RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway

A chemical method for fast and sensitive detection of DNA synthesis in vivo

Salic, A. N., & Mitchison, T. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712168105 · Cited by 1,859 · see citing works

How Shelterin Protects Mammalian Telomeres

Palm, W., & de Lange, T. (2008) · Annual Review of Genetics · doi:10.1146/annurev.genet.41.110306.130350 · Cited by 1,802 · see citing works

REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

Wold, M. S. (1997) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.66.1.61 · Cited by 1,445 · see citing works

DNA Damage Foci at Dysfunctional Telomeres

Takai, H., Smogorzewska, A., & de Lange, T. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00542-6 · Cited by 1,409 · see citing works

Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans

Baumann, P., & Cech, T. R. (2001) · Science · doi:10.1126/science.1060036 · Cited by 1,028 · see citing works

The POT1-TPP1 telomere complex is a telomerase processivity factor.

Wang, F., Podell, E. R., Zaug, A. J., Yang, Y., Baciu, P., Cech, T. R., & Lei, M. (2007) · Nature · doi:10.1038/nature05454 · Cited by 704 · see citing works

Single-Stranded DNA Arising at Telomeres in cdc13 Mutants May Constitute a Specific Signal for the RAD9 Checkpoint

Garvik, B. M., Carson, M., & Hartwell, L. H. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.11.6128 · Cited by 629 · see citing works

Cdc13p: A Single-Strand Telomeric DNA-Binding Protein with a Dual Role in Yeast Telomere Maintenance

Nugent, C. I., Hughes, T., Lue, N. F., & Lundblad, V. (1996) · Science · doi:10.1126/science.274.5285.249 · Cited by 601 · see citing works

A dynamic model for replication protein A (RPA) function in DNA processing pathways

Fanning, E. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl550 · Cited by 565 · see citing works

Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

Lei, M., Podell, E., & Cech, T. (2004) · Nature Structural &Molecular Biology · doi:10.1038/nsmb867 · Cited by 503 · see citing works

Nucleic acid recognition by OB-fold proteins.

Theobald, D., Mitton-Fry, R. M., & Wuttke, D. (2003) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.32.110601.142506 · Cited by 498 · see citing works

Est1 and Cdc13 as Comediators of Telomerase Access

Evans, S. K., & Lundblad, V. (1999) · Science · doi:10.1126/science.286.5437.117 · Cited by 439 · see citing works

Saccharomyces telomeres acquire single-strand TG1–3 tails late in S phase

Wellinger, R. J., Wolf, A. J., & Zakian, V. A. (1993) · Cell · doi:10.1016/0092-8674(93)90049-v · Cited by 410 · see citing works

Cdc13 Delivers Separate Complexes to the Telomere for End Protection and Replication

Pennock, E., Buckley, K., & Lundblad, V. (2001) · Cell · doi:10.1016/s0092-8674(01)00226-4 · Cited by 408 · see citing works

ALTERED FIDELITY OF MITOTIC CHROMOSOME TRANSMISSION IN CELL CYCLE MUTANTS OF S. CEREVISIAE

Hartwell, L. H., & Smith, D. A. (1985) · Genetics · doi:10.1093/genetics/110.3.381 · Cited by 382 · see citing works

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein.

Qi, H., & Zakian, V. A. (2000) · Europe PMC (PubMed Central) · Cited by 319 · see citing works

The Saccharomyces CDC 13 protein is a single-strand TG 1–3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo

Lin, J., & Zakian, V. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.13760 · Cited by 315 · see citing works

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

Hockemeyer, D., Sfeir, A. J., Shay, J. W., Wright, W. E., & de Lange, T. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600733 · Cited by 314 · see citing works

RPA-like proteins mediate yeast telomere function

Gao, H., Cervantes, R. B., Mandell, E. K., Otero, J. H., & Lundblad, V. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1205 · Cited by 291 · see citing works

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase α and the telomerase-associated Est1 proteinPreprint

Qi, H., & Zakian, V. A. (2000) · Genes & Development · doi:10.1101/gad.14.14.1777 · Cited by 276 · see citing works

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.Preprint

Grandin, N., Reed, S. I., & Charbonneau, M. (1997) · Genes & Development · doi:10.1101/gad.11.4.512 · Cited by 264 · see citing works

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

Grandin, N., Reed, S. I., & Charbonneau, M. (1997) · HAL · Cited by 251 · see citing works

Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

Grandin, N., Damon‐Soubeyrand, C., & Charbonneau, M. (2001) · The EMBO Journal · doi:10.1093/emboj/20.5.1173 · Cited by 249 · see citing works

Telomere-End Processing

Sfeir, A. J., Chai, W., Shay, J. W., & Wright, W. E. (2005) · Molecular Cell · doi:10.1016/j.molcel.2005.02.035 · Cited by 236 · see citing works

A DNA Polymerase-α·Primase Cofactor with Homology to Replication Protein A-32 Regulates DNA Replication in Mammalian Cells*

Casteel, D., Zhuang, S., Zeng, Y., Perrino, F., Boss, G., Goulian, M., & Pilz, R. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m807593200 · Cited by 169 · see citing works

Pol12, the B subunit of DNA polymerase α, functions in both telomere capping and length regulationPreprint

Grossi, S., Puglisi, A., Dmitriev, P., Lopes, M., & Shore, D. (2004) · Genes & Development · doi:10.1101/gad.300004 · Cited by 151 · see citing works

CDC17: An essential gene that prevents telomere elongation in yeast

CARSON, M., & Hartwell, L. H. (1985) · Cell · doi:10.1016/s0092-8674(85)80120-3 · Cited by 148 · see citing works

