The evidence basis for coenzyme Q therapy in oxidative phosphorylation disease

Evidence-Based Medicine

Guyatt, G. H. (1992) · JAMA · doi:10.1001/jama.1992.03490170092032 · Cited by 4,447 · see citing works

Effects of Coenzyme Q10 in Early Parkinson Disease: Evidence of Slowing of the Functional Decline

Shults, C. W. (2002) · Archives of Neurology · doi:10.1001/archneur.59.10.1541 · Cited by 984 · see citing works

Mitochondria take center stage in aging and neurodegeneration

Beal, M. F. (2005) · Annals of Neurology · doi:10.1002/ana.20624 · Cited by 957 · see citing works

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

Corral-Debrinski, M., Horton, T., Lott, M. T., Shoffner, J. M., Flint Beal, M., & Wallace, D. C. (1992) · Nature Genetics · doi:10.1038/ng1292-324 · Cited by 890 · see citing works

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain

Mecocci, P., MacGarvey, U., Kaufman, A. E., Koontz, D., Shoffner, J. M., Wallace, D. C., & Beal, M. F. (1993) · Annals of Neurology · doi:10.1002/ana.410340416 · Cited by 757 · see citing works

Mitochondrial disease

Schapira, A. H. V. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68970-8 · Cited by 594 · see citing works

Diagnostic criteria for respiratory chain disorders in adults and children

Bernier, F. P., Boneh, A., Dennett, X., Chow, C. W., Cleary, M., & Thorburn, D. R. (2002) · Neurology · doi:10.1212/01.wnl.0000033795.17156.00 · Cited by 574 · see citing works

Treatment for mitochondrial disorders

Pfeffer, G., Majamaa, K., Turnbull, D. M., Thorburn, D. R., & Chinnery, P. F. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004426.pub3 · Cited by 501 · see citing works

Minimum birth prevalence of mitochondrial respiratory chain disorders in children

Skladal, D. (2003) · Brain · doi:10.1093/brain/awg170 · Cited by 487 · see citing works

Energy metabolism defects in Huntington's disease and effects of coenzyme Q₁₀

Koroshetz, W. J., Jenkins, B. G., Rosen, B. R., & Beal, M. F. (1997) · Annals of Neurology · doi:10.1002/ana.410410206 · Cited by 405 · see citing works

Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy.

Ogasahara, S., Engel, A. G., Frens, D. B., & Mack, D. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.7.2379 · Cited by 365 · see citing works

Dichloroacetate causes toxic neuropathy in MELAS

Kaufmann, P., Engelstad, K., Wei, Y., Jhung, S., Sano, M. C., Shungu, D. C., Millar, W. S., Hong, X., Gooch, C. L., Mao, X., et al. (2006) · Neurology · doi:10.1212/01.wnl.0000196641.05913.27 · Cited by 365 · see citing works

Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease

Corral‐Debrinski, M., Shoffner, J. M., Lott, M. T., & Wallace, D. C. (1992) · Mutation Research/DNAging · doi:10.1016/0921-8734(92)90021-g · Cited by 360 · see citing works

Quinone-responsive multiple respiratory-chain dysfunction due to widespread coenzyme Q10 deficiency

Rötig, A., Appelkvist, E., Géromel, V., Chrétien, D., Kadhom, N., Edery, P., Bideau, M. L., Dallner, G., Münnich, A., Ernster, L., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02531-9 · Cited by 354 · see citing works

A randomized, placebo-controlled trial of coenzyme Q ₁₀ and remacemide in Huntington’s disease

The Huntington Study Group (2001) · Neurology · doi:10.1212/wnl.57.3.397 · Cited by 312 · see citing works

Beneficial effects of creatine, CoQ₁₀, and lipoic acid in mitochondrial disorders

Rodriguez, M. C., MacDonald, J. R., Mahoney, D. J., Parise, G., Beal, M. F., & Tarnopolsky, M. A. (2007) · Muscle & Nerve · doi:10.1002/mus.20688 · Cited by 255 · see citing works

The incidence of inherited metabolic disorders in the West Midlands, UK

Sanderson, S. C., Green, A., Preece, M. A., & Burton, H. (2006) · Archives of Disease in Childhood · doi:10.1136/adc.2005.091637 · Cited by 253 · see citing works

Familial cerebellar ataxia with muscle coenzyme Q10 deficiency

Musumeci, O., Naini, A., Slonim, A. E., Skavin, N., Hadjigeorgiou, G. L., Krawiecki, N., Weissman, B. M., Tsao, C., Mendell, J. R., Shanske, S., et al. (2001) · Neurology · doi:10.1212/wnl.56.7.849 · Cited by 252 · see citing works

Atorvastatin Decreases the Coenzyme Q10 Level in the Blood of Patients at Risk for Cardiovascular Disease and Stroke

Rundek, T., Naini, A., Sacco, R. L., Coates, K., & DiMauro, S. (2004) · Archives of Neurology · doi:10.1001/archneur.61.6.889 · Cited by 229 · see citing works

Mitochondrial DNA mutations in human degenerative diseases and aging

Wallace, D. C., Shoffner, J. M., Trounce, I. A., Brown, M. D., Ballinger, S. W., Corral‐Debrinski, M., Horton, T. M., Jun, A. S., & Lott, M. T. (1995) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(95)00021-u · Cited by 225 · see citing works

Antioxidant Treatment of Patients With Friedreich Ataxia

Hart, P. E., Lodi, R., Rajagopalan, B., Bradley, J. L., Crilley, J. G., Turner, C., Blamire, A. M., Manners, D. N., Styles, P., Schapira, A. H. V., et al. (2005) · Archives of Neurology · doi:10.1001/archneur.62.4.621 · Cited by 224 · see citing works

