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Self-powered triboelectric-responsive microneedles with controllable release of optogenetically engineered extracellular vesicles for intervertebral disc degeneration repair

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Quantitative Biodistribution and Pharmacokinetics Study of GMP-Grade Exosomes Labeled with 89Zr Radioisotope in Mice and Rats

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Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy

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Insights into optimizing exosome therapies for acute skin wound healing and other tissue repair

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Mackinawite nanozymes as reactive oxygen species scavengers for acute kidney injury alleviation

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CD8 T Cell‐Derived Exosomal miR‐186‐5p Elicits Renal Inflammation via Activating Tubular TLR7/8 Signal Axis

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Injectable microenvironment-responsive hydrogels encapsulating engineered NF-κB-targeting circular RNA for osteoarthritis therapy

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Extracellular vesicles in kidney transplantation: a state-of-the-art review

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Conditioned Medium – Is it an Undervalued Lab Waste with the Potential for Osteoarthritis Management?

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Exosome-mediated delivery of super-repressor IκBα alleviates inflammation and joint damages in rheumatoid arthritis

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Nanosystems for oxidative stress regulation in the anti-inflammatory therapy of acute kidney injury

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Engineered exosomes for tissue regeneration: from biouptake, functionalization and biosafety to applications

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Macrophage Ontogeny, Phenotype, and Function in Ischemia Reperfusion-Induced Injury and Repair

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Oroxylin A ameliorates AKI-to-CKD transition through maintaining PPARα-BNIP3 signaling-mediated mitochondrial homeostasis

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Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles

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An update on renal fibrosis: from mechanisms to therapeutic strategies with a focus on extracellular vesicles

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Exploring the clinical transition of engineered exosomes designed for intracellular delivery of therapeutic proteins

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Therapeutic effects of traditional Chinese medicine on gouty nephropathy: Based on NF-κB signalingpathways

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The role of hydrogen sulfide regulation of pyroptosis in different pathological processes

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Engineered Exosomes for Drug Delivery in Cancer Therapy: A Promising Approach and Application

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Hyper-inflammatory responses in COVID-19 and anti-inflammatory therapeutic approaches

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Extracellular Vesicles as Drug Delivery Systems in Organ Transplantation: The Next Frontier

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A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, “Therapeutic advances with native and engineered human extracellular vesicles”

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Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones

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Exosomes-Mediated Signaling Pathway: A New Direction for Treatment of Organ Ischemia-Reperfusion Injury

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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain

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Safety and Anti‐Inflammatory Effects of Engineered Extracellular Vesicles (ILB‐202) for NF‐κB Inhibition: A Double‐Blind, Randomized, Placebo‐Controlled Phase 1 Trial

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Exosome-Based Delivery of Super-Repressor IκBα Alleviates Alcohol-Associated Liver Injury in Mice

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Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury

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Hypoxic regulation of extracellular vesicles: Implications for cancer therapy

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Engineered Extracellular Vesicles in Chronic Kidney Diseases: A Comprehensive Review

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Multimodal engineering of extracellular vesicles for efficient intracellular protein deliveryPreprint

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Efficacy of Allogeneic and Xenogeneic Exosomes for the Treatment of Canine Atopic Dermatitis: A Pilot Study

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Trends in Developing Extracellular Vesicle-Based Therapeutics

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Therapeutic application of extracellular vesicles for various kidney diseases: a brief review

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Bioengineering exosomes for treatment of organ ischemia-reperfusion injury

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The Effect of Super-Repressor IkB-Loaded Exosomes (Exo-srIκBs) in Chronic Post-Ischemia Pain (CPIP) Models

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Soluble thrombomodulin alleviates Diquat-induced acute kidney injury by inhibiting the HMGB1/IκBα/NF-κB signalling pathway

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Emerging Frontiers in acute kidney injury: The role of extracellular vesicles

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EXPLORing exosomes for the treatment of acute kidney injury

Goggins, E. S., & Tanaka, S. (2021) · Kidney International · doi:10.1016/j.kint.2021.05.039 · Cited by 10

Exosomes and Renal Fibrosis: Diagnostic Value, Therapeutic Potential and Challenges

Li, Y., Waheed, Y., & Sun, D. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s529311 · Cited by 10

Systems Approaches to Cell Culture-Derived Extracellular Vesicles for Acute Kidney Injury Therapy: Prospects and Challenges

Lundy, D. J., Szomolay, B., & Liao, C. (2024) · Function · doi:10.1093/function/zqae012 · Cited by 10

Advances in macrophage-derived exosomes as immunomodulators in disease progression and therapy

Chen, H., Han, Z., Ma, Y., & Meng, Q. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.113248 · Cited by 9

Extracellular vesicle-based protein and RNA delivery

Li, T., Xing, H., Huang, Y., & Lu, M. (2025) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2025.126300 · Cited by 8

Renal Ischemia–reperfusion Injury Attenuated by Exosomes Extracted From Splenic Ischemic Preconditioning Models

