CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

Mechanisms of NAFLD development and therapeutic strategies

Friedman, S. L., Neuschwander-Tetri, B. A., Rinella, M., & Sanyal, A. J. (2018) · Nature Medicine · doi:10.1038/s41591-018-0104-9 · Cited by 4,354 · see citing works

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

Donnelly, K. L., Smith, C. I., Schwarzenberg, S. J., Jessurun, J., Boldt, M. D., & Parks, E. J. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23621 · Cited by 3,604 · see citing works

Mechanisms and disease consequences of nonalcoholic fatty liver disease

Loomba, R., Friedman, S. L., & Shulman, G. I. (2021) · Cell · doi:10.1016/j.cell.2021.04.015 · Cited by 2,002 · see citing works

Protein Sensors for Membrane Sterols

Goldstein, J. L., DeBose‐Boyd, R. A., & Brown, M. S. (2006) · Cell · doi:10.1016/j.cell.2005.12.022 · Cited by 1,677 · see citing works

SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology

Shimano, H., & Sato, R. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2017.91 · Cited by 1,174 · see citing works

Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease

Lambert, J. E., Ramos–Roman, M. A., Browning, J. D., & Parks, E. J. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.11.049 · Cited by 1,069 · cited 1× · see citing works

A Null Mutation in Murine CD36 Reveals an Important Role in Fatty Acid and Lipoprotein Metabolism

Febbraio, M., Abumrad, N. A., Hajjar, D. P., Sharma, K., Cheng, W., Pearce, S. F. A., & Silverstein, R. L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.27.19055 · Cited by 769 · see citing works

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2010) · Physiological Reviews · doi:10.1152/physrev.00003.2009 · Cited by 757 · see citing works

Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease

Softic, S., Cohen, D. E., & Kahn, C. R. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4054-0 · Cited by 709 · see citing works

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

Horton, J. D., Bashmakov, Y. K., Shimomura, I., & Shimano, H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.11.5987 · Cited by 669 · see citing works

Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

Lin, J. D., Yang, R., Tarr, P. T., Wu, P., Handschin, C., Li, S., Yang, W., Pei, L., Uldry, M., Tontonoz, P., et al. (2005) · Cell · doi:10.1016/j.cell.2004.11.043 · Cited by 618 · see citing works

Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease

Kohjima, M., Enjoji, M., Higuchi, N., Kato, M., Kotoh, K., Yoshimoto, T., Fujino, T., Yada, M., Yada, R., Harada, N., et al. (2007) · International Journal of Molecular Medicine · doi:10.3892/ijmm.20.3.351 · Cited by 530 · see citing works

Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity

Koonen, D. P. Y., Jacobs, R. L., Febbraio, M., Young, M. E., Soltys, C.-L. M., Ong, H., Vance, D. E., & Dyck, J. R. B. (2007) · Diabetes · doi:10.2337/db07-0907 · Cited by 514 · see citing works

Retrospective on Cholesterol Homeostasis: The Central Role of Scap

Brown, M. S., Radhakrishnan, A., & Goldstein, J. L. (2017) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-011852 · Cited by 485 · see citing works

Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice

Wilson, C. G., Tran, J. L., Erion, D. M., Vera, N. B., Febbraio, M., & Weiss, E. J. (2015) · Endocrinology · doi:10.1210/en.2015-1866 · Cited by 461 · see citing works

Cholesterol and 25-Hydroxycholesterol Inhibit Activation of SREBPs by Different Mechanisms, Both Involving SCAP and Insigs

Adams, C. M., Reitz, J., Brabander, J. K. D., Feramisco, J. D., Li, L., Brown, M. S., & Goldstein, J. L. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410302200 · Cited by 458 · see citing works

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

Miquilena-Colina, M. E., Lima‐Cabello, E., Sánchez‐Campos, S., García‐Mediavilla, M. V., Fernández‐Bermejo, M., Lozano-Rodríguez, T., Vargas‐Castrillón, J., Buqué, X., Ochoa, B., Aspichueta, P., et al. (2011) · Gut · doi:10.1136/gut.2010.222844 · Cited by 452 · see citing works

Unsaturated Fatty Acids Down-regulate SREBP Isoforms 1a and 1c by Two Mechanisms in HEK-293 Cells

Hannah, V. C., Ou, J., Luong, A., Goldstein, J. L., & Brown, M. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m007273200 · Cited by 448 · see citing works

Cellular fatty acid uptake: a pathway under construction

Su, X., & Abumrad, N. A. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2008.11.001 · Cited by 410 · see citing works

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

Tang, J.-J., Li, J., Qi, W., Qiu, W., Li, P., Li, B.-L., & Song, B. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2010.12.004 · Cited by 409 · see citing works

CD36 tango in cancer: signaling pathways and functions

Wang, J., & Li, Y. (2019) · Theranostics · doi:10.7150/thno.36037 · Cited by 369 · see citing works

Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease

ter Horst, K. W., & Serlie, M. J. M. (2017) · Nutrients · doi:10.3390/nu9090981 · Cited by 365 · see citing works

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

Xu, D., Wang, Z., Xia, Y., Shao, F., Xia, W., Wei, Y., Li, X., Qian, X., Lee, J.-H., Du, L., et al. (2020) · Nature · doi:10.1038/s41586-020-2183-2 · Cited by 360 · see citing works

Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling

Softic, S., Gupta, M. K., Wang, G.-X., Fujisaka, S., O'Neill, B. T., Rao, T. N., Willoughby, J. L. S., Harbison, C. E., Fitzgerald, K. J., Ilkayeva, O., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci94585 · Cited by 349 · see citing works

Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth

Cheng, C., Ru, P., Geng, F., Liu, J., Yoo, J. Y., Wu, X., Cheng, X., Euthine, V., Hu, P., Guo, J. Y., et al. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.09.021 · Cited by 321 · see citing works

CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis

Zhao, L., Zhang, C., Luo, X., Wang, P., Zhou, W., Zhong, S., Xie, Y., Jiang, Y., Yang, P., Tang, R., et al. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.04.006 · Cited by 319 · see citing works

CD36 in chronic kidney disease: novel insights and therapeutic opportunities

Yang, X., Okamura, D. M., Lu, X., Chen, Y., Moorhead, J. F., Varghese, Z., & Ruan, X. Z. (2017) · Nature Reviews Nephrology · doi:10.1038/nrneph.2017.126 · Cited by 264 · see citing works

Promoter Analysis of the Mouse Sterol Regulatory Element-binding Protein-1c Gene

Amemiya-Kudo, M., Shimano, H., Yoshikawa, T., Yahagi, N., Hasty, A. H., Okazaki, H., Tamura, Y., Shionoiri, F., Iizuka, Y., Ohashi, K., et al. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005353200 · Cited by 257 · see citing works

Endothelial cell CD36 optimizes tissue fatty acid uptake

Son, N.-H., Basu, D., Samovski, D., Pietka, T., Peche, V. S., Willecke, F., Fang, X., Yu, S., Scerbo, D. A., Chang, H. R., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci99315 · Cited by 257 · see citing works

Insig Required for Sterol-mediated Inhibition of Scap/SREBP Binding to COPII Proteins in Vitro*♦

Sun, L.-P., Li, L., Goldstein, J. L., & Brown, M. S. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m504041200 · Cited by 251 · see citing works

Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi

Nohturfft, A., DeBose‐Boyd, R. A., Scheek, S., Goldstein, J. L., & Brown, M. S. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.20.11235 · Cited by 244 · see citing works

Regulation of AMPK Activation by CD36 Links Fatty Acid Uptake to β-Oxidation

Samovski, D., Sun, J., Pietka, T., Gross, R. W., Eckel, R. H., Su, X., Stahl, P. D., & Abumrad, N. A. (2014) · Diabetes · doi:10.2337/db14-0582 · Cited by 221 · see citing works

Progress and challenges in the prevention and control of nonalcoholic fatty liver disease

Cai, J., Zhang, X., & Li, H. (2018) · Medicinal Research Reviews · doi:10.1002/med.21515 · Cited by 160 · see citing works

Pathophysiology of Human Genetic CD36 Deficiency

Hirano, K. (2003) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(03)00026-4 · Cited by 158 · see citing works

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

Han, Y., Hu, Z., Cui, A., Liu, Z., Ma, F., Xue, Y., Liu, Y., Zhang, F., Zhao, Z., Yu, Y., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-08585-4 · Cited by 150 · see citing works

Physiological and pathological roles of a multi-ligand receptor CD36 in atherogenesis; insights from CD36-deficient patients

Yamashita, S., Hirano, K., Kuwasako, T., et al. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-005-9031-4 · Cited by 146 · see citing works

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway

Li, Y., Yang, P., Zhao, L., Chen, Y., Zhang, X., Zeng, S., Li, W., Varghese, Z., Moorhead, J. F., Chen, Y., et al. (2019) · Journal of Lipid Research · doi:10.1194/jlr.m090969 · Cited by 144 · see citing works

Free Fatty Acid Uptake in Humans With CD36 Deficiency

Hames, K. C., Vella, A., Kemp, B. J., & Jensen, M. D. (2014) · Diabetes · doi:10.2337/db14-0369 · Cited by 132 · see citing works

Dietary Polyunsaturated Fats Regulate Rat Liver Sterol Regulatory Element Binding Proteins-1 and -2 in Three Distinct Stages and by Different Mechanisms

Xu, J., Cho, H., O'Malley, S. W., Clarke, S. D., & Park, J. H. Y. (2002) · Journal of Nutrition · doi:10.1093/jn/132.11.3333 · Cited by 128 · see citing works

The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis

Moon, Y.-A. (2017) · Endocrinology and Metabolism · doi:10.3803/enm.2017.32.1.6 · Cited by 122 · see citing works

Insulin-induced gene: A new regulator in lipid metabolism

Dong, X., & Tang, S.-Q. (2010) · Peptides · doi:10.1016/j.peptides.2010.07.020 · Cited by 120 · see citing works

CD36 deletion reduces VLDL secretion, modulates liver prostaglandins, and exacerbates hepatic steatosis in ob/ob mice

Nassir, F., Okunade, A. L., Brunt, E. M., & Abumrad, N. A. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m037812 · Cited by 105 · see citing works

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

Hellard, S. L., Theisen, F., Haberhausen, M., Raeder, M. B., Fernø, J., Gebhardt, S., Hinney, A., Remschmidt, H., Krieg, J. C., Mehler‐Wex, C., et al. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002133 · Cited by 102 · see citing works

Isoimmunization against CD36 (glycoprotein IV): description of four cases of neonatal isoimmune thrombocytopenia and brief review of the literature

Curtis, B. R., Ali, S., Glazier, A. M., et al. (2002) · Transfusion · doi:10.1046/j.1537-2995.2002.00176.x · Cited by 96 · see citing works

Insulin Sensitivity and Lipid Metabolism in Human CD36 Deficiency

Furuhashi, M., Ura, N., Nakata, T., & Shimamoto, K. (2003) · Diabetes Care · doi:10.2337/diacare.26.2.471 · Cited by 84 · see citing works

CD36-deficient mice are resistant to alcohol- and high-carbohydrate-induced hepatic steatosis

Clugston, R. D., Yuen, J. J., Hu, Y., Abumrad, N. A., Berk, P. D., Goldberg, I. J., Blaner, W. S., & Huang, L. (2013) · Journal of Lipid Research · doi:10.1194/jlr.m041863 · Cited by 82 · see citing works