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

Shults, C. W., Flint Beal, M., Song, D., & Fontaine, D. (2004) · Experimental Neurology · doi:10.1016/j.expneurol.2004.05.003 · Cited by 223 · see citing works

Effects of coenzyme Q10 administration on its tissue concentrations, mitochondrial oxidant generation, and oxidative stress in the rat

Kwong, L. K., Kamzalov, S., Rebrin, I., Bayne, A.-C. V., Jana, C. K., Morris, P., Forster, M. J., & Sohal, R. S. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00916-4 · Cited by 198 · see citing works

Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: A CoQ10-responsive condition

Salviati, L., Sacconi, S., Murer, L., Zacchello, G., Franceschini, L., Laverda, A. M., Basso, G., Quinzii, C. M., Angelini, C. I., Hirano, M., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000172859.55579.a7 · Cited by 196 · see citing works

Uptake of Dietary Coenzyme Q Supplement is Limited in Rats

Zhang, Y., Åberg, F. O., Appelkvist, E., Dallner, G., & Ernster, L. (1995) · Journal of Nutrition · doi:10.1093/jn/125.3.446 · Cited by 192 · see citing works

Human Coenzyme Q10 Deficiency

Quinzii, C. M., DiMauro, S., & Hirano, M. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9190-z · Cited by 188 · see citing works

Muscle coenzyme Q10 level in statin-related myopathy

Lamperti, C., Naini, A. B., Lucchini, V., Prelle, A., Bresolin, N., Moggio, M., Sciacco, M., Kaufmann, P., & DiMauro, S. (2005) · Archives of Neurology · doi:10.1001/archneur.62.11.1709 · Cited by 178 · see citing works

Coenzyme Q deficiency and cerebellar ataxia associated with an aprataxin mutation

Quinzii, C. M., Kattah, A. G., Naini, A., Akman, H. O., Mootha, V. K., DiMauro, S., & Hirano, M. (2005) · Neurology · doi:10.1212/01.wnl.0000150588.75281.58 · Cited by 171 · see citing works

Coenzyme Q10 in cardiovascular disease

Pepe, S., Marasco, S., Haas, S. J., Sheeran, F. L., Krum, H., & Rosenfeldt, F. (2007) · Mitochondrion · doi:10.1016/j.mito.2007.02.005 · Cited by 165 · see citing works

Coenzyme Q 10 reverses pathological phenotype and reduces apoptosis in familial CoQ 10 deficiency

Giovanni, S. D., Massimiliano Mirabella, A., Spinazzola, A., Crociani, P., Silvestri, G., Broccolini, A., Tonali, P., Mauro, S. D., & Servidei, S. (2001) · Neurology · doi:10.1212/wnl.57.3.515 · Cited by 160 · see citing works

The Impact of Coenzyme Q10 on Systolic Function in Patients With Chronic Heart Failure

Sander, S. D., Coleman, C. I., Patel, A., Kluger, J., & White, C. M. (2006) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2006.03.007 · Cited by 159 · see citing works

Treatment of Kearns‐Sayre syndrome with coenzyme Q 10

Ogasahara, S., Nishikawa, Y., Yorifuji, S., Soga, F., Nakamura, Y., Takahashi, M., Hashimoto, S., Kôno, N., & Tarui, S. (1986) · Neurology · doi:10.1212/wnl.36.1.45 · Cited by 158 · see citing works

Oxidative stress in human aging and mitochondrial disease-consequences of defective mitochondrial respiration and impaired antioxidant enzyme system.

Wei, Y., Lu, C. Y., Wei, C. Y., Ma, Y. S., & Lee, H. (2001) · PubMed · Cited by 158 · see citing works

Tolerance of high‐dose (3,000 mg/day) coenzyme Q10 in ALS

Ferrante, K. L., Shefner, J., Zhang, H., Betensky, R., O'Brien, M., Yu, H., Fantasia, M., Taft, J., Beal, M. F., Traynor, B., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187070.35365.d7 · Cited by 154 · see citing works

Effects of coenzyme Q10 and α-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial α-tocopherol by coenzyme Q10

Lass, A., Forster, M. J., & Sohal, R. S. (1999) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(98)00330-x · Cited by 148 · see citing works

Distribution and breakdown of labeled coenzyme Q10 in rat

Bentinger, M., Dallner, G., Chojnacki, T., & Świeżewska, E. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01357-6 · Cited by 142 · see citing works

Rules of evidence and clinical recommendations for the management of patients.

Sackett, D. L. (1993) · PubMed · Cited by 134 · see citing works

Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue

Rosenfeldt, F., Marasco, S., Lyon, W. J., Wowk, M., Sheeran, F. L., Bailey, M., Esmore, D. S., Davis, B. B., Pick, A., Rabinov, M., et al. (2004) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2004.03.034 · Cited by 131 · see citing works

Treatment for mitochondrial disorders

Chinnery, P. F., Majamaa, K., Turnbull, D. M., & Thorburn, D. R. (2006) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004426.pub2 · Cited by 129 · see citing works

A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency

Boitier, E., Degoul, F., Desguerre, I., Charpentier, C., François, D., Ponsot, G., Diry, M., Rustin, P., & Marsac, C. (1998) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00006-9 · Cited by 127 · see citing works

Isolated Mitochondrial Myopathy Associated With Muscle Coenzyme Q10 Deficiency

Lalani, S. R., Vladutiu, G. D., Plunkett, K., Lotze, T. E., Adesina, A. M., & Scaglia, F. (2005) · Archives of Neurology · doi:10.1001/archneur.62.2.317 · Cited by 127 · see citing works

Coenzyme Q 10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease

Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A. L., Karpati, G., Andermann, F., & Arnold, D. L. (1993) · Neurology · doi:10.1212/wnl.43.5.884 · Cited by 125 · see citing works

The effects of coenzyme Q 10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation

