physiology & Behavior · doi:10.1016/j.physbeh.2025.115192
Acute Effects of Physical, Cognitive, and Combined Exercise on Executive Functions During Postural Challenge in Older Adults with Mild Cognitive Impairment
Giatagani, E., Δίπλα, Κ., Patikas, D., & Mademli, L. (2025) · Applied Sciences · doi:10.3390/app152312649
Effect of Proximity to Failure in Resistance Training on Circulating Levels of Neuroprotective Biomarkers
Benitez, B., Juber, M. C., Macarilla, C. T., Robinson, Z. P., Pelland, J. C., Remmert, J. F., Hinson, S. R., Visavadiya, N. P., & Zourdos, M. C. (2025) · Biology · doi:10.3390/biology14121756
The Effects of Cardiovascular Exercise on Corticospinal Excitability in People with Subacute StrokePreprint
Heras, B. D. L., Rodrigues, L., Cristini, J., Khalili, R., Tang, A., Eng, J. J., Fung, J., & Roig, M. (2025) · medRxiv · doi:10.64898/2025.12.02.25341471
Subjective memory complaints in Latin American older adults: Prevalence and risk factors
Caldichoury, N., Morales-Asencio, B., Coronado, J. C. S., Ripoll-Córdoba, D., Mendoza-Ruvalcaba, N. M., Quispe-Ayala, C., Camargo, L., Boza-Calvo, C., Apumayta, R. Q., Castellanos, C. E., et al. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251400666
Exercise biomarkers
Siebers, M., Bizjak, D. A., & Grau, M. (2025) · Advances in clinical chemistry · doi:10.1016/bs.acc.2025.11.003
EXERCÍCIO FÍSICO COMO ESTRATÉGIA DE PROMOÇÃO DA SAÚDE MENTAL EM CONTEXTOS DE TRABALHO PRECARIZADO: IMPLICAÇÕES PARA MOTORISTAS DE TRANSPORTE POR APLICATIVO
Rodrigues, N. S. M., & Pinto, R. F. (2025) · Conhecimento & Ciência eBooks · doi:10.29327/5747050.1-1
The impact of exercise intervention on hippocampal volume in the elderly: A meta-analysis
Zhang, H., Liu, J., & Zhang, W. (2025) · Medicine · doi:10.1097/md.0000000000046333
Additional file 1 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916915
Additional file 3 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916921
Additional file 4 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916924
Additional file 6 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916933
Additional file 1 of Effect of multicomponent exercise in cognitive impairment: a systematic review and meta-analysis
Venegas‐Sanabria, L. C., Cavero-Redondo, I., Martínez-Vizcaino, V., Cano-Gutierrez, C. A., & Álvarez-Bueno, C. (2022) · Figshare · doi:10.6084/m9.figshare.20374729
Additional file 7 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916939
Additional file 2 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916918
Additional file 5 of Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older – an umbrella review
Blomstrand, P., Tesan, D., Nylander, E. M., & Ramstrand, N. (2023) · Figshare · doi:10.6084/m9.figshare.23916930
Age-related cerebellar decline and integrated cerebellar tDCS-exercise therapy intervention: A narrative review from a neuroplastic perspective for fall prevention
Kang, D., Jang, H., & Yim, J. (2025) · Physical therapy rehabilitation science · doi:10.14474/ptrs.2025.14.4.655
A Case-Control Study of the Association Between Hypocholesterolemia and Depressive Symptoms in a Mexican Population from Los Altos Sur, Jalisco
Pérez-Sandoval, J. J., Limón-Fernández, H. A., Ortega-Morfín, M. F., Briseño-Ramírez, J., Rivera-León, E. A., & Sánchez‐Enríquez, S. (2026) · Psychiatry International · doi:10.3390/psychiatryint7010010
Combining physical and psychological interventions: impact of walking and self-affirmation on mental health outcomes in college students: a randomized controlled trial
Lee, Y. H., Kim, H., & Cho, H. (2026) · Current Psychology · doi:10.1007/s12144-025-08598-x · Cited by 1
Störungsspezifische Behandlung von Angsterkrankungen
