Positive mental health and wellbeing in adults with cystic fibrosis: a cross sectional study
Abstract
Objective Screening for depression and anxiety in people with cystic fibrosis (CF) is recommended but this alone can miss the opportunity to assess and promote positive mental health and wellbeing. This cross-sectional study assessed positive mental health and wellbeing, and associations with physical health and health-related quality of life (HRQoL) in adults with CF.Methods Adults (n = 147) with CF from 9 CF centres in the Republic of Ireland completed the Warwick Edinburgh Mental Well-being scale, the Hospital Anxiety and Depression Scale and the Cystic Fibrosis Questionnaire-Revised. Demographic and physical health outcome data were also collected.Results High levels of positive mental health and wellbeing were reported in this sample. There were significant associations between positive 'mental health and wellbeing' and pulmonary function, self-reported physical health and recent hospitalizations. Positive mental health was significantly associated with 11 of the 12 CFQ-R domains assessing HRQoL.Conclusion Assessing and promoting positive mental health and wellbeing may contribute to improving or maintaining physical and mental health, and HRQoL in patients with cystic fibrosis. It provides valuable clinical information to complement depression and anxiety screening and has potential to track the effectiveness of mental health promotion strategies by assessing and monitoring positive mental health and wellbeing over time. Individuals with CF may benefit from interventions that promote positive mental health and wellbeing by enhancing coping and problem-solving skills and fostering hope and optimism. Future research should focus on the development and testing of positive mental health and wellbeing promotion interventions in people with CF.
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There are significant associations between positive mental health and self-reported physical health and quality of life.
“Additionally, there are significant associations between positive mental health and self-reported physical health and quality of life (23).”
From Virtual monitoring in CF – the importance of continuous monitoring in a multi-organ chronic condition (2023) · cites this paper as [23]
Cites
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139 · see citing works
Positive psychology: An introduction.
Seligman, M. E. P., & Csikszentmihalyi, M. (2000) · American Psychologist · doi:10.1037/0003-066x.55.1.5 · Cited by 11,351 · see citing works
The Warwick-Edinburgh Mental Well-being Scale (WEMWBS): development and UK validation
Tennant, R., Hiller, L., Fishwick, R., Platt, S., Joseph, S., Weich, S., Parkinson, J., Secker, J., & Stewart-Brown, S. (2007) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-5-63 · Cited by 5,031 · see citing works
Mental Health: New Understanding, New Hope
Brundtland, G. H. (2001) · JAMA · doi:10.1001/jama.286.19.2391 · Cited by 1,606 · see citing works
Chida, Y., & Steptoe, A. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31818105ba · Cited by 1,592 · see citing works
Cystic fibrosis genetics: from molecular understanding to clinical application
Cutting, G. R. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3849 · Cited by 969 · see citing works
Mental illness and well-being: the central importance of positive psychology and recovery approaches
Slade, M. (2010) · BMC Health Services Research · doi:10.1186/1472-6963-10-26 · Cited by 754 · see citing works
Quittner, A. L., Goldbeck, L., Abbott, J., Duff, A., Lambrecht, P., Solé, A., Tibosch, M. M., Bergsten Brucefors, A., Yüksel, H., Catastini, P., et al. (2014) · Thorax · doi:10.1136/thoraxjnl-2014-205983 · Cited by 524 · see citing works
Development and Validation of the Cystic Fibrosis Questionnaire in the United States
Quittner, A. L., Buu, A., Messer, M. A., Modi, A. C., & Watrous, M. L. (2005) · CHEST Journal · doi:10.1378/chest.128.4.2347 · Cited by 510 · see citing works
High treatment burden in adults with cystic fibrosis: challenges to disease self-management
Sawicki, G. S., Sellers, D. E., & Robinson, W. M. (2009) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2008.09.007 · Cited by 498 · see citing works
