Cited by 44Reproductive tract infections researchGut microbiota and healthUrinary Tract Infections Management

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Bacterial vaginosis: A state of microbial dysbiosis

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Mondal, Arijit Sankar, Sharma, Ritu, Trivedi, Nitin·2023·Medicine in Microecology

DOI 10.1016/j.medmic.2023.100082

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Abstract

Bacterial vaginosis (BV) is a polymicrobial vaginal dysbiosis alongside lactobacillus depletion that primarily affects women of reproductive age. The fishy odor vaginal discharge is the major cause of anaerobic pathogenic bacteria colonization. Symptomatic women face specific catastrophic physiological and immunopathological consequences in addition to an elevated risk of sexually transmitted infections. Further, rash antibiotic therapy has witnessed antimicrobial-resistance amplifying vaginal infections. The emergence of biofilm-associated antimicrobial-resistance has made the issue worsened. This article has gone on to explore novel regimens, advanced diagnosis, and various cutting-edge strategies that are found to be effective in addressing these problems and restoring vaginal health.

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Authors: Mondal, A. S., Sharma, R., & Trivedi, N.
Affiliations: Guru Nanak Institute of Pharmaceutical Science and Technology (IN)
Gujarat Biotechnology University (IN)
Corresponding author: Trivedi, Nitin
ORCID: Mondal, Arijit Sankar
Sharma, Ritu
Trivedi, Nitin
Venue: Medicine in Microecology
Publisher: Elsevier BV
Published: 2023-06
Volume: 16
Pages: 100082
ISSN: 2590-0978 (ISSN-L)
DOI: 10.1016/j.medmic.2023.100082
OpenAlex: W4367319820
Cited by: 44
References: 248
Citations by year: 2026: 15 · 2025: 19 · 2024: 9 · 2023: 1
FWCI: 8.07
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Locations: Medicine in Microecology (publishedVersion, cc-by-nc-nd)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: Department of Science and Technology, Ministry of Science and Technology, India
Topics: Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Urology › Urinary Tract Infections Management
Keywords: bacterial vaginosis, vaginal dysbiosis, Lactobacillus depletion, anaerobic bacteria, sexually transmitted infections, antibiotic resistance, vaginal microbiota, treatment regimens, diagnosis

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Bacterial vaginosis: A state of microbial dysbiosis

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