Anxiety and depression in adult cancer patients: ESMO Clinical Practice Guideline
Open accessAbstract
•Anxiety and depressive disorders are common in patients with cancer.•A higher prevalence seen in patients with cancer than the general population is often underrecognised.•Psychotherapy, cognitive behavioural therapy and mindfulness-based therapies are effective treatments.•Psychopharmacological treatments have been shown to be effective treatments of anxiety and depressive disorders.
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Uncertainty, fear of recurrence or progression, symptoms, functional disruption, and financial strain can contribute to distress, anxiety, depression, sleep disturbance, and unmet psychosocial needs.
“Uncertainty, fear of recurrence or progression, symptoms, functional disruption, and financial strain can contribute to distress, anxiety, depression, sleep disturbance, and unmet psychosocial needs”
From Mapping Technologies, Support Functions, Evaluation Outcomes, and Safety Governance Related to Conversational AI Agents for Psychological Support of Patients With Cancer: Scoping Review (2026) · cites this paper as [2]
The Incidence and prevalence > Anxiety section (page unavailable) says fear of recurrence or progression is a common unmet need and that intense fear can exacerbate anxiety, disturb sleep, and favour depression. The Risk factors sections also link physical symptoms and impaired functioning with anxiety, and lower socioeconomic status with depression. The Introduction describes uncertainty as a symptom rather than a contributor, and the passages found do not specifically establish financial strain as a cause of the listed outcomes. (LLM, conf=0.82)
Experimental — accuracy not yet measuredPsychological distress and unmet psychosocial needs are common across the cancer continuum.
“Psychological distress and unmet psychosocial needs are common across the cancer continuum.”
From Mapping Technologies, Support Functions, Evaluation Outcomes, and Safety Governance Related to Conversational AI Agents for Psychological Support of Patients With Cancer: Scoping Review (2026) · cites this paper as [2]
The Introduction says anxiety and depression are the most common psychological symptoms in patients with cancer, irrespective of disease stage or treatment phase. The Incidence and prevalence > Anxiety section identifies fear of recurrence as a common unmet need of cancer survivors, but does not establish that unmet psychosocial needs generally are common across the entire cancer continuum. Page numbers are not available in our copy. (LLM, conf=0.85)
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“29 The psychology of the clinician Psychological challenges for oncology clinicians arising from their practice can interfere with communication.”
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“Research has shown that anxiety and depression not only seriously affect patients’ treat-ment compliance but are also closely associated with poor prognosis and decreased survival rates [8] while significantly reducing the quality of life of patients [6].”
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“The Distress Thermometer and problem list, which is commonly used in the USA [28] and Europe [29], does not appear suitable for FCR screening [30].”
Impact of chronic stress on intestinal mucosal immunity in colorectal cancer progression
Yang, S., Li, Y., Zhang, Y., & Wang, Y. (2024) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2024.10.007 · Cited by 12 · see citing works
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“There are differences in the impact of different anxiety emo - tion groups on the social function of adolescents (the combined anxiety group has a significantly higher impact on the social dimension of quality of life for cancer patients than the non anxiety group) (Grassi et al, 2023).”
Pu, J., Zhou, W., Zeng, W., & Shang, S. (2024) · Journal of Cancer Survivorship · doi:10.1007/s11764-024-01549-8 · Cited by 15 · see citing works
“Both cancer survivors and the elderly suffer high risks of anxiety and depression [3, 4], especially for younger older cancer survivors ( 80 years old) [5].”
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Ripamonti, C. I., & Chelazzi, C. (2024) · ESMO Open · doi:10.1016/j.esmoop.2024.103688 · Cited by 8 · see citing works
“Depression, which can occur at any stage of illness, including among long-term cancer survivors, 11 is estimated to affect approximately one in four patients with cancer.”
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“In fact, according to recent studies, almost 50% of cancer survivors still feel exhausted [8,9], whereas 30% to 40% suffer from mental health conditions, including depression, anxiety, and various adjustment or psychosomatic disorders [10,11], even after completing treatment.”
