The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
C-reactive protein levels in the early stage of COVID-19
Open accessAbstract
BACKGROUND: COVID-19 is a new infectious disease, for which there is currently no treatment. It is therefore necessary to explore biomarkers to determine the extent of lung lesions and disease severity. OBJECTIVE: We aimed to assess the usefulness of CRP levels in the early stage of COVID-19 and to correlate them with lung lesions and severe presentation. METHODS: Confirmed cases of COVID-19 were selected at the Fever Unit in two regions of Guizhou, China. On admission CRP levels were collected, and the diameter of the largest lung lesion was measured in the most severe lung lesion by lung CT scan. Differences in the diameter and CRP levels were compared in the following groups of patients: mild group, moderate group, severe group, and critical group. RESULT: CRP levels and the diameter of the largest lung lesion in the moderate group were higher than those in the mild group (Mann-Whitney test=-2.647, -2.171, P˂0.05), those in the severe group were higher than those in the moderate group (Mann-Whitney test=0.693, -2.177, P˂0.05), and those in the critical group were higher than those in the severe group (Mann-Whitney test=-0.068, -1.549, P˂0.05). The difference was statistically significant. CRP levels were positively correlated with the diameter of lung lesion and severe presentation (correlation coefficient=0.873, 0.734, P˂0.001). CONCLUSION: In the early stage of COVID-19 CRP levels were positively correlated with lung lesions and could reflect disease severity.
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Pathological findings of COVID-19 associated with acute respiratory distress syndrome
Xu, Z., Shi, L., Wang, Y., Zhang, J., Huang, L., Zhang, C., Liu, S., Zhao, P., Liu, H., Zhu, L., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30076-x · Cited by 8,545
A novel coronavirus outbreak of global health concern
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Time Course of Lung Changes at Chest CT during Recovery from Coronavirus Disease 2019 (COVID-19)
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CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV)
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Garcia-Beltran, W. F., Lam, E. C., Astudillo, M. G., Yang, D., Miller, T. E., Feldman, J., Hauser, B. M., Caradonna, T. M., Clayton, K. L., Nitido, A. D., et al. (2021) · Cell · doi:10.1016/j.cell.2020.12.015 · Cited by 722
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Kermali, M., Khalsa, R. K., Pillai, K., Ismail, Z., & Harky, A. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117788 · Cited by 687
Doglietto, F., Vezzoli, M., Gheza, F., Lussardi, G. L., Domenicucci, M., Vecchiarelli, L., Zanin, L., Saraceno, G., Signorini, L., Panciani, P. P., et al. (2020) · JAMA Surgery · doi:10.1001/jamasurg.2020.2713 · Cited by 356
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Metadata
- Authors
- Wang, L.
- Venue
- Médecine et Maladies Infectieuses
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 50
- Issue
- 4
- Pages
- 332-334
- ISSN
- 0399-077X (ISSN-L)
- OpenAlex
- W3014231150
- Cited by
- 686
- References
- 17
- FWCI
- 18.86
- Type
- journal article
- Language
- fr
- Open access
- hybrid
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