Liu, H., & Shen, Y. (2023) · Transplantation · doi:10.1097/tp.0000000000004514 · Cited by 8

Engineering Mesenchymal Stem Cell-Derived Extracellular Vesicles for the Treatment of Chronic Kidney Diseases

Liao, H., Shu, K.-H., Yu, W.-C., & Chiu, Y. (2025) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-025-00772-3 · Cited by 6

Engineered Nanoparticles for Theranostic Applications in Kidney Repair

Jin, C., Xue, L., Zhang, L., Yu, L., Wu, P., & Qian, H. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202402480 · Cited by 6

Extracellular Vesicles in Renal Inflammatory Diseases: Revealing Mechanisms of Extracellular Vesicle-Mediated Macrophage Regulation

Wei, J., Xie, Z., & Kuang, X. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083646 · Cited by 5

Engineered immune-driven theranostics for clinical cardiology

Zheng, J.-B., Li, X., Zhu, J., Liu, C., Song, X., Wang, B., Deng, Y. W., Feng, Y.-X., Wang, Q., Liu, J., et al. (2025) · Military Medical Research · doi:10.1186/s40779-025-00664-6 · Cited by 4

Annexin-A5 monomer as a membrane repair agent for the treatment of renal ischemia-reperfusion injury

Dong, Y., Jia, Z., Kang, B., & Zhang, W. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09606-2 · Cited by 4

Stem Cell Therapy Approaches for Ischemia: Assessing Current Innovations and Future Directions

Ma, C., Yu, A., He, T., Qian, Y., & Hu, M. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136320 · Cited by 4

Single-cell analysis of the decidua unveils the mechanism of anti-inflammatory exosomes for chorioamnionitis in nonhuman primates

Jang, S. H., Choi, H., Lee, E. M., Yoon, S., Kim, H., Park, C., Won, J., Shin, S. H., Kim, J.-S., Park, C.-W., et al. (2025) · Science Advances · doi:10.1126/sciadv.adp0467 · Cited by 3

Dual Roles of Exosomes in Tumor Progression and Their Bioengineering as Targeted Drug Carriers

Wu, J., Zhou, Y., Jiang, Y., Xu, W., Yan, T. X., & Ma, S. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c07735 · Cited by 4

Update on current and potential application of extracellular vesicles in kidney transplantation

Abinti, M., Favi, E., Alfieri, C., Zanoni, F., Armelloni, S., Ferraresso, M., Cantaluppi, V., & Castellano, G. (2023) · American Journal of Transplantation · doi:10.1016/j.ajt.2023.07.010 · Cited by 3

Shedding light on the role of extracellular vesicles in renal fibrosis

Tang, T., Zhang, Y., Crowley, S. D., Lv, L., & Liu, B. (2024) · Fundamental Research · doi:10.1016/j.fmre.2023.12.022 · Cited by 4

Progress in extracellular vesicle@STING towards immune regulation

Wang, X., Lei, I. M., Li, B., & Dai, Y. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.110990 · Cited by 4

Intermittent hypoxic training – derived exosomes in stroke rehabilitation

Ryou, M., & Burton, S. (2024) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2024.1475234 · Cited by 2

A Comprehensive Review of Engineered Bone Marrow Mesenchymal Stem Cell-Derived Exosomes as Nanotheranostic Platforms for Acute and Chronic Kidney Diseases

Convento, M. B., & Borges, F. T. (2026) · Journal of Nanotheranostics · doi:10.3390/jnt7010004 · Cited by 2

TRIM27-controlled endothelium-derived exosomes play a central role in podocyte injury in diabetic kidney disease

Tian, Y., Liu, Y., Feng, X., Wu, L., Song, W., Zhao, T., Liu, J., Miao, X., Ma, H., Jia, B., et al. (2026) · Cell Death Discovery · doi:10.1038/s41420-026-02953-y · Cited by 2

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Shi, L., Li, B., Liu, W., Wu, H., Xu, W., Ji, C., & Qian, H. (2026) · Interdisciplinary medicine · doi:10.1002/inmd.70116 · Cited by 4

Mechanisms of miRNA-mediated cell death in renal ischemia reperfusion injury

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Kluyveromyces marxianus Ameliorates High-Fat-Diet-Induced Kidney Injury by Affecting Gut Microbiota and TLR4/NF-κB Pathway in a Mouse Model

Li, N., Zhao, G., & Xu, M. (2023) · Cellular Microbiology · doi:10.1155/2023/2822094 · Cited by 2

Engineered Exosomes Carrying Super-Repressor IκB Reduced Biliary Atresia-Induced Liver Fibrosis in Minipig and Mouse Models

Kang, J., Park, C., Yun, H., Choi, C., & Seo, W. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17020264 · Cited by 1

Myeloid Cells in Acute Kidney Injury

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Biomaterial-Driven Integrated Therapy for Renal Cell Carcinoma: Renal Cancer Control and Kidney Injury Repair

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