The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome
Open accessAbstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause chronic and acute disease. Postacute sequelae of SARS-CoV-2 infection (PASC) include injury to the lungs, heart, kidneys, and brain that may produce a variety of symptoms. PASC also includes a post–coronavirus disease 2019 (COVID-19) syndrome (‘long COVID’) with features that can follow other acute infectious diseases and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Here we summarize what is known about the pathogenesis of ME/CFS and of ‘acute’ COVID-19, and we speculate that the pathogenesis of post–COVID-19 syndrome in some people may be similar to that of ME/CFS. We propose molecular mechanisms that might explain the fatigue and related symptoms in both illnesses, and we suggest a research agenda for both ME/CFS and post–COVID-19 syndrome.
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Cites
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Cited by
Long COVID: major findings, mechanisms and recommendations
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Fatigue and cognitive impairment in Post-COVID-19 Syndrome: a systematic review and meta-analysis
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Unexplained post-acute infection syndromes
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Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
Paul, B. D., Lemle, M. D., Komaroff, A. L., & Snyder, S. H. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2024358118 · Cited by 267
Self-citation
Metadata
- Authors
- Komaroff, A. L., & Lipkin, W. I.
- Venue
- Trends in Molecular Medicine
- Publisher
- Elsevier BV
- Published
- 2021-09
- Volume
- 27
- Issue
- 9
- Pages
- 895-906
- ISSN
- 1471-4914 (ISSN-L)
- OpenAlex
- W3166820281
- Cited by
- 259
- References
- 122
- FWCI
- 7.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome. https://app.cochat.ai/papers/10.1016/j.molmed.2021.06.002
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- Komaroff, A. L., & Lipkin, W. I. (2021). Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome. Trends in Molecular Medicine. https://doi.org/10.1016/j.molmed.2021.06.002
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
