Energy metabolism defects in Huntington's disease and effects of coenzyme Q10

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Evidence for irnnairment of energy metabofism in vivo in Huntington's disease using localized 1H NMR spectroscopy

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Factors Associated With Slow Progression in Huntington's Disease

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Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

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Coenzyme Q₁₀ and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate

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Clinical and biochemical correlations in mitochondrial myopathies treated with coenzyme Q 10

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Clinical improvement after administration of coenzyme Q10 in a patient with mitochondrial encephalomyopathy

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Increased lactate in cerebrospinal fluid from 7 siblings in a family with mitochondrial myopathy and cerebellar ataxia

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Increased alanine aminotransferase activity in the Huntington's disease putamen

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STA-MCA bypass surgery for chronic cerebral ischemia

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Metabolism and function of coenzyme Q

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Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration

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Effects of Coenzyme Q10 in Early Parkinson Disease: Evidence of Slowing of the Functional Decline

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Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

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Mitochondrial Dysfunction in Neurodegenerative Diseases

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Mitochondrial dysfunction in neurodegenerative diseases

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Coenzyme Q ₁₀ administration increases brain mitochondrial concentrations and exerts neuroprotective effects

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Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

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Neuroprotective Effects of Creatine in a Transgenic Mouse Model of Huntington's Disease

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Oxidative stress in Huntington’s disease

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Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene

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Energetics in the pathogenesis of neurodegenerative diseases

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Mechanisms of neurodegeneration in Huntington’s disease

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

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Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases

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Neuroprotective Effects of Creatine and Cyclocreatine in Animal Models of Huntington’s Disease

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Mitochondrial Diseases of the Brain

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N-Methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease

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Replicating Huntington's disease phenotype in experimental animals

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A Randomized Clinical Trial of High-Dosage Coenzyme Q10 in Early Parkinson Disease

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Neuronal degeneration and mitochondrial dysfunction

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Therapeutic Effects of Coenzyme Q₁₀and Remacemide in Transgenic Mouse Models of Huntington's Disease

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Functions and effects of creatine in the central nervous system

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3‐Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease

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Mitochondria in Neurodegeneration: Acute Ischemia and Chronic Neurodegenerative Diseases

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Creatine: Endogenous Metabolite, Dietary, and Therapeutic Supplement

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Role of Oxidative Stress and Antioxidants in Neurodegenerative Diseases

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A randomized, placebo-controlled trial of coenzyme Q ₁₀ and remacemide in Huntington’s disease

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Oxidative Damage in Huntington's Disease Pathogenesis

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Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease

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Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease

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Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases

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Mitochondrial Approaches for Neuroprotection

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HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

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Creatine Increases Survival and Delays Motor Symptoms in a Transgenic Animal Model of Huntington's Disease

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Oxidative Stress in Neurodegeneration

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Mitochondria in Huntington's disease

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Mitochondria and degenerative disorders

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Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease

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Mitochondrial Dysfunction and Oxidative Damage in Alzheimer's and Parkinson's Diseases and Coenzyme Q10 as a Potential Treatment

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Regional Specificity of Brain Atrophy in Huntington's Disease

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Transcriptional signatures in Huntington's disease

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[18F]Fluorodeoxyglucose positron emission tomography in the diagnosis of cancer in patients with paraneoplastic neurological syndrome and anti-Hu antibodies

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Antioxidants as treatment for neurodegenerative disorders

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Involvement of Mitochondrial Complex II Defects in Neuronal Death Produced by N-Terminus Fragment of Mutated Huntingtin

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Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders

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The Energetics of Huntington's Disease

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Bioenergetic approaches for neuroprotection in Parkinson's disease

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Impaired PGC-1α function in muscle in Huntington's disease

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Huntington Disease

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Effects of overexpression of Huntingtin proteins on mitochondrial integrity

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Experimental therapeutics in transgenic mouse models of Huntington's disease

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Energy deficit in Huntington disease: why it matters

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Microbiome profiling reveals gut dysbiosis in a transgenic mouse model of Huntington's disease

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Mitochondrial Dysfunction in Huntington’s Disease

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