Mitochondrial dysfunction and gut microbiota imbalance: An intriguing relationship in chronic kidney disease
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Butyrate, a type of SCFA, can increase mitochondrial inner membrane proton leakage and decrease ROS.
“butyrate, a type of SCFA, can increase mitochondrial inner membrane proton leakage and decrease ROS [78]”
From Healthy Human Fecal Microbiota Transplantation into Mice Attenuates MPTP-Induced Neurotoxicity <i>via</i> AMPK/SOD2 Pathway (2023) · cites this paper as [78]
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Food as medicine: targeting the uraemic phenotype in chronic kidney disease
Mafra, D., Borges, N. A., Lindholm, B., Shiels, P. G., Evenepoel, P., & Stenvinkel, P. (2021) · Nature Reviews Nephrology · doi:10.1038/s41581-020-00345-8 · Cited by 238 · see citing works
Self-citationXie, Z., Zhang, M., Luo, Y., Jin, D., Guo, X., Yang, W., Zheng, J., Zhang, H., Zhang, L., Deng, C., et al. (2023) · Aging and disease · doi:10.14336/ad.2023.0309 · Cited by 80 · see citing works
- Authors
- Mafra, D., Borges, N. A., Lindholm, B., & Stenvinkel, P.
- Affiliations
- Universidade Federal Fluminense (BR)
- Karolinska Institutet (SE)
- Corresponding author
- Borges, Natália Alvarenga
- Venue
- Mitochondrion
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 47
- Pages
- 206-209
- ISSN
- 1567-7249 (ISSN-L)
- OpenAlex
- W2899953213
- Cited by
- 27
- References
- 42
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 8 · 2022: 5 · 2021: 2 · 2020: 6
- FWCI
- 0.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Mitochondrion (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- mitochondrial dysfunction, gut microbiota, chronic kidney disease, intestinal epithelial cells, short-chain fatty acids, mitochondrial ultrastructure, inflammasome activation, intestinal inflammation, inflammatory bowel disease, colorectal cancer, therapeutic interventions
- MeSH terms
- Gastrointestinal Microbiome, Humans, Mitochondria, Renal Insufficiency, Chronic
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