Reduction of death anxiety in patients with advanced cancer in short-term psychotherapy
Oberth, P., Springer, F., Lehmann‐Laue, A., & Mehnert, A. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1491734 · Cited by 8 · see citing works
“…increased psychological distress (Mehnert et al., 2018; Huda et al., 2022; Pinto et al., 2019; Shin et al., 2020), clinically relevant anxiety or depression (Grassi et al., 2023; Ghamari et al., 2023; Walker et al., 2020) or the fear of a return or spread of the disease; i.e. fear of progression.”
Anderson, D., Vlachostergios, P. J., Simpson, L., Bruce, S. S., Fitzpatrick, N., Connell, J., Christodoulis, E., & Kamposioras, K. V. (2025) · Scientific Reports · doi:10.1038/s41598-025-94538-5 · Cited by 8 · see citing works
“This cohort consisted of patients diagnosed with colorectal cancer, yet the applicability of this clinical pathway could include patients of any other cancer primary in line to what international guidelines recommend 21,24 .”
Neuropsychiatric symptoms as early indicators of brain tumors
Moroșan, G. C., Moroșan, A. C., & Ionescu, C. (2024) · Archive of Clinical Cases · doi:10.22551/2024.45.1104.10302 · Cited by 8 · see citing works
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Obispo, B., Bailleux, C., Cantos, B., Zamora, M. P., Jhawar, S. R., Varghese, J. S., Cabal‐Hierro, L., Luz, P., Berrocal-Almanza, L. C., & Xu, X. (2025) · Cancers · doi:10.3390/cancers17152506 · Cited by 7 · see citing works
“To mitigate these effects, psychological support, psychiatric care, and cognitive– behavioral therapy are crucial for improving mental health outcomes during and after BC treatment [70,71].”
Kiefer, P., Lebherz, L., Freitag, J., Schulz, H., Bleich, C., Bokemeyer, C., & Bokemeyer, F. (2025) · Scientific Reports · doi:10.1038/s41598-025-04849-w · Cited by 7 · see citing works
“It was expected that by reducing symptoms of depression and helping patients develop healthier coping mechanisms, the psycho-oncology care may have positively impacted alcohol use and fostered healthy behaviors 50,54 .”
InfluentialRelationship between spiritual well-being with anxiety and depression among cancer patients
Sadeghi, M. V., Tehrani, M. A. H., Pasha, H., Hamidia, A., Nabipour, M., Khafri, S., & Yadollahpour, M. (2025) · PLoS ONE · doi:10.1371/journal.pone.0322923 · Cited by 8 · see citing works
“…feelings such as fatigue, ner-vousness, restlessness, fear, insomnia, tachycardia, irregular and rapid breathing, sweating, headache, dizziness, difficulty in concentration and memory [7,8], depression and death anxiety are common problems in cancer patients that can affect their mental health [8].”
Luo, T. L., Zhang, S., Zhao, M., Song, H., Wang, S., & Han, J. (2025) · Psycho-Oncology · doi:10.1002/pon.70165 · Cited by 8 · see citing works
Depression, non-medical pain prescriptions, and suicidal behavior in cancer survivors
Mwobobia, J. M., White, M., Osazuwa‐Peters, O. L., Boakye, E. A., Abouelella, D. K., Barnes, J. M., Viet, C. T., Ramos, K., Corbett, C. M., & Osazuwa‐Peters, N. (2025) · Journal of Cancer Survivorship · doi:10.1007/s11764-024-01740-x · Cited by 7 · see citing works
“While a recent depression episode may be reflective of the acuity of an individual’s distress [37], the fact that any previous diagnosis of depression increases odds of suicidal behavior suggests that screening for depression should not only be routine, especially in cancer care, irrespective of…”
Goh, C. C., Gan, X., & Klainin‐Yobas, P. (2024) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2024.151796 · Cited by 12 · see citing works
Radiologists’ Communicative Role in Breast Cancer Patient Management: Beyond Diagnosis
Mariano, L., Nicosia, L., Sorce, A., Pesapane, F., Coppini, V., Grasso, R., Monzani, D., Pravettoni, G., Mauri, G., Venturini, M., et al. (2024) · Healthcare · doi:10.3390/healthcare12111145 · Cited by 10 · see citing works
“…clear, empathetic, and culturally sensitive communication strategies, comprehending patients’ emotional needs, and engaging in open dialogue, not only enhances patient satisfaction and treatment adherence, but also contributes to improved overall outcomes and reduced legal complications [2,72,73].”
