The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Morphogenesis and cell cycle progression in Candida albicans
Open accessAbstract
Candida albicans, an opportunistic human pathogen, displays three modes of growth: yeast, pseudohyphae and true hyphae, all of which differ both in morphology and in aspects of cell cycle progression. In particular, in hyphal cells, polarized growth becomes uncoupled from other cell cycle events. Yeast or pseudohyphae that undergo a cell cycle delay also exhibit polarized growth, independent of cell cycle progression. The Spitzenkörper, an organelle composed of vesicles associated with hyphal tips, directs continuous hyphal elongation in filamentous fungal species and also in C. albicans hyphae. A polarisome mediates cell cycle dependent growth in yeast and pseudohyphae. Regulation of morphogenesis and cell cycle progression is dependent upon specific cyclins, all of which affect morphogenesis and some of which function specifically in yeast or hyphal cells. Future work will probably focus on the cell cycle checkpoints involved in connecting morphogenesis to cell cycle progression.
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In the citing paper
“One of the major features that distinguish true hyphae from yeast or pseudohyphae is their mode of cell cycle progression (Sudbery et al., 2004; Berman, 2006).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans (2012) · cites this paper as Berman, 2006
In the citing paper
“Cell shape in C. albicans is tightly linked to regulation of cell cycle progression, and disruption of components of the cell cycle regulatory machinery has dramatic morphological consequences (Berman, 2006; Shapiro et al., 2011).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans (2012) · cites this paper as Berman, 2006
In the citing paper
“This trimorphic fungus can grow as unicellular budding yeast and in two filamentous, multicellular forms: hyphae and pseudohyphae.”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans (2012) · cites this paper as Berman, 2006
In the citing paper
“Pseudohyphae and hyphae are distinct morphologies. Pseudohyphae resemble chains of elongated yeast cells; they are wider than hyphae and have clear constrictions at cellular junctions. Hyphae are thinner, lack a constriction between the mother and daughter cell, and have unconstricted septa.”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans (2012) · cites this paper as Berman, 2006
In the citing paper
“Elongation of C. albicans cells in response to cell cycle arrest usually represents a terminal phenotype. Although the cells continue to elongate for some time, they never divide and eventually die (Berman, 2006).”
From Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans (2012) · cites this paper as Berman, 2006
Citations
Cites
The distinct morphogenic states of Candida albicans
Sudbery, P., Gow, N., & Berman, J. (2004) · Trends in Microbiology · doi:10.1016/j.tim.2004.05.008 · Cited by 876
Self-citationSaville, S. P., Lazzell, A. L., Monteagudo, C., & Lopez-Ribot, J. L. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.5.1053-1060.2003 · Cited by 655
Fungal morphogenesis and host invasion
Gow, N. A. R., Brown, A. J. P., & Odds, F. C. (2002) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(02)00338-7 · Cited by 482
Ras Signaling Is Required for Serum-Induced Hyphal Differentiation in Candida albicans
Feng, Q., Summers, E., Guo, B., & Fink, G. R. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.20.6339-6346.1999 · Cited by 347
Zheng, X., Wang, Y.-M., & Wang, Y. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600195 · Cited by 339
Kadosh, D., & Johnson, A. D. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-01-0073 · Cited by 295
Polarisome Meets Spitzenkörper: Microscopy, Genetics, and Genomics Converge
Harris, S. D., Read, N. D., Roberson, R. W., Shaw, B. D., Seiler, S., Plamann, M., & Momany, M. (2005) · Eukaryotic Cell · doi:10.1128/ec.4.2.225-229.2005 · Cited by 280
Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae.
Kron, S. J., Styles, C. A., & Fink, G. R. (1994) · Molecular Biology of the Cell · doi:10.1091/mbc.5.9.1003 · Cited by 249
Cell cycle control of morphogenesis in budding yeast
Lew, D. J., & Reed, S. I. (1995) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(95)90048-9 · Cited by 234
Crampin, H., Finley, K. R., Gerami‐Nejad, M., Court, H., Gale, C. A., Berman, J. G., & Sudbery, P. E. (2005) · Journal of Cell Science · doi:10.1242/jcs.02414 · Cited by 195
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Growth of Candida albicans hyphae
Sudbery, P. E. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2636 · Cited by 1,110
Regulatory circuitry governing fungal development, drug resistance, and disease.
Shapiro, R. S., Robbins, N., & Cowen, L. E. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00045-10 · Cited by 576
Biswas, S., Dijck, P. V., & Datta, A. (2007) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00009-06 · Cited by 539
Morphogenesis in Candida albicans
Whiteway, M. S., & Bachewich, C. (2007) · Annual Review of Microbiology · doi:10.1146/annurev.micro.61.080706.093341 · Cited by 408
The Regulation of Filamentous Growth in Yeast
Cullen, P. J., & Sprague, G. F. (2012) · Genetics · doi:10.1534/genetics.111.127456 · Cited by 283
Metadata
- Authors
- Berman, J.
- Affiliations
- University of Minnesota (US)
- Corresponding author
- Berman, Judith
- ORCID
- Berman, Judith
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2006-12
- Volume
- 9
- Issue
- 6
- Pages
- 595-601
- ISSN
- 1369-5274 (ISSN-L)
- PMC
- PMC3552184
- OpenAlex
- W2135741099
- Cited by
- 237
- References
- 47
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 9 · 2023: 9 · 2022: 11 · 2021: 16 · 2020: 13 · 2019: 10 · 2018: 11 · 2017: 11 · 2016: 11 · 2015: 10 · 2014: 17 · 2013: 13 · 2012: 12
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Opinion in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases (R01 AI/DE 14666)
- National Institute of Dental and Craniofacial Research (R01DE014666)
- National Center for Research Resources (P41RR011823)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
- Keywords
- Candida albicans, morphogenesis, cell cycle progression, polarized growth, hyphal growth, pseudohyphae, yeast cells, Spitzenkörper, polarisome, cyclins, cell cycle checkpoints, fungal pathogens
- MeSH terms
- Candida albicans, Cell Cycle, Morphogenesis, Protein Kinases, Gene Expression Regulation, Fungal, Cell Polarity, Cell Cycle Proteins, Hyphae
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