Clarke, A., Friede, T., Putz, R., Ashdown, J., Martin, S., Blake, A., Adi, Y., Parkinson, J., Flynn, P., Platt, S., et al. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-487 · Cited by 493 · see citing works
Quittner, A. L., Abbott, J., Georgiopoulos, A. M., Goldbeck, L., Smith, B., Hempstead, S. E., Marshall, B., Sabadosa, K. A., & Elborn, S. (2016) · Thorax · doi:10.1136/thoraxjnl-2015-207488 · Cited by 450 · see citing works
Well–being and affective style: neural substrates and biobehavioural correlates
Davidson, R. J. (2004) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2004.1510 · Cited by 446 · see citing works
A systematic review of online youth mental health promotion and prevention interventions
Clarke, A. M., Kuosmanen, T., & Barry, M. M. (2015) · Journal of Youth and Adolescence · doi:10.1007/s10964-014-0165-0 · Cited by 381 · see citing works
Stewart-Brown, S., Platt, S., Tennant, A., Maheswaran, H., Parkinson, J., Weich, S., Tennant, R., Taggart, F., & Clarke, A. (2011) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2011.143586.86 · Cited by 291 · see citing works
Aspinwall, L. G., & Tedeschi, R. G. (2010) · Annals of Behavioral Medicine · doi:10.1007/s12160-009-9153-0 · Cited by 271 · see citing works
Resilience in chronic diseases: A systematic review
Cal, S. F., de Sá, L. R., Glustak, M. E., & Santiago, M. B. (2015) · Cogent Psychology · doi:10.1080/23311908.2015.1024928 · Cited by 170 · see citing works
Trousselard, M., Steiler, D., Dutheil, F., Claverie, D., Canini, F., Fenouillet, F., Naughton, G., Stewart-Brown, S., & Franck, N. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.08.050 · Cited by 152 · see citing works
The relationship of children’s hope to pediatric asthma treatment adherence
Berg, C. J., Rapoff, M. A., Snyder, C. R., & Belmont, J. M. (2007) · The Journal of Positive Psychology · doi:10.1080/17439760701409629 · Cited by 145 · see citing works
Lloyd, K., & Devine, P. (2012) · Journal of Mental Health · doi:10.3109/09638237.2012.670883 · Cited by 122 · see citing works
Frisch, M. B. (2013) · Social Indicators Research · doi:10.1007/s11205-012-0140-7 · Cited by 114 · see citing works
Children's Experiences of Cystic Fibrosis: A Systematic Review of Qualitative Studies
Jamieson, N., Fitzgerald, D. A., Singh‐Grewal, D., Hanson, C. S., Craig, J. C., & Tong, A. (2014) · PEDIATRICS · doi:10.1542/peds.2014-0009 · Cited by 114 · see citing works
Gómez, M. A. L., Gabilondo, A., Codony, M., Forero, C. G., Vilagut, G., Castellví, P., Ferrer, M., & Alonso, J. (2012) · Quality of Life Research · doi:10.1007/s11136-012-0238-z · Cited by 107 · see citing works
Managing treatment complexity in cystic fibrosis: Challenges and Opportunities
Sawicki, G. S., & Tiddens, H. A. W. M. (2012) · Pediatric Pulmonology · doi:10.1002/ppul.22546 · Cited by 104 · see citing works
The psychological burden of cystic fibrosis
Quittner, A. L., Saez-Flores, E., & Barton, J. D. (2016) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000244 · Cited by 102 · see citing works
Vaingankar, J. A., Abdin, E., Chong, S. A., Sambasivam, R., Seow, E., Jeyagurunathan, A., Picco, L., Stewart-Brown, S. L., & Subramaniam, M. (2017) · Health and Quality of Life Outcomes · doi:10.1186/s12955-017-0728-3 · Cited by 96 · see citing works
Psychological and family functioning and quality of life in adolescents with cystic fibrosis
Szyndler, J., Towns, S. J., van Asperen, P. P., & McKay, K. (2005) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2005.02.004 · Cited by 95 · see citing works
Ways of coping with cystic fibrosis: implications for treatment adherence
Dodd, M. E. (2001) · Disability and Rehabilitation · doi:10.1080/09638280010004171 · Cited by 93 · see citing works
Smith, O. R. F., Alves, D. E., Knapstad, M., Haug, E., & Aarø, L. E. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1343-x · Cited by 93 · see citing works
Quittner, A. L., Sawicki, G. S., McMullen, A. H., Rasouliyan, L., Pasta, D. J., Yegin, A., & Konstan, M. W. (2012) · Quality of Life Research · doi:10.1007/s11136-011-0091-5 · Cited by 85 · see citing works
Optimism, mental health, and quality of life: A study among breast cancer patients
Colby, D. A., & Shifren, K. (2012) · Psychology Health & Medicine · doi:10.1080/13548506.2012.686619 · Cited by 69 · see citing works