BackgroundSun, X.-Y., Jiang, S., Jiao, B., Wang, P., Wang, Q., He, L.-J., Yin, C.-L., Liu, L., & Wang, S.-H. (2024) · Depression and Anxiety · doi:10.1155/2024/6512073 · Cited by 8 · see citing works
“Depression, characterized by persistent sadness, a lack of interest in activities, and a variety of emotional and physical problems, has consistently been shown to negatively impact the quality of life, treatment adherence, and even survival rates among cancer patients [3, 4].”
Clinical practice guidelines for perioperative multimodality treatment of non-small cell lung cancer
Jiao, W., Zhao, L., Mei, J., Zhong, J., Yu, Y., Bi, N., Zhang, L., Wang, L., Fu, X., Wang, J., et al. (2025) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003635 · Cited by 7 · see citing works
Eppingbroek, A., Lechner, L., Bakker, E., Nijkamp, M., de Witte, & Bolman, C. (2025) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2025.102855 · Cited by 7 · see citing works
Booker, R., Sawatzky, R. G., Sinnarajah, A., Qi, S., Link, C., Watson, L. C., & Stajduhar, K. (2025) · Current Oncology · doi:10.3390/curroncol32020062 · Cited by 7 · see citing works
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“Two-stage screening, as proposed by the ESMO [39], could help to make more targeted use of existing capacities.”
Košanski, T., & Neuberg, M. (2024) · Healthcare · doi:10.3390/healthcare12070725 · Cited by 7 · see citing works
van de Wal, D., den Hollander, D., Desar, I. M. E., Gelderblom, H. A. J., Oosten, A. W., Reyners, A. K. L., Steeghs, N., Husson, O., & van der Graaf, W. T. A. (2024) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2023.100434 · Cited by 9 · see citing works
“This year a European Society for Medical Oncology (ESMO) clinical practice guideline for anxiety and depression in adult cancer patients was published (Grassi et al., 2023).”
BackgroundChen, H.-Y., Zhang, L.-J., Liu, M.-Y., Li, Y.-W., & Rao, P.-J. (2025) · Cancer Pathogenesis and Therapy · doi:10.1016/j.cpt.2025.12.003 · Cited by 6 · see citing works
“8,9 In clinical practice, accompanying psychosomatic symptoms, such as depression, anxiety, and insomnia, will seriously affect the quality of life and even threaten the lives of cancer patients.”
Impact of Depression on Mortality in Patients with Pancreatic Cancer: A Systematic Review
Hein, M., & Bouchart, C. (2025) · Current Oncology · doi:10.3390/curroncol32090511 · Cited by 6 · see citing works
“…management, selective serotonin reuptake inhibitors (SSRIs) are generally considered the most suitable first-line option in the absence of specific comorbidities, due to their favorable efficacy-to-side-effect ratio and lower risk of interaction with oncological treatments [100–103].”
Evin, A., Huon, J., Thuaut, A. L., Jego, P., Nizet, P., Victorri‐Vigneau, C., Bourdon, M., & Palliative care team (2025) · BMC Palliative Care · doi:10.1186/s12904-025-01814-2 · Cited by 6 · see citing works
“Therefore, there is still a need to develop tools adapted to the assessment of anxiety [27].”
Vanlaer, N., Dirven, I., Neyns, B., & Rogiers, A. (2024) · Cancers · doi:10.3390/cancers16091638 · Cited by 6 · see citing works
“%) and specificity (75%), to detect clinical FCR [19,20].”
BackgroundAlqaisi, O., Tai, P., & Storme, G. (2026) · Medicina · doi:10.3390/medicina62010185 · Cited by 5 · see citing works
“…et al. developed the European Society of Medical Oncology (ESMO) clinical practice guidelines recommending cognitive behavioral therapy and mindfulness-based interventions for managing anxiety and depression in adult cancer patients, noting these conditions are common but under-recognized [40].”