CD36 deficiency is frequent and can cause platelet immunization in Africans

Lee, K., Godeau, B., Fromont, P., Plonquet, A., Debili, N., Bachir, D., Reviron, D., Gourin, J., Fernández, E., Galactéros, F., et al. (1999) · Transfusion · doi:10.1046/j.1537-2995.1999.39080873.x · Cited by 79 · see citing works

Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

Bai, J., Xia, M., Xue, Y., Ma, F., Cui, A., Sun, Y., Han, Y., Xu, X., Zhang, F., Hu, Z., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102849 · Cited by 62 · see citing works

Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway

Zhong, S., Zhao, L., Wang, Y., Zhang, C., Liu, J., Wang, P., Zhou, W., Yang, P., Varghese, Z., Moorhead, J. F., et al. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6808 · Cited by 54 · see citing works

Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites

Su, L., Zhou, L., Chen, F., Wang, H., Qian, H., Sheng, Y., Zhu, Y., Yu, H. J., Gong, X., Cai, L., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2018100156 · Cited by 49 · see citing works

Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis

Wang, H., Zhao, M., Sud, N., Christian, P., Shen, J., Song, Y., Pashaj, A., Zhang, K., Carr, T. P., & Su, Q. (2016) · Scientific Reports · doi:10.1038/srep32246 · Cited by 47 · see citing works

Circulating sCD36 levels in patients with non-alcoholic fatty liver disease and controls

Heebøll, S., Poulsen, M. K., Ørnstrup, M. J., Kjær, T. N., Pedersen, S. B., Nielsen, S., Grønbæk, H., & Handberg, A. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.223 · Cited by 34 · see citing works

A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid

Nakakuki, M., Kawano, H., Notsu, T., Imada, K., Mizuguchi, K., & Shimano, H. (2014) · The Journal of Biochemistry · doi:10.1093/jb/mvu019 · Cited by 34 · see citing works

Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR

Yang, P., Zeng, H., Tan, W., et al. (2020) · The FASEB Journal · doi:10.1096/fj.201902777rr · Cited by 24 · see citing works

No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits

Szopa, M., Meirhaeghe, A., Luan, J., Moreno, L. A., González‐Gross, M., Vidal‐Puig, A., Cooper, C. C., Hagen, R., Amouyel, P., Wareham, N. J., et al. (2010) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2010.29422 · Cited by 12 · see citing works

CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis

Yang, P., Qin, H., Li, Y., Xiao, A., Zheng, E., Zeng, H., Su, C., Luo, X., Lu, Q., Liao, M., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33349-y · Cited by 346 · see citing works

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Chen, Y., Du, X., Kuppa, A., Feitosa, M. F., Bielak, L. F., O’Connell, J. R., Musani, S. K., Guo, X., Kahali, B., Chen, V. L., et al. (2023) · Nature Genetics · doi:10.1038/s41588-023-01497-6 · Cited by 215 · see citing works

CD36 favours fat sensing and transport to govern lipid metabolism

Li, Y., Huang, X., Yang, G., Xu, K., Yin, Y., Brecchia, G., & Yin, J. (2022) · Progress in Lipid Research · doi:10.1016/j.plipres.2022.101193 · Cited by 147 · see citing works

Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

Watson, B. R., Paul, B., Rahman, R. U., Amir-Zilberstein, L., Segerstolpe, Å., Epstein, E. T., Murphy, S., Geistlinger, L., Lee, T., Shih, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55325-4 · Cited by 123 · see citing works

The implications of FASN in immune cell biology and related diseases

Xiao, Y., Yang, Y., Xiong, H., & Dong, G. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06463-6 · Cited by 94 · see citing works

Unmasking the enigma of lipid metabolism in metabolic dysfunction-associated steatotic liver disease: from mechanism to the clinic

Rao, G., Peng, X., Li, X., An, K., He, H., Fu, X., Li, S., & An, Z. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1294267 · Cited by 85 · see citing works

Excessive Gluconeogenesis Causes the Hepatic Insulin Resistance Paradox and Its Sequelae

Onyango, A. N. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e12294 · Cited by 79 · see citing works

ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis

Mo, Y., Han, Y., Chen, Y., Chun-ling, F., Li, Q., Liu, Z., Xiao, M., & Xu, B. (2024) · Molecular Cancer · doi:10.1186/s12943-024-02195-5 · Cited by 78 · see citing works

Metabolic-Dysfunction-Associated Steatotic Liver Disease: Molecular Mechanisms, Clinical Implications, and Emerging Therapeutic Strategies

Mejía-Guzmán, J. E., Belmont-Hernández, R. A., Chávez-Tapia, N. C., Uribe, M., & Nuño‐Lámbarri, N. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26072959 · Cited by 72 · see citing works

Insights into the roles and pathomechanisms of ceramide and sphigosine-1-phosphate in nonalcoholic fatty liver disease

Zhu, C., Huai, Q., Zhang, X., Dai, H., Li, X., & Wang, H. (2022) · International Journal of Biological Sciences · doi:10.7150/ijbs.78525 · Cited by 59 · see citing works

Quercetin Regulates Lipid Metabolism and Fat Accumulation by Regulating Inflammatory Responses and Glycometabolism Pathways: A Review

Wang, Y., Li, Z., He, J., & Zhao, Y. (2024) · Nutrients · doi:10.3390/nu16081102 · Cited by 51 · see citing works

Efficacy and underlying mechanisms of berberine against lipid metabolic diseases: a review

Cai, Y., Yang, Q., Yu, Y., Yang, F., Bai, R., & Fan, X. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1283784 · Cited by 46 · see citing works

Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice

Hwang, J., Lee, S., Okada, J., Liu, L. P., Pessin, J. E., Chua, S. C., Schwartz, G. J., & Jo, Y. (2025) · Nature Communications · doi:10.1038/s41467-025-56328-5 · Cited by 42 · see citing works

Biological Mechanisms and Related Natural Inhibitors of CD36 in Nonalcoholic Fatty Liver

