Duclaux, Chamberland, Roux, Grancher, and Metchnikoff: The five musketeers of Louis Pasteur
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The Institut Pasteur was created thanks to worldwide generosity with the aim to welcome and treat rabies patients, to provide a place for scientific research and to offer new teaching programs in microbiology. Louis Pasteur invited his main collaborators, who had accompanied him during his previous investigations at École Normale Supérieure, to join him in his new institute. They contributed to the principle discoveries of Pasteur, such as the fight against spontaneous generation, the identification of the ferments of putrefaction, the fight against the silk worm disease, the research on wine and beer, and the set-up of the first vaccines against avian cholera, anthrax, swine erysipelas and rabies. There were two scientists, Émile Duclaux and Charles Chamberland, and two medical doctors, Émile Roux, and Joseph Grancher. In addition, two Russian scientists were invited to join the Institute and to head a research laboratory, Élie Metchnikoff and Nikolaï Gamaleïa, the later will finally never join the institute.
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These successes played an essential role in the creation of the Institut Pasteur, inaugurated on 14 November 1888.
“These successes played an essential role in the creation of the Institut Pasteur, inaugurated on 14 November 1888 [86].”
From Louis Pasteur: Between Myth and Reality (2022) · cites this paper as [86]
Cites
The historical milestones in the understanding of leukocyte biology initiated by Elie Metchnikoff
Cavaillon, J. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0211094 · Cited by 128 · see citing works
Self-citationCentenary of the death of Elie Metchnikoff: a visionary and an outstanding team leader
Cavaillon, J., & Legout, S. (2016) · Microbes and Infection · doi:10.1016/j.micinf.2016.05.008 · Cited by 62 · see citing works
Self-citationGelfand, T. (2002) · Bulletin of the history of medicine · doi:10.1353/bhm.2002.0176 · Cited by 24 · see citing works
Historical links between toxinology and immunology
Cavaillon, J. (2018) · Pathogens and Disease · doi:10.1093/femspd/fty019 · Cited by 19 · see citing works
Self-citationDe l’extension de la théorie des germes à l’étiologie de quelques maladies communes
Pasteur (1880) · Recueil de Médecine Vétérinaire · doi:10.3406/rmv.1880.4118 · Cited by 17 · see citing works
Cassier, M. (2008) · Science in Context · doi:10.1017/s0269889708001713 · Cited by 17 · see citing works
The Strength of a Loosely Defined Movement: Eugenics and Medicine in Imperial Russia
Krementsov, N. (2014) · Medical History · doi:10.1017/mdh.2014.68 · Cited by 13 · see citing works
The “Annales de l'Institut Pasteur”, 1887–2007: a glimpse into history
Legout, S. (2007) · Research in Microbiology · doi:10.1016/j.resmic.2007.11.005 · Cited by 9 · see citing works
Self-citationThe Institut Pasteur: 120 years of research in microbiology
Schwartz, M. (2007) · Research in Microbiology · doi:10.1016/j.resmic.2007.11.009 · Cited by 8 · see citing works
Pasteur et ses lieutenants Roux, Yersin et les autres
Milleliri, J. M. (2013) · Médecine et Santé Tropicales · doi:10.1684/mst.2013.0138 · Cited by 5 · see citing works
The fate of Rose Anna Shedlock (c1850–1878) and the early career of Émile Roux (1853–1933)
McIntyre, N. (2014) · Journal of Medical Biography · doi:10.1177/0967772013513992 · Cited by 4 · see citing works
What history tells us V. Emile Duclaux (1840–1904)
Morange, M. (2006) · Journal of Biosciences · doi:10.1007/bf02703913 · Cited by 4 · see citing works
Professeur Joseph Grancher (1843-1907) Centième anniversaire de la mort d’un pasteurien convaincu
Vayre, P. (2007) · Bulletin de l Académie Nationale de Médecine · doi:10.1016/s0001-4079(19)33057-2 · Cited by 3 · see citing works
Pasteur et ses lieutenants, Roux, Yersin et les autres
Perrot, A., & Schwartz, M. (2013) · Cited by 2 · see citing works
[The discovery of diphtheria toxic and its consequences: homage to Emile Roux].
Ramon, G. (1953) · PubMed · Cited by 2 · see citing works
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Cavaillon, J., Sansonetti, P. J., & Goldman, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02114 · Cited by 38 · see citing works
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Cavaillon, J. (2021) · The Journal of venomous animals and toxins including tropical diseases · doi:10.1590/1678-9199-jvatitd-2020-0147 · Cited by 35 · see citing works
Self-citationFrom Bacterial Poisons to Toxins: The Early Works of Pasteurians
Cavaillon, J. (2022) · Toxins · doi:10.3390/toxins14110759 · Cited by 12 · see citing works
Self-citationBrogren, C. (2024) · APMIS · doi:10.1111/apm.13325 · Cited by 10 · see citing works
Current Healthcare Systems in Light of Hyperendemic NCDs and the COVID-19 Pandemic: Time to Change
Buhmeida, A. S., Assidi, M., & Budowle, B. (2023) · Healthcare · doi:10.3390/healthcare11101382 · Cited by 6 · see citing works
Jules Bordet, un homme de conviction
Cavaillon, J., Sansonetti, P. J., & Goldman, M. (2020) · médecine/sciences · doi:10.1051/medsci/2020135 · Cited by 5 · see citing works
Self-citationHow does Elie Metchnikoff relate to the investigator of today?
Edwards, C. R., & Lipsky, P. E. (2025) · Annals of the Rheumatic Diseases · doi:10.1016/j.ard.2025.06.2134 · Cited by 2 · see citing works
Dupouy‐Camet, J. (2020) · Veterinary Parasitology · doi:10.1016/j.vetpar.2020.109175 · Cited by 1 · see citing works
Revisiting Metchnikoff's work in light of the COVID-19 pandemic
Cavaillon, J., & Levin, J. (2022) · Innate Immunity · doi:10.1177/17534259211070663 · Cited by 1 · see citing works
Self-citationMcGuire, M. E. (2023) · European Review of History Revue européenne d histoire · doi:10.1080/13507486.2023.2227210 · Cited by 1 · see citing works
Nison, M., Kotian, M., & Pai, V. (2026) · Nanomedicine and nanotoxicology · doi:10.1007/978-3-032-29006-9_1
- Authors
- Cavaillon, J.-M., & Legout, S.
- Affiliations
- Institut Pasteur (FR)
- Corresponding author
- Cavaillon, Jean-Marc
- Venue
- Microbes and Infection
- Publisher
- Elsevier BV
- Published
- 2019-06
- Volume
- 21
- Issue
- 5-6
- Pages
- 192-201
- ISSN
- 1286-4579 (ISSN-L)
- OpenAlex
- W2955167647
- Cited by
- 13
- References
- 18
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1
- FWCI
- 8.18
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Microbes and Infection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Historical Medical Research and Treatments
- Social Sciences › Arts and Humanities › History › Medical History and Innovations
- Keywords
- Louis Pasteur, Pasteur Institute, Élie Metchnikoff, history of microbiology, spontaneous generation, vaccines, rabies, anthrax, fowl cholera, swine erysipelas
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