Frailty and Oncology: An Increasingly Common Combination
Hernández-Aguiar, Y., Becerra-Bolaños, Á., & Rodríguez-Pérez, A. (2025) · Cancer Medicine · doi:10.1002/cam4.71499 · Cited by 5 · see citing works
“The presence of anxiety and depression can directly impact both treatment adherence and cancer prognosis [75].”
Pâslaru, A., Bounegru, I., Laurențiu, D., & Ciubara, A. (2025) · Diseases · doi:10.3390/diseases13100335 · Cited by 5
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Harerimana, A., Pillay, J., & Mchunu, G. (2025) · Medicine, Health care and Philosophy · doi:10.1007/s11019-025-10293-4 · Cited by 5 · see citing works
“The literature shows that anxiety and depression are the most frequently experienced psychological symptoms in cancer patients, regardless of the stage of the disease, the type of cancer, or the treatment phase they are undergoing (Die Trill 2013; Goerling et al. 2023; Grassi et al. 2023).”
Network analysis of core symptom changes in lung cancer survivors: a longitudinal study
Zhang, J., Zhao, X.-J., Zhang, G.-L., Wu, J., Guan, Q.-Y., Tian, Z., & Zeng, Y.-C. (2025) · Journal of cancer survivorship · doi:10.1007/s11764-025-01844-y · Cited by 5 · see citing works
Koshimoto, S., Amano, K., Mori, N., Imai, A., Sasaki, M., Miyajima, M., & Takeuchi, T. (2025) · Current Oncology · doi:10.3390/curroncol32050275 · Cited by 5
Şahin, G., Yuksel, H. C., Acar, C., Açar, P., & Sertöz, Ö. Ö. (2025) · BMC Psychology · doi:10.1186/s40359-025-02650-y · Cited by 5 · see citing works
“While not a formal psychiatric diagnosis, FoP encapsulates the fear, worry, and concern that cancer may return or worsen [33].”
Psychological Resilience in Newly Diagnosed Prostate Cancer Survivors: A Longitudinal Study.
Chien, C.-H., Liu, K.-L., Chuang, C., Wu, C.-T., Pang, S., Yu, K.-J., & Lin, P. (2025) · Cancer Nursing · doi:10.1097/ncc.0000000000001491 · Cited by 5 · see citing works
Salama, M., Elamin, A., Youssif, M., & Mattar, N. A. (2025) · Ultrastructural Pathology · doi:10.1080/01913123.2025.2454691 · Cited by 5
Yoga in Cancer Care: A Bibliometric Analysis of Systematic Reviews
Giridharan, S., Soumian, S., & Kumar, N. V. (2024) · Cureus · doi:10.7759/cureus.71829 · Cited by 3 · see citing works
Preferred labels and language to discuss low-risk lesions that may be cancer precursors: A review.
Lyons, M., Dhakal, S., Baker, C., Chaput, G., Finelli, A., Kupets, R., Hong, N. L., & Gagliardi, A. R. (2024) · Patient Education and Counseling · doi:10.1016/j.pec.2024.108321 · Cited by 5 · see citing works
Zhang, Y., Meng, Y., Shi, H.-R., Li, L., Li, J.-X., & Shao, H. (2026) · Medicine · doi:10.1097/md.0000000000047023 · Cited by 4 · see citing works
“[49,50] These perceptions can translate into psychological stress, leading to the onset of emotional disorders.”
Liu, X., Yang, M., & Ma, Y. (2025) · International Journal of Nursing Studies Advances · doi:10.1016/j.ijnsa.2025.100462 · Cited by 4 · see citing works
Salabat, D., Toutounchian, S., Salabat, D., Babaei, A., Malekshahi, M., Barkhordar, M., & Salehi, Z. (2025) · BMC Cancer · doi:10.1186/s12885-025-15161-1 · Cited by 4 · see citing works
Leung, C. K., Yu, A. P., Bernal, J. D. K., Recchia, F., Fong, D., Wong, S. H., Chan, D. K. C., Capio, C. M., Yu, C. C.-W., Wong, S. W. S., et al. (2025) · British Journal of Sports Medicine · doi:10.1136/bjsports-2025-110371 · Cited by 4 · see citing works
Proportion and Correlates of Psychiatric Morbidity Among Psychiatry-Assessed Oncology Inpatients
Pâslaru, A., Bounegru, I., Pleșea-Condratovici, C., Marius, M., & Ciubara, A. (2025) · Diseases · doi:10.3390/diseases13110350 · Cited by 4 · see citing works
“A recent global review likewise cites ~39% 12-month prevalence of mental disorders among patients with cancer, further situating our inpatient cohort toward the upper end of expectations [2,4,31].”