Suzuki, S., Hinokio, Y., Ohtomo, M., Hirai, M., Hirai, A. M., Chiba, M., Kasuga, S., Sato, Y., Akai, H., & Toyota, T. (1998) · Diabetologia · doi:10.1007/s001250050950 · Cited by 116 · see citing works

Ubidecarenone in the treatment of mitochondrial myopathies: a multi-center double-blind trial

Bresolin, N., Doriguzzi, C., Ponzetto, C., Angelini, C. I., Moroni, I., Castelli, E., Cossutta, E., Binda, A., Gallanti, A., Gabellini, S., et al. (1990) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(90)90015-f · Cited by 109 · see citing works

Coenzyme Q10 Treatment in Mitochondrial Encephalomyopathies

Lang, C. J. G., Sittl, H., & Erbguth, F. (2008) · European Neurology · doi:10.1159/000117445 · Cited by 107 · see citing works

Clinical and biochemical correlations in mitochondrial myopathies treated with coenzyme Q 10

Bresolin, N., Bet, L., Binda, A., Moggio, M. G., Comi, G. P., Nador, F., Ferrante, C., Carenzi, A., & Scarlato, G. (1988) · Neurology · doi:10.1212/wnl.38.6.892 · Cited by 107 · see citing works

Mitochondrial Disease: Mutations and Mechanisms

McKenzie, M., Liolitsa, D., & Hanna, M. G. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000014829.42364.dd · Cited by 105 · see citing works

³¹ P NMR spectroscopy and ergometer exercise test as evidence for muscle oxidative performance improvement with coenzyme Q in mitochondrial myopathies

Bendahan, D., Desnuelle, C., Vanuxem, D., Confort-Gouny, S., Figarella-Branger, D., Pellissier, J. F., Kozak-Ribbens, G., Pouget, J., Serratrice, G., & Cozzone, P. J. (1992) · Neurology · doi:10.1212/wnl.42.6.1203 · Cited by 104 · see citing works

Cerebellar ataxia with coenzyme Q10 deficiency: Diagnosis and follow-up after coenzyme Q10 supplementation

Artuch, R., Brea‐Calvo, G., Briones, P., Aracil, A., Galván, M. F., Espinós, C., Corral, J., Volpini, V., Ribes, A., Andreu, A. L., et al. (2006) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2006.01.021 · Cited by 100 · see citing works

Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies

Folkers, K., & Simonsen, R. (1995) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(95)00040-b · Cited by 91 · see citing works

Coenzyme Q Intake Elevates the Mitochondrial and Tissue Levels of Coenzyme Q and α-Tocopherol in Young Mice

Kamzalov, S., Sohal, R. S., Sumien, N., & Forster, M. J. (2003) · Journal of Nutrition · doi:10.1093/jn/133.10.3175 · Cited by 89 · see citing works

Evidence-based to value-based medicine

Brown, M. M., Brown, G. C., & Sharma, S. (2005) · Medical Entomology and Zoology · Cited by 80 · see citing works

Coenzyme Q in serum and muscle of 5 patients with Kearns-Sayre syndrome and 12 patients with ophthalmoplegia plus

Zierz, S., Jahns, G., & Jerusalem, F. (1989) · Journal of Neurology · doi:10.1007/bf00314404 · Cited by 74 · see citing works

Effect of coenzyme Q10 in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS): Evaluation by noninvasive tissue oximetry

Abe, K., Matsuo, Y., Kadekawa, J., Inoue, S., & Yanagihara, T. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(98)00296-2 · Cited by 67 · see citing works

Chronic treatment of mitochondrial disease patients with dichloroacetate

Barshop, B. A., Naviaux, R. K., McGowan, K. A., Levine, F., Nyhan, W. L., Loupis-Geller, A., & Haas, R. (2004) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2004.06.009 · Cited by 67 · see citing works

Untitled work

(1997) · PubMed · Cited by 65 · see citing works

The treatment of mitochondrial myopathies and encephalomyopathies

Peterson, P. L. (1995) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(95)00039-7 · Cited by 64 · see citing works

Clinical trials of coenzyme Q10 in neurological disorders

Shults, C. W., & Haas, R. (2005) · BioFactors · doi:10.1002/biof.5520250113 · Cited by 62 · see citing works

Metabolic changes in patients with mitochondrial myopathies and effects of coenzyme Q 10 therapy

Chan, A., Reichmann, H., Kögel, A., Beck, A., & Gold, R. (1998) · Journal of Neurology · doi:10.1007/s004150050267 · Cited by 62 · see citing works

Life‐long supplementation with a low dosage of coenzyme Q10in the rat: Effects on antioxidant status and DNA damage

Quiles, J. L., Ochoa, J. J., Battino, M. A., Gutierrez-Ríos, P., Araujo-Nepomuceno, E., López‐Frías, M., Huertas, J. R., & Mataix, J. (2005) · BioFactors · doi:10.1002/biof.5520250109 · Cited by 51 · see citing works

Transport of [14C]coenzyme Q10 from the liver to other tissues after intravenous administration to guinea pigs

YUZURIHA, T., TAKADA, M., & Katayama, K. (1983) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(83)90325-2 · Cited by 43 · see citing works

Effects of mevinolin treatment on tissue dolichol and ubiquinone levels in the rat

Lőw, P., Andersson, M., Edlund, C., & Dallner, G. (1992) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(92)90081-6 · Cited by 42 · see citing works

Muscle coenzyme Q10 in mitochondrial encephalomyopathies

Matsuoka, T., Maeda, H., Goto, Y., & Nonaka, I. (1991) · Neuromuscular Disorders · doi:10.1016/0960-8966(91)90007-f · Cited by 37 · see citing works

Exercise intolerance in mitochondrial myopathy is not related to lactic acidosis

Vissing, J., Gansted, U., & Quistorff, B. (2001) · Annals of Neurology · doi:10.1002/ana.1026 · Cited by 35 · see citing works