Feng, Y., Sun, W., Sun, F., Yin, G., Liang, P., Chen, S., Liu, X., Jiang, T., & Zhang, F. (2022) · Drug Design Development and Therapy · doi:10.2147/dddt.s386982 · Cited by 40 · see citing works

Mechanism of Metabolic Dysfunction-associated Steatotic Liver Disease: Important role of lipid metabolism

Feng, X., Zhang, R., Yang, Z., Zhang, K., & Xing, J. (2024) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2024.00019 · Cited by 41 · see citing works

Sulforaphane Protects against Unilateral Ureteral Obstruction-Induced Renal Damage in Rats by Alleviating Mitochondrial and Lipid Metabolism Impairment

Aranda‐Rivera, A. K., Cruz‐Gregorio, A., Aparicio‐Trejo, O. E., Tapia, E., Sánchez‐Lozada, L. G., García‐Arroyo, F. E., Amador‐Martínez, I., Orozco‐Ibarra, M., Fernández‐Valverde, F., & Pedraza‐Chaverrí, J. (2022) · Antioxidants · doi:10.3390/antiox11101854 · Cited by 39 · see citing works

Betaine Alleviates High-Fat Diet-Induced Disruptionof Hepatic Lipid and Iron Homeostasis in Mice

Li, Y., Jiang, W., Feng, Y. M., Wu, L., Jia, Y., & Zhao, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23116263 · Cited by 37 · see citing works

Acetyl-CoA carboxylase 1 controls a lipid droplet–peroxisome axis and is a vulnerability of endocrine-resistant ER + breast cancer

Bacci, M., Lorito, N., Smiriglia, A., Subbiani, A., Bonechi, F., Comito, G., Morriset, L., Botty, R. E., Benelli, M., López-Velazco, J. I., et al. (2024) · Science Translational Medicine · doi:10.1126/scitranslmed.adf9874 · Cited by 36 · see citing works

Pathogenesis of Alcohol-Associated Fatty Liver: Lessons From Transgenic Mice

Ferdouse, A., & Clugston, R. D. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.940974 · Cited by 32 · see citing works

Intercellular Mitochondrial Transfer: The Novel Therapeutic Mechanism for Diseases

Liu, H., Mao, H., Ouyang, X., Lu, R., & Li, L. (2024) · Traffic · doi:10.1111/tra.12951 · Cited by 31 · see citing works

Current Therapeutical Approaches Targeting Lipid Metabolism in NAFLD

Vitulo, M., Gnodi, E., Rosini, G., Meneveri, R., Giovannoni, R., & Barisani, D. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612748 · Cited by 33 · see citing works

Understanding the role of ursodeoxycholic acid and gut microbiome in non-alcoholic fatty liver disease: current evidence and perspectives

Mao, Q., Lin, B., Zhang, W., Zhang, Y., Zhang, Y., Cao, Q., & Xu, M. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1371574 · Cited by 29 · see citing works

Altered lipid metabolism as a predisposing factor for liver metastasis in MASLD

Kim, S. J., & Hyun, J. (2024) · Molecules and Cells · doi:10.1016/j.mocell.2024.100010 · Cited by 30 · see citing works

The fatty acid receptor CD36 promotes macrophage infiltration via p110γ signaling to stimulate metastasis

Qin, H., Xiao, A., Lu, Q., Li, Y., Luo, X., Zheng, E., Tian, C., Liu, H., Zheng, X., Li, W., et al. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.10.006 · Cited by 29 · see citing works

Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease

Deng, G.-H., Wu, C.-F., Li, Y.-J., Shi, H., Zhong, W., Hong, M., Li, J., Zhao, J.-M., Liu, C., Qin, M., et al. (2023) · Military Medical Research · doi:10.1186/s40779-023-00487-3 · Cited by 27 · see citing works

The remodeling roles of lipid metabolism in colorectal cancer cells and immune microenvironment

Zhong, J., GUO, J., ZHANG, X., FENG, S., Di, W., WANG, Y., & ZHU, H. (2022) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.32604/or.2022.027900 · Cited by 26 · see citing works

Traditional Chinese medicine in the treatment of breast Cancer

Song, P., Liu, T., Zhang, Y., Shao, T., Li, R., Chen, A., Cao, L.-Q., Chen, Z., Guo, W., & Duan, D. (2025) · Molecular Cancer · doi:10.1186/s12943-025-02416-5 · Cited by 27 · see citing works

Cannabidiol improves muscular lipid profile by affecting the expression of fatty acid transporters and inhibiting de novo lipogenesis

Bielawiec, P., Dziemitko, S., Konstantynowicz-Nowicka, K., Chabowski, A., Dzięcioł, J. B., & Harasim‐Symbor, E. (2023) · Scientific Reports · doi:10.1038/s41598-023-30872-w · Cited by 25 · see citing works

Research Progress on the Mechanism of Milk Fat Synthesis in Cows and the Effect of Conjugated Linoleic Acid on Milk Fat Metabolism and Its Underlying Mechanism: A Review

Guo, Y. X., Wei, Z., Zhang, Y., & Cao, J. (2024) · Animals · doi:10.3390/ani14020204 · Cited by 24 · see citing works

Formononetin triggers ferroptosis in triple-negative breast cancer cells by regulating the mTORC1/SREBP1/SCD1 pathway

Xie, D., Jiang, Y., Wang, H., Zhu, L., Huang, S., Liu, S., Zhang, W., & Li, T. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1441105 · Cited by 23 · see citing works

Naringenin cationic lipid-modified nanoparticles mitigate MASLD progression by modulating lipid homeostasis and gut microbiota

Dong, L., Lou, W., Xu, C., & Wang, J. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03228-x · Cited by 23 · see citing works

Dual inhibition of hepatic ACLY and ACSS2: A synergistic approach to combat NAFLD through lipogenesis reduction and mitochondrial enhancement