Scotet, V., Dugueperoux, I., Saliou, P., Rault, G., Roussey, M., Audrézet, M., & Férec, C. (2012) · Orphanet Journal of Rare Diseases · doi:10.1186/1750-1172-7-14 · Cited by 63 · see citing works
Abbott, J., Elborn, J. S., Georgiopoulos, A. M., Goldbeck, L., Marshall, B. C., Sabadosa, K. A., Smith, B. A., & Quittner, A. L. (2015) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2014.12.015 · Cited by 56 · see citing works
Harutyunyan, M., Huang, Y., Mun, K., Yang, F., Arora, K., & Naren, A. P. (2018) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00465.2017 · Cited by 56 · see citing works
Abbott, J. (2003) · PubMed · Cited by 54 · see citing works
Duff, A. J. A., Abbott, J., Cowperthwaite, C., Sumner, C., Hurley, M. A., & Quittner, A. L. (2014) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2014.02.010 · Cited by 51 · see citing works
Almeida, L., Kashdan, T. B., Nunes, T., Coelho, R. C., Albino‐Teixeira, A., & Soares-da-Silva, P. (2008) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-008-0468-8 · Cited by 45 · see citing works
Opportunities for cystic fibrosis care teams to support treatment adherence
Riekert, K. A., Eakin, M. N., Bilderback, A. L., Ridge, A. K., & Marshall, B. C. (2014) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2014.10.003 · Cited by 45 · see citing works
Psychological resilience and intolerance of uncertainty in coping with cystic fibrosis
Mitmansgruber, H., Smrekar, U., Rabanser, B., Beck, T. N., Eder, J., & Ellemunter, H. (2015) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2015.11.011 · Cited by 39 · see citing works
Positive Mental Health and Well-Being among a Third Level Student Population
Davoren, M. P., Fitzgerald, E., Shiely, F., & Perry, I. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074921 · Cited by 38 · see citing works
Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways
Abdullah, L. H., Evans, J. R., Wang, T. T., Ford, A. A., Makhov, A. M., Nguyen, K., Coakley, R. D., Griffith, J. D., Davis, C. W., Ballard, S. T., et al. (2017) · JCI Insight · doi:10.1172/jci.insight.89752 · Cited by 37 · see citing works
Cronly, J., Duff, A. J. A., Riekert, K. A., Perry, I. J., Fitzgerald, T., Horgan, A. M., Lehane, E. A., Howe, B., Chróinín, M. N., & Savage, E. (2018) · BMJ Open · doi:10.1136/bmjopen-2017-019305 · Cited by 35 · see citing works
Orgeta, V., Sterzo, E. L., & Orrell, M. (2013) · International Psychogeriatrics · doi:10.1017/s1041610213000835 · Cited by 33 · see citing works
Recent Advances in Cystic Fibrosis
Lobo, J., Rojas-Balcazar, J., & Noone, P. G. (2012) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2012.02.006 · Cited by 23 · see citing works
Defective postsecretory maturation of MUC5B mucin in cystic fibrosis airways
Kesimer, M., Davis, C. W., Griffith, J. D., et al. (2020) · Carolina Digital Repository (University of North Carolina at Chapel Hill) · doi:10.17615/sxq1-9912 · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 46 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Collaço, N., Legg, J. P., Day, M., Culliford, D. J., Campion, A., West, C., & Darlington, A. (2021) · Pediatric Pulmonology · doi:10.1002/ppul.25537 · Cited by 27 · see citing works
Llobet, M. P., Sánchez-Ortega, M. A., Lluch‐Canut, T., Arroyo, C. M., Hidalgo-Blanco, M. Á., & Roldán-Merino, J. F. (2020) · Worldviews on Evidence-Based Nursing · doi:10.1111/wvn.12453 · Cited by 25 · see citing works
What the future holds: cystic fibrosis and aging
Blankenship, S., Landis, A. R., Williams, E. H., Lever, J. E. P., Garcia, B. A., Solomon, G. M., & Krick, S. (2024) · Frontiers in Medicine · doi:10.3389/fmed.2023.1340388 · Cited by 23 · see citing works
Social support and social isolation in adults with cystic fibrosis: An integrative review
Gulledge, A., Miller, S., & Mueller, M. (2021) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2021.110607 · Cited by 21 · see citing works
Prevention of anxiety and depression in cystic fibrosis
Havermans, T., & Willem, L. (2019) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000617 · Cited by 21 · see citing works
Kauser, S., Keyte, R., Regan, A., Nash, E. F., Fitch, G., Mantzios, M., & Egan, H. H. (2021) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-021-09831-y · Cited by 20 · see citing works
A systematic review of patient-reported outcome measures (PROMs) in cystic fibrosis