Phosphorus Magnetic Resonance Spectroscopy in the Evaluation of Mitochondrial Myopathies: Results of a 6-Month Therapy Study with Coenzyme Q

Gold, R., Seibel, P., Reinelt, G., Schindler, R., Landwehr, P., Beck, A., & Reichmann, H. (2008) · European Neurology · doi:10.1159/000117246 · Cited by 34 · see citing works

Muscle coenzyme Q10 concentrations in patients with probable and definite diagnosis of respiratory chain disorders

Montero, R., Artuch, R., Briones, P., Nascimento, A., García‐Cazorla, À., Vilaseca, M. A., Śnchez‐Alćzar, J. A., Navas, P., Montoya, J., & Pineda, M. (2005) · BioFactors · doi:10.1002/biof.5520250112 · Cited by 33 · see citing works

Evidence-Based to Value-Based Medicine

Parker, M. J. (2006) · ACP Journal Club · doi:10.7326/acpjc-2006-144-3-a10 · Cited by 27 · see citing works

Muscle Coenzyme Q: A Potential Test for Mitochondrial Activity and Redox Status

Miles, L., Miles, M. V., Tang, P., Horn, P. S., Wong, B. L. Y., deGrauw, T. J., Morehart, P. J., & Bove, K. E. (2005) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2005.01.009 · Cited by 25 · see citing works

[Kearns-Sayre syndrome: mitochondrial encephalomyopathy caused by deficiency of the respiratory chain].

Desnuelle, C., Pellissier, J., Serratrice, G., Pouget, J., & Turnbull, D. M. (1989) · PubMed · Cited by 18 · see citing works

Coenzyme Q10 in dilated cardiomyopathy.

Manzoli, U. C., Rossi, E. M. C., Littarru, G. P., Frustaci, A., Lippa, S., ORADEI, A., & Aureli, V. (1990) · PubMed · Cited by 17 · see citing works

Plasma and tissue concentrations of coenzyme Q10 in the rat after intravenous, oral and topical administrations.

Scalori, V., Alessandri, M., Giovannini, L., & Bertelli, A. (1990) · PubMed · Cited by 12 · see citing works

Tissue Bioavailability and Detection of Coenzyme Q

Rebrin, I., Kamzalov, S., & Sohal, R. S. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)78009-x · Cited by 5 · see citing works

Oxidative stress, mitochondrial damage and neurodegenerative diseases.

Guo, C., Sun, L., Chen, X., & Zhang, D. (2013) · PubMed Central · doi:10.3969/j.issn.1673-5374.2013.21.009 · Cited by 1,308 · see citing works

Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

Sivitz, W. I., & Yorek, M. A. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.2531 · Cited by 742 · see citing works

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

Massaad, C. A., & Klann, E. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3208 · Cited by 635 · see citing works

Diagnosis and management of mitochondrial disease: a consensus statement from the mitochondrial medicine society

Parikh, S., Goldstein, A., Koenig, M. K., Scaglia, F., Enns, G. M., Saneto, R., Anselm, I., Cohen, B. H., Falk, M. J., Greene, C., et al. (2015) · Genetics in Medicine · doi:10.1038/gim.2014.177 · Cited by 607 · see citing works

The Effect of Coenzyme Q 10 on Morbidity and Mortality in Chronic Heart Failure

Mortensen, S. A., Rosenfeldt, F., Kumar, A., Dolliner, P., Filipiak, K. J., Pella, D., Alehagen, U., Steurer, G., & Littarru, G. P. (2014) · JACC: Heart Failure · doi:10.1016/j.jchf.2014.06.008 · Cited by 488 · see citing works

Mitochondrial dysfunction in neurodegenerative disorders

Klemmensen, M. M., Borrowman, S. H., Pearce, C., Pyles, B., & Chandra, B. (2024) · Neurotherapeutics · doi:10.1016/j.neurot.2023.10.002 · Cited by 396 · see citing works

The in-depth evaluation of suspected mitochondrial disease

Haas, R., Parikh, S., Falk, M. J., Saneto, R. P., Wolf, N. I., Darín, N., Wong, L.-J. C., Cohen, B. H., & Naviaux, R. K. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2007.11.018 · Cited by 363 · see citing works

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

Jin, H., Kanthasamy, A., Ghosh, A., Anantharam, V., Kalyanaraman, B., & Kanthasamy, A. G. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.09.007 · Cited by 362 · see citing works

A modern approach to the treatment of mitochondrial disease

The Mitochondrial Medicine Society, Parikh, S., Saneto, R. P., Falk, M. J., Anselm, I. A., Cohen, B. H., & Haas, R. (2009) · Current Treatment Options in Neurology · doi:10.1007/s11940-009-0046-0 · Cited by 349 · see citing works

Understanding Ubiquinone

Wang, Y., & Hekimi, S. (2016) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.12.007 · Cited by 256 · see citing works

Mitochondrial Hsp60 Chaperonopathy Causes an Autosomal-Recessive Neurodegenerative Disorder Linked to Brain Hypomyelination and Leukodystrophy

Magen, D., Georgopoulos, C. P., Bross, P., Ang, D., Segev, Y., Goldsher, D., Nemirovski, A., Shahar, E. M., Ravid, S., LUDER, A. S., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.05.016 · Cited by 212 · see citing works

Mitochondrial dysfunction in bipolar disorder: Evidence, pathophysiology and translational implications

Scaini, G., Rezin, G. T., Carvalho, A. F., STRECK, E. L., Berk, M., & Quevedo, J. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.040 · Cited by 184 · see citing works

Clinical applications of coenzyme Q₁₀

Garrido-Maraver, J. (2014) · Frontiers in Bioscience · doi:10.2741/4231 · Cited by 178 · see citing works