Zhang, M., Ji, J., Lei, Y., Qin, F., Tao, Y., Li, N., Bian, J., Li, Z., Lai, M., & Qiu, Z. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107706 · Cited by 23 · see citing works

Zuogui-Jiangtang-Qinggan-Fang alleviates high-fat diet-induced type 2 diabetes mellitus with non-alcoholic fatty liver disease by modulating gut microbiome-metabolites-short chain fatty acid composition

Zou, J., Qin, X., Tan, D., Shi, L., Liu, X., Wu, Y., & Yu, R. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.114002 · Cited by 23 · see citing works

γ‐glutamylcysteine alleviates insulin resistance and hepatic steatosis by regulating adenylate cyclase and IGF‐1R/IRS1/PI3K/Akt signaling pathways

Zhou, J., Shi, Y., Yang, C., Lü, S., Zhao, L., Liu, X., Zhou, D., Luo, L., & Yin, Z. (2023) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2023.109404 · Cited by 20 · see citing works

Obesity and Exercise: New Insights and Perspectives

James, N. M., & Stanford, K. I. (2025) · Endocrine Reviews · doi:10.1210/endrev/bnaf017 · Cited by 20 · see citing works

Rhein alleviates hepatic steatosis in NAFLD mice by activating the AMPK/ACC/SREBP1 pathway to enhance lipid metabolism

Dai, W., Hou, Q., & Ye, J. (2025) · Molecular Medicine · doi:10.1186/s10020-025-01304-4 · Cited by 19 · see citing works

Dendritic cell–intrinsic LKB1-AMPK/SIK signaling controls metabolic homeostasis by limiting the hepatic Th17 response during obesity

van der Zande, H. J. P., Brombacher, E. C., Lambooij, J. M., Pelgrom, L. R., Zawistowska‐Deniziak, A., Patente, T. A., Heieis, G. A., Otto, F., Ozir‐Fazalalikhan, A., Yazdanbakhsh, M., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.157948 · Cited by 19 · see citing works

Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non‐alcoholic fatty liver disease

Guha, S., Sesili, S., Mir, I. H., & Thirunavukkarasu, C. (2022) · Cell Biochemistry and Function · doi:10.1002/cbf.3763 · Cited by 18 · see citing works

Preventive and therapeutic effects of natural products and herbal extracts on nonalcoholic fatty liver disease / nonalcoholic steatohepatitis

Cao, Y., Fang, X., Sun, M., Zhang, Y., Shan, M., Lan, X., Zhu, D., & Luo, H. (2023) · Phytotherapy Research · doi:10.1002/ptr.7932 · Cited by 17 · see citing works

Natural compounds proposed for the management of non-alcoholic fatty liver disease

Merenda, T., Juszczak, F., Ferier, E., Duez, P., Patris, S., Declèves, A., & Nachtergael, A. (2024) · Natural Products and Bioprospecting · doi:10.1007/s13659-024-00445-z · Cited by 18 · see citing works

Sesamin ameliorates nonalcoholic hepatic steatosis by inhibiting CD36-mediated hepatocyte lipid accumulation in vitro and in vivo

Bai, Y.-P., Zhang, T., Zhang, T., et al. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116240 · Cited by 17 · see citing works

Comparative effects of viable Lactobacillus rhamnosus GG and its heat‐inactivated paraprobiotic in the prevention of high‐fat high‐fructose diet‐induced non‐alcoholic fatty liver disease in rats

Arellano-García, L., Milton‐Laskibar, I., Martínez, J. A., Arán‐González, M., & Portillo, M. P. (2024) · BioFactors · doi:10.1002/biof.2116 · Cited by 18 · see citing works

Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice

Tye, H., Conos, S. A., Djajawi, T. M., Gottschalk, T. A., Abdoulkader, N., Kong, I. Y., Kammoun, H. L., Narayana, V. K., Kratina, T., Speir, M., et al. (2024) · Life Science Alliance · doi:10.26508/lsa.202302446 · Cited by 17 · see citing works

Single-cell RNA-sequencing reveals a unique landscape of the tumor microenvironment in obesity-associated breast cancer

Zhao, G.-H., Zhang, X., Meng, L.-Y., Dong, K., Shang, S.-P., Jiang, T., Liu, Z., & Gao, H. (2024) · Oncogene · doi:10.1038/s41388-024-03161-7 · Cited by 15 · see citing works

Palmitoylation-dependent modulation of CD36 trafficking and signaling integrates lipid uptake with metabolic disease pathogenesis

Li, M., Jia, H., Zhang, L., Chen, P., Wang, S., Mao, Y., & Yang, Z. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107935 · Cited by 15 · see citing works

Restoring metabolic flexibility: targeting organelle interaction networks in the pathogenesis and therapy of MASLD

Liu, Y., Wang, Y., Zhou, J., Li, H., Liu, C., Zhong, B., Liu, J., Liu, L., Zhang, L., & Sun, L. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1718799 · Cited by 15 · see citing works

CD36 and Its Role in Obesity

García, N. A., Mellergaard, M., Salomón, C., Sepúlveda, P., Kristensen, P. K., & Handberg, A. (2025) · Obesity Reviews · doi:10.1111/obr.70039 · Cited by 16 · see citing works

Examining the Pathogenesis of MAFLD and the Medicinal Properties of Natural Products from a Metabolic Perspective

Fu, Y., Wang, Z., & Qin, H. (2024) · Metabolites · doi:10.3390/metabo14040218 · Cited by 15 · see citing works

Bacillus subtilis HGCC-1 improves growth performance and liver health via regulating gut microbiota in golden pompano

Li, M., Liang, H., Zhang, J., Chen, J., Xu, S., Zhou, W., Ding, Q., Yang, Y., Zhang, Z., Yao, Y., et al. (2025) · Animal Microbiome · doi:10.1186/s42523-024-00372-x · Cited by 15 · see citing works