Ratnayake, I., Ahern, S., & Ruseckaite, R. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-033867 · Cited by 19 · see citing works
Gao, T., Mei, S., Li, M., D’Arcy, C., & Meng, X. (2021) · Journal of Happiness Studies · doi:10.1007/s10902-021-00384-3 · Cited by 11 · see citing works
Almweisheer, S., Bernstein, C. N., Graff, L. A., Patten, S. B., Bolton, J. M., Fisk, J. D., Hitchon, C. A., Marriott, J. J., & Marrie, R. A. (2023) · BMJ Open · doi:10.1136/bmjopen-2023-073782 · Cited by 7 · see citing works
Kauser, S., Keyte, R., Mantzios, M., & Egan, H. H. (2022) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-022-09859-8 · Cited by 7 · see citing works
Humaj-Grysztar, M., Rachel, M., Śmiech-Michalec, O., & Bonior, J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192316056 · Cited by 7 · see citing works
Psychometric properties of the Spanish version of the Protective Factors of Resilience Scale (PFRS)
Zarceño, E. L., López, M. D. C. N., & Núñez, R. M. N. (2020) · Anales de Psicología · doi:10.6018/analesps.406231 · Cited by 9 · see citing works
Preliminary Psychometric Characteristics of the Cystic Fibrosis Coping Self‐Efficacy (CF‐CSE) Scale
Friedman, D., Quittner, A. L., He, J., Chaudhary, N., Mullen, T. M. D., Bruce, A. S., Sher, Y. I., Smith, B. A., & Georgiopoulos, A. M. (2025) · Pediatric Pulmonology · doi:10.1002/ppul.71164 · Cited by 4 · see citing works
Orooji, A., Valinejadi, A., Hassanzad, M., Boloursaz, M. R., & Velayati, A. A. (2021) · Journal of Comprehensive Pediatrics · doi:10.5812/compreped.113685 · Cited by 3 · see citing works
Gulledge, A., Miller, S., Newman, S. D., Mueller, M., Christon, L., & Flume, P. A. (2023) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2023.104585 · Cited by 2 · see citing works
Greaney, C., Cichy, N., O'Sullivan, G., Sills, D., Cahalan, R., & Tierney, A. (2026) · European Respiratory Review · doi:10.1183/16000617.0238-2025 · Cited by 2 · see citing works
Vagg, T., Deasy, K. F., Chapman, W. W., Ranganathan, S. C., Plant, B. J., & Shanthikumar, S. (2023) · Frontiers in Digital Health · doi:10.3389/fdgth.2023.1196442 · Cited by 1 · see citing works
Hoffman, S., Rueda, H. A., & Chase, S. (2020) · Global Journal of Health Science · doi:10.5539/gjhs.v12n3p1 · Cited by 1 · see citing works
Qualidade de vida em pacientes com fibrose cística
Duarte, M. C., Neto, J. A. C., Felipe, M. F. B., Elias, C. M. M., Dias, A. M. C., Mendes, P. D. F. B., & Ferreira, R. E. (2022) · HU Revista · doi:10.34019/1982-8047.2021.v47.35344 · Cited by 1 · see citing works
Batool, U., & Siddiqui, D. A. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3641604 · Cited by 2 · see citing works
Adults with cystic fibrosis : mental health and patient experiences of the CF treatment
Eriksson, L. B. (2019) · Figshare
Dosedlová, J. (2019) · SWS International Scientific Conference on Social Sciences · doi:10.5593/sws.iscss.2019.3/s11.038
Kauser, S., Mantzios, M., Keyte, R., & Egan, H. H. (2025) · Chronic Illness · doi:10.1177/17423953251403206
- Authors
- Cronly, J., Duff, A., Riekert, K., Horgan, A., Lehane, E., Perry, I., Fitzgerald, A., Howe, B., Chroinin, M. N., & Savage, E.
- Affiliations
- University College Cork (IE)
- Leeds Teaching Hospitals NHS Trust (GB)
- Johns Hopkins University (US)
- Corresponding author
- Savage, Eileen
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 116
- Pages
- 125-130
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2903405696
- Cited by
- 24
- References
- 46
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 5 · 2020: 6 · 2019: 3
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Cystic Fibrosis Ireland
- Health Research Board (MRCG/2011/9)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
- Social Sciences › Psychology › Social Psychology › Psychological Well-being and Life Satisfaction
- Social Sciences › Psychology › Applied Psychology › Optimism, Hope, and Well-being
- Keywords
- cystic fibrosis, positive mental health, well-being, health-related quality of life, lung function, hospitalization, depression screening, anxiety screening, mental health promotion, adults with chronic illness
- MeSH terms
- Adult, Cross-Sectional Studies, Cystic Fibrosis, Female, Humans, Male, Mental Health, Middle Aged, Quality of Life, Surveys and Questionnaires, Young Adult
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