The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
WormBase ParaSite − a comprehensive resource for helminth genomics
Open accessAbstract
The number of publicly available parasitic worm genome sequences has increased dramatically in the past three years, and research interest in helminth functional genomics is now quickly gathering pace in response to the foundation that has been laid by these collective efforts. A systematic approach to the organisation, curation, analysis and presentation of these data is clearly vital for maximising the utility of these data to researchers. We have developed a portal called WormBase ParaSite (http://parasite.wormbase.org) for interrogating helminth genomes on a large scale. Data from over 100 nematode and platyhelminth species are integrated, adding value by way of systematic and consistent functional annotation (e.g. protein domains and Gene Ontology terms), gene expression analysis (e.g. alignment of life-stage specific transcriptome data sets), and comparative analysis (e.g. orthologues and paralogues). We provide several ways of exploring the data, including genome browsers, genome and gene summary pages, text search, sequence search, a query wizard, bulk downloads, and programmatic interfaces. In this review, we provide an overview of the back-end infrastructure and analysis behind WormBase ParaSite, and the displays and tools available to users for interrogating helminth genomic data.
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STAR: ultrafast universal RNA-seq aligner
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MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
Katoh, K., & Standley, D. M. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mst010 · Cited by 46,209
Gene Ontology: tool for the unification of biology
Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206
BLAST+: architecture and applications
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BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs
Simão, F. A., Waterhouse, R. M., Ioannidis, P., Kriventseva, E. V., & Zdobnov, E. M. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btv351 · Cited by 13,344
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UniProt: a worldwide hub of protein knowledge
The UniProt Consortium (2019) · Nucleic Acids Research · doi:10.1093/nar/gky1049 · Cited by 7,698
Raudvere, U., Kolberg, L., Kuzmin, I., Arak, T., Adler, P., Peterson, H., & Vilo, J. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz369 · Cited by 5,045
UniProt: the Universal Protein Knowledgebase in 2025
The UniProt Consortium, Bateman, A., Martin, M.-J., Orchard, S., Magrane, M., Adesina, A., Ahmad, S., Bowler-Barnett, E. H., Bye-A-Jee, H., Carpentier, D., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkae1010 · Cited by 2,537
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Kolberg, L., Raudvere, U., Kuzmin, I., Vilo, J., & Peterson, H. (2020) · F1000Research · doi:10.12688/f1000research.24956.2 · Cited by 1,098
Metadata
- Authors
- Howe, K. L., Bolt, B. J., Shafie, M., Kersey, P., & Berriman, M.
- Venue
- Molecular and Biochemical Parasitology
- Publisher
- Elsevier BV
- Published
- 2017-07
- Volume
- 215
- Pages
- 2-10
- ISSN
- 0166-6851 (ISSN-L)
- OpenAlex
- W2559577985
- Cited by
- 745
- References
- 5
- FWCI
- 18.51
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Howe, K. L., Bolt, B. J., Shafie, M., Kersey, P., & Berriman, M. (2017). WormBase ParaSite − a comprehensive resource for helminth genomics. Molecular and Biochemical Parasitology. https://doi.org/10.1016/j.molbiopara.2016.11.005
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