Rausch, M., Pyrkosch, L., & Wehrheim, A. (2026) · Die Psychotherapie · doi:10.1007/s00278-025-00822-0
The Architectural Form of Desires. An Evolutionary Perspective on the Birth of Architecture
Ruzzon, D. (2026) · Springer series in design and innovation · doi:10.1007/978-3-032-11280-4_10
The association of Alzheimer’s disease-related SNPs with mild cognitive impairment susceptibility in the Chinese population
Xie, Z., Tu, W., Ye, X., Hua, L., Zhang, X., & Feng, N. (2026) · Scientific Reports · doi:10.1038/s41598-026-37309-0
Healing through movement: narrative review on exercise and neurological disorders
Essa, S. M., Kakar, A., Khosa, N. A., Ibrahim, I. A., Jovanovic, M., Mclaughlin, M. L., Ibrahim, M. M., & Riddle, K. (2025) · Asia-Pacific Journal of Surgical & Experimental Pathology · doi:10.32948/ajsep.2025.10.28
Natural synergistic interventions for depression: Voluntary wheel running and flavonoids
Kong, D., Li, D., Duan, Y., Chen, Y., & Li, T. (2026) · Behavioural Brain Research · doi:10.1016/j.bbr.2026.116088
Tai Chi Interventions for Slowing Cognitive Decline in Mild Cognitive Impairment: A Review of Randomized Controlled Trials
Branscom, G. A., Vama, B., Bane, B., Sun, M., & Liu, J. (2026) · Cureus · doi:10.7759/cureus.103588
The Effect of High-Intensity Interval Training on Neuroplasticity-Related Proteins in the Cerebrum of Postnatally Growth-Restricted Mice
Kim, S.-H., Quinn, M. A., Ananyev, J., McPeek, A. C., Leszczynski, E. C., & Ferguson, D. J. P. (2026) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003964
Mental health and sleep quality across different physical activity intensities: A cross-sectional epidemiological analysis
Beretta, V. S., do Prado, W. L., Tebar, W. R., Mota, J. A. P. S., Antunes, E. P., Furuta, D. T., Morelhao, P. K., Casonatto, J., Brazo‐Sayavera, J., Ferrari, G., et al. (2026) · Acta Psychologica · doi:10.1016/j.actpsy.2025.106178
Sleep deprivation and learning & memory impairments: The modulating effects of exercise and complementary medicine
Salari, M., Rajizadeh, M. A., & Sheibani, V. (2026) · Behavioural Brain Research · doi:10.1016/j.bbr.2026.116131
Depression across the menopausal stages in the United Arab Emirates: prevalence and risk factors
Vohra, S., Gulati, A., Vohra, S., & Sreejith, A. (2026) · Frontiers in Global Women s Health · doi:10.3389/fgwh.2026.1702610
The role of prehabilitation in improving brain health and cognition after chemotherapy in patients with colorectal cancer: Study protocol of the Chemo Brain Prehab Project
Hoad, K. L., Ton, C., Williamson, D., Subar, D. A., Nuttall, H. E., & Gaffney, C. J. (2026) · PLOS One · doi:10.1371/journal.pone.0341996
Neurotrophins Plasma Levels Kinetics in Ischemic Stroke Patients—Potential Relation to Outcomes
Opiła, R., Łuczkowska, K., Paczkowska, E., Nowacki, P., Peregud-Pogorzelski, J. W., & Machaliński, B. (2026) · Neurology International · doi:10.3390/neurolint18030051
ASSOCIAÇÃO ENTRE OS NÍVEIS DE ATIVIDADE FÍSICA E ANSIEDADE, ESTRESSE E DEPRESSÃO EM PACIENTES COM TRANSTORNO OBSESSIVO COMPULSIVO
Leão, M., Leão, G. J. M., Damasceno, V. D. O., & Costa, A. (2025) · Acta Biologica Brasiliensia. · doi:10.18554/acbiobras.v8i2.8756
Contributions of yoga and aerobic exercise to acute changes in state affect, circulating BDNF and eCB concentrations, and memory
Leri, J., Crombie, K. M., Malloy, L. T., Wang, L., Broski, P., & Cisler, J. M. (2026) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2026.107817
Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease
Páez-García, S., Alvarado, E., Cuevas, A., Valverde, L., Salinas, E., O'Hara-Veintimilla, K., Rodríguez-Oroz, M., & Borda, M. G. (2026) · Neuroprotection · doi:10.1002/nep3.70032