InfluentialLi, X., Li, Q.-S., Jin, S.-H., Chen, X., Shen, J., Ma, H., & Zhou, J.-G. (2025) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359251371826 · Cited by 4 · see citing works
Depression and Cancer Pain: Mediating Roles of Anxiety and Pain Beliefs.
Shim, E.-J., Ha, H., Yeom, C.-W., Son, K.-L., Kim, W.-H., & Hahm, B. (2025) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2025.07.030 · Cited by 4 · see citing works
Clothier, Z., Harris, J., Kehinde, A., Mumford, V., Upshon, K., Williamson, C., MacArthur, R., Stevenson, R., Otter, S., Teoh, M., et al. (2025) · Cancer Control · doi:10.1177/10732748251356320 · Cited by 5 · see citing works
“25,65 Although many opinions shared by patients and HCPs were congruent, there were some discrepancies in the data.”
Bokemeyer, F., Gali, K., Kiefer, P., Bleich, C., Freitag, J., Bokemeyer, C., Abel, B., Schulz, H., & Lebherz, L. (2024) · Journal of Cancer Survivorship · doi:10.1007/s11764-024-01673-5 · Cited by 4 · see citing works
Clothier, Z., Armes, J., Kehinde, A., Mumford, V., Upshon, K., Williamson, C., MacAthur, R., Stevenson, R., Otter, S., Teoh, M., et al. (2024) · Measurement and Evaluations in Cancer Care · doi:10.1016/j.ymecc.2024.100007 · Cited by 3 · see citing works
Trojnar, A., Knetki-Wróblewska, M., Sobieraj, P., & Domagała-Kulawik, J. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13051450 · Cited by 4
“A series of recommendations have been distributed in cancer settings for routine active screening for distress among patients [51].”
BackgroundKim, M., Choi, Y., Cho, Y., Kim, S., Lee, H., & Park, S. H. (2026) · Supportive Care in Cancer · doi:10.1007/s00520-026-10584-3 · Cited by 3 · see citing works
García‐Torres, F., Gómez-Solís, Á., Castillo‐Mayén, R., Espejo‐Siles, R., Jurado-González, F. J., Jabłoński, M. J., Bernabé, D. G., Jaén-Moreno, M. J., & Aranda, E. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1768998 · Cited by 2 · see citing works
“This is the case for up to 28% of patients (Grassi et al., 2023).”
InfluentialChen, X.-M., Zhang, C., He, Y.-S., Liu, Y., Xiao, K., & Sun, F. (2026) · Geriatrics & Gerontology International · doi:10.1111/ggi.70340 · Cited by 3 · see citing works
Tolstrup, L. K., Vogsen, M., Hildebrandt, M. G., Sørensen, R. W., Maguire, R., & Dieperink, K. B. (2026) · Quality of Life Research · doi:10.1007/s11136-025-04148-x · Cited by 3 · see citing works
“…review that highlighted that care for women with MBC largely focused on life-prolonging treatments and managing physical symptoms and recommended that a comprehensive, holistic approach should also encompass psychological, social, and spiritual support through inter-disciplinary support [47, 48].”
Perioperative Depressive Symptoms in Surgical Cancer Patients: a Systematic Review and Meta-analysis
O'Callaghan, E., Andrade, K., Rivera, N., Rowe, D. G., Blasingame, M., Reitz, K., Dalton, T., Crowell, K.-A., Herndon, J. E., Kaplan, S., et al. (2026) · Annals of Surgical Oncology · doi:10.1245/s10434-025-17812-w · Cited by 3 · see citing works
“4,28 Our review notes that specific timepoints in the perioperative period should be prioritized for screening, contributing additional specificity to established cancer guidelines.”