The mitochondrial cocktail: Rationale for combined nutraceutical therapy in mitochondrial cytopathies

Tarnopolsky, M. A. (2008) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2008.05.001 · Cited by 158 · see citing works

Coenzyme Q10 Therapy

Garrido‐Maraver, J., Cordero, M. D., Oropesa-Ávila, M., Fernández-Vega, A., de la Mata, M., Pavón, A. D., de Miguel, M., Calero, C. P., Paz, M. V., Cotán, D., et al. (2014) · Molecular Syndromology · doi:10.1159/000360101 · Cited by 154 · see citing works

Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes

Noh, Y. H., Kim, K., Shim, M. S., Choi, S.-H., Choi, S., Ellisman, M. H., Weinreb, R. N., Perkins, G. A., & Ju, W.-K. (2013) · Cell Death and Disease · doi:10.1038/cddis.2013.341 · Cited by 146 · see citing works

A randomized trial of coenzyme Q 10 in mitochondrial disorders

Glover, E. I., Martin, J. C., Maher, A. C., Thornhill, R. E., Moran, G. R., & Tarnopolsky, M. A. (2010) · Muscle & Nerve · doi:10.1002/mus.21758 · Cited by 137 · see citing works

Mitochondrial ATP synthase disorders: Molecular mechanisms and the quest for curative therapeutic approaches

Kucharczyk, R., Zick, M., Bietenhader, M., Rak, M., Couplan, E., Blondel, M., Duvezin‐Caubet, S., & di Rago, J. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.06.012 · Cited by 121 · see citing works

Coenzyme Q10: Clinical Applications beyond Cardiovascular Diseases

Testai, L., Martelli, A., Flori, L., Cicero, A. F. G., & Colletti, A. (2021) · Nutrients · doi:10.3390/nu13051697 · Cited by 82 · see citing works

Mitochondrial disease patient motivations and barriers to participate in clinical trials

Zolkipli‐Cunningham, Z., Xiao, R., Stoddart, A., McCormick, E. M., Holberts, A., Burrill, N., McCormack, S. E., Williams, L., Wang, X., Thompson, J. L. P., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0197513 · Cited by 81 · see citing works

Understanding coenzyme Q

Wang, Y., Lilienfeldt, N., & Hekimi, S. (2024) · Physiological Reviews · doi:10.1152/physrev.00040.2023 · Cited by 83 · see citing works

N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in pre-clinical models of mitochondrial complex I disease

Polyák, E., Ostrovsky, J., Peng, M., Dingley, S. D., Tsukikawa, M., Kwon, Y. J., McCormack, S. E., Bennett, M. J., Xiao, R., Seiler, C., et al. (2018) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2018.02.013 · Cited by 69 · see citing works

Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism?

Bömer, N., Pávez, M., Beverborg, N. G., Cleland, J. G. F., van Veldhuisen, D. J., & van der Meer, P. (2022) · Journal of Internal Medicine · doi:10.1111/joim.13456 · Cited by 64 · see citing works

Mitochondrial diseases and the heart: an overview of molecular basis, diagnosis, treatment and clinical course

Limongelli, G., Masarone, D., D‘Alessandro, R., & Elliot, P. M. (2011) · Future Cardiology · doi:10.2217/fca.11.79 · Cited by 65 · see citing works

CoQ10Function and Role in Heart Failure and Ischemic Heart Disease

Ayer, A., Macdonald, P. S., & Stocker, R. (2015) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071714-034258 · Cited by 64 · see citing works

Personalized Medicine in Mitochondrial Health and Disease: Molecular Basis of Therapeutic Approaches Based on Nutritional Supplements and Their Analogs

Tragni, V., Primiano, G., Tummolo, A., Beltrame, L. C., Piana, G. L., Sgobba, M. N., Cavalluzzi, M. M., Paterno, G., Gorgoglione, R., Volpicella, M., et al. (2022) · Molecules · doi:10.3390/molecules27113494 · Cited by 55 · see citing works

Clinical Characteristics of Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes

Fan, H., Lee, H.-F., Yue, C.-T., & Chi, C. (2021) · Life · doi:10.3390/life11111111 · Cited by 51 · see citing works

Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice

Falk, M. J., Polyák, E., Zhang, Z., Peng, M., King, R., Maltzman, J. S., Okwuego, E. Y., Horyn, O., Nakamaru‐Ogiso, E., Ostrovsky, J., et al. (2011) · EMBO Molecular Medicine · doi:10.1002/emmm.201100149 · Cited by 48 · see citing works

New Insights into Mitochondria in Health and Diseases

Li, Y., Zhang, H., Yu, C., Dong, X., Yang, F., Wang, M., Wen, Z., Su, M., Li, B., & Yang, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189975 · Cited by 46 · see citing works

Targeting Oxidative Stress Component in the Therapeutics of Epilepsy

Azam, F., Prasad, M. V. V., & Thangavel, N. (2012) · Current Topics in Medicinal Chemistry · doi:10.2174/156802612800229224 · Cited by 40 · see citing works

Emerging therapeutic approaches to mitochondrial diseases

Wenz, T., Williams, S. L., Bacman, S. R., & Moraes, C. T. (2010) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.109 · Cited by 40 · see citing works

Treatment of Mitochondrial Disorders

Enns, G. M. (2014) · Journal of Child Neurology · doi:10.1177/0883073814538509 · Cited by 39 · see citing works

Symptoms of somatization as a rapid screening tool for mitochondrial dysfunction in depression

Gardner, A., & Boles, R. G. (2008) · BioPsychoSocial Medicine · doi:10.1186/1751-0759-2-7 · Cited by 38 · see citing works

Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies

Mehrabani, S., Askari, G., Miraghajani, M. S., Tavakoly, R., & Arab, A. (2019) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.01.022 · Cited by 37 · see citing works