Associations of long-term PM2.5 exposure and physical activity on sleep: a cross-sectional analysis
Zhang, S., Li, Y., You, Y., Ke, L., Ma, X., & Liu, J. (2026) · BMC Public Health · doi:10.1186/s12889-026-26824-4
Acute exercise increases BDNF and short-term memory in healthy adults
Tommasini, E., Turco, E., Cancer, A., Colautti, L., Iannello, P., Antonietti, A., Missaglia, S., Bosio, A., & Tavian, D. (2026) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2026.108160
Faisabilité et comparaison d'un entrainement aérobie de type continu ou intermittent sur les capacités physiologiques, cognitives et la qualité de vie, chez des personnes âgées présentant un trouble neurocognitif majeur associé à la maladie d'Alzheimer
Enette, L. (2019) · theses.fr (ABES) · doi:10.70675/1ad1a02ez8eebz4234z9bdfzf1e991390f85
Effect of age, vascular parameters, physical activity, and cardiorespiratory fitness on executive performances : role of cerebral oxygenation
Goenarjo, R. A. (2020) · theses.fr (ABES) · doi:10.70675/51bb5024z5364z408bzb15ez3690d9f7f17b
Effet d'un entrainement moteur sur les réseaux moteurs spinaux en développement chez la souris nouveau-née : et analyses cellulaire et comportementale de la modulation développementale des récepteurs métabotropiques du glumate dans les motoneurones lombaires
Quilgars, C. (2021) · theses.fr (ABES) · doi:10.70675/4b84b239z423bz46aaza3eaz54db476be688
Effet d’une stimulation enrichie sur le fonctionnement cognitif de personnes Alzheimer à un stade modéré et des adultes présentant un déficit cognitif léger.
Ayed, I. B. (2021) · theses.fr (ABES) · doi:10.70675/cfcbef75zedfdz48dez80f3zd2a2d4cabbd6
Le yoga dans la rééducation des patients atteints de pathologies du système nerveux central et plus particulièrement d'accident vasculaire cérébral
Caron, R. L. D. (2023) · theses.fr (ABES) · doi:10.70675/500d14a7z5ff5z4511za96eza2887ca8cfea
Digital interventions to improve cognitive complaints among patients with breast cancer : implementation, follow-up and promotion of the Cog-Stim research program
Binarelli, G. (2023) · theses.fr (ABES) · doi:10.70675/d8607559z4e58z45b1z9bb1z0690611353c9
Heart failure rehabilitation through virtual reality: an evidence-based rapid review
Rios-García, W., Barrientos-Ventura, E., Butrón-Verástegui, V. E., Oriundo-Arbizu, D. E., Velasquez-Taipe, K. A., & Rios-Garcia, A. A. (2026) · Journal of Public Health · doi:10.1007/s10389-026-02751-x
Sleep, movement, and marks: exploring the relationship between sleep quality, physical activity, and academic performance in male university students
Alghadier, M. (2026) · PeerJ · doi:10.7717/peerj.21154
Effectiveness of different types of exercise therapy in improving post-stroke depression: a systematic review and network meta-analysis
Li, W., Li, L., Zhao, S., Wang, C., Jin, Y., & Ji, G. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1828873
Longitudinal association between the weekend warrior physical activity pattern and cognitive function trajectories among middle-aged and older Chinese adults
Liu, M., & Li, Y. (2026) · Archives of Public Health · doi:10.1186/s13690-026-01955-7
Submaximal Unilateral Arm Cycling Produces Transient but Not Sustained Changes in Corticospinal Excitability in the Homologous Muscles of the Non-Exercised Limb
Rahmani, H., Amoozi, H., Refai, I. S. A. A., & Power, K. E. (2026) · Brain Sciences · doi:10.3390/brainsci16050514
Context-dependent modulation of LTP and BDNF/TrkB signaling in the dentate gyrus following combined progressive aerobic and rotarod training in male wistar rats
Sadeghi, M., Komaki‬, A., & Nazem, F. (2026) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2026.05.014
Integrating vascular, cognitive, and mental health benefits of exercise in obese women across menopause: a review