Torres, S., Trudeau, M., Liu, G., Mitsakakis, N., & Bayoumi, A. M. (2025) · Current Oncology · doi:10.3390/curroncol32110598 · Cited by 2 · see citing works
“ESAS provides a brief, practical tool to screen symptoms such anxiety and depression during oncology visits, and to identify patients in need of further evaluation and support [39,40].”
Patterns of medication use following breast cancer diagnosis: an Australian population-based study
Ng, H.-A. S., Johansen, C., Li, M., Roder, D., Beckmann, K., & Koczwara, B. (2025) · Supportive Care in Cancer · doi:10.1007/s00520-025-09732-y · Cited by 3 · see citing works
Zhang, L., Zhang, Z.-X., & Wang, F. (2025) · BMJ Open · doi:10.1136/bmjopen-2024-095926 · Cited by 3 · see citing works
Balachandran, R., Thaysen, H. V., Christensen, P., Nissen, E. R., O’Toole, M. S., Knutzen, S. M., Buskbjerg, C. R., Wu, L. M., Tauber, N. M., Amidi, A., et al. (2025) · Cancers · doi:10.3390/cancers17071127 · Cited by 4 · see citing works
“Indeed, recent guidelines published by the European Society for Medical Oncology (ESMO) recommended LE monitoring in cancer survivors [13,14], especially in patients with a high risk of recurrence and/or treatment-related side-effects [14].”
Self-citationEmpowering people affected by penile cancer: towards a model for supportive self-management
Paterson, C., Earle, W., Homewood, D. C., Chee, J., Yao, H. H., Sengupta, S., Agbejule, O. A., Knowles, R., Ee, C., Niyonsenga, T., et al. (2025) · International journal of impotence research · doi:10.1038/s41443-025-01042-5 · Cited by 3 · see citing works
Salmon, P. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009343152 · Cited by 3 · see citing works
Pecci, F., & Tarantino, P. (2024) · Translational Lung Cancer Research · doi:10.21037/tlcr-24-904 · Cited by 3
“The European Society of Medical Oncology (ESMO) developed clinical practice guidelines for anxiety and depression in adult patients with cancer encouraging a regular screening and assessment of patients for psychological distress along with timely interventions when necessary (2).”
Virtual Waiting Room: The New Narrative of Waiting in Oncology Care
Světlák, M. (2024) · Journal of Cancer Education · doi:10.1007/s13187-024-02496-9 · Cited by 2 · see citing works
Artioli, G., Deiana, L., Bertuol, M., Casella, G., Guasconi, M., Foà, C., Simone, R. D., Sarli, L., & Bonacaro, A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e31802 · Cited by 3 · see citing works
“Pervasive feelings of helplessness, disbelief, anger, high levels of stress and fighting spirit, high levels of fatalism or anxiety and minimization of the disease emerge [52,54].”
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Lin, J.-J., Zhou, R., He, Z., Wang, T.-L., Zhang, Z.-X., Zhu, Y.-J., He, Y.-H., Chang, X., Chen, Y., & ZHANG, H.-B. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1836242 · Cited by 1 · see citing works
“The National Comprehensive Cancer Network (NCCN) recommends integrating ED assessment into standard oncological care as the “ sixth vital sign ” (50, 51).”