Efficacy of Glycyrrhetinic Acid in the Treatment of Acne Vulgaris Based on Network Pharmacology and Experimental Validation

Xie, L., Ma, C., Li, X., et al. (2024) · Molecules · doi:10.3390/molecules29102345 · Cited by 14 · see citing works

Dysregulation of the AMPK-SREBP1-FASN axis in MASLD: driving a vicious cycle of lipotoxicity and metabolic-immune crosstalk

Zhao, Q.-Q., Lu, S.-W., Guan, Y., Sun, Z.-W., Qiu, S., & Zhang, A.-H. (2026) · Lipids in Health and Disease · doi:10.1186/s12944-026-02867-9 · Cited by 15 · see citing works

ANGPTL8 deficiency attenuates lipopolysaccharide-induced liver injury by improving lipid metabolic dysregulation

Feng, Y., Luo, S., Fang, C., Ma, S., Fan, D., Chen, Y., Chen, Z., Zheng, X., Tang, Y., Duan, X., et al. (2024) · Journal of Lipid Research · doi:10.1016/j.jlr.2024.100595 · Cited by 15 · see citing works

Hepatocyte-specific SLC27A4 deletion ameliorates nonalcoholic fatty liver disease in mice via suppression of phosphatidylcholine-mediated PXR activation

Shen, C., Pan, Z., Xie, W., Zhao, J., Miao, D., Zhao, L., Liu, M., Zhong, Y., Zhong, C., Gonzalez, F. J., et al. (2024) · Metabolism · doi:10.1016/j.metabol.2024.156054 · Cited by 14 · see citing works

CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice

Chen, M., Zhang, Y., Zeng, S., Li, D., You, M., Zhang, M., Wang, Z., Wei, L., Chen, Y., & Ruan, X. Z. (2023) · iScience · doi:10.1016/j.isci.2023.106524 · Cited by 14 · see citing works

Hepatocyte CD36 protects mice from NASH diet-induced liver injury and fibrosis via blocking N1ICD production

Li, Y., Zhang, L., Jiao, J., Ding, Q., Li, Y., Zhao, Z., Luo, J., Chen, Y., Ruan, X. Z., & Zhao, L. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166800 · Cited by 15 · see citing works

Micropatterned primary hepatocyte co-culture (HEPATOPAC) for fatty liver disease modeling and drug screening

Cottier, K. E., Bhalerao, D., Lewis, C., Gaffney, J., & Heyward, S. A. (2023) · Scientific Reports · doi:10.1038/s41598-023-42785-9 · Cited by 13 · see citing works

KLF4 promotes milk fat synthesis by regulating the PI3K-AKT-mTOR pathway and targeting FASN activation in bovine mammary epithelial cells

Wu, H., Ji, Z., Xie, W., Guo, H., Zheng, Y., Gao, W., & Yuan, B. (2024) · iScience · doi:10.1016/j.isci.2024.109850 · Cited by 13 · see citing works

Mixed exposure to haloacetaldehyde disinfection by-products exacerbates lipid aggregation in the liver of mice

Qiu, M., Yang, L., Jiang, Z., Chen, Y., Liu, Q., Wang, X., & Qu, W. (2024) · Environmental Pollution · doi:10.1016/j.envpol.2024.123971 · Cited by 12 · see citing works

Disinfection Byproducts of Haloacetaldehydes Disrupt Hepatic Lipid Metabolism and Induce Lipotoxicity in High-Fat Culture Conditions

Yang, L., Jiang, Z., Yang, L., Zheng, W., Chen, Y., Qu, F., Crabbe, M. J. C., Zhang, Y., Andersen, M. E., Zheng, Y., et al. (2024) · Environmental Science & Technology · doi:10.1021/acs.est.3c11009 · Cited by 12 · see citing works

Artemisia capillaris Thunb. Water extract alleviates metabolic dysfunction-associated Steatotic liver disease Disease by inhibiting miR-34a-5p to activate Sirt1-mediated hepatic lipid metabolism

Liang, M., Xiao, X., Chen, M., Guo, Y., Han, W., Min, Y., Jiang, X., & Yu, W. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.119030 · Cited by 12 · see citing works

CD36 in liver diseases

Liu, Y., & Yin, W. (2025) · Hepatology Communications · doi:10.1097/hc9.0000000000000623 · Cited by 13 · see citing works

Modulation of Lipid Metabolism and Keap1–Nrf2 Pathway Activation in Macrophages by Targeting PPARγ Affects NAFLD Progression

Chen, Y., Wu, Y., Zhang, Y., Ji, P., & Hua, J. (2025) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.17033 · Cited by 14 · see citing works

What do we know about nutrient-based strategies targeting molecular mechanisms associated with obesity-related fatty liver disease?

Rivera‐Íñiguez, I., Panduro, A., Román, S., & González-Aldaco, K. (2022) · Annals of Hepatology · doi:10.1016/j.aohep.2022.100874 · Cited by 12 · see citing works

Investigating dual inhibition of ACC and CD36 for the treatment of nonalcoholic fatty liver disease in mice

Devereux, C. J., Bayliss, J. A., Keenan, S. N., Montgomery, M. K., & Watt, M. J. (2023) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00161.2022 · Cited by 12 · see citing works

Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

Wu, Z., Luo, L., Kan, Y.-Q., et al. (2023) · Toxics · doi:10.3390/toxics11090736 · Cited by 12 · see citing works

Integration of Transcriptomics and Lipidomics Profiling to Reveal the Therapeutic Mechanism Underlying Ramulus mori (Sangzhi) Alkaloids for the Treatment of Liver Lipid Metabolic Disturbance in High-Fat-Diet/Streptozotocin-Induced Diabetic Mice

Wang, F., Xu, S.-J., Ye, F., Zhang, B., & Sun, X. (2023) · Nutrients · doi:10.3390/nu15183914 · Cited by 12 · see citing works

Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens

Li, L., Lu, Z., Wang, Y., et al. (2023) · Poultry Science · doi:10.1016/j.psj.2023.103251 · Cited by 11 · see citing works

Therapeutic efficacy of mitochondria-targeted esculetin in the improvement of NAFLD-NASH via modulating AMPK-SIRT1 axis.

