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Radiology report generation with a learned knowledge base and multi-modal alignment
Open accessAbstract
In clinics, a radiology report is crucial for guiding a patient's treatment. However, writing radiology reports is a heavy burden for radiologists. To this end, we present an automatic, multi-modal approach for report generation from a chest x-ray. Our approach, motivated by the observation that the descriptions in radiology reports are highly correlated with specific information of the x-ray images, features two distinct modules: (i) Learned knowledge base: To absorb the knowledge embedded in the radiology reports, we build a knowledge base that can automatically distill and restore medical knowledge from textual embedding without manual labor; (ii) Multi-modal alignment: to promote the semantic alignment among reports, disease labels, and images, we explicitly utilize textual embedding to guide the learning of the visual feature space. We evaluate the performance of the proposed model using metrics from both natural language generation and clinic efficacy on the public IU-Xray and MIMIC-CXR datasets. Our ablation study shows that each module contributes to improving the quality of generated reports. Furthermore, the assistance of both modules, our approach outperforms state-of-the-art methods over almost all the metrics. Code is available at https://github.com/LX-doctorAI1/M2KT.
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“the uncategorized keyword list in CheXpert may not be transferable from one image modality to different modalities”
From Towards a holistic framework for multimodal LLM in 3D brain CT radiology report generation (2025) · cites this paper as [12]
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“the 14-feature retrieval rates cannot reflect the multi-semantic context (inclusive or exclusive; progression or resolution; relative location and size) of the disease nature over an extended clinical course.”
From Towards a holistic framework for multimodal LLM in 3D brain CT radiology report generation (2025) · cites this paper as [12]
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Seibold, C., Leichenich, T., Stein, P., Atsiatorme, E., Kliesch, P., Sevim, G. A., Trauth, P., Kremer, A., Bischoff, A., Kauczor, H.-U., et al. (2026) · European Radiology Experimental · doi:10.1186/s41747-026-00827-7
BLIX-Ray: Chest X-Ray Report Generation with Vision-Language Models and Reinforcement Learning
Akan, T., Orujpour, M., Salehpour, P., Montalvo, S. A., & Bhuiyan, M. A. N. (2026) · Journal of Imaging Informatics in Medicine · doi:10.1007/s10278-026-02317-z
TACMRN: Triple-Attention Contrastive Memory Retrieval Network for Brain CT Report Generation
He, X., Xueying, D., Zhou, Y., Bao, J., Cai, C., & Cai, S. (2026) · Journal of Imaging Informatics in Medicine · doi:10.1007/s10278-026-02436-7
ClinX ‐Net: Multimodal Visual–Language Feature Fusion for Chest X‐Ray Report Generation
Khan, M. S., Imran, A., Usman, S. M., Alshammari, A., Zheng, Y., & Hassan, B. (2026) · International Journal of Imaging Systems and Technology · doi:10.1002/ima.70469
Metadata
- Authors
- Yang, S., Wu, X., Ge, S., Zheng, Z., Zhou, S. K., & Xiao, L.
- Affiliations
- Chinese Academy of Sciences (CN)
- Tencent (China) (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- University of Science and Technology of China (CN)
- Beijing University of Posts and Telecommunications (CN)
- Corresponding author
- Xiao, Li
- Venue
- Medical Image Analysis
- Publisher
- Elsevier BV
- Published
- 2023-05
- Volume
- 86
- Pages
- 102798
- ISSN
- 1361-8415 (ISSN-L)
- OpenAlex
- W4360604432
- Cited by
- 199
- References
- 47
- Citations by year
- 2026: 58 · 2025: 89 · 2024: 41 · 2023: 11
- FWCI
- 18.03
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Medical Image Analysis (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- arXiv (Cornell University) (cc-by)
- Funders
- Tencent
- National Natural Science Foundation of China (31900979)
- Topics
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Multimodal Machine Learning Applications
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
- Keywords
- radiology report generation, chest radiography, knowledge distillation, multimodal alignment, text embeddings, semantic alignment, natural language generation
- MeSH terms
- Humans, Learning, Radiography, Radiology, Benchmarking, Knowledge Bases
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