Mental Health Screening Tools for Cancer Patients, and Their Caregivers: An Umbrella Review
Ciria-Suarez, L., Heifez, M., Martín-Parra, S., Durosini, I., Monzani, D., Coppini, V., Ferrari, M. V., Rutenkröger, M., Lange, M., Paillard-Brunet, G., et al. (2026) · Psycho-Oncology · doi:10.1002/pon.70465 · Cited by 2 · see citing works
Mind-Body Interventions for People With Cancer: Evidence, Innovation, and Implementation
Conradi, H., Petersson, J. N., Deleemans, J. M., Schuman, H. D. M., Savard, C., Irving, E., Marshall, N., & Carlson, L. E. (2026) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2026.151009 · Cited by 2 · see citing works
Lambert, S., Moore, A., Belzile, É., Rosberger, Z., Pelland, M., Hijal, T., Haggerty, J. L., Brahim, L. O., Germeil, F., Alizadeh, M., et al. (2026) · Supportive Care in Cancer · doi:10.1007/s00520-026-10383-w · Cited by 1 · see citing works
Caramore, A., O'Leary, J. M., Baser, R., Gordon, J. N., Barton-Burke, M., Fessele, K., & Majumdar, J. R. (2026) · Clinical Journal of Oncology Nursing · doi:10.1188/26.cjon.s1.e17-e23 · Cited by 2 · see citing works
Barandouzi, Z. A., Bruner, D. W., Lin, Y., Choi, H., Zeki, L. R., Akangbe, T., Epari, A., & Li, H. (2025) · Microorganisms · doi:10.3390/microorganisms14010051 · Cited by 1 · see citing works
“…pharmacological treatments (e.g., S-ketamine and Escitalopram), psychotherapeutic approaches (e.g., cognitive behavioral therapy (CBT), mindfulness-based therapies), complementary modalities (e.g., acupressure) and lifestyle interventions (e.g., dietary and exercise interventions) [7,13–17].”
Major depression and mortality from cancer: A 10-year Italian study
Grassi, L., Stivanello, E., Murri, M. B., Cruciata, M., Muscettola, A., Perlangeli, V., Pandolfi, P., Zaccagnino, B., Meggiolaro, E., Ruffilli, F., et al. (2025) · European psychiatry · doi:10.1192/j.eurpsy.2025.10048 · Cited by 2
Self-citationCardio-oncology Rehabilitation and Mental Health: Current Evidence and Future Perspectives.
Vilela, E., Viamonte, S., Prata, J., Pimentel, J. S., Joaquim, A., & Fontes-Carvalho, R. (2025) · Cardiology Clinics · doi:10.1016/j.ccl.2025.11.003 · Cited by 2 · see citing works
Analysis of anticancer drug associated adverse reactions in depressive patients from vigibase
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“Approximately one in four patients experiencing depressive symptomatology exhibit clinically significant symptoms such as insomnia, irritability or anxiety disorder 59 .”
Personalized Traditional Chinese Medicine in Oncology: Bridging the Macro State with Micro Targets.
Ji, J., Wen, Q., Yu, Y., Xiong, F., Zheng, X.-E., & Ruan, S. (2025) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x25500867 · Cited by 2 · see citing works
- Authors
- Grassi, L., Caruso, R., Riba, M. B., Lloyd-Williams, M., Kissane, D., Rodin, G., McFarland, D., Campos-Ródenas, R., Zachariae, R., Santini, D., & Ripamonti, C. I.
- Affiliations
- University of Ferrara (IT)
- University of Michigan (US)
- Monash Medical Centre (AU)
- Princess Margaret Cancer Centre (CA)
- University of Rochester Medicine (US)
- Aarhus University (DK)
- Sapienza University of Rome (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Venue
- ESMO Open
- Publisher
- Elsevier BV
- Published
- 2023-04
- Volume
- 8
- Issue
- 2
- Pages
- 101155
- ISSN
- 2059-7029 (ISSN-L)
- PMC
- PMC10163167
- OpenAlex
- W4324143593
- Cited by
- 316
- References
- 125
- Citations by year
- 2026: 128 · 2025: 106 · 2024: 76 · 2023: 6
- FWCI
- 38.54
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- ESMO Open (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion, other-oa)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, cc-by-nc-nd)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, cc-by-nc-nd)
- Liverpool John Moores University (submittedVersion)
- Zaguan (Universidad de Zaragoza) (submittedVersion, cc-by-nc-nd)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, other-oa)
- Funders
- European Society for Medical Oncology
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- anxiety, depression, cancer patients, psycho-oncology, cognitive behavioral therapy, mindfulness-based interventions, psychopharmacological treatment, prevalence of mental disorders
- MeSH terms
- Adult, Anxiety, Depression, Humans, Neoplasms
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