Singuru, G., Pulipaka, S., Shaikh, A., Andugulapati, S. B., Thennati, R., & Kotamraju, S. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111070 · Cited by 12 · see citing works

Proanthocyanidins-Based Synbiotics as a Novel Strategy for Nonalcoholic Fatty Liver Disease (NAFLD) Risk Reduction

Thilakarathna, W. P. D. W., & Rupasinghe, H. P. V. (2024) · Molecules · doi:10.3390/molecules29030709 · Cited by 11 · see citing works

Exploring the impacts of ketogenic diet on reversible hepatic steatosis: initial analysis in male mice

Ravaut, G., Carneiro, A., & Mounier, C. (2024) · Frontiers in Nutrition · doi:10.3389/fnut.2024.1290540 · Cited by 12 · see citing works

CD36−SREBP1 Axis Mediates TSLP Production in Obesity-Exacerbated Atopic Dermatitis

Yu, J., Song, P., Bai, Y., et al. (2023) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2023.04.024 · Cited by 10 · see citing works

Loss of NAT10 alleviates maternal high‐fat diet‐induced hepatic steatosis in male offspring of mice

Zhang, Q., Zhang, J., Shen, F., et al. (2024) · Obesity · doi:10.1002/oby.24041 · Cited by 10 · see citing works

Chemically synthesized osteocalcin alleviates NAFLD via the AMPK-FOXO1/BCL6-CD36 pathway

Zhang, M., Dong, K., Du, Q., et al. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05592-y · Cited by 10 · see citing works

Mechanisms of metabolic-associated fatty liver disease induced by 48-week PCB138 exposure and theabrownin intervention

Han, J.-R., Liu, C., Chen, Z., Ruan, F., Xue, F., Ye, L., Yu, Y., Zuo, Z., & He, C. (2025) · Environment International · doi:10.1016/j.envint.2025.109780 · Cited by 10 · see citing works

A UPLC-Q-TOF/MS and network pharmacology method to explore the mechanism of Anhua fuzhuan tea intervention in nonalcoholic fatty liver disease

Tian, F., Yi, J., Tang, Y., Chen, B., Long, H., Liu, Y.-F., Ouyang, Y., Zhang, W., Rong-mei, T., & Liu, B. (2023) · Food & Function · doi:10.1039/d2fo02774g · Cited by 9 · see citing works

A host enzyme reduces metabolic dysfunction-associated steatotic liver disease (MASLD) by inactivating intestinal lipopolysaccharide

Wang, Z., Ojogun, N., Liu, Y., Gan, L., Xiao, Z., Feng, J., Jiang, W., Chen, Y., Zou, B., Yu, C., et al. (2024) · eLife · doi:10.7554/elife.100731 · Cited by 17 · see citing works

Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress

Lin, K.-X., Wu, Z., Qin, M.-L., & Zeng, H. (2025) · Toxics · doi:10.3390/toxics13010044 · Cited by 9 · see citing works

Relationship between Abnormal Lipid Metabolism and Gallstone Formation

Li, X., Yin, X., Xu, J., Geng, L., & Liu, Z. (2025) · Korean Journal of Gastroenterology · doi:10.4166/kjg.2024.135 · Cited by 10 · see citing works

Therapeutic strategies targeting SREBP transcription factors: an update to 2024

Wang, Y., Xiao, H., Lai, L., & Zheng, Z. (2025) · Acta Materia Medica · doi:10.15212/amm-2025-0001 · Cited by 9 · see citing works

Metabolic-immune microenvironment crosstalk mediating ICI resistance in MASH-HCC

Ju, Y., Xu, K., Chen, X., Wu, T., & Yuan, Y. (2025) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2025.06.008 · Cited by 11 · see citing works

Suppression of hepatosteatosis by isarubrolone C through AMPK-dependent regulation of lipophagy and lipid metabolism

Chen, B., Ma, Y.-Y., Miao-qing, Z., Zhang, R., Li, S., Wu, L.-Z., & Zhang, J. (2025) · Metabolism · doi:10.1016/j.metabol.2025.156487 · Cited by 9 · see citing works

MnO2 nanoparticles and MnSO4 differentially affected hepatic lipid metabolism through miR-92a/acsl3-dependent de novo lipogenesis in yellow catfish Pelteobagrus fulvidraco

Zhao, T., Zheng, H., Xu, J., Xu, Y.-C., Liu, L.-L., & Luo, Z. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.122416 · Cited by 9 · see citing works

Gallstone and Gallbladder Disease: Biliary Tract and Cholangiopathies

Ceci, L., Han, Y., Krutsinger, K., Baiocchi, L., Wu, N., Kundu, D., Kyritsi, K., Zhou, T., Gaudio, E., Francis, H., et al. (2023) · Comprehensive physiology · doi:10.1002/cphy.c220028 · Cited by 9 · see citing works

Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling

Wu, Y., Li, C., Khan, A. A., Chen, K., Su, R., Xu, S., Sun, Y., Gao, F., Wang, K., Wang, X., et al. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04564-y · Cited by 8 · see citing works

Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease

Swan, J., Szabó, Z., Peters, J., Kummu, O., Kemppi, A., Rahtu‐Korpela, L., Konzack, A., Hakkola, J., Pasternack, A. H., Ritvos, O., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116683 · Cited by 9 · see citing works

Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: primary and secondary gene responses with links to disease progression

Sonkar, R., Ma, H., & Waxman, D. J. (2024) · Toxicological Sciences · doi:10.1093/toxsci/kfae057 · Cited by 7 · see citing works

Crithmum maritimum Extract Restores Lipid Homeostasis and Metabolic Profile of Liver Cancer Cells to a Normal Phenotype