Jang, J., & Park, H. (2026) · Exploration of Medicine · doi:10.37349/emed.2026.1001409
Effects of spot marching and resistance exercise on cardiovascular autonomic function and exercise performance in post-COVID-19 individuals: A randomized controlled trial
Kluayhomthong, S., Sathaporn, N., Panwong, W., Buttagat, V., Pipatbanjong, P., Wichiankul, C., Samran, A., Praykaew, N., Seubjui, T., Akaranavaseri, S., et al. (2026) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2026.06.001
A review of the effects of physical exercise on neuroplasticity and their relevance in management of mental disorder
Mayfield, N. (2026) · BJPsych Advances · doi:10.1192/bja.2026.10217
Physiological Adaptations and Serum-Based Biomarker Dynamics During Multimodal Rehabilitation in Chronic Pain: Analysis of a Prospective Cohort Study
Meinzer, M., Bassler, M., Kessemeier, F. M., Webering, C., Neumann, D., Bähre, H., Lichtinghagen, R., Rhein, M., Achenbach, J., Gutenbrunner, C. M., et al. (2026) · Biomolecules · doi:10.3390/biom16060841
The effects of Tai Chi practice on plantar tactile sensation and ankle proprioception in older adults with peripheral neuropathy
Zhao, Q., Wang, Q., Liu, Z., Song, Q., Zhu, X., & Song, Q. (2026) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2026.1780973
Enhancing effects of diphenyl diselenide and β-hydroxy β-methylbutyrate combined with exercise on neuroprotection, memory, mitochondrial function, muscle function, and inflammation regulation in older adults and age-related diseases
Huang, R., & Pang, W. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1770666
Integrative NeuroSomatic Therapy: a neuroscience-informed framework for threshold-based transformation
Hadlock, G. (2026) · Body Movement and Dance in Psychotherapy · doi:10.1080/17432979.2026.2689954
Exercise- and dietary pattern-based lifestyle interventions and neurocognitive function in adults: a Bayesian multilevel network and dose–response meta-analysis
Jiao, M., Li, Q., Liang, H., Zhang, B., Li, M., Li, J., Harun, M. T., & Wen, F. (2026) · Journal of Neurology · doi:10.1007/s00415-026-13918-7
Effects of exercise interventions on core health outcomes in patients with SLE: systematic review and meta-analysis
He, Z., Jia, S., Chen, M., Shi, X., Hu, L., Li, F., Shi, H., Nieman, D. C., & Shi, Y. (2026) · Lupus Science & Medicine · doi:10.1136/lupus-2026-002027
Joint Associations of Meditation and Physical Activity with Depression and Anxiety Symptoms in US Adults: NHIS 2022
Wang, Y. (2026) · Mindfulness · doi:10.1007/s12671-026-02912-9
Diet, Sleep, and Physical Activity in Children and Adolescents With Depression: An Umbrella Review of Systematic Reviews
Campisi, S. C., Luca, I. D., Zilio, M., Dayal, A., Kinzel, E., & Korczak, D. J. (2026) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2026.04.018
Effect of physical exercise on cognitive outcomes in patients with subjective cognitive decline: A systematic review
Siddiqui, H. A., Sundus, H., Khan, S. A., Azharuddin, M., & Fatima, N. (2026) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2026.07.016
Association of plasma irisin levels with amyloid burden in the Alzheimer's disease spectrum
Jung, Y. H., Lee, E. S., Park, Y. J., Lee, S., Chung, S. J., Lim, J. J., Kim, S. W., Kang, H. J., Eo, J. S., Oh, K., et al. (2026) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70418
Advancements in non-pharmaceutical interventions for Alzheimer’s disease management: an update review
Chen, J., & Zhang, Z. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1855269
The prognostic potential of circulating BDNF levels and its polymorphisms in age-related cognitive impairment and neurodegeneration