How Can We Treat Mitochondrial Encephalomyopathies? Approaches to Therapy

Horváth, R., Gorman, G. S., & Chinnery, P. F. (2008) · Neurotherapeutics · doi:10.1016/j.nurt.2008.07.002 · Cited by 36 · see citing works

Coenzyme Q10 oral bioavailability: effect of formulation type

Barakat, A., Shegokar, R., Dittgen, M., & Müller, R. H. (2013) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-013-0101-4 · Cited by 35 · see citing works

Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems

Kuszak, A. J., Espey, M. G., Falk, M. J., Holmbeck, M. A., Manfredi, G., Shadel, G. S., Vernon, H. J., & Zolkipli‐Cunningham, Z. (2017) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-020117-043644 · Cited by 33 · see citing works

Molecular diagnosis of coenzyme Q10 deficiency: an update

Yubero, D., Montero, R., Santos‐Ocaña, C., Salviati, L., Navas, P., & Artuch, R. (2018) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2018.1478290 · Cited by 29 · see citing works

Redox State of Coenzyme Q10 Determines Its Membrane Localization

Ausili, A., Torrecillas, A., Aranda, F. J., de Godos, A. M., Sánchez‐Bautista, S., Corbalán‐García, S., & Gómez-Fernández, J. C. (2008) · The Journal of Physical Chemistry B · doi:10.1021/jp802215s · Cited by 28 · see citing works

Involvement of Coenzyme Q10 in Various Neurodegenerative and Psychiatric Diseases

Ebrahimi, A., Kamyab, A., Hosseini, S., Ebrahimi, S., & Ashkani‐Esfahani, S. (2023) · Biochemistry Research International · doi:10.1155/2023/5510874 · Cited by 29 · see citing works

Design and implementation of the first randomized controlled trial of coenzyme Q10 in children with primary mitochondrial diseases

Stacpoole, P. W., deGrauw, T. J., Feigenbaum, A. S. J., Hoppel, C. L., Kerr, D. S., McCandless, S. E., Miles, M. V., Robinson, B. H., & Tang, P. (2012) · Mitochondrion · doi:10.1016/j.mito.2012.09.005 · Cited by 25 · see citing works

Why are there no proven therapies for genetic mitochondrial diseases?

Stacpoole, P. W. (2011) · Mitochondrion · doi:10.1016/j.mito.2011.05.002 · Cited by 24 · see citing works

Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway

Wojtala, A., Karkucińska‐Więckowska, A., Sardão, V. A., Szczepanowska, J., Kowalski, P., Pronicki, M., Duszyński, J., & Wieckowski, M. R. (2017) · Mitochondrion · doi:10.1016/j.mito.2017.07.002 · Cited by 23 · see citing works

Cardiomyopathy of Friedreich’s Ataxia: Use of Mouse Models to Understand Human Disease and Guide Therapeutic Development

Payne, R. M., Pride, P. M., & Babbey, C. M. (2011) · Pediatric Cardiology · doi:10.1007/s00246-011-9943-6 · Cited by 21 · see citing works

Effect of coenzyme Q10 evaluated by 1990 and 2010 ACR Diagnostic Criteria for Fibromyalgia and SCL-90-R: Four case reports and literature review

Alcocer‐Gómez, E., Cano‐García, F. J., & Cordero, M. D. (2013) · Nutrition · doi:10.1016/j.nut.2013.05.005 · Cited by 21 · see citing works

Functional Properties of Meat in Athletes’ Performance and Recovery

di Corcia, M., Tartaglia, N., Polito, R., Ambrosi, A., Messina, G., Francavilla, V. C., Cincione, R. I., della Malva, A., Ciliberti, M. G., Sevi, A., et al. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19095145 · Cited by 20 · see citing works

Royal jelly plus coenzyme Q10 supplementation improves high-intensity interval exercise performance via changes in plasmatic and salivary biomarkers of oxidative stress and muscle damage in swimmers: a randomized, double-blind, placebo-controlled pilot trial

Ovchinnikov, A. N., Paoli, A., Seleznev, V. V., & Deryugina, A. V. (2022) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2022.2086015 · Cited by 18 · see citing works

Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q10 in human cells

Yen, H., Chen, F. F., Chen, S., Huang, Y., Chen, Y., & Chen, C. (2011) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.20387 · Cited by 17 · see citing works

Therapeutical Management and Drug Safety in Mitochondrial Diseases—Update 2020

Gruosso, F., Montano, V., Simoncini, C., Siciliano, G., & Mancuso, M. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm10010094 · Cited by 16 · see citing works

The Role of Nutrient Supplementation in the Management of Chronic Pain in Fibromyalgia: A Narrative Review

Haddad, H. W., Mallepalli, N. R., Scheinuk, J. E., Bhargava, P., Cornett, E. M., Urits, I., & Kaye, A. D. (2021) · Pain and Therapy · doi:10.1007/s40122-021-00266-9 · Cited by 17 · see citing works

Coenzyme Q10 in the Treatment of Corneal Edema in Kearns-Sayre

Kim, J. T., Medsinge, A., Chauhan, B. K., Wiest, C., Scanga, H. L., Monaghan, R., Moore, W. H., & Nischal, K. K. (2016) · Cornea · doi:10.1097/ico.0000000000000927 · Cited by 16 · see citing works

Mitochondria

Cusimano, E. M., Knight, A. R., Slusser, J. G., Clancy, R. L., & Pierce, J. D. (2009) · Advanced Emergency Nursing Journal · doi:10.1097/tme.0b013e3181956200 · Cited by 15 · see citing works

TAT Opens the Door

Vyas, P. M., & Payne, R. M. (2008) · Molecular Therapy · doi:10.1038/mt.2008.24 · Cited by 15 · see citing works

Heart Transplantation for a Patient With Kearns-Sayre Syndrome and End-Stage Heart Failure