Gnocchi, D., Nikolić, D., Paparella, R. R., Sabbà, C., & Mazzocca, A. (2024) · Plant Foods for Human Nutrition · doi:10.1007/s11130-024-01188-5 · Cited by 7 · see citing works

Insulin-induced gene 2 alleviates ischemia-reperfusion injury in steatotic liver by inhibiting GPX4-dependent ferroptosis

Wu, Y., Li, C., Lu, D., Chen, K., Su, R., Xu, S., Gao, F., Lian, Z., Yang, F., Chen, J., et al. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02406-y · Cited by 7 · see citing works

Spatial genomics: Mapping the landscape of fibrosis

Velu, P. P., Abhari, R. E., & Henderson, N. C. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adm6783 · Cited by 8 · see citing works

Wuwei Ganlu and Myricetin alleviate rheumatoid arthritis by inhibiting M1 macrophage polarization through modulation of SHBG/SREBP1-mediated lipid metabolism

Wen, Y., Wang, Y., Zhuang, Y., Xu, G., Zhang, Y., Zhang, S., Xu, A., Chen, X., Li, K., Cai, W., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.157167 · Cited by 7 · see citing works

EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation

Yang, D., Li, L., Zang, K., et al. (2025) · Research · doi:10.34133/research.1001 · Cited by 7 · see citing works

Low-Iron Diet-Induced Fatty Liver Development Is Microbiota Dependent and Exacerbated by Loss of the Mitochondrial Iron Importer Mitoferrin2

Klag, K. A., Bell, R. S., Jia, X., Seguin, A., Maschek, J. A., Bronner, M. P., Cox, J. E., Round, J. L., & Ward, D. M. (2024) · Nutrients · doi:10.3390/nu16121804 · Cited by 8 · see citing works

Isolation and purification of flavonoids from quinoa whole grain and its inhibitory effect on lipid accumulation in nonalcoholic fatty liver disease by inhibiting the expression of CD36 and FASN

La, X., Zhang, Z., Liang, J., Li, H., Pang, Y., He, X., Kang, Y., Wu, C., & Li, Z. (2024) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13923 · Cited by 7 · see citing works

A host enzyme reduces metabolic dysfunction-associated steatotic liver disease (MASLD) by inactivating intestinal lipopolysaccharide

Wang, Z., Ojogun, N., Liu, Y., Gan, L., Xiao, Z., Feng, J., Jiang, W., Chen, Y., Zou, B., Yu, C., et al. (2025) · eLife · doi:10.7554/elife.100731.3 · Cited by 7 · see citing works

NOD1 activation in 3T3-L1 adipocytes confers lipid accumulation in HepG2 cells

Gulzar, F., Ahmad, S., Singh, S., Kumar, P., Sharma, A., & Tamrakar, A. K. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121400 · Cited by 7 · see citing works

Differential expression of immunoregulatory cytokines in adipose tissue and liver in response to high fat and high sugar diets in female mice

Weiner, J., Dommel, S., Gebhardt, C., Hanschkow, M., Popkova, Y., Krause, K., Klöting, N., Blüher, M., Schiller, J., & Heiker, J. T. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1275160 · Cited by 7 · see citing works

Widespread discordance between mRNA expression, protein abundance and de novo lipogenesis activity in hepatocytes during the fed-starvation transitionPreprint

Landgraf, A., Okada, J., Horton, M., Liu, L. P., Solomon, S., Qiu, Y., Kurland, I. J., Sidoli, S., Pessin, J. E., & Shinoda, K. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.15.649020 · Cited by 7 · see citing works

A mechanistically-anchored and human stem cell-based in vitro test battery for assessing liver steatogenic potential of chemicals

Verhoeven, A., Gatzios, A., Rodrigues, R. M., Sanz-Serrano, J., Kock, J. D., Vinken, M., & Vanhaecke, T. (2025) · Toxicology · doi:10.1016/j.tox.2025.154263 · Cited by 6 · see citing works

Distahlianins A–C: Architecturally Diverse Cadinane-Type Sesquiterpenoid Dimers from Stahlianthus involucratus

Ji, K., Chen, Y., Song, Q., et al. (2025) · Organic Letters · doi:10.1021/acs.orglett.5c03471 · Cited by 6 · see citing works

Chlormequat chloride induces hepatic steatosis by promoting mTOR/SREBP1 mediated lipogenesis via AMPK inhibition

Kang, C., Xiao, Q., Wang, X., Guo, W., Zhang, H., Yuan, L., Zhao, Z., & Hao, W. (2024) · Food and Chemical Toxicology · doi:10.1016/j.fct.2024.114790 · Cited by 6 · see citing works

A new pathway to eSCAPe lipotoxicity

Benhamed, F., & Postic, C. (2017) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2017.10.005 · Cited by 1 · see citing works

Human Sterol Regulatory Element-Binding Protein 1a Contributes Significantly to Hepatic Lipogenic Gene Expression

Bitter, A., Nussler, A. K., Thasler, W. E., Klein, K., Zanger, U. M., Schwab, M. G., & Burk, O. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000369739 · Cited by 28 · see citing works

Abstract 1880: Role of fatty acid synthase and do novo lipogenesis in liver cancer development in mice.

Chen, X., Li, L., Wang, C., et al. (2013) · Cancer Research · doi:10.1158/1538-7445.am2013-1880

Role of CD36 in Palmitic Acid Lipotoxicity in Neuro-2a Neuroblastoma Cells

Urso, C. J., & Zhou, H. (2021) · Biomolecules · doi:10.3390/biom11111567 · Cited by 21 · see citing works

Effects of sterol regulatory element-binding protein (SREBP) in chickens

Alipour, F., & Hassanabadi, A. (2012) · Lipids in Health and Disease · doi:10.1186/1476-511x-11-20 · Cited by 26 · see citing works