Tulupova, T. V., Vedunova, M. V., & Mitroshina, Е. V. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1901527
The Psychological Effects of Exercise: Neurobiological Mechanisms and Clinical Applications
Msheik, A., Peralta, R., Mokdad, Z. A., Hussein, M., Illeyan, A., Alsaad, N., Sada, F. A., Al-Maadhadi, M., Hajjali, A. A., Alkubaisi, A., et al. (2026) · IntechOpen eBooks · doi:10.5772/intechopen.1016110
Effects of acute cardiovascular exercise and coordinative motor activity on verbal functions and attention
Fischer, M., Kraft, V. S., & Hermsdörfer, J. (2026) · Cognitive Processing · doi:10.1007/s10339-026-01380-2
Acute effects of sports with different metabolic loads on serum irisin, BDNF, and NRF2 levels and cognitive performance in sedentary young adults: a comparative analysis of basketball and tennis protocols
Akkaya, C. C., & Ceylan, C. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1911856
Changes in salivary brain-derived neurotrophic factor following a standardized eating task in community-dwelling older adults: a cross-sectional study
Mino, T., Kurosaki, Y., Maeda, S., Maekawa, K., Takahashi, N., Nezu, R., Nishiura, K., Yamano, E., Shiramizu, M., Kawamoto, A., et al. (2026) · Odontology · doi:10.1007/s10266-026-01526-w
Exercise-induced attenuation of the lateral habenula: a multi-axial quantitative synthesis of circuit-level resilience in depression
Vorkapic, C. F., Ferreira, D. M., Coelho, R. R., Wiech, M., & Dantas, E. H. M. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1887822
Exercise-Induced Metaplasticity: Breaking the Addiction Cycle in Methamphetamine Use Disorder
Wang, D., Jin, J., Hillman, C. H., & Chang, Y. (2026) · Sports Medicine - Open · doi:10.1186/s40798-026-01088-9
Enhancing brain health through resistance exercise: the effect of set number and intensity on brain- derived neurotrophic factor in older adults
Chen, H.-T., Chen, K.-H., Lin, C., & Chung, Y.-C. (2026) · PeerJ · doi:10.7717/peerj.21595
Evaluating the Neuroprotective Effects of Personalized Ayurvedic Integrative Therapy on Cognitive Function, Brain Connectivity, and Neuroinflammatory Biomarkers in Early Neurodegenerative Disorders: A Prospective Clinical Study
Kumar, D. R., Raj, A., & Shiromani, D. T. (2026) · International Journal for Neurology and Neuroscience · doi:10.66715/ijnn/2026.v2.i1.106117
Rethinking exercise dose for cognitive ageing: a systematic review and meta-analysis of physical dose and cognitive–motor demands
Bartolo, D. D., Baleca, L., Salera, C., & Lucidi, F. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1906526
Voluntary Exercise and Hippocampal Memory Enhancement: Decoding the Molecular Blueprint
Razazpour, F., Golkar, A., Heidari, M., Seyedi, F., Hedayati‐Moghadam, M., & Baghcheghi, Y. (2026) · Journal of Molecular Neuroscience · doi:10.1007/s12031-026-02577-y
Beyond High-Intensity Interval Training: Optimizing Endurance Training Intensity Distribution to Enhance Warfighter Aerobic Fitness
Nevin, J., Blacker, S. D., & Orr, R. M. (2026) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000997
Divergent intestinal barrier and neuroimmune responses to supervised exercise across fibromyalgia, irritable bowel syndrome, and their comorbidity phenotypes: a prospective interventional study
Bianco, A., Russo, F., Prospero, L., Laselva, G., Grasso, M., D’Attoma, B., Verrelli, N., Ignazzi, A., Franco, I., Grazioli, E., et al. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1912788
Association Between Serum BDNF and S100 B Levels in Community-Dwelling Older Adults
Orihashi, R., Shiraishi, T., Murakawa‐Hirachi, T., Tateishi, H., Kunitake, Y., Kunitake, H., & Mizoguchi, Y. (2026) · Biological Research For Nursing · doi:10.1177/10998004261479322