Loss of hPot1 Function Leads to Telomere Instability and a cut-like Phenotype

Veldman, T., Etheridge, K. T., & Counter, C. M. (2004) · Current Biology · doi:10.1016/j.cub.2004.12.031 · Cited by 144 · see citing works

The Saccharomyces CDC13 is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere in vivo

Lin, J. (1996) · Medical Entomology and Zoology · Cited by 134 · see citing works

Identification of the single-strand telomeric DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein

Hughes, T., Weilbaecher, R. G., Walterscheid, M., & Lundblad, V. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.12.6457 · Cited by 128 · see citing works

Protection of telomeres by a conserved Stn1–Ten1 complex

Martín, V., Du, L., Rozenzhak, S., & Russell, P. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705497104 · Cited by 112 · see citing works

The Function of DNA Polymerase α at Telomeric G Tails Is Important for Telomere Homeostasis

Martin, A. A., Dionne, I., Wellinger, R. J., & Holm, C. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.3.786-796.2000 · Cited by 109 · see citing works

Telomere maintenance and DNA replication: how closely are these two connected?

Chakhparonian, M., & Wellinger, R. J. (2003) · Trends in Genetics · doi:10.1016/s0168-9525(03)00135-5 · Cited by 95 · see citing works

STN1 protects chromosome ends in Arabidopsis thaliana

Song, X., Leehy, K. A., Warrington, R. T., Lamb, J. C., Surovtseva, Y. V., & Shippen, D. E. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0807867105 · Cited by 94 · see citing works

Purification and properties of an accessory protein for DNA polymerase alpha/primase.

Goulian, M., Heard, C. J., & Grimm, S. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38288-2 · Cited by 84 · see citing works

Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p

Petreaca, R. C., Chiu, H.-C., Eckelhoefer, H. A., Chuang, C., Xu, L., & Nugent, C. I. (2006) · Nature Cell Biology · doi:10.1038/ncb1430 · Cited by 77 · see citing works

Alterations of DNA and Chromatin Structures at Telomeres and Genetic Instability in Mouse Cells Defective in DNA Polymerase α

Nakamura, M., Nabetani, A., Mizuno, T., Hanaoka, F., & Ishikawa, F. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.24.11073-11088.2005 · Cited by 43 · see citing works

The telomere syndromes

Armanios, M., & Blackburn, E. H. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3246 · Cited by 982 · see citing works

Identification of seven loci affecting mean telomere length and their association with disease

CARDIoGRAM consortium, Codd, V., Nelson, C. P., Albrecht, E., Mangino, M., Deelen, J., Buxton, J. L., Hottenga, J. J., Fischer, K., Esko, T., et al. (2013) · Nature Genetics · doi:10.1038/ng.2528 · Cited by 933 · see citing works

Telomeres in cancer: tumour suppression and genome instability

Maciejowski, J., & de Lange, T. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.171 · Cited by 745 · see citing works

Genome-wide association identifies <i>OBFC1</i> as a locus involved in human leukocyte telomere biology

Levy, D., Neuhausen, S. L., Hunt, S. C., Kimura, M., Hwang, S.-J., Chen, W., Bis, J. C., Fitzpatrick, A. L., Smith, E., Johnson, A. D., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911494107 · Cited by 259 · see citing works

Roles of telomere biology in cell senescence, replicative and chronological ageing

Liu, J., Wang, L., Wang, Z., & Liu, J.-P. (2019) · Cells · doi:10.3390/cells8010054 · Cited by 164 · see citing works

<i>CTC1</i> Mutations in a patient with dyskeratosis congenita

Keller, R. B., Gagne, K. E., Usmani, G. N., Asdourian, G. K., Williams, D. A., Hofmann, I., & Agarwal, S. (2012) · Pediatric Blood &amp; Cancer · doi:10.1002/pbc.24193 · Cited by 138 · see citing works

The structure of human CST reveals a decameric assembly bound to telomeric DNA

Lim, C. J., Barbour, A. T., Zaug, A. J., Goodrich, K. J., McKay, A. E., Wuttke, D. S., & Cech, T. R. (2020) · Science · doi:10.1126/science.aaz9649 · Cited by 111 · see citing works

A three-state model of telomere control over human proliferative boundaries

Cesare, A. J., & Karlseder, J. (2012) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2012.08.007 · Cited by 106 · see citing works

288 POSTER Selective targeting of critical components of DNA replication by HKH40A (RTA 502)

Michejda, C. J., Kosakowska‐Cholody, T., Meyer, C., et al. (2006) · European Journal of Cancer Supplements · doi:10.1016/s1359-6349(06)70293-2

DNA Replication and the Cell Cycle

Stillman, B., Bell, S. P., Dutta, A., et al. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514320.ch10 · Cited by 32 · see citing works

Changes in the subcellular localization of replication initiation proteins and cell cycle proteins during G1- to S-phase transition in mammalian cells

Br�not-Bosc, F., Gupta, S., Margolis, R. L., et al. (1995) · Chromosoma · doi:10.1007/bf00355316 · Cited by 47 · see citing works

DNA damaged-induced phosphorylation of a viral replicative DNA helicase results in inhibition of DNA replication through attenuation of helicase functionPreprint

Homiski, C., Dey-Rao, R., Shen, S., Qu, J., & Melendy, T. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.29.560221 · Cited by 2 · see citing works

The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication.

Brush, G. S., Anderson, C. W., & Kelly, T. J. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.26.12520 · Cited by 163 · see citing works