Relations between sleep, fatigue, and health-related quality of life in individuals with insomnia
Open accessAbstract
Objective This study explored the relations between sleep, fatigue, and health-related quality of life in a sample of individuals with chronic insomnia.Methods A total of 160 adults meeting the diagnostic criteria for chronic insomnia underwent three nights of polysomnography (PSG) and completed sleep diaries and questionnaires assessing daytime functioning including fatigue and health-related quality of life.Results A cluster analysis was conducted based on PSG-defined sleep disturbances and fatigue severity. A four-cluster solution (R(2)=0.68) was found, classifying individuals as having either (a) both severe sleep disturbance and severe fatigue (n=15); (b) severe sleep disturbance but milder fatigue (n=15); (c) milder sleep disturbance but severe fatigue (n=68); or (d) both milder sleep disturbance and milder fatigue (n=61). Health-related quality of life was lower in both clusters with severe fatigue compared to those with milder fatigue and was further decreased when severe sleep disturbances were present. Relations between several indicators of fatigue and health-related quality of life were then examined using factor analysis in order to identify different domains of impairment. A three-factor structure was selected, suggesting that daytime symptoms can be classified as relating to fatigue, physical health, or mental health. These different subtypes of daytime impairment were predicted by distinct sets of variables.Conclusion More severe fatigue is not necessarily related to poorer PSG-defined sleep but appears associated with greater impairment in health-related quality of life. Fatigue and health-related quality of life appear to be distinct but interrelated constructs.
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Sleep quality is an antecedent of fatigue.
“These findings support the notion that sleep quality are antecedents of fatigue.”
From A serial mediation model of social media addiction and college students' academic engagement: the role of sleep quality and fatigue (2023) · cites this paper as [43]
The Discussion (page unavailable) says subjective sleep quality predicted fatigue in individuals with insomnia, supporting an association. But the paper does not establish that sleep quality temporally precedes or causes fatigue; the Introduction notes that daytime tiredness may itself influence subjective sleep ratings. (LLM, conf=0.86)
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- Authors
- Fortier-Brochu, É., Beaulieu-Bonneau, S., Ivers, H., & Morin, C. M.
- Affiliations
- Université Laval (CA)
- Corresponding author
- Morin, Charles M.
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2010-11
- Volume
- 69
- Issue
- 5
- Pages
- 475-483
- ISSN
- 0022-3999 (ISSN-L)
- PMC
- PMC2958173
- OpenAlex
- W1984894406
- Cited by
- 144
- References
- 29
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 17 · 2023: 13 · 2022: 13 · 2021: 17 · 2020: 8 · 2019: 5 · 2018: 3 · 2017: 2 · 2016: 8 · 2015: 7 · 2014: 7 · 2013: 8 · 2012: 8
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (MH#60413, R01MH060413)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Keywords
- chronic insomnia, fatigue, health-related quality of life, sleep disorders, daytime dysfunction, daytime functioning, polysomnography, sleep diary, clustering, daytime symptoms
- MeSH terms
- Adult, Aged, Chronic Disease, Fatigue, Female, Health Status, Health Surveys, Humans, Sleep Initiation and Maintenance Disorders, Male, Mental Health, Middle Aged, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Sleep, Cluster Analysis, Polysomnography
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