Touch Restriction Versus Free‐Play Small‐Sided Games in Soccer: Acute Effects on Serum BDNF, Executive Function, and Technical Actions
Bırıncı, Y. Z., Pancar, S., Soylu, Y., Sarandöl, E., Şimşek, H., Şahin, Ş., & Rumpf, M. C. (2026) · European Journal of Sport Science · doi:10.1002/ejsc.70242
Title: Gene expression, neuroinflammation, and neural plasticity in type 2 diabetes: Translational insights from exercise and cognitive modulation
Diniz, C. G., Bento-Torres, N. V. O., da Costa, E. R., Magalhães, N. G. D. M., de Melo, M. A. D., Pereira, P. D. C., Carvalho, J. P. R., Magno, G. M., Bento‐Torres, J., Sosthenes, M. C. K., et al. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106922
Functional and Neurotrophic Outcomes After Physical Therapy and Injection-Based Treatments for Rotator Cuff Tendinopathy: The FORTIS Pilot Randomized Trial
Pawłuś, N., Turkiewicz, S., Lesman, J., Gabryelska, A., Domżalski, M. E., & Kanak, M. (2026) · Orthopaedic Journal of Sports Medicine · doi:10.1177/23259671261468532
Associations between high perceived stress, inflammatory proteins, and BDNF: a cross-sectional study of young adult females in Shanghai, China
Gao, P., Zhang, H., Xiao, X., Jiang, W., Tan, Y., & Gu, X. (2026) · Stress · doi:10.1080/10253890.2026.2723346
Effects of Exercise Intensity on Peripheral Oxidative Stress and Brain 3-Nitrotyrosine and Brain-Derived Neurotrophic Factor Levels in Rats
Ohno, Y. (2026) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2026.168009
Effects of Exercise Interventions on Peripheral Brain-Derived Neurotrophic Factor: An Umbrella Meta-Analysis Across Clinical and Healthy Populations
Süleymanoğulları, M., Eyipınar, C. D., Muntean, R. I., & Ceylan, H. İ. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15176733
Current perspectives on non-pharmacological approaches to cognitive impairment
Gileva, E. A., Коваленко, Е. А., Makhnovich, E. V., Osinovskaya, N. A., & Bogolepova, A. N. (2026) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202612608159
Exercise-induced neuropeptidergic and neurochemical neuroadaptation in stress regulation and emotional disorders
Wang, Z., 谭支内, Zhang, Y., Li, Y., Lin, J., Xu, Y., Li, Y., & Chen, T. (2026) · Acta Neurologica Belgica · doi:10.1007/s13760-026-03168-9
Effects of exercise on depression, anxiety, and physiological/biochemical markers in college students with depressive symptoms: A three-level meta-analysis
魏如冰, Li, J., Fan, W., & Zhang, L. (2026) · Acta Psychologica · doi:10.1016/j.actpsy.2026.107763
Feasibility study of the Strength in Numbers program in secondary school classroomsPreprint
Robinson, K. J., Lubans, D. R., Mavilidi, M. F., Parkes, R., Nihill, G. F., Leahy, A. A., Eather, N., Ersozlu, Z., Tse, A. C. Y., & Riley, N. (2026) · Research Square · doi:10.21203/rs.3.rs-10965522/v1
Primitive-Reflex Profiling After Sport-Related Concussion: An Athlete-Centered Framework for Testing a Candidate Behavioral State Marker
Stephens‐Sarlós, E., Stephens, P., & Szabó, A. (2026) · Brain Sciences · doi:10.3390/brainsci16090968
High-intensity interval training as a cognitive enhancement strategy for executive function in overweight female university Students
Li, L., & Sun, L. F. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1886108
The Inflammatory Indicator IL-6 and BDNF Levels in Male Fitness Athletes and Their Relationship with Acute Stress Disorder: A Case-Control Study
Asadi, T., Mohammadi, M. R., & Mostafavi, S. (2025) · Asian Journal of Sports Medicine · doi:10.5812/asjsm-169563
Increasing daily step count in mild cognitive impairment: a 12-month randomised controlled trial
