The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Sphingolipids in host–microbial interactions
Abstract
Sphingolipids, a lipid class characterized by a long-chain amino alcohol backbone, serve vital structural and signaling roles in eukaryotes. Though eukaryotes produce sphingolipids, this capacity is phylogenetically highly restricted in Bacteria. Intriguingly, bacterial species commonly associated in high abundance with eukaryotic hosts include sphingolipid producers, such as the Bacteroidetes in the mammalian gut. To date, a role for bacterial sphingolipids in immune system maturation has been described, but their fate and impact in host physiology and metabolism remain to be elucidated. The structural conservation of bacterial sphingolipids with those produced by their mammalian hosts offer clues about which aspects of mammalian biology may be modulated by these intriguing lipids.
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Cited by
Gut microbiome lipid metabolism and its impact on host physiology
Brown, E. M., Clardy, J., & Xavier, R. J. (2023) · Cell Host & Microbe · doi:10.1016/j.chom.2023.01.009 · Cited by 447
Gut Microbiota Regulation of T Cells During Inflammation and Autoimmunity
Brown, E. M., Kenny, D. J., & Xavier, R. J. (2019) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041841 · Cited by 312
Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations
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Metadata
- Authors
- Heaver, S. L., Johnson, E. L., & Ley, R. E.
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2018-06
- Volume
- 43
- Pages
- 92-99
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2782859286
- Cited by
- 221
- References
- 9
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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