Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale – Depression subscale scores: An individual participant data meta-analysis of 73 primary studies
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Objective Two previous individual participant data meta-analyses (IPDMAs) found that different diagnostic interviews classify different proportions of people as having major depression overall or by symptom levels. We compared the odds of major depression classification across diagnostic interviews among studies that administered the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D).Methods Data accrued for an IPDMA on HADS-D diagnostic accuracy were analysed. We fit binomial generalized linear mixed models to compare odds of major depression classification for the Structured Clinical Interview for DSM (SCID), Composite International Diagnostic Interview (CIDI), and Mini International Neuropsychiatric Interview (MINI), controlling for HADS-D scores and participant characteristics with and without an interaction term between interview and HADS-D scores.Results There were 15,856 participants (1942 [12%] with major depression) from 73 studies, including 15,335 (97%) non-psychiatric medical patients, 164 (1%) partners of medical patients, and 357 (2%) healthy adults. The MINI (27 studies, 7345 participants, 1066 major depression cases) classified participants as having major depression more often than the CIDI (10 studies, 3023 participants, 269 cases) (adjusted odds ratio [aOR] = 1.70 (0.84, 3.43)) and the semi-structured SCID (36 studies, 5488 participants, 607 cases) (aOR = 1.52 (1.01, 2.30)). The odds ratio for major depression classification with the CIDI was less likely to increase as HADS-D scores increased than for the SCID (interaction aOR = 0.92 (0.88, 0.96)).Conclusion Compared to the SCID, the MINI may diagnose more participants as having major depression, and the CIDI may be less responsive to symptom severity.
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Controlling for depressive symptom levels, the MINI might classify depression more than other diagnostic interviews.
“We analysed studies that used different types of reference standards separately because we previously found that, controlling for depressive symptom levels, the MINI might classify depression more than other diagnostic interviews, and the CIDI might classify more participants with low level symptoms as having depression but fewer with high level symptoms.16 17 18”
Controlling for depressive symptom levels, the CIDI might classify more participants with low level symptoms as having depression but fewer with high level symptoms.
“We analysed studies that used different types of reference standards separately because we previously found that, controlling for depressive symptom levels, the MINI might classify depression more than other diagnostic interviews, and the CIDI might classify more participants with low level symptoms as having depression but fewer with high level symptoms.16 17 18”
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- Authors
- Wu, Y., Levis, B., Sun, Y., Krishnan, A., He, C., Riehm, K. E., Rice, D. B., Azar, M., Yan, X. W., Neupane, D., Bhandari, P. M., Imran, M., Chiovitti, M. J., Saadat, N., Boruff, J. T., Cuijpers, P., Gilbody, S., McMillan, D., Ioannidis, J. P. A., Kloda, L. A., Patten, S. B., Shrier, I., Ziegelstein, R. C., Henry, M., Ismail, Z., Loiselle, C. G., Mitchell, N. D., Tonelli, M., Al-Adawi, S., Beraldi, A., Braeken, A. P. B. M., Büel-Drabe, N., Bunevicius, A., Carter, G., Chen, C.-K., Cheung, G., Clover, K., Conroy, R. M., Cukor, D., da Rocha e Silva, C. E., Dabscheck, E., Daray, F. M., Douven, E., Downing, M. G., Feinstein, A., Ferentinos, P. P., Fischer, F. H., Flint, A. J., Fujimori, M., Gallagher, P., Gandy, M., Goebel, S., Grassi, L., Härter, M., Jenewein, J., Jetté, N., Julião, M., Kim, J.-M., Kim, S.-W., Kjærgaard, M., Köhler, S., Loosman, W. L., Löwe, B., Martin-Santos, R., Massardo, L., Matsuoka, Y., Mehnert, A., Michopoulos, I., Misery, L., Navines, R., O'Donnell, M. L., Öztürk, A., Peceliuniene, J., Pintor, L., Ponsford, J. L., Quinn, T. J., Reme, S. E., Reuter, K., Rooney, A. G., Sánchez-González, R., Schwarzbold, M. L., Senturk Cankorur, V., Shaaban, J., Sharpe, L., Sharpe, M., Simard, S., Singer, S., Stafford, L., Stone, J., Sultan, S., Teixeira, A. L., Tiringer, I., Turner, A., Walker, J., Walterfang, M., Wang, L.-J., White, J., Wong, D. K., Benedetti, A., & Thombs, B. D.
- Affiliations
- Jewish General Hospital (CA)
- Johns Hopkins University (US)
- McGill University (CA)
- Amsterdam Public Health (NL)
- University of York (GB)
- Stanford Medicine (US)
- Concordia University (CA)
- University of Calgary (CA)
- Universidade Federal do Rio de Janeiro (BR)
- University of Auckland (NZ)
- Alberta Health Services (CA)
- Royal College of Surgeons in Ireland (IE)
- Lithuanian University of Health Sciences (LT)
- Universidad de Buenos Aires (AR)
- Chang Gung University (TW)
- University of Newcastle Australia (AU)
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Maastricht University (NL)
- University of Toronto (CA)
- King's College London (GB)
- University Health Network (CA)
- National Cancer Centre Japan (JP)
- National and Kapodistrian University of Athens (GR)
- University of Ferrara (IT)
- Universität Hamburg (DE)
- Chonnam National University (KR)
- University Hospital of North Norway (NO)
- Jikei University School of Medicine (JP)
- NHS Lothian (GB)
- Ankara University (TR)
- The University of Sydney (AU)
- Université du Québec à Chicoutimi (CA)
- Royal Women's Hospital (AU)
- The Royal Melbourne Hospital (AU)
- McGill University Health Centre (CA)
- ORCID
- Wu, Yin
- Levis, Brooke
- Sun, Ying
- Krishnan, Ankur
- He, Chen
- Riehm, Kira E.
