Cited by 1,094Cannabis and Cannabinoid ResearchForensic Toxicology and Drug AnalysisHops Chemistry and Applications

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Chemical constituents of marijuana: The complex mixture of natural cannabinoids

ElSohly, Mahmoud A., Slade, Desmond·2005·Life Sciences

DOI 10.1016/j.lfs.2005.09.011

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Abstract

The cannabis plant (Cannabis sativa L.) and products thereof (such as marijuana, hashish and hash oil) have a long history of use both as a medicinal agent and intoxicant. Over the last few years there have been an active debate regarding the medicinal aspects of cannabis. Currently cannabis products are classified as Schedule I drugs under the Drug Enforcement Administration (DEA) Controlled Substances act, which means that the drug is only available for human use as an investigational drug. In addition to the social aspects of the use of the drug and its abuse potential, the issue of approving it as a medicine is further complicated by the complexity of the chemical make up of the plant. This manuscript discusses the chemical constituents of the plant with particular emphasis on the cannabinoids as the class of compounds responsible for the drug's psychological properties.

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Authors: ElSohly, M. A., & Slade, D.
Affiliations: University of Mississippi (US)
Corresponding author: ElSohly, Mahmoud A.
ORCID: ElSohly, Mahmoud A.
Slade, Desmond
Venue: Life Sciences
Publisher: Elsevier BV
Published: 2005-12
Volume: 78
Issue: 5
Pages: 539-548
ISSN: 0024-3205 (ISSN-L)
DOI: 10.1016/j.lfs.2005.09.011
OpenAlex: W2114062911
Cited by: 1,094
References: 71
Citations by year: 2026: 33 · 2025: 60 · 2024: 69 · 2023: 104 · 2022: 82 · 2021: 116 · 2020: 90 · 2019: 82 · 2018: 70 · 2017: 55 · 2016: 56 · 2015: 52 · 2014: 35 · 2013: 28 · 2012: 35
FWCI: 1.60
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Life Sciences (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Drug Abuse
Topics: Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
Life Sciences › Agricultural and Biological Sciences › Food Science › Hops Chemistry and Applications
Keywords: cannabinoids, Cannabis sativa, cannabis, hashish, chemical constituents, medical cannabis, Schedule I drug classification, psychoactive effects
MeSH terms: Cannabinoids, Cannabis, Complex Mixtures

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Chemical constituents of marijuana: The complex mixture of natural cannabinoids

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