The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cardiovascular activity and the antibody response to vaccination
Open accessAbstract
Objective To examine the relationship between cardiovascular activity in response to acute psychological stress and the antibody response to vaccination. Methods Fifty-seven healthy participants were vaccinated with the trivalent influenza vaccine and meningococcal A+C polysaccharides. Antibody levels were measured at baseline and 5-weeks post-vaccination. Cardiovascular activity was measured at rest, during, and following a mental arithmetic stress task in 54 participants. Results Participants demonstrating a fourfold increase in antibody titre to the A/Panama and B/Shangdong influenza strains and to meningococcal A showed greater blood pressure reactions toward the end of the acute stress task. In addition, there was some evidence of delayed diastolic blood pressure recovery in those who were responders to A/Panama and B/Shangdong influenza strains. Conclusion The present results suggest that heightened cardiovascular reactivity to stress and delayed recovery may not necessarily be detrimental to all aspects of health and may be associated with an enhanced immune response to antigen challenge.
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Acute stress enhances antiviral defenses.
“For example, whereas acute stress has been found to enhance antiviral defenses”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Phillips, Carroll, Burns, & Drayson, 2009
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Cites
Chronic Stress Modulates the Immune Response to a Pneumococcal Pneumonia Vaccine
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“(4)), rubella (5), and pneumococcus (6).”
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Slavich, G. M., & Irwin, M. R. (2014) · Psychological Bulletin · doi:10.1037/a0035302 · Cited by 2,206
Blunted cardiovascular reactivity relates to depression, obesity, and self-reported health
Phillips, A. C. (2011) · Biological Psychology · doi:10.1016/j.biopsycho.2010.03.016 · Cited by 126
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Metadata
- Authors
- Phillips, A. C., Carroll, D., Burns, V. E., & Drayson, M.
- Affiliations
- University of Birmingham (GB)
- Corresponding author
- Phillips, Anna C.
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2009-07
- Volume
- 67
- Issue
- 1
- Pages
- 37-43
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2066057605
- Cited by
- 31
- References
- 1
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2020: 2 · 2019: 4 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Institutional Research Archive (University of Birmingham) (acceptedVersion)
- Stirling Online Research Repository (University of Stirling) (submittedVersion, cc-by-nc-nd)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Keywords
- cardiovascular reactivity, psychological stress, antibody response, vaccination, influenza vaccination, meningococcal polysaccharide vaccine, blood pressure, immune response, stress and immunity
- MeSH terms
- Antibodies, Enzyme-Linked Immunosorbent Assay, Humans, Hypertension, Influenza, Human, Influenza Vaccines, Male, Polysaccharides, Bacterial, Psychology, Surveys and Questionnaires, Stress, Psychological, Vaccination, Meningococcal Vaccines, Young Adult
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