- Rice, Danielle B.
- Bhandari, Parash Mani
- Imran, Mahrukh
- Boruff, Jill T.
- Cuijpers, Pim
- Gilbody, Simon
- McMillan, Dean
- Ioannidis, John P.A.
- Kloda, Lorie A.
- Patten, Scott B.
- Shrier, Ian
- Ziegelstein, Roy C.
- Ismail, Zahinoor
- Loiselle, Carmen G.
- Tonelli, Marcello
- Carter, Gregory
- Chen, Chih-Ken
- Cheung, Gary
- Clover, Kerrie
- Conroy, Ronán M.
- Dabscheck, Eli
- Daray, Federico M.
- Douven, Elles
- Downing, Marina G.
- Feinstein, Anthony
- Ferentinos, Panagiotis P.
- Fischer, Felix H.
- Flint, Alastair J.
- Gallagher, Pamela
- Gandy, Milena
- Goebel, Simone
- Grassi, Luigi
- Härter, Martin
- Jenewein, Josef
- Jetté, Nathalie
- Julião, Miguel
- Kim, Jae-Min
- Kim, Sung-Wan
- Köhler, Sebastian
- Löwe, Bernd
- Massardo, Loreto
- Matsuoka, Yutaka
- Mehnert, Anja
- Michopoulos, Ioannis
- Misery, Laurent
- O'Donnell, Meaghan L.
- Öztürk, Ahmet
- Ponsford, Jennie L.
- Quinn, Terence J.
- Rooney, Alasdair G.
- Schwarzbold, Marcelo L.
- Sharpe, Louise
- Sharpe, Michael
- Simard, Sébastien
- Singer, Susanne
- Stafford, Lesley
- Stone, Jon
- Sultan, Serge
- Turner, Alyna
- Walker, Jane
- Walterfang, Mark
- Wang, Liang-Jen
- White, Jennifer
- Wong, Dana K.
- Benedetti, Andrea
- Thombs, Brett D.
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 129
- Pages
- 109892
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2994845737
- Cited by
- 48
- References
- 27
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 4 · 2023: 5 · 2022: 4 · 2021: 14 · 2020: 11
- FWCI
- 1.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (publishedVersion, cc-by-nc-nd)
- VU Research Portal (publishedVersion, other-oa)
- University of Southern Denmark Research Portal (University of Southern Denmark) (publishedVersion, cc-by-nc-nd)
- Constellation (Université du Québec à Chicoutimi) (submittedVersion)
- Minerva Access (University of Melbourne) (submittedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- eScholarship@McGill (McGill) (submittedVersion, cc-by-nc-nd)
- Figshare (submittedVersion, cc-by)
- Lithuanian University of Health Sciences (submittedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- CONICET Digital (CONICET) (submittedVersion, cc-by-nc-sa)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, cc-by-nc-nd)
- Research Publications (Maastricht University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- Canadian Breast Cancer Research Alliance
- Jewish General Hospital
- Ministry of Health and Welfare
- Ministry of Health, Labour and Welfare
- Alberta Health Services
- Instituto Nacional de Ciência e Tecnologia Translacional em Medicina
- McGill University Health Centre
- National Research Foundation of Korea
- Transport Accident Commission
- Medical Research Council Canada
- Universiteit Maastricht
- Universiti Sains Malaysia
- British Geriatrics Society
- Ministerio de Sanidad, Consumo y Bienestar Social (PI040418)
- Università degli Studi di Ferrara (026, 2000CVGG2\u2013026)
- Alberta Innovates
- Société Française de Dermatologie et de Pathologie Sexuellement Transmissible
- Health Foundation Limburg
- Canadian Prostate Cancer Research Initiative
- University of Auckland
- Fonds de Recherche du Québec - Santé
- University of Melbourne
- Norges Forskningsråd
- Deutsche Krebshilfe (107465)
- Canadian Institutes of Health Research (KRS-144045, PCG 155468)
- Ministry of Education, Culture, Sports, Science and Technology (9\u201331)
- Medical Research Council
- Multiple Sclerosis Society of Canada
- Hotchkiss Brain Institute
- European Commission
- Agencia de Innovación y Desarrollo de Andalucía
- American Psychological Association
- University of Sydney
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina
- Fondo Nacional de Desarrollo Científico y Tecnológico (20300701, 1110849, 16190501, 19230701)
- Bundesministerium für Bildung und Forschung (01ZZ0106, 7DZAIQTX, 01GY1150, 11-2)
- Universität Leipzig (1-57)
- Irish Cancer Society (CRP08GAL)
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais (APq-03539-13)
- National Health and Medical Research Council (1073041)
- Universität Heidelberg (175/2000)
- Instituto de Salud Carlos III (FIS-E08/00268, EO PI08/90869)
- Comisión Nacional de Investigación Científica y Tecnológica (PFB12/2007)
- Ministry of Education, Science and Technology (2009-0087344, 121/2000, A102065)
- Lietuvos Mokslo Taryba (LIG-03/2011)
- National Science Council (NSC 96-2314-B-182A-090-MY2)
- Departament d'Universitats, Recerca i Societat de la Informació (2009SGR1119)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- major depressive disorder, diagnostic interview, severe combined immunodeficiency, Composite International Diagnostic Interview, MINI, Hospital Anxiety and Depression Scale, diagnostic accuracy, symptom severity
- MeSH terms
- Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Probability, Psychiatric Status Rating Scales
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