Homan, D. J., Niyazov, D. M., Fisher, P. W., Mandras, S. A., Patel, H. M., Bates, M. J., Parrino, G., & Ventura, H. O. (2011) · Congestive Heart Failure · doi:10.1111/j.1751-7133.2011.00211.x · Cited by 15 · see citing works

Mitochondrial myopathy presenting as fibromyalgia: a case report

Abdullah, M., Vishwanath, S., Elbalkhi, A., & Ambrus, J. L. (2012) · Journal of Medical Case Reports · doi:10.1186/1752-1947-6-55 · Cited by 14 · see citing works

Secondary coenzyme Q deficiency in neurological disorders

Guéguen, N., Baris, O. R., Lenaers, G., Reynier, P., & Spinazzi, M. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.01.017 · Cited by 14 · see citing works

Use of an Adaptive Study Design in Single Ascending‐Dose Pharmacokinetics of A0001 (α‐Tocopherylquinone) in Healthy Male Subjects

Hawi, A. A., Heald, S. L., & Sciascia, T. R. (2011) · The Journal of Clinical Pharmacology · doi:10.1177/0091270010390807 · Cited by 11 · see citing works

Royal Jelly Plus Coenzyme Q10 Supplementation Enhances High-Intensity Interval Exercise Performance via Alterations in Cardiac Autonomic Regulation and Blood Lactate Concentration in Runners

Ovchinnikov, A. N., Deryugina, A. V., & Paoli, A. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.893515 · Cited by 11 · see citing works

Coenzyme Q10 in salivary cells correlate with blood cells in Fibromyalgia: Improvement in clinical and biochemical parameter after oral treatment

Cordero, M. D., Santos-Garcia, R., Bermejo-Jover, D., Sánchez-Domínguez, B., Jaramillo-Santos, M. R., & Bullón, P. (2012) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2012.02.001 · Cited by 9 · see citing works

Coenzyme Q10 exhibits anti-inflammatory and immune-modulatory thereby decelerating the occurrence of experimental cerebral malaria

Nyariki, J. N., Kimani, N. M., Kibet, P. S., Kinuthia, G. K., & Isaac, A. O. (2023) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2023.111579 · Cited by 8 · see citing works

The clinical and genetic characteristics of maternally inherited diabetes and deafness ( MIDD ) with mitochondrial m. 3243A > G mutation: A 10‐year follow‐up observation study and literature review

Zheng, S., Wang, J., Sun, M., Wang, P., Shi, W., Zhang, Z., Wang, Z., & Zhang, H. (2024) · Clinical Case Reports · doi:10.1002/ccr3.8458 · Cited by 8 · see citing works

The current landscape for the treatment of mitochondrial disorders

Slone, J. D., Gui, B., & Huang, T. (2018) · Journal of genetics and genomics/Journal of Genetics and Genomics · doi:10.1016/j.jgg.2017.11.008 · Cited by 8 · see citing works

Lack of anti-inflammatory effect of coenzyme Q10 supplementation in the liver of rodents after lipopolysaccharide challenge

Neyrinck, A. M., Catry, É., Sohet, F. M., Cani, P. D., Pachikian, B. D., Bindels, L. B., & Delzenne, N. M. (2015) · Clinical Nutrition Experimental · doi:10.1016/j.yclnex.2015.07.002 · Cited by 7 · see citing works

Decoding the genetic blueprints of neurological disorders: disease mechanisms and breakthrough gene therapies

Saeed, U., Piracha, Z. Z., Tariq, M. N., Gilani, S. S., Rauf, M. A., Razaq, L., Iftikhar, M. K., Maqsood, A., & Ahsan, S. M. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1422707 · Cited by 6 · see citing works

H-FABP Levels and Psycho-Emotional Improvement of CABG Patients during Cardiac Rehabilitation

Namat, R. A., Namat, D. A., Ciocoiu, M., Hînganu, M. V., Șorodoc, L., Șorodoc, V., Foia, L. G., Florea, L., Vlad, C.-E., Tănasă, A., et al. (2022) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd9080242 · Cited by 6 · see citing works

Mitochondrial diseases

Reiner, G., & Panyard-Davis, J. L. (2012) · Nursing · doi:10.1097/01.nurse.0000413616.59485.cf · Cited by 6 · see citing works

Muscle Physiology in Healthy Men and Women and Those with Metabolic Myopathies

Devries, M. C., & Tarnopolsky, M. A. (2008) · Neurologic Clinics · doi:10.1016/j.ncl.2007.11.010 · Cited by 6 · see citing works

Metabolic myopathy presenting with polyarteritis nodosa: a case report

Vishwanath, S., Abdullah, M., Elbalkhi, A., & Ambrus, J. L. (2011) · Journal of Medical Case Reports · doi:10.1186/1752-1947-5-262 · Cited by 5 · see citing works

Investigating Fatigue and Exercise Intolerance in a University Immunology Clinic

Ambrus, J. L. (2020) · Archives of Rheumatology & Arthritis Research · doi:10.33552/arar.2020.01.000505 · Cited by 4 · see citing works

Population-based, cross-sectional assessment of dietary patterns and supplement use in mitochondrial disease

Madden, R. F., Lalonde-Bester, S., Parnell, J. A., Trudeau, M. S., Martin, J. M., Khan, A., & Shearer, J. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.06.016 · Cited by 4 · see citing works

Mitochondrial Dysfunction in Neurodegenerative Diseases

Chen, C., Zhao, Y., Wang, J., Pan, D., Wang, X., Xu, Y., Yan, J., Wang, L., Yang, X., Lu, M., et al. (2025) · MedComm · doi:10.1002/mco2.70326 · Cited by 3 · see citing works

Development and Validation by Reverse Phase High Performance Liquid Chromatography Method for the Estimation of Piperine and Coenzyme Q10 in Bulk and Pharmaceutical Dosage Form

