Comparative Effectiveness of Collaborative Chronic Care Models for Mental Health Conditions Across Primary, Specialty, and Behavioral Health Care Settings: Systematic Review and Meta-Analysis
Abstract
OBJECTIVE: Collaborative chronic care models (CCMs) improve outcome in chronic medical illnesses and depression treated in primary care settings. The effect of such models across other treatment settings and mental health conditions has not been comprehensively assessed. The authors performed a systematic review and meta-analysis to assess the comparative effectiveness of CCMs for mental health conditions across disorders and treatment settings. METHOD: Randomized controlled trials comparing CCMs with other care conditions, published or in press by August 15, 2011, were identified in a literature search and through contact with investigators. CCMs were defined a priori as interventions with at least three of the six components of the Improving Chronic Illness Care initiative (patient self-management support, clinical information systems, delivery system redesign, decision support, organizational support, and community resource linkages). Articles were included if the CCM effect on mental health symptoms or mental quality of life was reported. Data extraction included analyses of these outcomes plus social role function, physical and overall quality of life, and costs. Meta-analyses included comparisons using unadjusted continuous measures. RESULTS: Seventy-eight articles yielded 161 analyses from 57 trials (depression, N=40; bipolar disorder, N=4; anxiety disorders, N=3; multiple/other disorders, N=10). The meta-analysis indicated significant effects across disorders and care settings for depression as well as for mental and physical quality of life and social role function (Cohen's d values, 0.20-0.33). Total health care costs did not differ between CCMs and comparison models. A systematic review largely confirmed and extended these findings across conditions and outcome domains. CONCLUSIONS: CCMs can improve mental and physical outcomes for individuals with mental disorders across a wide variety of care settings, and they provide a robust clinical and policy framework for care integration.
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Screening and behavioral health programs integrated into routine practice can mitigate the deleterious effects of alcohol use disorder, substance abuse, and depression in patients with chronic liver disease.
“Screening and behavioral health programs integrated into routine practice can mitigate the deleterious effects of such illnesses but have not been adopted in hepatology practices.”
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Behavioral health interventions integrated into routine clinical practice for chronic diseases have been shown to achieve the triple aim of improved health outcome, better quality of care, and reduced health care costs.
“Behavioral health interventions integrated into routine clinical practice for chronic diseases have been shown to achieve the triple aim of improved health outcome, better quality of care, and reduced health care costs.1, 2”
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The chronic care model has been shown in multiple randomized trials to improve physical and mental health outcomes across different mental disorders with little to no added cost.
“The chronic care model has been shown in multiple randomized trials to improve physical and mental health outcomes across different mental disorders, with little to no added cost 42 .”
From Measuring and improving the quality of mental health care: a global perspective (2018) · cites this paper as [42]
Collaborative care models have demonstrated to be effective and cost-effective in the treatment of depression.
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An introduction to implementation science for the non-specialist
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Self-citationThe Rise of Primary Care Physicians in the Provision of US Mental Health Care
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Self-citationIntegrated Care for Older Adults with Serious Mental Illness and Medical Comorbidity
Bartels, S. J., DiMilia, P. R., Fortuna, K. L., & Naslund, J. A. (2017) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2017.10.012 · Cited by 86 · see citing works
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“…the streams of costs and benefits are likely to be quite different from conventional programs that operate more independently as silos of behavioral health care (Buntin, Burke, Hoaglin, & Blumenthal, 2011; Hutubessy et al., 2002; Mechanic, 2012; Torres-Edejer et al., 2003; Woltmann et al., 2012).”
BackgroundVenlafaxine Extended-Release for Depression Following Spinal Cord Injury
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- Authors
- Woltmann, E., Grogan-Kaylor, A., Perron, B., Georges, H., Kilbourne, A. M., & Bauer, M. S.
- Affiliations
- Harvard University (US)
- From the Brown School, Washington University, St. Louis; School of Social Work, University of Michigan, Ann Arbor, Mich.; Harvard South Shore Psychiatry Residency Training Program, Harvard Medical School, Brockton, Mass.; Ann Arbor VA Medical Center, Ann Arbor; Department of Psychiatry, University of Michigan Health System, Ann Arbor; Center for Organization, Leadership, and Management Research, VA Boston Healthcare System, Boston.
- Venue
- American Journal of Psychiatry
- Published
- 2012-08
- Volume
- 169
- Issue
- 8
- Pages
- 790-804
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2168474679
- Cited by
- 603
- References
- 130
- Citations by year
- 2026: 30 · 2025: 22 · 2024: 38 · 2023: 43 · 2022: 36 · 2021: 45 · 2020: 44 · 2019: 52 · 2018: 53 · 2017: 54 · 2016: 57 · 2015: 51 · 2014: 39 · 2013: 32 · 2012: 7
- FWCI
- 6.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (R01MH079994)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Health Professions › General Health Professions › Primary Care and Health Outcomes
- Keywords
- mental illness, depression, bipolar disorder, anxiety disorders, quality of life, health care costs, integrated care, primary care, behavioral health services, specialist care
- MeSH terms
- Mental Disorders, Cooperative Behavior, Delivery of Health Care, Humans, Long-Term Care, Medicine, Mental Health Services, Primary Health Care, Models, Organizational, Comparative Effectiveness Research
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