Cost-utility of collaborative care for major depressive disorder in primary care in the Netherlands

Goorden, Maartje; Huijbregts, Klaas M.L.; van Marwijk, Harm W.J.; Beekman, Aartjan T.F.; van der Feltz-Cornelis, Christina M.; Hakkaart-van Roijen, Leona

doi:10.1016/j.jpsychores.2015.06.006

Cited by 26Health Systems, Economic Evaluations, Quality of LifeMental Health Treatment and AccessTreatment of Major Depression

Cost-utility of collaborative care for major depressive disorder in primary care in the Netherlands

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Goorden, Maartje, Huijbregts, Klaas M.L., van Marwijk, Harm W.J., Beekman, Aartjan T.F., van der Feltz-Cornelis, Christina M., Hakkaart-van Roijen, Leona·2015·Journal of Psychosomatic Research

DOI 10.1016/j.jpsychores.2015.06.006

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Abstract

Objective Major depression is a great burden on society, as it is associated with high disability/costs. The aim of this study was to evaluate the cost-utility of Collaborative Care (CC) for major depressive disorder compared to Care As Usual (CAU) in a primary health care setting from a societal perspective.Methods A cluster randomized controlled trial was conducted, including 93 patients that were identified by screening (45-CC, 48-CAU). Another 57 patients were identified by the GP (56-CC, 1-CAU). The outcome measures were TiC-P, SF-HQL and EQ-5D, respectively measuring health care utilization, production losses and general health related quality of life at baseline three, six, nine and twelve months. A cost-utility analysis was performed for patients included by screening and a sensitivity analysis was done by also including patients identified by the GP.Results The average annual total costs was €1131 (95% C.I., €-3158 to €750) lower for CC compared to CAU. The average quality of life years (QALYs) gained was 0.02 (95% C.I., -0.004 to 0.04) higher for CC, so CC was dominant from a societal perspective. Taking a health care perspective, CC was less cost-effective due to higher costs, €1173 (95% C.I., €-216 to €2726), of CC compared to CAU which led to an ICER of 53,717 Euro/QALY. The sensitivity analysis showed dominance of CC.Conclusion The cost-utility analysis from a societal perspective showed that CC was dominant to CAU. CC may be a promising treatment for depression in the primary care setting. Further research should explore the cost-effectiveness of long-term CC.Trial registration Netherlands Trial Register ISRCTN15266438.

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Cost-utility of collaborative care for the treatment of comorbid major depressive disorder in outpatients with chronic physical conditions. A randomized controlled trial in the general hospital setting (CC-DIM)
Goorden, M., Feltz-Cornelis, C. M. V. D., van Steenbergen-Weijenburg, K. M., Horn, E. K., Beekman, A. T. F., & Roijen, L. H. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s134008 · Cited by 9 · see citing works
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Cost-effectiveness of collaborative care for the treatment of major depressive disorder in primary care. A systematic review
van Steenbergen-Weijenburg, K. M., Feltz-Cornelis, C. M. V. D., Horn, E. K., van Marwijk, H., Beekman, A. T. F., Rutten, F., & Roijen, L. H. (2010) · BMC Health Services Research · doi:10.1186/1472-6963-10-19 · Cited by 89 · see citing works
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Cost-effectiveness of a care manager collaborative care programme for patients with depression in primary care: economic evaluation of a pragmatic randomised controlled study
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Cost-effectiveness analysis of a collaborative care programme for depression in primary care
Aragonès, E., López-Cortacans, G., Sánchez, E., Piñol, J. L., Caballero, A., Salvador‐Carulla, L., & Hita, J. M. C. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.01.021 · Cited by 23 · see citing works

Authors: Goorden, M., Huijbregts, K. M. L., van Marwijk, H. W. J., Beekman, A. T. F., van der Feltz-Cornelis, C. M., & Hakkaart-van Roijen, L.
Affiliations: Erasmus University Rotterdam (NL)
Amsterdam Public Health (NL)
Corresponding author: Goorden, Maartje
ORCID: Beekman, Aartjan T.F.
Venue: Journal of Psychosomatic Research
Publisher: Elsevier BV
Published: 2015-10
Volume: 79
Issue: 4
Pages: 316-323
ISSN: 0022-3999 (ISSN-L)
DOI: 10.1016/j.jpsychores.2015.06.006
OpenAlex: W1850166177
Cited by: 26
References: 31
Citations by year: 2025: 1 · 2024: 4 · 2023: 1 · 2022: 1 · 2021: 7 · 2020: 4 · 2018: 2 · 2017: 6
FWCI: 6.42
Type: journal article
Language: en
Open access: green
pure.eur.nl
Licence: other-oa
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychosomatic Research (publishedVersion)
Research portal (Tilburg University) (publishedVersion)
PubMed (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
VU Research Portal (publishedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Pure Amsterdam UMC (submittedVersion)
Research Explorer (The University of Manchester) (submittedVersion)
VU Research Portal (submittedVersion)
Funders: Depression Initiative
Topics: Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords: collaborative care, major depressive disorder, cost-utility analysis, cost-effectiveness, primary care, usual care, quality-adjusted life years, health care utilization, production losses, health-related quality of life, depression screening, societal perspective
MeSH terms: Cost-Benefit Analysis, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Netherlands, Primary Health Care, Quality of Life

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Cost-utility of collaborative care for major depressive disorder in primary care in the Netherlands

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