Sarkar, M., Bag, P., Kumar, B., & Chawla, P. A. (2021) · Indian Journal of Pharmaceutical Sciences · doi:10.36468/pharmaceutical-sciences.875 · Cited by 3 · see citing works

Gulf War toxicant-induced reductions in dendritic arbors and spine densities of dentate granule cells are improved by treatment with a Nrf2 activator

Murray, K. E., Ratliff, W. A., Delic, V., & Citron, B. A. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148682 · Cited by 3 · see citing works

Increased ubiquinone concentration after intracerebroventricularly-administered ubiquinol to selected rat brain regions

Gvozdjáková, A., Mravec, B., Kucharská, J., Lackovicova, L., Ondičová, K., Tkačov, M., & Singh, R. B. (2012) · General Physiology and Biophysics · doi:10.4149/gpb_2012_052 · Cited by 3 · see citing works

Recovering Mitochondrial Function in Patients’ Fibroblasts

Wieckowski, M. R., Danese, A., Morciano, G., Pronicki, M., Duszyński, J., Pinton, P., & Karkucińska‐Więckowska, A. (2018) · Springer eBooks · doi:10.1007/978-3-319-73344-9_17 · Cited by 3 · see citing works

Muscle Physiology in Healthy Men and Women and Those with Metabolic Myopathies

Devries, M. C., & Tarnopolsky, M. A. (2008) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2008.10.011 · Cited by 2 · see citing works

Design and physicochemical characterization of spray-dried microcapsules encapsulating o/w emulsion-based drug combinations

Le, P.-Q., Kim, J. H., Park, K., & Lee, B. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.127496 · Cited by 1 · see citing works

Supporting Children With Mitochondrial Disorders

Haas, R., Hoy, L., & Berenhaut, E. (2014) · ICAN Infant Child & Adolescent Nutrition · doi:10.1177/1941406414531929 · Cited by 1 · see citing works

Mitochondrial diseases: past, present, and future

Akl, A. I., Afsah, I., & Saad, R. A. (2022) · Urology & Nephrology Open Access Journal · doi:10.15406/unoaj.2022.10.00316 · Cited by 1 · see citing works

Enfermedades mitocondriales: problemas en la planta de producción de energía

Reiner, G., & Panyard-Davis, J. L. (2012) · Nursing (Ed española) · doi:10.1016/s0212-5382(12)70114-0

KATERE SO PRILAGODITVENE REAKCIJE NA TELESNO

Eiken, O. (2008)

Potentiel thérapeutique du coenzyme Q10

Pincemail, J., & Defraigne, J.-O. (2008) · ORBi (University of Liège)

MITOCHONDRIAL CYTOPATHIES IN CHILDREN AND ADULTS

Tarnopolsky, M. A. (2009) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/01.con.0000348880.16694.08

Принципы профилактического и лечебного применения альфа-липоевой кислоты и коэнзима Q10 при коморбидных метаболических состояниях

Filippova, A. Y. (2020) · HYPERTENSION · doi:10.22141/2224-1485.13.4.2020.211956

Current World Literature

(2008) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32830fb782

Reply

Nischal, K. K., Scanga, H. L., & Kim, J. T. (2016) · Cornea · doi:10.1097/ico.0000000000001041

Clinical and genetic characteristics in maternally inherited diabetes and deafness (MIDD) with mitochondrial m.3243A>G mutation: A 10-year follow up observation study of 1 familyPreprint

Zheng, S., Wang, J., Sun, M., Wang, P., Shi, W. M., Zhang, Z., Wang, Z., & Zhang, H. (2023) · doi:10.22541/au.169459029.98052841/v1

The relationship between low levels of coenzyme Q10 and oxidative damage in patients with fibromyalgia

Dilaver, E., & Yılmaz, S. E. (2024) · Toros University Journal of Food Nutrition and Gastronomy · doi:10.58625/jfng-2671

Aiding the “Powerhouse of the Cell”: Investigating ATP Supplementation as a Potential Therapeutic Strategy in MELAS-Associated Cardiogenic Shock

Rath, D., Roberts, V., Waghmare, S., Hassan, H., Harris, M., Ramallo, M., Kuo, P., Zinabu, S., Bisrat, M., & Michael, M. B. (2025) · medtigo Journal of Medicine · doi:10.63096/medtigo3092224

Role of the prolyl isomerase Pin1 in the pathogenesis of Parkinson's disease and neuroprotection by novel targeted compounds in pre-clinical animal models of the disease

Ghosh, A. (2012) · doi:10.31274/etd-180810-1769

Relationships among Processing Speed, Attention, and Biochemical Features in Children Identified with Mitochondrial Disease

Chang, J. S. (2022) · Digital Archive @ GSU · doi:10.57709/1955407

Coenzyme Q10 in the Treatment of Mitochondrial Disease

Neergheen, V., Chalasani, A., Wainwright, L., Yubero, D., Montero, R., Artuch, R., & Hargreaves, I. P. (2017) · Journal of Inborn Errors of Metabolism and Screening · doi:10.1177/2326409817707771 · Cited by 41 · see citing works

The efficacy of coenzyme Q 10 treatment in alleviating the symptoms of primary coenzyme Q 10 deficiency: A systematic review

Wang, Y., & Hekimi, S. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17488 · Cited by 44 · see citing works

Coenzyme Q 10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease

Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A. L., Karpati, G., Andermann, F., & Arnold, D. L. (1993) · Neurology · doi:10.1212/wnl.43.5.884 · Cited by 125 · see citing works

Coenzyme Q and mitochondrial disease

Quinzii, C. M., & Hirano, M. (2010) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.108 · Cited by 185 · see citing works

Coenzyme Q10 as a therapy for mitochondrial disease

Hargreaves, I. P. (2014) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2014.01.020 · Cited by 170 · see citing works