Jamka, M., Makarewicz-Bukowska, A., Pawlak, M. A., Popek, J., Mądry, E., Krzyżanowska-Jankowska, P., Karmelita‐Katulska, K., Miśkiewicz-Chotnicka, A., Kurek, S., Trepanowski, R., et al. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1958222
Aquatic Interventions for Children and Adolescents With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Motor, Sleep, Executive Function, and Adaptive Measures
Ziab, H. M., Mazbouh, R., Shami, A. A. A., Singh, K., & Nashwan, A. J. (2026) · Cureus · doi:10.7759/cureus.116809
Aerobic exercise, whey protein, and creatine in adolescents: implications for performance, recovery, immunometabolic adaptation, and muscle–bone–brain crosstalk
Qin, K., & Wu, J. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1915252
Sculpting the developing brain: a review of neural mechanisms linking physical activity to executive function and emotion regulation in youth
Wen, D.-T., Lin, Y., Sun, J.-Y., Lv, S.-Z., Ji-Ying, W. A. N. G., Tian-shuo, Y., & Zhu, D.-Y. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1865879
Effects of exercise interventions on fundamental motor skills in children and adolescents with autism spectrum disorder: a meta-analysis with meta-regression analyses of randomized controlled trials
Su, J., Li, L., Wang, Y., & Fan, T. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1954728
The effects of sports activity on cognition in nine- and ten-year-old children
Wallace, A. L., Forseth, B. M., Sullivan, R. M., Wade, N. E., Stinson, E. A., & Lisdahl, K. M. (2026) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617726102239
Comparative Effects of Acute HIIE and MICE on Executive Function, Prefrontal Oxyhaemoglobin Responses, and Related Biomarkers in Sedentary Young Adults: A Randomized Crossover Trial
Huang, J., Huang, J., Liu, Z., & 杨, 欣. (2026) · Brain Sciences · doi:10.3390/brainsci16101054
Linking childhood emotional maltreatment to social media addiction: a network perspective on executive function and physical activity
Chen, Y., Wang, N., Yuan, A., Xiang, L., Long, S., Luo, J., & Liu, Y. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1945221
Exercise as a Longevity Matrix: A Narrative Review
Arabzadeh, E., Rostamkhani, F., Shirvani, H., & Wong, A. (2026) · SN Comprehensive Clinical Medicine · doi:10.1007/s42399-026-02764-3
Mechanisms of Exercise Training in Ameliorating Cognitive Function in Patients With Depression: A Narrative Review of Molecular Targets and Clinical Prescriptions
Guo, Z., Dong, L., Lin, J., Duan, Y., Liu, W., Jiang, W., Liu, C., Jia, S., Song, Y., Ding, F., et al. (2026) · European Journal of Sport Science · doi:10.1002/ejsc.70272

Authors: Szuhany, K. L., Bugatti, M., & Otto, M. W.
Affiliations: Boston University (US)
Corresponding author: Szuhany, Kristin L.
ORCID: Szuhany, Kristin L.
Bugatti, Matteo
Otto, Michael W.
Venue: Journal of Psychiatric Research
Publisher: Elsevier BV
Published: 2015-01
Volume: 60
Pages: 56-64
ISSN: 0022-3956 (ISSN-L)
DOI: 10.1016/j.jpsychires.2014.10.003
PMC: PMC4314337
OpenAlex: W2047262956
Cited by: 909
References: 96
Citations by year: 2026: 113 · 2025: 104 · 2024: 83 · 2023: 90 · 2022: 77 · 2021: 99 · 2020: 75 · 2019: 76 · 2018: 64 · 2017: 63 · 2016: 49 · 2015: 15
FWCI: 4.84
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychiatric Research (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health (F31 MH100773)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Keywords: physical activity, brain-derived neurotrophic factor, single-session exercise, regular exercise, sex differences, cognitive function, mood, neuroplasticity
MeSH terms: Adult, Age Factors, Female, Humans, Male, Motor Activity, Sex Factors, Time Factors, Exercise, Brain-Derived Neurotrophic Factor

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks