The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms
Open accessAbstract
Staphylococcus aureus is an opportunistic pathogen that normally colonizes the human anterior nares. At the same time, this pathogen is one of the leading causes of life-threatening bloodstream infections, such as sepsis and endocarditis. In this review we will present the current understanding of the pathogenesis of these invasive infections, focusing on the mechanisms of S. aureus clearance from the bloodstream by the immune system, and how this pathogen hijacks the host defense and coagulation systems and further interacts with the blood vessel endothelium. Additionally, we will delve into the regulatory mechanisms S. aureus employs during an invasive infection. These new insights into host-pathogen interactions show promising avenues for the development of novel therapies for treating bloodstream infections.
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Cites
Severe Sepsis and Septic Shock
Angus, D. C., & van der Poll, T. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1208623 · Cited by 3,961
The role of nasal carriage in Staphylococcus aureus infections
Wertheim, H. F., Melles, D. C., Vos, M. C., van Leeuwen, W., van Belkum, A., Verbrugh, H. A., & Nouwen, J. L. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)70295-4 · Cited by 2,685
Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis
Seymour, C. W., Kennedy, J. N., Wang, S., Chang, C.-C. H., Elliott, C. F., Xu, Z., Berry, S., Clermont, G., Cooper, G., Gomez, H., et al. (2019) · JAMA · doi:10.1001/jama.2019.5791 · Cited by 1,567
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Novel antibody-antibiotic conjugate eliminates intracellular S. aureus
Lehar, S. M., Pillow, T., Xu, M., Staben, L., Kajihara, K. K., Vandlen, R., DePalatis, L., Raab, H., Hazenbos, W. L., Hiroshi Morisaki, J., et al. (2015) · Nature · doi:10.1038/nature16057 · Cited by 838
Regulation of Staphylococcus aureus Virulence
Jenul, C., & Horswill, A. R. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0031-2018 · Cited by 549
Self-citationWong, C. H. Y., Jenne, C. N., Petri, B., Chrobok, N. L., & Kubes, P. (2013) · Nature Immunology · doi:10.1038/ni.2631 · Cited by 386
Kern, W. V., & Rieg, S. (2020) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2019.10.031 · Cited by 355
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Pathogenesis of Staphylococcus aureus Bloodstream Infections
Thomer, L., Schneewind, O., & Missiakas, D. (2016) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044351 · Cited by 292
Cited by
Catumbela, C. S. G., Giridharan, V. V., Barichello, T., & Morales, R. (2023) · Translational Neurodegeneration · doi:10.1186/s40035-023-00369-7 · Cited by 37
Agbasi, J. C., Ezugwu, A. L., Omeka, M. E., Ucheana, I. A., Aralu, C. C., Abugu, H. O., & Egbueri, J. C. (2024) · Journal of Environmental Science and Health, Part C · doi:10.1080/26896583.2024.2319009 · Cited by 27
Metadata
- Authors
- Kwiecinski, J. M., & Horswill, A. R.
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 53
- Pages
- 51-60
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W3011668159
- Cited by
- 373
- References
- 84
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- green
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
